David E Graves

Author PubWeight™ 13.51‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Influence of substituent modifications on DNA binding energetics of acridine-based anticancer agents. Biochemistry 2003 1.24
2 Extending nature's leads: the anticancer agent ellipticine. Curr Med Chem Anticancer Agents 2004 1.11
3 Synthesis of the ABC ring system of azaspiracid. 1. Effect of D ring truncation on bis-spirocyclization. Org Lett 2002 1.05
4 Interactions between the etoposide derivative F14512 and human type II topoisomerases: implications for the C4 spermine moiety in promoting enzyme-mediated DNA cleavage. Biochemistry 2011 1.03
5 Synthesis of the ABC ring system of Azaspiracid. 2. A systematic study into the effect of C(16) and C(17) substitution on bis-spirocyclization. Org Lett 2002 1.03
6 Drug interactions with Bacillus anthracis topoisomerase IV: biochemical basis for quinolone action and resistance. Biochemistry 2011 1.01
7 Substituents on etoposide that interact with human topoisomerase IIalpha in the binary enzyme-drug complex: contributions to etoposide binding and activity. Biochemistry 2008 0.99
8 Short DNA sequences and bacterial DNA induce esophageal, gastric, and colorectal cancer cell invasion. APMIS 2012 0.98
9 Topoisomerase II - drug interaction domains: identification of substituents on etoposide that interact with the enzyme. Biochemistry 2007 0.98
10 Amsacrine as a topoisomerase II poison: importance of drug-DNA interactions. Biochemistry 2012 0.90
11 Influence of the amino substituents in the interaction of ethidium bromide with DNA. Biophys J 2004 0.84
12 Antiviral and anticancer optimization studies of the DNA-binding marine natural product aaptamine. Chem Biol Drug Des 2008 0.84
13 Interactions of actinomycin D with human telomeric G-quadruplex DNA. Biochemistry 2009 0.80
14 Contributions of the D-Ring to the activity of etoposide against human topoisomerase IIα: potential interactions with DNA in the ternary enzyme--drug--DNA complex. Biochemistry 2011 0.78