Andres Klein-Szanto

Author PubWeight™ 51.31‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Identification of the Rac-GEF P-Rex1 as an essential mediator of ErbB signaling in breast cancer. Mol Cell 2010 2.86
2 Deletion of p120-catenin results in a tumor microenvironment with inflammation and cancer that establishes it as a tumor suppressor gene. Cancer Cell 2011 2.10
3 The MET receptor tyrosine kinase is a potential novel therapeutic target for head and neck squamous cell carcinoma. Cancer Res 2009 2.01
4 Frequent activation of AKT in non-small cell lung carcinomas and preneoplastic bronchial lesions. Carcinogenesis 2004 1.92
5 Clinical implications of fibroblast activation protein in patients with colon cancer. Clin Cancer Res 2007 1.80
6 RAD001 (Everolimus) delays tumor onset and progression in a transgenic mouse model of ovarian cancer. Cancer Res 2007 1.76
7 Chemopotentiation of temozolomide, irinotecan, and cisplatin activity by CEP-6800, a poly(ADP-ribose) polymerase inhibitor. Mol Cancer Ther 2003 1.59
8 NEDD9 promotes oncogenic signaling in mammary tumor development. Cancer Res 2009 1.53
9 Expression of mutant human cystathionine beta-synthase rescues neonatal lethality but not homocystinuria in a mouse model. Hum Mol Genet 2005 1.52
10 Pten loss in the mouse thyroid causes goiter and follicular adenomas: insights into thyroid function and Cowden disease pathogenesis. Cancer Res 2007 1.38
11 Analysis of the in vivo functions of Mrp3. Mol Pharmacol 2005 1.37
12 Cdx1 and c-Myc foster the initiation of transdifferentiation of the normal esophageal squamous epithelium toward Barrett's esophagus. PLoS One 2008 1.34
13 Mouse models of cystathionine beta-synthase deficiency reveal significant threshold effects of hyperhomocysteinemia. FASEB J 2008 1.32
14 Detection of breast cancer in nipple aspirate fluid by CpG island hypermethylation. Clin Cancer Res 2004 1.31
15 Memory CD8+ T cells are gatekeepers of the lymph node draining the site of viral infection. Proc Natl Acad Sci U S A 2007 1.31
16 The codon 72 polymorphism of p53 regulates interaction with NF-{kappa}B and transactivation of genes involved in immunity and inflammation. Mol Cell Biol 2011 1.20
17 Esophageal squamous cell dysplasia and delayed differentiation with deletion of krüppel-like factor 4 in murine esophagus. Gastroenterology 2010 1.13
18 Increased furin activity enhances the malignant phenotype of human head and neck cancer cells. Am J Pathol 2003 1.12
19 Akt-mediated phosphorylation and activation of estrogen receptor alpha is required for endometrial neoplastic transformation in Pten+/- mice. Cancer Res 2006 1.07
20 Characterization of a carcinogenesis rat model of ovarian preneoplasia and neoplasia. Cancer Res 2004 1.07
21 Development of a syngeneic mouse model of epithelial ovarian cancer. J Ovarian Res 2010 1.06
22 Age-dependent morphological alterations of human ovaries from populations with and without BRCA mutations. Gynecol Oncol 2006 1.06
23 Multidrug resistance protein 4 protects bone marrow, thymus, spleen, and intestine from nucleotide analogue-induced damage. Cancer Res 2007 1.04
24 Mice heterozygous for germ-line mutations in methylthioadenosine phosphorylase (MTAP) die prematurely of T-cell lymphoma. Cancer Res 2009 1.04
25 Immune responses of breast cancer patients to mutated epidermal growth factor receptor (EGF-RvIII, Delta EGF-R, and de2-7 EGF-R). J Immunol 2004 1.02
26 CEP-7055: a novel, orally active pan inhibitor of vascular endothelial growth factor receptor tyrosine kinases with potent antiangiogenic activity and antitumor efficacy in preclinical models. Cancer Res 2003 0.98
27 Differential impact of prostaglandin H synthase 1 knockdown on platelets and parturition. J Clin Invest 2005 0.98
28 Multiple mechanisms of telomere maintenance exist in liposarcomas. Clin Cancer Res 2005 0.97
29 Bortezomib induces apoptosis in esophageal squamous cell carcinoma cells through activation of the p38 mitogen-activated protein kinase pathway. Mol Cancer Ther 2008 0.96
30 Biologic markers of breast cancer in nipple aspirate fluid and nipple discharge are associated with clinical findings. Cancer Detect Prev 2007 0.96
31 Cdk2 deficiency decreases ras/CDK4-dependent malignant progression, but not myc-induced tumorigenesis. Cancer Res 2007 0.95
32 Coordinated functions of E-cadherin and transforming growth factor beta receptor II in vitro and in vivo. Cancer Res 2006 0.95
33 Disabled-2 heterozygous mice are predisposed to endometrial and ovarian tumorigenesis and exhibit sex-biased embryonic lethality in a p53-null background. Am J Pathol 2006 0.92
34 Targeting C4-demethylating genes in the cholesterol pathway sensitizes cancer cells to EGF receptor inhibitors via increased EGF receptor degradation. Cancer Discov 2012 0.90
35 Nipple aspirate fluid and ductoscopy to detect breast cancer. Diagn Cytopathol 2010 0.88
36 Combination therapy with 2-difluoromethylornithine and a polyamine transport inhibitor against murine squamous cell carcinoma. Int J Cancer 2006 0.87
37 A reduction of cyclooxygenase 2 gene dosage counters the ovarian morphological aging and tumor phenotype in Wv mice. Am J Pathol 2007 0.87
38 Raloxifene-stimulated experimental breast cancer with the paradoxical actions of estrogen to promote or prevent tumor growth: a unifying concept in anti-hormone resistance. Int J Oncol 2010 0.85
39 The effects of the oral, pan-VEGF-R kinase inhibitor CEP-7055 and chemotherapy in orthotopic models of glioblastoma and colon carcinoma in mice. Mol Cancer Ther 2006 0.83
40 Ductoscopic cytology and image analysis to detect breast carcinoma. Cancer 2004 0.83
41 Retracted Expression of a truncated Hmga1b gene induces gigantism, lipomatosis and B-cell lymphomas in mice. Eur J Cancer 2010 0.78
42 Specific keynote: chemoprevention of ovarian cancer: the journey begins. Gynecol Oncol 2003 0.78
43 Therapy of murine squamous cell carcinomas with 2-difluoromethylornithine. J Carcinog 2004 0.76