Effect of an FTO polymorphism on fat mass, obesity, and type 2 diabetes mellitus in the French MONICA Study.

PubWeight™: 1.05‹?› | Rank: Top 15%

🔗 View Article (PMID 19375760)

Published in Metabolism on July 01, 2009

Authors

Vanessa Legry1, Dominique Cottel, Jean Ferrières, Dominique Arveiler, Nicolas Andrieux, Annie Bingham, Aline Wagner, Jean-Bernard Ruidavets, Pierre Ducimetière, Philippe Amouyel, Aline Meirhaeghe

Author Affiliations

1: INSERM, U744, Lille, France.

Articles citing this

FTO gene polymorphisms and obesity risk: a meta-analysis. BMC Med (2011) 1.34

An FTO variant is associated with Type 2 diabetes in South Asian populations after accounting for body mass index and waist circumference. Diabet Med (2011) 1.23

A high intake of saturated fatty acids strengthens the association between the fat mass and obesity-associated gene and BMI. J Nutr (2011) 1.20

FTO is increased in muscle during type 2 diabetes, and its overexpression in myotubes alters insulin signaling, enhances lipogenesis and ROS production, and induces mitochondrial dysfunction. Diabetes (2010) 1.13

Identification of genes and networks driving cardiovascular and metabolic phenotypes in a mouse F2 intercross. PLoS One (2010) 1.04

Associations of the FTO rs9939609 and the MC4R rs17782313 polymorphisms with type 2 diabetes are modulated by diet, being higher when adherence to the Mediterranean diet pattern is low. Cardiovasc Diabetol (2012) 1.03

Milk: an epigenetic amplifier of FTO-mediated transcription? Implications for Western diseases. J Transl Med (2015) 0.85

FTO Gene Variants Are Associated with PCOS Susceptibility and Hyperandrogenemia in Young Korean Women. Diabetes Metab J (2014) 0.84

Interactions between the FTO rs9939609 polymorphism, body mass index, and lifestyle-related factors on metabolic syndrome risk. Nutr Res Pract (2012) 0.82

Associations of genetic variants in/near body mass index-associated genes with type 2 diabetes: a systematic meta-analysis. Clin Endocrinol (Oxf) (2014) 0.81

FTO is a relevant factor for the development of the metabolic syndrome in mice. PLoS One (2014) 0.79

FTO Biology and Obesity: Why Do a Billion of Us Weigh 3 kg More? Front Endocrinol (Lausanne) (2011) 0.77

Effect of the Common Fat Mass and Obesity Associated Gene Variants on Obesity in Pakistani Population: A Case-Control Study. Biomed Res Int (2015) 0.77

Association of SNP rs9939609 in FTO gene with metabolic syndrome in type 2 diabetic subjects, rectruited from a tertiary care unit of Karachi, Pakistan. Pak J Med Sci (2015) 0.77

Correlation between polymorphism of FTO gene and type 2 diabetes mellitus in Uygur people from northwest China. Int J Clin Exp Med (2015) 0.76

FTO Genotype and Type 2 Diabetes Mellitus: Spatial Analysis and Meta-Analysis of 62 Case-Control Studies from Different Regions. Genes (Basel) (2017) 0.75

Articles by these authors

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. Nat Genet (2009) 14.86

Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes (2007) 14.12

TREM2 variants in Alzheimer's disease. N Engl J Med (2012) 11.35

Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA (2010) 9.52

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet (2011) 9.23

Genetic determinants of response to clopidogrel and cardiovascular events. N Engl J Med (2008) 8.39

Alpha-synuclein locus duplication as a cause of familial Parkinson's disease. Lancet (2004) 7.69

Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet (2012) 7.59

C-reactive protein, fibrinogen, and cardiovascular disease prediction. N Engl J Med (2012) 6.39

Heart-rate profile during exercise as a predictor of sudden death. N Engl J Med (2005) 4.85

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet (2012) 4.63

Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease. Nat Genet (2009) 4.63

Fruit and vegetable consumption and risk of coronary heart disease: a meta-analysis of cohort studies. J Nutr (2006) 4.63

Lipid treatment assessment project 2: a multinational survey to evaluate the proportion of patients achieving low-density lipoprotein cholesterol goals. Circulation (2009) 3.98

Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children. PLoS Med (2011) 3.94

Downward trends in the prevalence of childhood overweight in the setting of 12-year school- and community-based programmes. Public Health Nutr (2008) 3.53

Relationship between blood pressure and outdoor temperature in a large sample of elderly individuals: the Three-City study. Arch Intern Med (2009) 3.38

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25

Patterns of alcohol consumption and ischaemic heart disease in culturally divergent countries: the Prospective Epidemiological Study of Myocardial Infarction (PRIME). BMJ (2010) 2.97

Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet (2013) 2.92

Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance. PLoS Biol (2006) 2.86

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet (2013) 2.83

Slow walking speed and cardiovascular death in well functioning older adults: prospective cohort study. BMJ (2009) 2.62

A genome-wide association meta-analysis identifies new childhood obesity loci. Nat Genet (2012) 2.60

A polymorphism in CALHM1 influences Ca2+ homeostasis, Abeta levels, and Alzheimer's disease risk. Cell (2008) 2.55

Risk factors for coronary heart disease in patients treated for human immunodeficiency virus infection compared with the general population. Clin Infect Dis (2003) 2.54

Clinical events as a function of proton pump inhibitor use, clopidogrel use, and cytochrome P450 2C19 genotype in a large nationwide cohort of acute myocardial infarction: results from the French Registry of Acute ST-Elevation and Non-ST-Elevation Myocardial Infarction (FAST-MI) registry. Circulation (2011) 2.47

Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium. Ann Neurol (2011) 2.37

Comparison of thrombolysis followed by broad use of percutaneous coronary intervention with primary percutaneous coronary intervention for ST-segment-elevation acute myocardial infarction: data from the french registry on acute ST-elevation myocardial infarction (FAST-MI). Circulation (2008) 2.33

Predicting diabetes: clinical, biological, and genetic approaches: data from the Epidemiological Study on the Insulin Resistance Syndrome (DESIR). Diabetes Care (2008) 2.32

Interleukin-18 and the risk of coronary heart disease in European men: the Prospective Epidemiological Study of Myocardial Infarction (PRIME). Circulation (2003) 2.26

Five-year survival in patients with ST-segment-elevation myocardial infarction according to modalities of reperfusion therapy: the French Registry on Acute ST-Elevation and Non-ST-Elevation Myocardial Infarction (FAST-MI) 2005 Cohort. Circulation (2014) 2.21

Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's disease in the European population. Hum Mol Genet (2010) 2.21

Fruit and vegetable consumption and risk of stroke: a meta-analysis of cohort studies. Neurology (2005) 2.12

Relation of heart rate at rest and long-term (>20 years) death rate in initially healthy middle-aged men. Am J Cardiol (2008) 2.03

CYP2D6 polymorphism, pesticide exposure, and Parkinson's disease. Ann Neurol (2004) 2.03

Circulating soluble adhesion molecules ICAM-1 and VCAM-1 and incident coronary heart disease: the PRIME Study. Atherosclerosis (2003) 2.02

C-reactive protein, interleukin-6, and fibrinogen as predictors of coronary heart disease: the PRIME Study. Arterioscler Thromb Vasc Biol (2003) 1.99

The Three-Factor Eating Questionnaire-R18 is able to distinguish among different eating patterns in a general population. J Nutr (2004) 1.95

Increased risk of myocardial infarction in HIV-infected patients in France, relative to the general population. AIDS (2010) 1.93

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. Nat Genet (2012) 1.90

Relationship between blood pressure and depression in the elderly. The Three-City Study. J Hypertens (2008) 1.79

Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nat Genet (2012) 1.79

Genome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosis. PLoS Genet (2011) 1.77

Does personality explain social inequalities in mortality? The French GAZEL cohort study. Int J Epidemiol (2008) 1.73

Postnatal weight and height growth velocities at different ages between birth and 5 y and body composition in adolescent boys and girls. Am J Clin Nutr (2008) 1.72

Ozone air pollution is associated with acute myocardial infarction. Circulation (2005) 1.71

Environmental factors associated with body mass index in a population of Southern France. Eur J Cardiovasc Prev Rehabil (2004) 1.70

The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis. PLoS Med (2013) 1.70

Contribution of novel biomarkers to incident stable angina and acute coronary syndrome: the PRIME Study. Eur Heart J (2008) 1.68

Polymorphisms of the beta2 -adrenoceptor (ADRB2) gene and essential hypertension: the ECTIM and PEGASE studies. J Hypertens (2002) 1.68

Polymorphisms in the promoter regions of MMP-2, MMP-3, MMP-9 and MMP-12 genes as determinants of aneurysmal coronary artery disease. J Am Coll Cardiol (2002) 1.66

Implication of the immune system in Alzheimer's disease: evidence from genome-wide pathway analysis. J Alzheimers Dis (2010) 1.65

A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease. Circ Cardiovasc Genet (2011) 1.63

Excessive heart rate increase during mild mental stress in preparation for exercise predicts sudden death in the general population. Eur Heart J (2009) 1.61

Household income is associated with the risk of metabolic syndrome in a sex-specific manner. Diabetes Care (2005) 1.59

Prognostic impact of matrix metalloproteinase gene polymorphisms in patients with heart failure according to the aetiology of left ventricular systolic dysfunction. Eur Heart J (2004) 1.59

Fish consumption is associated with lower heart rates. Circulation (2003) 1.56

Independent contribution of dairy products and calcium intake to blood pressure variations at a population level. J Hypertens (2006) 1.56