Published in J Cell Physiol on July 01, 2009
Polymer nanogels: a versatile nanoscopic drug delivery platform. Adv Drug Deliv Rev (2012) 1.05
Animal models of typical heterotopic ossification. J Biomed Biotechnol (2010) 1.00
Nanogel Carrier Design for Targeted Drug Delivery. J Mater Chem B Mater Biol Med (2014) 0.83
Enhanced bone regeneration in rat calvarial defects implanted with surface-modified and BMP-loaded bioactive glass (13-93) scaffolds. Acta Biomater (2013) 0.81
Engipore acts on human bone marrow stem cells. Saudi Dent J (2010) 0.80
In vivo experimental study on bone regeneration in critical bone defects using PIB nanogels/boron-containing mesoporous bioactive glass composite scaffold. Int J Nanomedicine (2015) 0.78
Therapeutic effect of nanogel-based delivery of soluble FGFR2 with S252W mutation on craniosynostosis. PLoS One (2014) 0.78
The use of total human bone marrow fraction in a direct three-dimensional expansion approach for bone tissue engineering applications: focus on angiogenesis and osteogenesis. Tissue Eng Part A (2014) 0.77
Preparation of resorbable carbonate-substituted hollow hydroxyapatite microspheres and their evaluation in osseous defects in vivo. Mater Sci Eng C Mater Biol Appl (2015) 0.75
Cellularizing hydrogel-based scaffolds to repair bone tissue: How to create a physiologically relevant micro-environment? J Tissue Eng (2017) 0.75
Biodegradable chitosan nanoparticle coatings on titanium for the delivery of BMP-2. Biomolecules (2015) 0.75
Hyaluronic Acid Gel-Based Scaffolds as Potential Carrier for Growth Factors: An In Vitro Bioassay on Its Osteogenic Potential. J Clin Med (2016) 0.75
Peripheral denervation participates in heterotopic ossification in a spinal cord injury model. PLoS One (2017) 0.75
Cross-linked matrix rigidity and soluble retinoids synergize in nuclear lamina regulation of stem cell differentiation. Mol Biol Cell (2017) 0.75
Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Science (2003) 17.57
Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science (2004) 16.26
Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8. Science (2004) 14.80
A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA. Nat Immunol (2005) 7.94
Leptin regulation of bone resorption by the sympathetic nervous system and CART. Nature (2005) 6.43
Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6. Nat Immunol (2004) 5.71
Recognition of pathogen-associated molecular patterns by TLR family. Immunol Lett (2003) 5.27
TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway. Nat Immunol (2003) 4.94
Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4. Nature (2002) 4.81
Osteo-chondroprogenitor cells are derived from Sox9 expressing precursors. Proc Natl Acad Sci U S A (2005) 4.25
Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c+ lamina propria cells. Nat Immunol (2006) 4.15
Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin. J Exp Med (2005) 3.85
Toll-like receptor expression in murine DC subsets: lack of TLR7 expression by CD8 alpha+ DC correlates with unresponsiveness to imidazoquinolines. Eur J Immunol (2003) 3.39
Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein IkappaBzeta. Nature (2004) 3.19
The Toll-like receptor 7 (TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily. Eur J Immunol (2003) 3.17
NFAT and Osterix cooperatively regulate bone formation. Nat Med (2005) 2.99
Interferon-alpha and interleukin-12 are induced differentially by Toll-like receptor 7 ligands in human blood dendritic cell subsets. J Exp Med (2002) 2.96
Decorin regulates assembly of collagen fibrils and acquisition of biomechanical properties during tendon development. J Cell Biochem (2006) 2.71
Malaria blood stage parasites activate human plasmacytoid dendritic cells and murine dendritic cells through a Toll-like receptor 9-dependent pathway. J Immunol (2004) 2.33
NF-kappaB p50 and p52 regulate receptor activator of NF-kappaB ligand (RANKL) and tumor necrosis factor-induced osteoclast precursor differentiation by activating c-Fos and NFATc1. J Biol Chem (2007) 2.22
IkappaB kinase-alpha is critical for interferon-alpha production induced by Toll-like receptors 7 and 9. Nature (2006) 2.16
Activation of TBK1 and IKKvarepsilon kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in the development of interferon antiviral immunity. J Virol (2004) 2.06
Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous cell carcinoma. Cancer Res (2004) 1.98
The novel gene encoding a putative transmembrane protein is mutated in gnathodiaphyseal dysplasia (GDD). Am J Hum Genet (2004) 1.86
TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection. Blood (2008) 1.82
Glycolipid alpha-C-galactosylceramide is a distinct inducer of dendritic cell function during innate and adaptive immune responses of mice. Proc Natl Acad Sci U S A (2006) 1.74
Scleraxis and NFATc regulate the expression of the pro-alpha1(I) collagen gene in tendon fibroblasts. J Biol Chem (2007) 1.72
Involvement of the Toll-like receptor 9 signaling pathway in the induction of innate immunity by baculovirus. J Virol (2005) 1.64
A syndrome of joint laxity and impaired tendon integrity in lumican- and fibromodulin-deficient mice. J Biol Chem (2002) 1.64
Innate Valpha14(+) natural killer T cells mature dendritic cells, leading to strong adaptive immunity. Immunol Rev (2007) 1.62
Negative regulation of Hedgehog signaling by the cholesterogenic enzyme 7-dehydrocholesterol reductase. Development (2006) 1.60
Ihh/Gli2 signaling promotes osteoblast differentiation by regulating Runx2 expression and function. Mol Biol Cell (2007) 1.57
Osteopontin deficiency protects joints against destruction in anti-type II collagen antibody-induced arthritis in mice. Proc Natl Acad Sci U S A (2002) 1.55
Osteoclast-specific Dicer gene deficiency suppresses osteoclastic bone resorption. J Cell Biochem (2010) 1.54
A crucial role for matrix metalloproteinase 2 in osteocytic canalicular formation and bone metabolism. J Biol Chem (2006) 1.52
Cytoplasmic reactive oxygen species and SOD1 regulate bone mass during mechanical unloading. J Bone Miner Res (2013) 1.51
Sarcomas of the oral and maxillofacial region: a review of 32 cases in 25 years. Clin Oral Investig (2004) 1.51
Anabolic action of parathyroid hormone regulated by the β2-adrenergic receptor. Proc Natl Acad Sci U S A (2012) 1.50
Nanogel-based scaffold delivery of prostaglandin E(2) receptor-specific agonist in combination with a low dose of growth factor heals critical-size bone defects in mice. Arthritis Rheum (2011) 1.50
Polysaccharide nanogel gene delivery system with endosome-escaping function: Co-delivery of plasmid DNA and phospholipase A2. J Control Release (2010) 1.47
Nanogel antigenic protein-delivery system for adjuvant-free intranasal vaccines. Nat Mater (2010) 1.45
Elevated skeletal osteopontin levels contribute to the hypophosphatasia phenotype in Akp2(-/-) mice. J Bone Miner Res (2006) 1.39
Mesenchymal stem cells derived from synovium, meniscus, anterior cruciate ligament, and articular chondrocytes share similar gene expression profiles. J Orthop Res (2009) 1.37
An IFN-gamma-IL-18 signaling loop accelerates memory CD8+ T cell proliferation. PLoS One (2008) 1.35
Gene expression within cell-sized lipid vesicles. Chembiochem (2003) 1.34
A comparison of the tube forming potentials of early and late endothelial progenitor cells. Exp Cell Res (2007) 1.32
TGF-beta signaling-mediated morphogenesis: modulation of cell adhesion via cadherin endocytosis. Genes Dev (2007) 1.32
The Ets transcription factor Spi-B is essential for the differentiation of intestinal microfold cells. Nat Immunol (2012) 1.30
Xenopus as a model system to study transcriptional regulatory networks. Proc Natl Acad Sci U S A (2005) 1.28
Unloading induces osteoblastic cell suppression and osteoclastic cell activation to lead to bone loss via sympathetic nervous system. J Biol Chem (2005) 1.27
CLC-3 deficiency leads to phenotypes similar to human neuronal ceroid lipofuscinosis. Genes Cells (2002) 1.20
Self-assembled cationic nanogels for intracellular protein delivery. Bioconjug Chem (2008) 1.18
Phosphorylation-dependent scaffolding role of JSAP1/JIP3 in the ASK1-JNK signaling pathway. A new mode of regulation of the MAP kinase cascade. J Biol Chem (2002) 1.16
Transient receptor potential vanilloid 4 deficiency suppresses unloading-induced bone loss. J Cell Physiol (2008) 1.15
Cytoplasmic superoxide causes bone fragility owing to low-turnover osteoporosis and impaired collagen cross-linking. J Bone Miner Res (2011) 1.12
Transgenic mice expressing a ligand-inducible cre recombinase in osteoblasts and odontoblasts: a new tool to examine physiology and disease of postnatal bone and tooth. Am J Pathol (2004) 1.11
Involvement of FcRgamma in signal transduction of osteoclast-associated receptor (OSCAR). Int Immunol (2004) 1.10
Prognostic significance of cyclin D1 amplification and overexpression in oral squamous cell carcinomas. Oral Oncol (2003) 1.09
Coordinated expression of scleraxis and Sox9 genes during embryonic development of tendons and cartilage. J Orthop Res (2002) 1.09
Osterix, a transcription factor for osteoblast differentiation, mediates antitumor activity in murine osteosarcoma. Cancer Res (2005) 1.09
The nucleocytoplasmic shuttling protein CIZ reduces adult bone mass by inhibiting bone morphogenetic protein-induced bone formation. J Exp Med (2005) 1.08
Identification of a novel human immunodeficiency virus type 1 integrase interactor, Gemin2, that facilitates efficient viral cDNA synthesis in vivo. J Virol (2006) 1.08
Identification of a novel fusion gene in a pre-B acute lymphoblastic leukemia with t(1;19)(q23;p13). Cancer Sci (2004) 1.08
Comprehensive keratin profiling reveals different histopathogenesis of keratocystic odontogenic tumor and orthokeratinized odontogenic cyst. Hum Pathol (2010) 1.07
Treml4, an Ig superfamily member, mediates presentation of several antigens to T cells in vivo, including protective immunity to HER2 protein. J Immunol (2011) 1.07
HER2-specific T-cell immune responses in patients vaccinated with truncated HER2 protein complexed with nanogels of cholesteryl pullulan. Clin Cancer Res (2006) 1.05
Interferon response induced by Toll-like receptor signaling. J Endotoxin Res (2004) 1.05
Resistance to unloading-induced three-dimensional bone loss in osteopontin-deficient mice. J Bone Miner Res (2002) 1.04
Axial protocadherin is a mediator of prenotochord cell sorting in Xenopus. Dev Biol (2002) 1.04
Angiotensin II type 2 receptor blockade increases bone mass. J Biol Chem (2008) 1.03
Histological evidence of the altered distribution of osteocytes and bone matrix synthesis in klotho-deficient mice. Arch Histol Cytol (2005) 1.03
Bone morphogenetic protein-2 enhances osterix gene expression in chondrocytes. J Cell Biochem (2003) 1.03
Lack of Schnurri-2 expression associates with reduced bone remodeling and osteopenia. J Biol Chem (2007) 1.03