Immunological detection of N-formylkynurenine in oxidized proteins.

PubWeight™: 0.93‹?›

🔗 View Article (PMC 2891935)

Published in Free Radic Biol Med on May 01, 2009

Authors

Marilyn Ehrenshaft1, Sueli Oliveira Silva, Irina Perdivara, Piotr Bilski, Robert H Sik, Colin F Chignell, Kenneth B Tomer, Ronald P Mason

Author Affiliations

1: Laboratory of Pharmacology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA. ehrensh1@niehs.nih.gov

Articles citing this

Oxidative stress induces protein and DNA radical formation in follicular dendritic cells of the germinal center and modulates its cell death patterns in late sepsis. Free Radic Biol Med (2011) 1.04

Oxidative stress and the HIV-infected brain proteome. J Neuroimmune Pharmacol (2013) 0.92

Light-induced oxidative stress, N-formylkynurenine, and oxygenic photosynthesis. PLoS One (2012) 0.82

Partial colocalization of oxidized, N-formylkynurenine-containing proteins in mitochondria and Golgi of keratinocytes. Photochem Photobiol (2010) 0.82

Immunological detection of N-formylkynurenine in porphyrin-mediated photooxided lens α-crystallin. Photochem Photobiol (2011) 0.81

Cardiovascular redox and ox stress proteomics. Antioxid Redox Signal (2012) 0.79

Oxidation of the tryptophan 32 residue of human superoxide dismutase 1 caused by its bicarbonate-dependent peroxidase activity triggers the non-amyloid aggregation of the enzyme. J Biol Chem (2014) 0.79

Targeted oxidation of Torpedo californica acetylcholinesterase by singlet oxygen: identification of N-formylkynurenine tryptophan derivatives within the active-site gorge of its complex with the photosensitizer methylene blue. Biochem J (2012) 0.78

Human indoleamine 2,3-dioxygenase is a catalyst of physiological heme peroxidase reactions: implications for the inhibition of dioxygenase activity by hydrogen peroxide. J Biol Chem (2012) 0.77

Hypericin-mediated photooxidative damage of α-crystallin in human lens epithelial cells. Free Radic Biol Med (2013) 0.77

Tripping up Trp: Modification of protein tryptophan residues by reactive oxygen species, modes of detection, and biological consequences. Free Radic Biol Med (2015) 0.75

Laminin targeting of a peripheral nerve-highlighting peptide enables degenerated nerve visualization. Proc Natl Acad Sci U S A (2016) 0.75

Articles cited by this

Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean? Br J Pharmacol (2004) 5.29

Shotgun identification of protein modifications from protein complexes and lens tissue. Proc Natl Acad Sci U S A (2002) 3.70

Free radical-mediated oxidation of free amino acids and amino acid residues in proteins. Amino Acids (2003) 3.66

Fluorescent and luminescent probes for measurement of oxidative and nitrosative species in cells and tissues: progress, pitfalls, and prospects. Free Radic Biol Med (2007) 3.56

Protein damage and degradation by oxygen radicals. II. Modification of amino acids. J Biol Chem (1987) 2.36

Common molecular signature in SOD1 for both sporadic and familial amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A (2007) 2.25

Singlet oxygen-mediated damage to proteins and its consequences. Biochem Biophys Res Commun (2003) 2.24

Protein aggregation in the brain: the molecular basis for Alzheimer's and Parkinson's diseases. Mol Med (2008) 1.90

How do ALS-associated mutations in superoxide dismutase 1 promote aggregation of the protein? Trends Biochem Sci (2007) 1.77

Protein radical formation on thyroid peroxidase during turnover as detected by immuno-spin trapping. Free Radic Biol Med (2006) 1.67

Vitamin B6 (pyridoxine) and its derivatives are efficient singlet oxygen quenchers and potential fungal antioxidants. Photochem Photobiol (2000) 1.63

Post-translational modifications in the nuclear region of young, aged, and cataract human lenses. J Proteome Res (2007) 1.52

Immunological identification of the heart myoglobin radical formed by hydrogen peroxide. Free Radic Biol Med (2002) 1.52

Oxidative post-translational modification of tryptophan residues in cardiac mitochondrial proteins. J Biol Chem (2003) 1.23

Molecular and cellular aspects of protein misfolding and disease. FASEB J (2008) 1.14

Bicarbonate-dependent peroxidase activity of human Cu,Zn-superoxide dismutase induces covalent aggregation of protein: intermediacy of tryptophan-derived oxidation products. J Biol Chem (2003) 1.13

Tryptophan 32 potentiates aggregation and cytotoxicity of a copper/zinc superoxide dismutase mutant associated with familial amyotrophic lateral sclerosis. J Biol Chem (2007) 1.05

Artifacts associated with the measurement of oxidized DNA bases. Environ Health Perspect (1997) 1.03

Localization of non-essential tryptophan residues for the biological activity of lysozyme. J Mol Biol (1967) 1.00

Protein oxidation in plant mitochondria detected as oxidized tryptophan. Free Radic Biol Med (2005) 0.95

An oxidized tryptophan facilitates copper binding in Methylococcus capsulatus-secreted protein MopE. J Biol Chem (2008) 0.91

Modification of tryptophan and methionine residues is implicated in the oxidative inactivation of surfactant protein B. Biochemistry (2007) 0.91

N-formyl-kynurenine, a tryptophan photooxidation product, as a photodynamic sensitizer. Photochem Photobiol (1974) 0.88

Formation of N-formylkynurenine suggests the involvement of apolipoprotein B-100 centered tryptophan radicals in the initiation of LDL lipid peroxidation. FEBS Lett (1996) 0.86

Tryptophan-14 is the preferred site of DBNBS spin trapping in the self-peroxidation reaction of sperm whale metmyoglobin with a single equivalent of hydrogen peroxide. Chem Res Toxicol (2003) 0.85

Identification of modified tryptophan residues in apolipoprotein B-100 derived from copper ion-oxidized low-density lipoprotein. Biochemistry (1999) 0.84

Mass spectral evidence for carbonate-anion-radical-induced posttranslational modification of tryptophan to kynurenine in human Cu, Zn superoxide dismutase. Free Radic Biol Med (2004) 0.83

Direct evidence for apo B-100-mediated copper reduction: studies with purified apo B-100 and detection of tryptophanyl radicals. Arch Biochem Biophys (2000) 0.82

L-tryptophan radical cation electron spin resonance studies: connecting solution-derived hyperfine coupling constants with protein spectral interpretations. J Am Chem Soc (2008) 0.82

Articles by these authors

Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer. Clin Cancer Res (2005) 5.04

Pseudomonas aeruginosa anaerobic respiration in biofilms: relationships to cystic fibrosis pathogenesis. Dev Cell (2002) 4.94

Cyclooxygenase-2 regulates Th17 cell differentiation during allergic lung inflammation. Am J Respir Crit Care Med (2011) 2.15

The peroxidase activity of mitochondrial superoxide dismutase. Free Radic Biol Med (2012) 2.14

Requirement of arsenic biomethylation for oxidative DNA damage. J Natl Cancer Inst (2009) 1.96

Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice. FASEB J (2010) 1.82

Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice. J Clin Invest (2011) 1.74

Mitochondrial dysfunction in SOD1G93A-bearing astrocytes promotes motor neuron degeneration: prevention by mitochondrial-targeted antioxidants. J Neurosci (2008) 1.72

Protein radical formation on thyroid peroxidase during turnover as detected by immuno-spin trapping. Free Radic Biol Med (2006) 1.67

The oxidation of 2',7'-dichlorofluorescin to reactive oxygen species: a self-fulfilling prophesy? Free Radic Biol Med (2005) 1.60

Inducible nitric oxide synthase is required in alcohol-induced liver injury: studies with knockout mice. Gastroenterology (2003) 1.59

Activation of the androgen receptor by intratumoral bioconversion of androstanediol to dihydrotestosterone in prostate cancer. Cancer Res (2011) 1.58

Immunological identification of the heart myoglobin radical formed by hydrogen peroxide. Free Radic Biol Med (2002) 1.52

Identification of human whole saliva protein components using proteomics. Proteomics (2004) 1.51

HMGB1 is a cofactor in mammalian base excision repair. Mol Cell (2007) 1.49

Endothelial CYP epoxygenase overexpression and soluble epoxide hydrolase disruption attenuate acute vascular inflammatory responses in mice. FASEB J (2010) 1.48

Cytotoxic action of juglone and plumbagin: a mechanistic study using HaCaT keratinocytes. Chem Res Toxicol (2004) 1.48

The photosensitizing potential of compact fluorescent vs incandescent light bulbs. Photochem Photobiol (2008) 1.43

In vivo lipid-derived free radical formation by NADPH oxidase in acute lung injury induced by lipopolysaccharide: a model for ARDS. FASEB J (2002) 1.42

DNA damage induced by methylated trivalent arsenicals is mediated by reactive oxygen species. Chem Res Toxicol (2002) 1.39

Characterization of glycopeptides from HIV-I(SF2) gp120 by liquid chromatography mass spectrometry. J Am Soc Mass Spectrom (2004) 1.37

Neuromelanin activates microglia and induces degeneration of dopaminergic neurons: implications for progression of Parkinson's disease. Neurotox Res (2009) 1.35

Endothelial expression of human cytochrome P450 epoxygenase CYP2C8 increases susceptibility to ischemia-reperfusion injury in isolated mouse heart. FASEB J (2011) 1.33

Identification of the anti-inflammatory protein tristetraprolin as a hyperphosphorylated protein by mass spectrometry and site-directed mutagenesis. Biochem J (2006) 1.26

Elucidation of O-glycosylation structures of the beta-amyloid precursor protein by liquid chromatography-mass spectrometry using electron transfer dissociation and collision induced dissociation. J Proteome Res (2009) 1.24

Delayed and sustained activation of extracellular signal-regulated kinase in human keratinocytes by UVA: implications in carcinogenesis. J Biol Chem (2004) 1.22

Identification of free radicals on hemoglobin from its self-peroxidation using mass spectrometry and immuno-spin trapping: observation of a histidinyl radical. J Biol Chem (2003) 1.22

Low level, long-term inorganic arsenite exposure causes generalized resistance to apoptosis in cultured human keratinocytes: potential role in skin co-carcinogenesis. Int J Cancer (2005) 1.21

Protein oxidation of cytochrome C by reactive halogen species enhances its peroxidase activity. J Biol Chem (2002) 1.13

UVA-induced cell cycle progression is mediated by a disintegrin and metalloprotease/epidermal growth factor receptor/AKT/Cyclin D1 pathways in keratinocytes. Cancer Res (2008) 1.12

Immunochemical detection of hemoglobin-derived radicals formed by reaction with hydrogen peroxide: involvement of a protein-tyrosyl radical. Free Radic Biol Med (2003) 1.11

A novel protocol to identify and quantify all spin trapped free radicals from in vitro/in vivo interaction of HO(.-) and DMSO: LC/ESR, LC/MS, and dual spin trapping combinations. Free Radic Biol Med (2005) 1.10

Noninvasive diagnostic tool for inflammation-induced oxidative stress using electron spin resonance spectroscopy and an extracellular cyclic hydroxylamine. Arch Biochem Biophys (2002) 1.09

Identification of the myoglobin tyrosyl radical by immuno-spin trapping and its dimerization. Free Radic Biol Med (2005) 1.09

Immuno-spin trapping of a post-translational carboxypeptidase B1 radical formed by a dual role of xanthine oxidase and endothelial nitric oxide synthase in acute septic mice. Free Radic Biol Med (2008) 1.08

Electron transfer between a tyrosyl radical and a cysteine residue in hemoproteins: spin trapping analysis. J Am Chem Soc (2007) 1.08

Epoxyeicosanoids promote organ and tissue regeneration. Proc Natl Acad Sci U S A (2013) 1.08

Free radical production requires both inducible nitric oxide synthase and xanthine oxidase in LPS-treated skin. Proc Natl Acad Sci U S A (2006) 1.08

Evaluation of cytochrome P450-derived eicosanoids in humans with stable atherosclerotic cardiovascular disease. Atherosclerosis (2012) 1.07

Immuno-spin trapping of DNA radicals. Nat Methods (2006) 1.07

Quantitative proteomics analysis of macrophage rafts reveals compartmentalized activation of the proteasome and of proteasome-mediated ERK activation in response to lipopolysaccharide. Mol Cell Proteomics (2008) 1.07

Immunolocalization of hypochlorite-induced, catalase-bound free radical formation in mouse hepatocytes. Free Radic Biol Med (2006) 1.07

Copper-catalyzed protein oxidation and its modulation by carbon dioxide: enhancement of protein radicals in cells. J Biol Chem (2005) 1.06

Role of reduced glutathione efflux in apoptosis of immortalized human keratinocytes induced by UVA. J Biol Chem (2002) 1.06

Separation and identification of DMPO adducts of oxygen-centered radicals formed from organic hydroperoxides by HPLC-ESR, ESI-MS and MS/MS. J Am Soc Mass Spectrom (2003) 1.06

Photooxidation of Amplex Red to resorufin: implications of exposing the Amplex Red assay to light. Free Radic Biol Med (2012) 1.05

Oxidative stress induces protein and DNA radical formation in follicular dendritic cells of the germinal center and modulates its cell death patterns in late sepsis. Free Radic Biol Med (2011) 1.04

Immuno-spin trapping analyses of DNA radicals. Nat Protoc (2007) 1.04

Leptin is key to peroxynitrite-mediated oxidative stress and Kupffer cell activation in experimental non-alcoholic steatohepatitis. J Hepatol (2012) 1.04

Constitutive nitric oxide synthase activation is a significant route for nitroglycerin-mediated vasodilation. Proc Natl Acad Sci U S A (2008) 1.04

Lysyl hydroxylase 3-mediated glucosylation in type I collagen: molecular loci and biological significance. J Biol Chem (2012) 1.03

The role of A2E in prevention or enhancement of light damage in human retinal pigment epithelial cells. Photochem Photobiol (2002) 1.03

Involvement of protein radical, protein aggregation, and effects on NO metabolism in the hypochlorite-mediated oxidation of mitochondrial cytochrome c. Free Radic Biol Med (2004) 1.03

Involvement of inducible nitric oxide synthase in hydroxyl radical-mediated lipid peroxidation in streptozotocin-induced diabetes. Free Radic Biol Med (2008) 1.03

Pristine (C60) and hydroxylated [C60(OH)24] fullerene phototoxicity towards HaCaT keratinocytes: type I vs type II mechanisms. Chem Res Toxicol (2008) 1.03

Mass spectrometric characterization of glycosylation of hepatitis C virus E2 envelope glycoprotein reveals extended microheterogeneity of N-glycans. J Am Soc Mass Spectrom (2007) 1.02

Analysis of the oxidative damage-induced conformational changes of apo- and holocalmodulin by dose-dependent protein oxidative surface mapping. Biophys J (2006) 1.02

Proteomic profiling of S-acylated macrophage proteins identifies a role for palmitoylation in mitochondrial targeting of phospholipid scramblase 3. Mol Cell Proteomics (2011) 1.02

Identification of protein-derived tyrosyl radical in the reaction of cytochrome c and hydrogen peroxide: characterization by ESR spin-trapping, HPLC and MS. Biochem J (2002) 1.02

Direct evidence of iNOS-mediated in vivo free radical production and protein oxidation in acetone-induced ketosis. Am J Physiol Endocrinol Metab (2008) 1.02

CEBS object model for systems biology data, SysBio-OM. Bioinformatics (2004) 1.02

Enhanced photodynamic efficacy towards melanoma cells by encapsulation of Pc4 in silica nanoparticles. Toxicol Appl Pharmacol (2009) 1.02

Site-specific radical formation in DNA induced by Cu(II)-H₂O₂ oxidizing system, using ESR, immuno-spin trapping, LC-MS, and MS/MS. Free Radic Biol Med (2011) 1.02

Mechanism of hydrogen peroxide-induced Cu,Zn-superoxide dismutase-centered radical formation as explored by immuno-spin trapping: the role of copper- and carbonate radical anion-mediated oxidations. Free Radic Biol Med (2005) 1.02

Immuno-spin trapping of protein and DNA radicals: "tagging" free radicals to locate and understand the redox process. Free Radic Biol Med (2009) 1.01

Lysyl hydroxylase 3 glucosylates galactosylhydroxylysine residues in type I collagen in osteoblast culture. J Biol Chem (2011) 1.01

Epidermal growth factor receptor down-regulation induced by UVA in human keratinocytes does not require the receptor kinase activity. J Biol Chem (2003) 1.01

Photoaffinity labeling combined with mass spectrometric approaches as a tool for structural proteomics. Expert Rev Proteomics (2006) 1.00

Identification of protein radicals formed in the human neuroglobin-H2O2 reaction using immuno-spin trapping and mass spectrometry. Biochemistry (2008) 1.00

Spin trapping investigation of peroxide- and isoniazid-induced radicals in Mycobacterium tuberculosis catalase-peroxidase. Biochemistry (2008) 0.99

Reaction of human hemoglobin with peroxynitrite. Isomerization to nitrate and secondary formation of protein radicals. J Biol Chem (2003) 0.99

Prevention of hepatic ischemia-reperfusion injury by green tea extract. Am J Physiol Gastrointest Liver Physiol (2002) 0.99

Phototoxicity and cytotoxicity of fullerol in human lens epithelial cells. Toxicol Appl Pharmacol (2007) 0.98

Identification of all classes of spin-trapped carbon-centered radicals in soybean lipoxygenase-dependent lipid peroxidations of omega-6 polyunsaturated fatty acids via LC/ESR, LC/MS, and tandem MS. Free Radic Biol Med (2003) 0.98

Phototoxicity of nano titanium dioxides in HaCaT keratinocytes--generation of reactive oxygen species and cell damage. Toxicol Appl Pharmacol (2012) 0.97

Prostaglandin E₂ protects murine lungs from bleomycin-induced pulmonary fibrosis and lung dysfunction. Am J Physiol Lung Cell Mol Physiol (2011) 0.97

Two-dimensional electrophoresis study of in vitro pellicle formation and dental caries susceptibility. Eur J Oral Sci (2006) 0.97

Free radical-dependent dysfunction of small-for-size rat liver grafts: prevention by plant polyphenols. Gastroenterology (2005) 0.97

Alterations in the rat serum proteome during liver injury from acetaminophen exposure. J Pharmacol Exp Ther (2006) 0.97

Determination of protein-derived epitopes by mass spectrometry. Expert Rev Proteomics (2005) 0.97

Formation of reactive sulfite-derived free radicals by the activation of human neutrophils: an ESR study. Free Radic Biol Med (2012) 0.96

The Mechanism by which 4-hydroxy-2,2,6,6-tetramethylpiperidene-1-oxyl (tempol) diverts peroxynitrite decomposition from nitrating to nitrosating species. Chem Res Toxicol (2002) 0.96