Published in Biochim Biophys Acta on March 31, 2009
Cucurbitacin I inhibits Rac1 activation in breast cancer cells by a reactive oxygen species-mediated mechanism and independently of Janus tyrosine kinase 2 and P-Rex1. Mol Pharmacol (2013) 0.94
EGF receptor deletion in podocytes attenuates diabetic nephropathy. J Am Soc Nephrol (2014) 0.93
In scarcity and abundance: metabolic signals regulating cell growth. Physiology (Bethesda) (2013) 0.83
Signal transduction in podocytes--spotlight on receptor tyrosine kinases. Nat Rev Nephrol (2014) 0.82
Epidermal growth factor-induced proliferation of collecting duct cells from Oak Ridge polycystic kidney mice involves activation of Na+/H+ exchanger. Am J Physiol Cell Physiol (2014) 0.77
Roles of Na⁺/H⁺ exchanger type 1 and intracellular pH in angiotensin II-induced reactive oxygen species generation and podocyte apoptosis. J Pharmacol Sci (2013) 0.76
Epidermal growth factor receptor inhibition with erlotinib partially prevents cisplatin-induced nephrotoxicity in rats. PLoS One (2014) 0.75
Absence of miR-146a in podocytes increases risk of diabetic glomerulopathy via upregulation of erbb4 and notch-1. J Biol Chem (2016) 0.75
Lysosome trafficking is necessary for EGF-driven invasion and is regulated by p38 MAPK and Na+/H+ exchangers. BMC Cancer (2017) 0.75
Cell biology of the glomerular podocyte. Physiol Rev (2003) 6.85
Rearrangements of the cytoskeleton and cell contacts induce process formation during differentiation of conditionally immortalized mouse podocyte cell lines. Exp Cell Res (1997) 6.24
Podocyte loss and progressive glomerular injury in type II diabetes. J Clin Invest (1997) 4.83
Getting a foothold in nephrotic syndrome. Nat Genet (2000) 2.68
Activation of Na+/H+ exchange by epidermal growth factor elevates intracellular pH in A431 cells. J Biol Chem (1983) 2.07
A progressive glomerulosclerosis occurring in partial five-sixths nephrectomized rats. Am J Pathol (1975) 1.92
Targeted expression of a dominant-negative EGF-R in the kidney reduces tubulo-interstitial lesions after renal injury. J Clin Invest (2000) 1.68
The Na+/H+ exchanger isoform 1 (NHE1) is a novel member of the calmodulin-binding proteins. Identification and characterization of calmodulin-binding sites. J Biol Chem (1994) 1.60
Na-H exchange-dependent increase in intracellular pH times G2/M entry and transition. J Biol Chem (2003) 1.56
Molecular basis of glomerular permselectivity. Curr Opin Nephrol Hypertens (2001) 1.54
The human epidermal growth factor receptor contains a juxtamembrane calmodulin-binding site. Biochemistry (1998) 1.48
Abnormal polarization of EGF receptors and autocrine stimulation of cyst epithelial growth in human ADPKD. Am J Physiol (1995) 1.48
Regulation of podocyte structure during the development of nephrotic syndrome. J Mol Med (Berl) (1998) 1.45
The NHE1 Na+/H+ exchanger recruits ezrin/radixin/moesin proteins to regulate Akt-dependent cell survival. J Biol Chem (2004) 1.31
Podocyte biology and the emerging understanding of podocyte diseases. Am J Nephrol (2003) 1.31
Alpha-thrombin, epidermal growth factor, and okadaic acid activate the Na+/H+ exchanger, NHE-1, by phosphorylating a set of common sites. J Biol Chem (1991) 1.28
Ion transport proteins anchor and regulate the cytoskeleton. Curr Opin Cell Biol (2002) 1.28
Roles of the podocyte in glomerular function. Am J Physiol Renal Physiol (2000) 1.22
EGF receptor tyrosine kinase inhibition attenuates the development of PKD in Han:SPRD rats. Kidney Int (2003) 1.22
Phosphorylation of calmodulin. Functional implications. Eur J Biochem (2002) 1.21
Combination treatment of PKD utilizing dual inhibition of EGF-receptor activity and ligand bioavailability. Kidney Int (2003) 1.15
Podocyte differentiation and glomerulogenesis. J Am Soc Nephrol (2003) 1.07
EGF receptor ligands are a large fraction of in vitro branching morphogens secreted by embryonic kidney. Am J Physiol (1997) 1.07
Combined inhibition of epidermal growth factor receptor and JAK/STAT pathways results in greater growth inhibition in vitro than single agent therapy. Mol Cancer Ther (2004) 1.07
The role of podocyte injury in the pathogenesis of focal segmental glomerulosclerosis. Ren Fail (2000) 1.00
Update in podocyte biology. Curr Opin Nephrol Hypertens (2001) 1.00
Podocyte detachment and epithelial cell reaction in focal segmental glomerulosclerosis with cellular variants. Kidney Int Suppl (1997) 0.97
The Na+/H+ exchanger isoform 1. Int J Biochem Cell Biol (2005) 0.93
Epidermal growth factor (EGF) receptor kinase-independent signaling by EGF. J Biol Chem (2001) 0.92
New aspects of podocyte cell biology. Kidney Blood Press Res (1997) 0.92
5-HT1A receptor activates Na+/H+ exchange in CHO-K1 cells through Gialpha2 and Gialpha3. J Biol Chem (1997) 0.91
Tyrosine kinase activity of the EGF receptor in murine metanephric organ culture. Kidney Int (1995) 0.87
Integrative effects of EGF on metabolism and proliferation in renal proximal tubular cells. Am J Physiol (1995) 0.87
Hypertonicity activates Na+/H+ exchange through Janus kinase 2 and calmodulin. J Biol Chem (2003) 0.86
Bradykinin B2 receptors activate Na+/H+ exchange in mIMCD-3 cells via Janus kinase 2 and Ca2+/calmodulin. J Biol Chem (2001) 0.85
Rapid activation of sodium-proton exchange and extracellular signal-regulated protein kinase in fibroblasts by G protein-coupled 5-HT1A receptor involves distinct signalling cascades. Biochem J (1998) 0.85
The nephrotic syndrome: from the simple to the complex. Semin Nephrol (1998) 0.84
Cytoplasmic domain of the ubiquitous Na+/H+ exchanger NHE1 can confer Ca2+ responsiveness to the apical isoform NHE3. J Biol Chem (1995) 0.84
Roles of epidermal growth factor and Na+/H+ exchanger-1 in esophageal epithelial defense against acid-induced injury. Am J Physiol Gastrointest Liver Physiol (2005) 0.83
Expression, immunolocalization, and functional activity of Na+/H+ exchanger isoforms in mouse endometrial epithelium. Biol Reprod (2003) 0.83
Mitogen-induced activation of Na+/H+ exchange in vascular smooth muscle cells involves janus kinase 2 and Ca2+/calmodulin. Biochemistry (2003) 0.83
Phosphorylation of calmodulin by the epidermal-growth-factor-receptor tyrosine kinase. Eur J Biochem (1994) 0.81
Epidermal growth factor protects rat epithelial cells against acid-induced damage through the activation of Na+/H+ exchangers. J Pharmacol Exp Ther (1999) 0.81
Epidermal growth factor stimulates proton efflux from chondrocytic cells. J Cell Physiol (2002) 0.80
Kinetic characterization of a stably expressed novel Na+/H+ exchanger (NHE-2). Biochim Biophys Acta (1993) 0.78
Endogenous EGF as a potential renotrophic factor in ischemia-induced acute renal failure. Am J Physiol (1993) 0.78
Comparative phosphorylation of calmodulin from trypanosomatids and bovine brain by calmodulin-binding protein kinases. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol (1998) 0.77
Epidermal growth factor (EGF) increases the renal amino acid transport capacity in amino acid loaded rats. Amino Acids (1998) 0.77
Phosphorylation of calmodulin by permeabilized fibroblasts overexpressing the human epidermal growth factor receptor. Biol Chem (1997) 0.77
Urine biomarkers predict the cause of glomerular disease. J Am Soc Nephrol (2007) 1.98
Characterization of renin-angiotensin system enzyme activities in cultured mouse podocytes. Am J Physiol Renal Physiol (2007) 1.93
Global Decrease of Histone H3K27 Acetylation in ZEB1-Induced Epithelial to Mesenchymal Transition in Lung Cancer Cells. Cancers (Basel) (2013) 1.65
Essential role of c-Cbl in amphiregulin-induced recycling and signaling of the endogenous epidermal growth factor receptor. Biochemistry (2009) 1.16
Helicobacter pylori CagL activates ADAM17 to induce repression of the gastric H, K-ATPase alpha subunit. Gastroenterology (2010) 1.11
Calmodulin interacts with the third intracellular loop of the serotonin 5-hydroxytryptamine1A receptor at two distinct sites: putative role in receptor phosphorylation by protein kinase C. J Biol Chem (2004) 1.09
Translational control of beta2-adrenergic receptor mRNA by T-cell-restricted intracellular antigen-related protein. J Biol Chem (2004) 1.06
Interaction of calmodulin with the serotonin 5-hydroxytryptamine2A receptor. A putative regulator of G protein coupling and receptor phosphorylation by protein kinase C. J Biol Chem (2005) 1.04
Enzymatic processing of angiotensin peptides by human glomerular endothelial cells. Am J Physiol Renal Physiol (2012) 1.04
Critical role of ESCRT machinery in EGFR recycling. Biochemistry (2009) 1.03
Angiotensin I is largely converted to angiotensin (1-7) and angiotensin (2-10) by isolated rat glomeruli. Hypertension (2009) 1.02
Indoxyl sulfate induces complex redox alterations in mesangial cells. Am J Physiol Renal Physiol (2006) 1.02
Identification of a putative nuclear localization sequence within ANG II AT(1A) receptor associated with nuclear activation. Am J Physiol Cell Physiol (2006) 0.98
Sustained receptor stimulation leads to sequestration of recycling endosomes in a classical protein kinase C- and phospholipase D-dependent manner. J Biol Chem (2009) 0.96
Plasma kallikrein promotes epidermal growth factor receptor transactivation and signaling in vascular smooth muscle through direct activation of protease-activated receptors. J Biol Chem (2010) 0.95
Mitogen-induced rapid phosphorylation of serine 795 of the retinoblastoma gene product in vascular smooth muscle cells involves ERK activation. J Biol Chem (2004) 0.94
TRPP2 and TRPV4 form an EGF-activated calcium permeable channel at the apical membrane of renal collecting duct cells. PLoS One (2013) 0.94
Proteomics in renal research. Am J Physiol Renal Physiol (2006) 0.94
ADAM-17 regulates endothelial cell morphology, proliferation, and in vitro angiogenesis. Biochem Biophys Res Commun (2009) 0.94
Bradykinin decreases podocyte permeability through ADAM17-dependent epidermal growth factor receptor activation and zonula occludens-1 rearrangement. J Pharmacol Exp Ther (2010) 0.92
Collecting duct cells that lack normal cilia have mislocalized vasopressin-2 receptors. Am J Physiol Renal Physiol (2011) 0.92
Bradykinin B2 receptor activates extracellular signal-regulated protein kinase in mIMCD-3 cells via epidermal growth factor receptor transactivation. J Pharmacol Exp Ther (2003) 0.91
Identification of proteins in slow continuous ultrafiltrate by reversed-phase chromatography and proteomics. J Proteome Res (2004) 0.88
ERK is regulated by sodium-proton exchanger in rat aortic vascular smooth muscle cells. J Biol Chem (2003) 0.87
Identification of functional bradykinin B(2) receptors endogenously expressed in HEK293 cells. Biochem Pharmacol (2008) 0.87
Oxidative stress in the pathogenesis of experimental mesangial proliferative glomerulonephritis. Am J Physiol Renal Physiol (2003) 0.87
IL-1beta modulation of H,K-ATPase alpha-subunit gene transcription in Helicobacter pylori infection. Am J Physiol Gastrointest Liver Physiol (2007) 0.87
Preventing and responding to complaints of sexual harassment in an academic health center: a 10-year review from the Medical University of South Carolina. Acad Med (2010) 0.87
The 3'-untranslated region of the beta2-adrenergic receptor mRNA regulates receptor synthesis. J Biol Chem (2004) 0.86
A disintegrin and metalloenzyme (ADAM) 17 activation is regulated by α5β1 integrin in kidney mesangial cells. PLoS One (2012) 0.86
Hypertonicity activates Na+/H+ exchange through Janus kinase 2 and calmodulin. J Biol Chem (2003) 0.86
Bradykinin B2 receptor interacts with integrin alpha5beta1 to transactivate epidermal growth factor receptor in kidney cells. Mol Pharmacol (2010) 0.85
Collagenase-2 and -3 mediate epidermal growth factor receptor transactivation by bradykinin B2 receptor in kidney cells. J Pharmacol Exp Ther (2006) 0.85
Serotonin 5-HT1A receptor stimulates c-Jun N-terminal kinase and induces apoptosis in Chinese hamster ovary fibroblasts. Biochim Biophys Acta (2006) 0.84
Mitogen-induced activation of Na+/H+ exchange in vascular smooth muscle cells involves janus kinase 2 and Ca2+/calmodulin. Biochemistry (2003) 0.83
Jak2 and Ca2+/calmodulin are key intermediates for bradykinin B2 receptor-mediated activation of Na+/H+ exchange in KNRK and CHO cells. Assay Drug Dev Technol (2003) 0.83
Telomerase immortalization of principal cells from mouse collecting duct. Am J Physiol Renal Physiol (2010) 0.82
The role of Sp1 in IL-1beta and H. pylori-mediated regulation of H,K-ATPase gene transcription. Am J Physiol Gastrointest Liver Physiol (2008) 0.82
Suppression of GNAI2 message in ovarian cancer. J Ovarian Res (2014) 0.81
Ca2+-calmodulin and janus kinase 2 are required for activation of sodium-proton exchange by the Gi-coupled 5-hydroxytryptamine 1a receptor. J Pharmacol Exp Ther (2006) 0.80
Deletion of airway cilia results in noninflammatory bronchiectasis and hyperreactive airways. Am J Physiol Lung Cell Mol Physiol (2013) 0.79
Novel mechanisms in the regulation of G protein-coupled receptor trafficking to the plasma membrane. J Biol Chem (2010) 0.78
The bradykinin B(2) receptor induces multiple cellular responses leading to the proliferation of human renal carcinoma cell lines. Cancer Manag Res (2012) 0.76
Role of integrins in angiotensin II-induced proliferation of vascular smooth muscle cells. Am J Physiol Cell Physiol (2010) 0.76
Role of c-Cbl carboxyl terminus in serotonin 5-HT2A receptor recycling and resensitization. J Biol Chem (2011) 0.76
Sustained activation of protein kinase C induces delayed phosphorylation and regulates the fate of epidermal growth factor receptor. PLoS One (2013) 0.75
Professor Robert J. Lefkowitz, M.D., scientist and mentor extraordinaire. Assay Drug Dev Technol (2003) 0.75
The Advancing a Healthier Wisconsin Endowment: How a Health Care Conversion Foundation Is Transforming a Medical School. Acad Med (2016) 0.75