Published in Cell Cycle on May 03, 2009
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control. Genes Dev (2007) 13.05
TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth. Cell (2006) 7.49
Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling. Science (2011) 5.73
Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling. EMBO J (2008) 4.79
Spiral waves in disinhibited mammalian neocortex. J Neurosci (2004) 2.27
Cdk5-mediated inhibition of the protective effects of transcription factor MEF2 in neurotoxicity-induced apoptosis. Neuron (2003) 2.19
Spontaneous hepatocarcinogenesis in farnesoid X receptor-null mice. Carcinogenesis (2006) 2.18
Regulation of neuronal survival factor MEF2D by chaperone-mediated autophagy. Science (2009) 2.13
The pollutant diethylhexyl phthalate regulates hepatic energy metabolism via species-specific PPARalpha-dependent mechanisms. Environ Health Perspect (2010) 1.98
Regulation of hepatic stellate cell activation and growth by transcription factor myocyte enhancer factor 2. Gastroenterology (2004) 1.94
Peroxisome proliferator-activated receptor alpha regulates a microRNA-mediated signaling cascade responsible for hepatocellular proliferation. Mol Cell Biol (2007) 1.90
Calpain-regulated p35/cdk5 plays a central role in dopaminergic neuron death through modulation of the transcription factor myocyte enhancer factor 2. J Neurosci (2006) 1.61
ERK5 activation of MEF2-mediated gene expression plays a critical role in BDNF-promoted survival of developing but not mature cortical neurons. Proc Natl Acad Sci U S A (2003) 1.61
Control of MEF2 transcriptional activity by coordinated phosphorylation and sumoylation. J Biol Chem (2005) 1.58
Phosphorylation of ATM by Cdk5 mediates DNA damage signalling and regulates neuronal death. Nat Cell Biol (2009) 1.57
Inter-species transplantation of gut microbiota from human to pigs. ISME J (2007) 1.52
Can maximum urethral closure pressure (MUCP) be used to predict outcome of surgical treatment of stress urinary incontinence? Neurourol Urodyn (2011) 1.44
Identification and functional characterization of ERK/MAPK phosphorylation sites in the Runx2 transcription factor. J Biol Chem (2009) 1.41
What patients think: patient-reported outcomes of retropubic versus trans-obturator mid-urethral slings for urodynamic stress incontinence--a multi-centre randomised controlled trial. Int Urogynecol J (2011) 1.41
Alternative mitochondrial electron transfer as a novel strategy for neuroprotection. J Biol Chem (2011) 1.41
Cyclin-dependent kinase 5 mediates neurotoxin-induced degradation of the transcription factor myocyte enhancer factor 2. J Neurosci (2005) 1.40
Direct regulation of complex I by mitochondrial MEF2D is disrupted in a mouse model of Parkinson disease and in human patients. J Clin Invest (2011) 1.30
Tissue-type plasminogen activator and the low-density lipoprotein receptor-related protein mediate cerebral ischemia-induced nuclear factor-kappaB pathway activation. Am J Pathol (2007) 1.28
Direct analysis of biological tissue by paper spray mass spectrometry. Anal Chem (2011) 1.23
Cdk5-mediated regulation of the PIKE-A-Akt pathway and glioblastoma cell invasion. Proc Natl Acad Sci U S A (2008) 1.22
SP600125, a new JNK inhibitor, protects dopaminergic neurons in the MPTP model of Parkinson's disease. Neurosci Res (2004) 1.18
Interactions between extracellular signal-regulated kinase 1/2 and p38 MAP kinase pathways in the control of RUNX2 phosphorylation and transcriptional activity. J Bone Miner Res (2012) 1.18
Activation of cyclin-dependent kinase 5 by calpains contributes to human immunodeficiency virus-induced neurotoxicity. J Neurochem (2007) 1.16
Identification of noninvasive biomarkers for alcohol-induced liver disease using urinary metabolomics and the Ppara-null mouse. J Proteome Res (2010) 1.13
Diaquabis(2,5-dihydroxybenzoato-kappaO)bis(1,10-phenanthroline-kappa2N,N')strontium(II) bis(1,10-phenanthroline) tetrahydrate. Acta Crystallogr C (2007) 1.13
Bis(pyrimidine-2-carboxyl-ato-κN,O)copper(II). Acta Crystallogr Sect E Struct Rep Online (2007) 1.12
Role of secretoglobin 3A2 in lung development. Am J Respir Crit Care Med (2008) 1.12
Calcium channel and NMDA receptor activities differentially regulate nuclear C/EBPbeta levels to control neuronal survival. Neuron (2003) 1.11
Physical and functional interactions between Runx2 and HIF-1α induce vascular endothelial growth factor gene expression. J Cell Biochem (2011) 1.10
Engineering metal ion coordination to regulate amyloid fibril assembly and toxicity. Proc Natl Acad Sci U S A (2007) 1.10
UPLC-MS-based urine metabolomics reveals indole-3-lactic acid and phenyllactic acid as conserved biomarkers for alcohol-induced liver disease in the Ppara-null mouse model. J Proteome Res (2011) 1.05
Regulation of neuroprotective activity of myocyte-enhancer factor 2 by cAMP-protein kinase A signaling pathway in neuronal survival. J Biol Chem (2005) 1.03
Use of green fluorescent protein to monitor Lactobacillus in the gastro-intestinal tract of chicken. FEMS Microbiol Lett (2007) 1.03
Artificial liver support system in China: a review over the last 30 years. Ther Apher Dial (2006) 1.02
MicroRNA-181b targets cAMP responsive element binding protein 1 in gastric adenocarcinomas. IUBMB Life (2012) 1.02
Chaperone-mediated autophagy: machinery, regulation and biological consequences. Cell Mol Life Sci (2010) 1.01
3D Mn(II) coordination polymer with alternating azide/azide/formate/formate bridged chains: synthesis, structure and magnetic properties. Dalton Trans (2009) 1.01
MicroRNA-372 is down-regulated and targets cyclin-dependent kinase 2 (CDK2) and cyclin A1 in human cervical cancer, which may contribute to tumorigenesis. J Biol Chem (2011) 1.00
Nuclear factor-kappaB (NF-kappaB) is a novel positive transcriptional regulator of the oncogenic Wip1 phosphatase. J Biol Chem (2009) 0.99
AKT and CDK5/p35 mediate brain-derived neurotrophic factor induction of DARPP-32 in medium size spiny neurons in vitro. J Biol Chem (2007) 0.99
Cardioprotective effect of polydatin against ischemia/reperfusion injury: roles of protein kinase C and mito K(ATP) activation. Phytomedicine (2011) 0.98
Tuning the structure and magnetism of azido-mediated Cu(II) systems by coligand modifications. Inorg Chem (2009) 0.98
Identification of candidate genes of QTLs for seed weight in Brassica napus through comparative mapping among Arabidopsis and Brassica species. BMC Genet (2012) 0.97
Identification of a nuclear protein that promotes NF-kappaB activation. Biochem Biophys Res Commun (2003) 0.97
Simultaneous quantitative determination of 9 active components in traditional Chinese medicinal preparation ShuangDan oral liquid by RP-HPLC coupled with photodiode array detection. J Pharm Biomed Anal (2011) 0.96
Phosphorylation of neuronal survival factor MEF2D by glycogen synthase kinase 3beta in neuronal apoptosis. J Biol Chem (2009) 0.96
MicroRNAs: a new key in lung cancer. Cancer Chemother Pharmacol (2014) 0.96
Cardioprotective effect of paeonol and danshensu combination on isoproterenol-induced myocardial injury in rats. PLoS One (2012) 0.95
Anticancer effects of bufalin on human hepatocellular carcinoma HepG2 cells: roles of apoptosis and autophagy. Int J Mol Sci (2013) 0.93
Cis-acting structural element in 5' UTR is essential for infectivity of porcine reproductive and respiratory syndrome virus. Virus Res (2011) 0.93
A modified MELD model for Chinese pre-ACLF and ACLF patients and it reveals poor prognosis in pre-ACLF patients. PLoS One (2013) 0.93
Suppressive effects of swainsonine on C6 glioma cell in vitro and in vivo. Phytomedicine (2009) 0.91
The relationship between liver peroxisome proliferation and adipose tissue atrophy induced by peroxisome proliferator exposure and withdrawal in mice. Biochem Pharmacol (2003) 0.91
Essential role of cytoplasmic cdk5 and Prx2 in multiple ischemic injury models, in vivo. J Neurosci (2009) 0.91
Parkinson disease: a role for autophagy? Neuroscientist (2010) 0.90
Diversity of tight junctions (TJs) between gastrointestinal epithelial cells and their function in maintaining the mucosal barrier. Cell Biol Int (2008) 0.90
Accuracy of an automated breast volume ultrasound system for assessment of the pre-operative extent of pure ductal carcinoma in situ: comparison with a conventional handheld ultrasound examination. Ultrasound Med Biol (2013) 0.90
A three-dimensional supramolecular vanadium hydroxylamide complex: poly[di-mu2-aqua-bis(hydroxylamido)-mu3-malonato-oxidosodiumvanadium(V)]. Acta Crystallogr C (2009) 0.89
Overexpression of DEP domain containing mTOR-interacting protein correlates with poor prognosis in differentiated thyroid carcinoma. Mol Med Rep (2011) 0.89
Conserved TCP domain of Sas-4/CPAP is essential for pericentriolar material tethering during centrosome biogenesis. Proc Natl Acad Sci U S A (2014) 0.89
Long-term gene expression profile dynamics following cecal ligation and puncture in the rat. J Surg Res (2012) 0.88
Co-delivery of PDTC and doxorubicin by multifunctional micellar nanoparticles to achieve active targeted drug delivery and overcome multidrug resistance. Biomaterials (2010) 0.88
PPARalpha-dependent activation of cell cycle control and DNA repair genes in hepatic nonparenchymal cells. Toxicol Sci (2010) 0.88
Controlled release of cisplatin from pH-thermal dual responsive nanogels. Biomaterials (2013) 0.88
Variations in treatment of femoral neck fractures in Alberta. Can J Surg (2002) 0.87
Three-dimensional porous metal-organic frameworks exhibiting metamagnetic behaviors: synthesis, structure, adsorption, and magnetic properties. Inorg Chem (2010) 0.87
The characterization of transaldolase gene tal from Pichia stipitis and its heterologous expression in Fusarium oxysporum. Mol Biol Rep (2010) 0.87
Characterization of the adipose tissue atrophy induced by peroxisome proliferators in mice. Lipids (2002) 0.87
Bursopentin (BP5) from chicken bursa of fabricius attenuates the immune function of dendritic cells. Amino Acids (2014) 0.87
Spatiotemporal patterns of an evoked network oscillation in neocortical slices: coupled local oscillators. J Neurophysiol (2006) 0.87
Studies on chemical modification and biology of a natural product, gambogic acid (III): determination of the essential pharmacophore for biological activity. Eur J Med Chem (2011) 0.87
miR-155 regulates immune modulatory properties of mesenchymal stem cells by targeting TAK1-binding protein 2. J Biol Chem (2013) 0.86
Traditional Chinese medicine for the treatment of primary dysmenorrhea: how do Yuanhu painkillers effectively treat dysmenorrhea? Phytomedicine (2013) 0.86
The stimulatory effect of TLRs ligands on maturation of chicken bone marrow-derived dendritic cells. Vet Immunol Immunopathol (2013) 0.86
Hippocampal endocannabinoids play an important role in induction of long-term potentiation and regulation of contextual fear memory formation. Brain Res Bull (2011) 0.86
Dysregulation of autophagy and Parkinson's disease: the MEF2D link. Apoptosis (2010) 0.85
Modulatory effects of Lactobacillus salivarius on intestinal mucosal immunity of piglets. Curr Microbiol (2011) 0.85
Purification and characterization of a novel antifungal protein from Bacillus subtilis strain B29. J Zhejiang Univ Sci B (2009) 0.85
Effect of artificial liver support system on patients with severe viral hepatitis: a study of four hundred cases. World J Gastroenterol (2004) 0.85
Influence of co-administered danshensu on pharmacokinetic fate and tissue distribution of paeonol in rats. Planta Med (2011) 0.85
Bioinformatics analysis of transcriptional regulation of circadian genes in rat liver. BMC Bioinformatics (2014) 0.85
Impact of burn priming on immune and metabolic functions of whole Liver in a rat cecal ligation and puncture model. Int J Burns Trauma (2013) 0.85
Activation of extrasynaptic NMDA receptors induces LTD in rat hippocampal CA1 neurons. Brain Res Bull (2012) 0.85
Modulating the interaction of CXCR4 and CXCL12 by low-molecular-weight heparin inhibits hepatic metastasis of colon cancer. Invest New Drugs (2010) 0.84
Improving the absorption of earthworm fibrinolytic enzymes with mucosal enhancers. Pharm Biol (2010) 0.84
Agrobacterium tumefaciens mediated transformation of ChiV gene to Trichoderma harzianum. Appl Biochem Biotechnol (2010) 0.84
Chronic supplementation of paeonol combined with danshensu for the improvement of vascular reactivity in the cerebral basilar artery of diabetic rats. Int J Mol Sci (2012) 0.84
Heterologous expression of transaldolase gene Tal from Saccharomyces cerevisiae in Fusarium oxysporum for enhanced bioethanol production. Appl Biochem Biotechnol (2011) 0.84
Mucosal and systemic immune responses induced by recombinant Lactobacillus spp. expressing the hemagglutinin of the avian influenza virus H5N1. Clin Vaccine Immunol (2011) 0.84