PubRank

Antonio Lanzavecchia

Author PubWeight™ 242.49‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Central memory and effector memory T cell subsets: function, generation, and maintenance. Annu Rev Immunol 2004 17.54
2 Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells. Nat Immunol 2007 13.70
3 Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells. Nat Immunol 2007 12.72
4 Maintenance of serological memory by polyclonal activation of human memory B cells. Science 2002 8.75
5 A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins. Science 2011 7.86
6 Development of a human adaptive immune system in cord blood cell-transplanted mice. Science 2004 7.07
7 Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells. Nat Immunol 2005 6.81
8 C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE. Nat Immunol 2009 5.97
9 Induced recruitment of NK cells to lymph nodes provides IFN-gamma for T(H)1 priming. Nat Immunol 2004 5.80
10 Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals. PLoS One 2010 5.73
11 An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus. Nat Med 2004 4.89
12 Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells. Nat Immunol 2009 4.69
13 Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming. J Exp Med 2003 4.64
14 Heterosubtypic neutralizing antibodies are produced by individuals immunized with a seasonal influenza vaccine. J Clin Invest 2010 4.62
15 Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β. Nature 2012 3.85
16 A role for Toll-like receptors in acquired immunity: up-regulation of TLR9 by BCR triggering in naive B cells and constitutive expression in memory B cells. Blood 2003 3.77
17 T cell fitness determined by signal strength. Nat Immunol 2003 3.65
18 Prophylactic and therapeutic efficacy of human monoclonal antibodies against H5N1 influenza. PLoS Med 2007 3.63
19 The dendritic cell-specific adhesion receptor DC-SIGN internalizes antigen for presentation to T cells. J Immunol 2002 3.48
20 The human immune response to Dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity. Cell Host Microbe 2010 3.48
21 From vaccines to memory and back. Immunity 2010 3.30
22 Coexpression of CD25 and CD27 identifies FoxP3+ regulatory T cells in inflamed synovia. J Exp Med 2005 3.29
23 Proliferation and differentiation potential of human CD8+ memory T-cell subsets in response to antigen or homeostatic cytokines. Blood 2003 3.23
24 Memory and flexibility of cytokine gene expression as separable properties of human T(H)1 and T(H)2 lymphocytes. Nat Immunol 2002 3.07
25 T cell costimulation by chemokine receptors. Nat Immunol 2005 3.00
26 Toll-like receptor stimulation as a third signal required for activation of human naive B cells. Eur J Immunol 2006 2.94
27 Broadly neutralizing antiviral antibodies. Annu Rev Immunol 2013 2.77
28 L-selectin-negative CCR7- effector and memory CD8+ T cells enter reactive lymph nodes and kill dendritic cells. Nat Immunol 2007 2.51
29 Antigenic fingerprinting of H5N1 avian influenza using convalescent sera and monoclonal antibodies reveals potential vaccine and diagnostic targets. PLoS Med 2009 2.47
30 Chemokine receptor expression identifies Pre-T helper (Th)1, Pre-Th2, and nonpolarized cells among human CD4+ central memory T cells. J Exp Med 2004 2.38
31 Persistent antigen and germinal center B cells sustain T follicular helper cell responses and phenotype. Immunity 2013 2.13
32 Immunogenetic mechanisms driving norovirus GII.4 antigenic variation. PLoS Pathog 2012 2.02
33 Functionally distinct subsets of human FOXP3+ Treg cells that phenotypically mirror effector Th cells. Blood 2012 2.00
34 Isolation of human monoclonal antibodies that potently neutralize human cytomegalovirus infection by targeting different epitopes on the gH/gL/UL128-131A complex. J Virol 2009 1.92
35 In-depth analysis of the antibody response of individuals exposed to primary dengue virus infection. PLoS Negl Trop Dis 2011 1.92
36 Heterogeneity of CD4+ memory T cells: functional modules for tailored immunity. Eur J Immunol 2009 1.92
37 Pivotal role of dendritic cell-derived CXCL10 in the retention of T helper cell 1 lymphocytes in secondary lymph nodes. J Exp Med 2002 1.91
38 Potent cross-reactive neutralization of SARS coronavirus isolates by human monoclonal antibodies. Proc Natl Acad Sci U S A 2007 1.76
39 Activation of the Flt3 signal transduction cascade rescues and enhances type I interferon-producing and dendritic cell development. J Exp Med 2006 1.75
40 Evasion of antibody neutralization in emerging severe acute respiratory syndrome coronaviruses. Proc Natl Acad Sci U S A 2005 1.75
41 Clonal dissection of the human memory B-cell repertoire following infection and vaccination. Eur J Immunol 2009 1.74
42 Human anti-HIV-neutralizing antibodies frequently target a conserved epitope essential for viral fitness. J Exp Med 2010 1.74
43 Cross-neutralization of four paramyxoviruses by a human monoclonal antibody. Nature 2013 1.73
44 Human naive and memory CD4+ T cell repertoires specific for naturally processed antigens analyzed using libraries of amplified T cells. J Exp Med 2009 1.71
45 ABCB1 transporter discriminates human resting naive B cells from cycling transitional and memory B cells. Eur J Immunol 2005 1.68
46 Duration, combination and timing: the signal integration model of dendritic cell activation. Trends Immunol 2007 1.55
47 Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA. Mol Microbiol 2006 1.48
48 Emergence of new pandemic GII.4 Sydney norovirus strain correlates with escape from herd immunity. J Infect Dis 2013 1.47
49 Division of labor with a workforce of one: challenges in specifying effector and memory T cell fate. Science 2007 1.47
50 Human Th17 subsets. Eur J Immunol 2012 1.46
51 Crystal structure and size-dependent neutralization properties of HK20, a human monoclonal antibody binding to the highly conserved heptad repeat 1 of gp41. PLoS Pathog 2010 1.36
52 Prostaglandin E2 enhances Th17 responses via modulation of IL-17 and IFN-gamma production by memory CD4+ T cells. Eur J Immunol 2009 1.34
53 Kinetics and expression patterns of chemokine receptors in human CD4+ T lymphocytes primed by myeloid or plasmacytoid dendritic cells. Eur J Immunol 2003 1.29
54 Antigen dependent and independent mechanisms that sustain serum antibody levels. Vaccine 2003 1.27
55 Human Th17 cells in infection and autoimmunity. Microbes Infect 2009 1.26
56 The instructive role of dendritic cells on T-cell responses. Arthritis Res 2002 1.26
57 Pemphigus autoantibodies generated through somatic mutations target the desmoglein-3 cis-interface. J Clin Invest 2012 1.25
58 An anti-HIV-1 V3 loop antibody fully protects cross-clade and elicits T-cell immunity in macaques mucosally challenged with an R5 clade C SHIV. PLoS One 2011 1.24
59 Dendritic cell-derived IL-2 production is regulated by IL-15 in humans and in mice. Blood 2004 1.24
60 Structural basis for potent cross-neutralizing human monoclonal antibody protection against lethal human and zoonotic severe acute respiratory syndrome coronavirus challenge. J Virol 2008 1.22
61 Therapeutic efficacy of antibodies lacking Fcγ receptor binding against lethal dengue virus infection is due to neutralizing potency and blocking of enhancing antibodies [corrected]. PLoS Pathog 2013 1.20
62 Fetal human cytomegalovirus transmission correlates with delayed maternal antibodies to gH/gL/pUL128-130-131 complex during primary infection. PLoS One 2013 1.19
63 Improved innate and adaptive immunostimulation by genetically modified HIV-1 protein expressing NYVAC vectors. PLoS One 2011 1.16
64 T-cell trafficking in the central nervous system. Immunol Rev 2012 1.15
65 T cell priming by dendritic cells: thresholds for proliferation, differentiation and death and intraclonal functional diversification. Eur J Immunol 2002 1.14
66 CD40L+ CD4+ memory T cells migrate in a CD62P-dependent fashion into reactive lymph nodes and license dendritic cells for T cell priming. J Exp Med 2008 1.14
67 Dissecting the human immunologic memory for pathogens. Immunol Rev 2011 1.12
68 Activation of src-family tyrosine kinases by LPS regulates cytokine production in dendritic cells by controlling AP-1 formation. Eur J Immunol 2003 1.12
69 A temporal and spatial summation model for T-cell activation: signal integration and antigen decoding. Trends Immunol 2002 1.11
70 Human adaptive immune system Rag2-/-gamma(c)-/- mice. Ann N Y Acad Sci 2005 1.10
71 Chondroitin sulfate A-adhering Plasmodium falciparum-infected erythrocytes express functionally important antibody epitopes shared by multiple variants. J Immunol 2010 1.08
72 The Neonatal Fc receptor (FcRn) enhances human immunodeficiency virus type 1 (HIV-1) transcytosis across epithelial cells. PLoS Pathog 2013 1.07
73 Escape from human monoclonal antibody neutralization affects in vitro and in vivo fitness of severe acute respiratory syndrome coronavirus. J Infect Dis 2010 1.07
74 A cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation required for cytokine expression. J Exp Med 2006 1.06
75 Immune subversion by Helicobacter pylori. Trends Immunol 2005 1.06
76 Dendritic cell migration to peripheral lymph nodes. Handb Exp Pharmacol 2009 1.04
77 CCR6 is expressed on an IL-10-producing, autoreactive memory T cell population with context-dependent regulatory function. J Exp Med 2010 1.03
78 Antibodies against neutralization epitopes of human cytomegalovirus gH/gL/pUL128-130-131 complex and virus spreading may correlate with virus control in vivo. J Clin Immunol 2012 1.02
79 Pillars article: two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature. 1999. 401: 708-712. J Immunol 2014 0.98
80 Fourteenth Annual Pezcoller Symposium: the novel dichotomy of immune interactions with tumors. Cancer Res 2003 0.97
81 CD34+ cord blood cell-transplanted Rag2-/- gamma(c)-/- mice as a model for Epstein-Barr virus infection. Am J Pathol 2008 0.95
82 The strength of T cell stimulation determines IL-7 responsiveness, secondary expansion, and lineage commitment of primed human CD4+IL-7Rhi T cells. Eur J Immunol 2008 0.94
83 Strain-transcending Fc-dependent killing of Plasmodium falciparum by merozoite surface protein 2 allele-specific human antibodies. Infect Immun 2010 0.93
84 Monocytes join the dendritic cell family. Cell 2010 0.93
85 Simvastatin inhibits the MHC class II pathway of antigen presentation by impairing Ras superfamily GTPases. Eur J Immunol 2006 0.92
86 TCR-independent proliferation and differentiation of human CD4+ T cell subsets induced by cytokines. Adv Exp Med Biol 2002 0.90
87 Lead and follow: the dance of the dendritic cell and T cell. Nat Immunol 2004 0.90
88 Characterization of severe acute respiratory syndrome coronavirus membrane protein. FEBS Lett 2006 0.89
89 Lack of fair play in the T cell response. Nat Immunol 2002 0.89
90 Regulation of peripheral T cell activation by calreticulin. J Exp Med 2006 0.89
91 Memory in disguise. Nat Med 2011 0.89
92 Studies on membrane topology, N-glycosylation and functionality of SARS-CoV membrane protein. Virol J 2009 0.87
93 Systems analysis of MVA-C induced immune response reveals its significance as a vaccine candidate against HIV/AIDS of clade C. PLoS One 2012 0.87
94 A functional BCR in human IgA and IgM plasma cells. Blood 2013 0.83
95 CD4+ CD25+ Treg regulate the contribution of CD8+ T-cell subsets in repopulation of the lymphopenic environment. Eur J Immunol 2010 0.83
96 Characterization of neutralizing profiles in HIV-1 infected patients from whom the HJ16, HGN194 and HK20 mAbs were obtained. PLoS One 2011 0.83
97 Rational engineering of a human anti-dengue antibody through experimentally validated computational docking. PLoS One 2013 0.82
98 Infections and organ transplantation: new challenges for prevention and treatment--a colloquium. Transplantation 2012 0.82
99 Cdk9/Cyclin T1 complex: a key player during the activation/differentiation process of normal lymphoid B cells. J Cell Physiol 2008 0.80
100 High throughput cellular screens to interrogate the human T and B cell repertoires. Curr Opin Immunol 2011 0.80
101 Efficient Methods To Isolate Human Monoclonal Antibodies from Memory B Cells and Plasma Cells. Microbiol Spectr 2014 0.79
102 Optimizing anti-CD3 affinity for effective T cell targeting against tumor cells. Eur J Immunol 2002 0.79
103 Pillars article: Antigen-specific interaction between T and B cells. 1985. J Immunol 2007 0.76
104 Corrigendum: A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence. Nat Med 2016 0.75
105 Current Opinion in Immunology. Vaccines. Introduction. Curr Opin Immunol 2010 0.75