PubRank

Thomas Langer

Author PubWeight™ 131.56‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The m-AAA protease defective in hereditary spastic paraplegia controls ribosome assembly in mitochondria. Cell 2005 3.72
2 SLP-2 is required for stress-induced mitochondrial hyperfusion. EMBO J 2009 3.61
3 Quality control of mitochondria: protection against neurodegeneration and ageing. EMBO J 2008 3.39
4 Prohibitins control cell proliferation and apoptosis by regulating OPA1-dependent cristae morphogenesis in mitochondria. Genes Dev 2008 2.76
5 Mutations in the mitochondrial protease gene AFG3L2 cause dominant hereditary ataxia SCA28. Nat Genet 2010 2.66
6 Regulation of OPA1 processing and mitochondrial fusion by m-AAA protease isoenzymes and OMA1. J Cell Biol 2009 2.65
7 Making heads or tails of phospholipids in mitochondria. J Cell Biol 2011 2.55
8 The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria. J Cell Biol 2009 2.22
9 Protein degradation within mitochondria: versatile activities of AAA proteases and other peptidases. Crit Rev Biochem Mol Biol 2007 2.18
10 Lung stress and strain during mechanical ventilation: any difference between statics and dynamics? Crit Care Med 2013 2.14
11 The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO. Mol Cell 2013 2.12
12 An intersubunit signaling network coordinates ATP hydrolysis by m-AAA proteases. Mol Cell 2009 2.12
13 Variable and tissue-specific subunit composition of mitochondrial m-AAA protease complexes linked to hereditary spastic paraplegia. Mol Cell Biol 2006 2.00
14 Maternal and offspring pools of osteocalcin influence brain development and functions. Cell 2013 2.00
15 Prohibitin function within mitochondria: essential roles for cell proliferation and cristae morphogenesis. Biochim Biophys Acta 2008 1.96
16 Loss of m-AAA protease in mitochondria causes complex I deficiency and increased sensitivity to oxidative stress in hereditary spastic paraplegia. J Cell Biol 2003 1.95
17 Formation of membrane-bound ring complexes by prohibitins in mitochondria. Mol Biol Cell 2004 1.92
18 Two deubiquitylases act on mitofusin and regulate mitochondrial fusion along independent pathways. Mol Cell 2013 1.90
19 OPA1 processing reconstituted in yeast depends on the subunit composition of the m-AAA protease in mitochondria. Mol Biol Cell 2007 1.87
20 Mitochondrial quality control: a matter of life and death for neurons. EMBO J 2012 1.83
21 Lung stress and strain during mechanical ventilation: any safe threshold? Am J Respir Crit Care Med 2011 1.77
22 NMR characterization of kinase p38 dynamics in free and ligand-bound forms. Angew Chem Int Ed Engl 2006 1.61
23 Membrane protein degradation by AAA proteases in mitochondria. Biochim Biophys Acta 2002 1.57
24 Quality control of mitochondrial proteostasis. Cold Spring Harb Perspect Biol 2011 1.55
25 Time to generate ventilator-induced lung injury among mammals with healthy lungs: a unifying hypothesis. Intensive Care Med 2011 1.55
26 m-AAA protease-driven membrane dislocation allows intramembrane cleavage by rhomboid in mitochondria. EMBO J 2007 1.54
27 Whole-exome sequencing identifies homozygous AFG3L2 mutations in a spastic ataxia-neuropathy syndrome linked to mitochondrial m-AAA proteases. PLoS Genet 2011 1.54
28 Characterization of peptides released from mitochondria: evidence for constant proteolysis and peptide efflux. J Biol Chem 2004 1.53
29 Impaired folding of the mitochondrial small TIM chaperones induces clearance by the i-AAA protease. J Mol Biol 2012 1.51
30 Prohibitins and the functional compartmentalization of mitochondrial membranes. J Cell Sci 2009 1.49
31 Effects of reduced dialysate calcium on calcium-phosphorus product and bone metabolism in hemodialysis patients. Nephron Clin Pract 2004 1.46
32 Regulation of mitochondrial fusion by the F-box protein Mdm30 involves proteasome-independent turnover of Fzo1. J Cell Biol 2006 1.44
33 Oma1, a novel membrane-bound metallopeptidase in mitochondria with activities overlapping with the m-AAA protease. J Biol Chem 2003 1.42
34 Intramitochondrial transport of phosphatidic acid in yeast by a lipid transfer protein. Science 2012 1.36
35 The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission. J Cell Biol 2014 1.34
36 Clinical review: Extracorporeal membrane oxygenation. Crit Care 2011 1.34
37 A mitochondrial phosphatase required for cardiolipin biosynthesis: the PGP phosphatase Gep4. EMBO J 2010 1.26
38 Prohibitins interact genetically with Atp23, a novel processing peptidase and chaperone for the F1Fo-ATP synthase. Mol Biol Cell 2006 1.26
39 Using wavelet de-noised spectra in NMR screening. J Magn Reson 2005 1.25
40 Translating m-AAA protease function in mitochondria to hereditary spastic paraplegia. Trends Mol Med 2006 1.24
41 Regulation of mitochondrial phospholipids by Ups1/PRELI-like proteins depends on proteolysis and Mdm35. EMBO J 2010 1.24
42 AAA proteases in mitochondria: diverse functions of membrane-bound proteolytic machines. Res Microbiol 2009 1.22
43 Nonredundant roles of mitochondria-associated F-box proteins Mfb1 and Mdm30 in maintenance of mitochondrial morphology in yeast. Mol Biol Cell 2006 1.19
44 Emerging health technologies: informing and supporting health policy early. Health Policy 2008 1.18
45 TRIAP1/PRELI complexes prevent apoptosis by mediating intramitochondrial transport of phosphatidic acid. Cell Metab 2013 1.16
46 Stress-induced OMA1 activation and autocatalytic turnover regulate OPA1-dependent mitochondrial dynamics. EMBO J 2014 1.15
47 Mitofusin 2 builds a bridge between ER and mitochondria. Cell 2008 1.14
48 Autocatalytic processing of m-AAA protease subunits in mitochondria. Mol Biol Cell 2009 1.11
49 Functional evaluation of paraplegin mutations by a yeast complementation assay. Hum Mutat 2010 1.09
50 Role of the novel metallopeptidase Mop112 and saccharolysin for the complete degradation of proteins residing in different subcompartments of mitochondria. J Biol Chem 2005 1.08
51 Ugo1 and Mdm30 act sequentially during Fzo1-mediated mitochondrial outer membrane fusion. J Cell Sci 2011 1.07
52 Loss of prohibitin membrane scaffolds impairs mitochondrial architecture and leads to tau hyperphosphorylation and neurodegeneration. PLoS Genet 2012 1.07
53 Substrate recognition by AAA+ ATPases: distinct substrate binding modes in ATP-dependent protease Yme1 of the mitochondrial intermembrane space. Mol Cell Biol 2007 1.04
54 Substrate specific consequences of central pore mutations in the i-AAA protease Yme1 on substrate engagement. J Struct Biol 2006 1.03
55 The mitochondrial electron transport chain is dispensable for proliferation and differentiation of epidermal progenitor cells. Stem Cells 2011 1.03
56 Mitochondrial AAA proteases--towards a molecular understanding of membrane-bound proteolytic machines. Biochim Biophys Acta 2011 1.02
57 Studying proteolysis within mitochondria. Methods Mol Biol 2007 1.01
58 NMR analysis of a Tau phosphorylation pattern. J Am Chem Soc 2006 1.00
59 The human Cdc37.Hsp90 complex studied by heteronuclear NMR spectroscopy. J Biol Chem 2008 1.00
60 Evidence for a novel mitochondria-to-nucleus signalling pathway in respiring cells lacking i-AAA protease and the ABC-transporter Mdl1. Gene 2006 0.98
61 Towards ultraprotective mechanical ventilation. Curr Opin Anaesthesiol 2012 0.96
62 Proteolytic control of mitochondrial function and morphogenesis. Biochim Biophys Acta 2012 0.96
63 Discovery of Mycobacterium tuberculosis protein tyrosine phosphatase A (MptpA) inhibitors based on natural products and a fragment-based approach. Chembiochem 2005 0.96
64 AFG3L2 supports mitochondrial protein synthesis and Purkinje cell survival. J Clin Invest 2012 0.95
65 Presequence-dependent folding ensures MrpL32 processing by the m-AAA protease in mitochondria. EMBO J 2011 0.94
66 Membrane protein turnover by the m-AAA protease in mitochondria depends on the transmembrane domains of its subunits. EMBO Rep 2004 0.94
67 Electron cryomicroscopy structure of a membrane-anchored mitochondrial AAA protease. J Biol Chem 2010 0.93
68 NMR backbone assignment of the mitogen-activated protein (MAP) kinase p38. J Biomol NMR 2005 0.93
69 Low-dose chest computed tomography for quantitative and visual anatomical analysis in patients with acute respiratory distress syndrome. Intensive Care Med 2014 0.92
70 Noninvasive carbon dioxide monitoring in a porcine model of acute lung injury due to smoke inhalation and burns. Shock 2013 0.91
71 Dynamic survey of mitochondria by ubiquitin. EMBO Rep 2014 0.90
72 The mitochondrial amidoxime-reducing component (mARC1) is a novel signal-anchored protein of the outer mitochondrial membrane. J Biol Chem 2012 0.89
73 A novel function for the 90 kDa heat-shock protein (Hsp90): facilitating nuclear export of 60 S ribosomal subunits. Biochem J 2002 0.89
74 Loss of prohibitin induces mitochondrial damages altering β-cell function and survival and is responsible for gradual diabetes development. Diabetes 2013 0.89
75 Familial Alzheimer's disease-associated presenilin-1 alters cerebellar activity and calcium homeostasis. J Clin Invest 2014 0.88
76 Reversible assembly of the ATP-binding cassette transporter Mdl1 with the F1F0-ATP synthase in mitochondria. J Biol Chem 2004 0.87
77 Targeting capacity and conservation of PreP homologues localization in mitochondria of different species. J Mol Biol 2011 0.85
78 The life of proteins: the good, the mostly good and the ugly. Nat Struct Mol Biol 2011 0.84
79 In vitro study of drug-eluting stent coatings based on poly(L-lactide) incorporating cyclosporine A - drug release, polymer degradation and mechanical integrity. J Mater Sci Mater Med 2007 0.84
80 [Quality indicators for National Disease Management Guidelines using the example of the National Disease Management Guideline for "Chronic Heart Failure"]. Z Evid Fortbild Qual Gesundhwes 2011 0.83
81 Loss of the m-AAA protease subunit AFG₃L₂ causes mitochondrial transport defects and tau hyperphosphorylation. EMBO J 2014 0.82
82 How psychological framing affects economic market prices in the lab and field. Proc Natl Acad Sci U S A 2013 0.81
83 Pseudotumor cerebri due to proximal haemodialysis fistula. Nephrol Dial Transplant 2006 0.81
84 Mitochondrial shaping cuts. Biochim Biophys Acta 2006 0.80
85 Low-dose CT for quantitative analysis in acute respiratory distress syndrome. Crit Care 2013 0.80
86 Mitochondrial lipid transport at a glance. J Cell Sci 2013 0.79
87 Microadenomas of the pituitary gland in children with and without hypophyseal dysfunction in magnetic resonance imaging. J Pediatr Endocrinol Metab 2002 0.79
88 StAR enhances transcription of genes encoding the mitochondrial proteases involved in its own degradation. Mol Endocrinol 2013 0.79
89 NMR backbone assignment of the N-terminal domain of human HSP90. J Biomol NMR 2006 0.79
90 Intravenous balanced solutions: from physiology to clinical evidence. Anaesthesiol Intensive Ther 2015 0.78
91 Distinct seasonal growth patterns of the bacterium Planktotalea frisia in the North Sea and specific interaction with phytoplankton algae. FEMS Microbiol Ecol 2013 0.78
92 [Sonographic findings in the diagnostic course of vascular access for hemodialysis]. Med Klin (Munich) 2005 0.78
93 Backbone NMR assignment of the low-molecular-weight protein tyrosine phosphatase (MPtpA) from Mycobacterium tuberculosis. J Biomol NMR 2005 0.77
94 Information service on new and emerging health technologies: identification and prioritization processes for a European union-wide newsletter. Int J Technol Assess Health Care 2009 0.77
95 Acute lung injury/acute respiratory distress syndrome pathophysiology: what we have learned from computed tomography scanning. Curr Opin Crit Care 2008 0.77
96 1,2-N-migration in a gold-catalysed synthesis of functionalised indenes by the 1,1-carboalkoxylation of ynamides. Chemistry 2014 0.77
97 1H, 13C and 15N backbone resonance assignment of the integrin alpha2 I-domain. J Biomol NMR 2003 0.77
98 Albumin in critically ill patients: the ideal colloid? Curr Opin Crit Care 2015 0.76
99 1H, 13C and 15N backbone resonance assignment of the peptidyl-prolyl cis-trans isomerase Pin1. J Biomol NMR 2002 0.76
100 Prone position ameliorates lung elastance and increases functional residual capacity independently from lung recruitment. Intensive Care Med Exp 2015 0.76
101 How much NMR data is required to determine a protein-ligand complex structure? Chembiochem 2005 0.76
102 Does peritoneal dialysis predispose a diabetic patient to icodextrin-induced peritonitis? Nephrol Dial Transplant 2002 0.75
103 Low-Dose Heparin Anticoagulation During Extracorporeal Life Support for Acute Respiratory Distress Syndrome in Conscious Sheep. Shock 2015 0.75
104 In reply. Dtsch Arztebl Int 2013 0.75
105 Electron Microscopy as a Tool for Assessment of Anticoagulation Strategies During Extracorporeal Life Support: The Proof Is on the Membrane. ASAIO J 2016 0.75
106 1H, 13C and 15N backbone resonance assignment of the Hsp90 binding domain of human Cdc37. J Biomol NMR 2005 0.75
107 Backbone NMR assignment of the human E2 ubiquitin conjugating enzyme UbcH5alpha (F72K,F82S) double mutant. J Biomol NMR 2005 0.75
108 [Diversity in spite of standards: the special features of NDGMs]. Z Evid Fortbild Qual Gesundhwes 2010 0.75
109 [Diagnostic imaging in oncology--evidence reviews for evidence based guidelines by the Agency of Quality for Medicine (ÄZQ)]. Z Evid Fortbild Qual Gesundhwes 2010 0.75
110 The seven wonders of ubiquitin: a multi-interview: Personal insights into the ubiquitin field. Interview by Nonia Pariente. EMBO Rep 2014 0.75
111 Highlight: The biology of aging: mechanisms and intervention. Biol Chem 2010 0.75
112 Backbone NMR assignment of the C-terminal haemopexin-like domain (HPLD) of human matrix metalloproteinase MMP-13. J Biomol NMR 2005 0.75