Mechanism of growth inhibition by MicroRNA 145: the role of the IGF-I receptor signaling pathway.

PubWeight™: 1.45‹?› | Rank: Top 5%

🔗 View Article (PMID 19391107)

Published in J Cell Physiol on August 01, 2009

Authors

Gaspare La Rocca1, Margherita Badin, Bin Shi, Shi-Qiong Xu, Tiziana Deangelis, Laura Sepp-Lorenzinoi, Renato Baserga

Author Affiliations

1: Department of Cancer Biology at Thomas Jefferson University, Kimmel Cancer Center, Philadelphia, PA 19107, USA.

Articles citing this

MicroRNAs in colorectal cancer: translation of molecular biology into clinical application. Mol Cancer (2009) 2.45

MicroRNA-145 targets YES and STAT1 in colon cancer cells. PLoS One (2010) 1.64

MicroRNA-497 targets insulin-like growth factor 1 receptor and has a tumour suppressive role in human colorectal cancer. Oncogene (2012) 1.63

Epigenetics of colorectal cancer. Gastroenterology (2012) 1.60

Differential expression of miRNAs in colorectal cancer: comparison of paired tumor tissue and adjacent normal mucosa using high-throughput sequencing. PLoS One (2012) 1.58

Mirna expression profiles identify drivers in colorectal and pancreatic cancers. PLoS One (2012) 1.47

Expression and function of the insulin receptor substrate proteins in cancer. Cell Commun Signal (2009) 1.35

Putative tumor suppressor miR-145 inhibits colon cancer cell growth by targeting oncogene Friend leukemia virus integration 1 gene. Cancer (2010) 1.34

miR-145-mediated suppression of cell growth, invasion and metastasis. Am J Transl Res (2010) 1.29

miR-143 and miR-145 are downregulated in ulcerative colitis: putative regulators of inflammation and protooncogenes. Inflamm Bowel Dis (2011) 1.20

MicroRNA-143 inhibits tumor growth and angiogenesis and sensitizes chemosensitivity to oxaliplatin in colorectal cancers. Cell Cycle (2013) 1.16

Differential expression of microRNAs in tumors from chronically inflamed or genetic (APC(Min/+)) models of colon cancer. PLoS One (2011) 1.16

MicroRNA-145 is downregulated in glial tumors and regulates glioma cell migration by targeting connective tissue growth factor. PLoS One (2013) 1.15

Recent insights into the pathogenesis of colorectal cancer. Curr Opin Gastroenterol (2010) 1.13

Silencing of a large microRNA cluster on human chromosome 14q32 in melanoma: biological effects of mir-376a and mir-376c on insulin growth factor 1 receptor. Mol Cancer (2012) 1.12

miR-21 and miR-214 are consistently modulated during renal injury in rodent models. Am J Pathol (2011) 1.10

MicroRNA-221 inhibits CDKN1C/p57 expression in human colorectal carcinoma. Acta Pharmacol Sin (2011) 1.08

MicroRNA-145: a potent tumour suppressor that regulates multiple cellular pathways. J Cell Mol Med (2014) 1.08

Minireview: posttranscriptional regulation of the insulin and insulin-like growth factor systems. Endocrinology (2009) 1.05

microRNAs and lung cancer: tumors and 22-mers. Cancer Metastasis Rev (2010) 1.01

Retracted MiR-145 regulates epithelial to mesenchymal transition of breast cancer cells by targeting Oct4. PLoS One (2012) 1.00

MiR-143 and MiR-145 regulate IGF1R to suppress cell proliferation in colorectal cancer. PLoS One (2014) 0.99

Heme levels are increased in human failing hearts. J Am Coll Cardiol (2013) 0.98

Implications of miR cluster 143/145 as universal anti-oncomiRs and their dysregulation during tumorigenesis. Cancer Cell Int (2015) 0.96

Exploring and exploiting the fundamental role of microRNAs in tumor pathogenesis. Onco Targets Ther (2013) 0.96

Reciprocal regulation of microRNA-99a and insulin-like growth factor I receptor signaling in oral squamous cell carcinoma cells. Mol Cancer (2014) 0.93

The Akt-associated microRNAs. Cell Mol Life Sci (2012) 0.91

Implications of microRNAs in colorectal cancer development, diagnosis, prognosis, and therapeutics. Front Genet (2011) 0.88

MicroRNA-126 suppresses mesothelioma malignancy by targeting IRS1 and interfering with the mitochondrial function. Antioxid Redox Signal (2014) 0.86

The Insulin/IGF System in Colorectal Cancer Development and Resistance to Therapy. Front Oncol (2015) 0.85

An integrative analysis of cellular contexts, miRNAs and mRNAs reveals network clusters associated with antiestrogen-resistant breast cancer cells. BMC Genomics (2012) 0.84

Role of miR-100 in the radioresistance of colorectal cancer cells. Am J Cancer Res (2015) 0.84

MicroRNA Profiling Response to Acupuncture Therapy in Spontaneously Hypertensive Rats. Evid Based Complement Alternat Med (2015) 0.83

MicroRNAs induced in melanoma treated with combination targeted therapy of Temsirolimus and Bevacizumab. J Transl Med (2013) 0.83

miRNAs as biomarkers for management of patients with colorectal cancer. Biomark Med (2010) 0.83

The potential value of miR-1 and miR-374b as biomarkers for colorectal cancer. Int J Clin Exp Pathol (2015) 0.82

MicroRNA-145 inhibits migration and invasion by down-regulating FSCN1 in lung cancer. Int J Clin Exp Med (2015) 0.82

An integrated analysis of miRNA and gene copy numbers in xenografts of Ewing's sarcoma. J Exp Clin Cancer Res (2012) 0.81

Investigating microRNA-target interaction-supported tissues in human cancer tissues based on miRNA and target gene expression profiling. PLoS One (2014) 0.81

Posttranscriptional regulation of insulin family ligands and receptors. Int J Mol Sci (2013) 0.79

TGFβ/Smad3 regulates proliferation and apoptosis through IRS-1 inhibition in colon cancer cells. PLoS One (2017) 0.78

Role of Akt2 in regulation of metastasis suppressor 1 expression and colorectal cancer metastasis. Oncogene (2017) 0.76

MicroRNA regulation of mitogenic signaling networks in the human placenta. J Biol Chem (2014) 0.75

Intravesical treatment of advanced urothelial bladder cancers with oncolytic HSV-1 co-regulated by differentially expressed microRNAs. Gene Ther (2016) 0.75

Articles by these authors

Micro RNA 145 targets the insulin receptor substrate-1 and inhibits the growth of colon cancer cells. J Biol Chem (2007) 2.55

CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cells. Nat Cell Biol (2010) 2.36

Control of basement membrane remodeling and epithelial branching morphogenesis in embryonic lung by Rho and cytoskeletal tension. Dev Dyn (2005) 2.13

14-3-3zeta Cooperates with ErbB2 to promote ductal carcinoma in situ progression to invasive breast cancer by inducing epithelial-mesenchymal transition. Cancer Cell (2009) 2.09

Porphyromonas gingivalis may play an important role in the pathogenesis of periodontitis-associated rheumatoid arthritis. Med Hypotheses (2009) 1.97

Hypomethylation-linked activation of PAX2 mediates tamoxifen-stimulated endometrial carcinogenesis. Nature (2005) 1.86

In vivo tumor targeting of tumor necrosis factor-alpha-loaded stealth nanoparticles: effect of MePEG molecular weight and particle size. Eur J Pharm Sci (2005) 1.72

Self-expanding metallic stent as a bridge to surgery versus emergency surgery for obstructive colorectal cancer: a meta-analysis. Surg Endosc (2011) 1.65

Adiponectin suppression of high-glucose-induced reactive oxygen species in vascular endothelial cells: evidence for involvement of a cAMP signaling pathway. Diabetes (2006) 1.56

Growth inhibition by microRNAs that target the insulin receptor substrate-1. Cell Cycle (2009) 1.49

Molecular mechanisms involved in the growth stimulation of breast cancer cells by leptin. Cancer Res (2004) 1.47

Expression of chemokine CXCL12 and its receptor CXCR4 in human epithelial ovarian cancer: an independent prognostic factor for tumor progression. Gynecol Oncol (2006) 1.46

Coordinated regulation of AIB1 transcriptional activity by sumoylation and phosphorylation. J Biol Chem (2006) 1.43

Differential gene regulation by the SRC family of coactivators. Genes Dev (2004) 1.41

Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylation negatively modulates EGFR-mediated ERK activation. Nat Cell Biol (2011) 1.40

AMG 479, a fully human anti-insulin-like growth factor receptor type I monoclonal antibody, inhibits the growth and survival of pancreatic carcinoma cells. Mol Cancer Ther (2009) 1.39

Retracted New proposal for the serum ascites albumin gradient cut-off value in Chinese ascitic patients. Diagn Pathol (2013) 1.37

Endothelial-directed hepatic regeneration after partial hepatectomy. Ann Surg (2003) 1.34

microRNA, cell cycle, and human breast cancer. Am J Pathol (2010) 1.32

TOR signaling is a determinant of cell survival in response to DNA damage. Mol Cell Biol (2007) 1.28

The microRNA miR-92 increases proliferation of myeloid cells and by targeting p63 modulates the abundance of its isoforms. FASEB J (2009) 1.23

Decorin antagonizes IGF receptor I (IGF-IR) function by interfering with IGF-IR activity and attenuating downstream signaling. J Biol Chem (2011) 1.21

Nutrient restriction and radiation therapy for cancer treatment: when less is more. Oncologist (2013) 1.20

Adiponectin suppresses IkappaB kinase activation induced by tumor necrosis factor-alpha or high glucose in endothelial cells: role of cAMP and AMP kinase signaling. Am J Physiol Endocrinol Metab (2007) 1.15

The insulin-like growth factor receptor I promotes motility and invasion of bladder cancer cells through Akt- and mitogen-activated protein kinase-dependent activation of paxillin. Am J Pathol (2010) 1.13

Proepithelin regulates prostate cancer cell biology by promoting cell growth, migration, and anchorage-independent growth. Am J Pathol (2009) 1.08

Control of cell size through phosphorylation of upstream binding factor 1 by nuclear phosphatidylinositol 3-kinase. Proc Natl Acad Sci U S A (2004) 1.08

Functional significance of type 1 insulin-like growth factor-mediated nuclear translocation of the insulin receptor substrate-1 and beta-catenin. J Biol Chem (2005) 1.08

Nuclear translocation of insulin receptor substrate-1 by oncogenes and Igf-I. Effect on ribosomal RNA synthesis. J Biol Chem (2002) 1.07

Insulin-like growth factor I receptor signaling and nuclear translocation of insulin receptor substrates 1 and 2. Mol Endocrinol (2002) 1.05

Signaling differences from the A and B isoforms of the insulin receptor (IR) in 32D cells in the presence or absence of IR substrate-1. Endocrinology (2003) 1.01

Delivery of PDGF-B and BMP-7 by mesoporous bioglass/silk fibrin scaffolds for the repair of osteoporotic defects. Biomaterials (2012) 1.00

Nuclear translocation of insulin receptor substrate-1 by the simian virus 40 T antigen and the activated type 1 insulin-like growth factor receptor. J Biol Chem (2002) 0.98

A modified tandem affinity purification tag technique for the purification of protein complexes in mammalian cells. Proteomics (2005) 0.98

Proepithelin is an autocrine growth factor for bladder cancer. Carcinogenesis (2009) 0.97

Enhanced bone regeneration around dental implant with bone morphogenetic protein 2 gene and vascular endothelial growth factor protein delivery. Clin Oral Implants Res (2011) 0.96

PARP-1 Val762Ala polymorphism, CagA+ H. pylori infection and risk for gastric cancer in Han Chinese population. Mol Biol Rep (2008) 0.95

Severe intraoperative complications during VATS Lobectomy compared with thoracotomy lobectomy for early stage non-small cell lung cancer. J Thorac Dis (2013) 0.95

Anabolic bone formation via a site-specific bone-targeting delivery system by interfering with semaphorin 4D expression. J Bone Miner Res (2015) 0.94

Role of pescadillo in the transformation and immortalization of mammalian cells. Oncogene (2004) 0.92

Tamoxifen and toremifene cause impairment of learning and memory function in mice. Pharmacol Biochem Behav (2002) 0.92

Over-accumulation of nuclear IGF-1 receptor in tumor cells requires elevated expression of the receptor and the SUMO-conjugating enzyme Ubc9. Biochem Biophys Res Commun (2010) 0.92

Design and synthesis of 3,7-diarylimidazopyridines as inhibitors of the VEGF-receptor KDR. Bioorg Med Chem Lett (2004) 0.91

Role of pescadillo and upstream binding factor in the proliferation and differentiation of murine myeloid cells. Mol Cell Biol (2004) 0.91

Novel anti-tumor strategy: PEG-hydroxycamptothecin conjugate loaded transferrin-PEG-nanoparticles. J Control Release (2009) 0.90

The role of insulin receptor substrate-1 in transformation by v-src. J Cell Physiol (2008) 0.90

A novel bioactive three-dimensional beta-tricalcium phosphate/chitosan scaffold for periodontal tissue engineering. J Mater Sci Mater Med (2009) 0.90

Insulin receptor substrate-1 regulates the transformed phenotype of BT-20 human mammary cancer cells. Cancer Res (2007) 0.89

Intracellular redistribution of nuclear and nucleolar proteins during differentiation of 32D murine hemopoietic cells. Exp Cell Res (2003) 0.89

Combination of scaffold and adenovirus vectors expressing bone morphogenetic protein-7 for alveolar bone regeneration at dental implant defects. Biomaterials (2007) 0.88

Nuclear translocation of insulin receptor substrate-1 by the insulin receptor in mouse embryo fibroblasts. J Cell Physiol (2003) 0.88

Targeting the IGF-1 receptor: from rags to riches. Eur J Cancer (2004) 0.88

Comparative analysis of human and mouse immunoglobulin variable heavy regions from IMGT/LIGM-DB with IMGT/HighV-QUEST. Theor Biol Med Model (2014) 0.87

MicroRNA 96 is a post-transcriptional suppressor of anaplastic lymphoma kinase expression. Am J Pathol (2012) 0.87

Identification of biomarkers for tumor endothelial cell proliferation through gene expression profiling. Mol Cancer Ther (2005) 0.87

Novel gene-activated matrix with embedded chitosan/plasmid DNA nanoparticles encoding PDGF for periodontal tissue engineering. J Biomed Mater Res A (2009) 0.86

COX-2 inhibition improves immune system homeostasis and decreases liver damage in septic rats. J Surg Res (2009) 0.86

Porous CaP/silk composite scaffolds to repair femur defects in an osteoporotic model. J Mater Sci Mater Med (2013) 0.86

Enhancing the bioavailability of cyclosporine a using solid dispersion containing polyoxyethylene (40) stearate. Drug Dev Ind Pharm (2006) 0.86

Failure rates of short (≤ 10 mm) dental implants and factors influencing their failure: a systematic review. Int J Oral Maxillofac Implants (2011) 0.86

Novel chitosan/collagen scaffold containing transforming growth factor-beta1 DNA for periodontal tissue engineering. Biochem Biophys Res Commun (2006) 0.86

The applications of corrected standardized uptake values in the diagnosis of peripheral lung lesions. Medicine (Baltimore) (2015) 0.86

Expression of insulin-like growth factor-1 receptor in metastatic uveal melanoma and implications for potential autocrine and paracrine tumor cell growth. Pigment Cell Melanoma Res (2014) 0.85

Hepatitis B virus DNA in patients with hepatitis B-related liver cirrhosis with or without hepatocellular carcinomas: a matched case-control study. J Dig Dis (2009) 0.85

Inhibition of the single downstream target BAG1 activates the latent apoptotic potential of MYC. Mol Cell Biol (2011) 0.85

Regulation of upstream binding factor 1 activity by insulin-like growth factor I receptor signaling. J Biol Chem (2004) 0.85

Three-dimensional nanohydroxyapatite/chitosan scaffolds as potential tissue engineered periodontal tissue. J Biomater Appl (2006) 0.84

Regulation of Id1 protein expression in mouse embryo fibroblasts by the type 1 insulin-like growth factor receptor. Exp Cell Res (2002) 0.84

Tamoxifen and toremifene impair retrieval, but not acquisition, of spatial information processing in mice. Pharmacol Biochem Behav (2002) 0.84

IGF1 receptor expression protects against microenvironmental stress found in the solid tumor. Radiat Res (2002) 0.84

Regulation of microRNA-145 by growth arrest and differentiation. Exp Cell Res (2010) 0.84

Expression of micro-RNA-145 is regulated by a highly conserved genomic sequence 3' to the pre-miR. J Cell Physiol (2011) 0.84

Regulation of insulin receptor substrate-1 expression levels by caveolin-1. J Cell Physiol (2008) 0.84

Roles of bone scintigraphy and resonance frequency analysis in evaluating osseointegration of endosseous implant. Biomaterials (2007) 0.84

Proline-rich tyrosine kinase 2 (Pyk2) regulates IGF-I-induced cell motility and invasion of urothelial carcinoma cells. PLoS One (2012) 0.83

The type 1 insulin-like growth factor receptor and resistance to DACH1. Cell Cycle (2011) 0.83

Mutations in the EDA gene are responsible for X-linked hypohidrotic ectodermal dysplasia and hypodontia in Chinese kindreds. Eur J Oral Sci (2008) 0.83

A platelet-derived growth factor releasing chitosan/coral composite scaffold for periodontal tissue engineering. Biomaterials (2006) 0.82

[Influence of particle size and MePEG molecular weight on in vitro macrophage uptake and in vivo long circulating of stealth nanoparticles in rats]. Yao Xue Xue Bao (2006) 0.82

A mechanism for cell size regulation by the insulin and insulin-like growth factor-I receptors. Cancer Res (2006) 0.81

Downregulation of the upstream binding factor1 by glycogen synthase kinase3beta in myeloid cells induced to differentiate. J Cell Biochem (2007) 0.81

24p3 in differentiation of myeloid cells. J Cell Physiol (2005) 0.81

Deletion of the pleckstrin and phosphotyrosine binding domains of insulin receptor substrate-2 does not impair its ability to regulate cell proliferation in myeloid cells. Endocrinology (2004) 0.81

Prognostic power of abnormal cytogenetics for multiple myeloma: a multicenter study in China. Chin Med J (Engl) (2012) 0.81

Personalized Reconstruction of Traumatic Orbital Defects Based on Precise Three-Dimensional Orientation and Measurements of the Globe. J Craniofac Surg (2016) 0.81

[An experimental study on anterior cruciate ligament reconstruction with remnants and remaining bundle preservation]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi (2009) 0.80

Mutual interaction and reciprocal down-regulation between c-met and insulin receptor substrate-1. J Cell Physiol (2010) 0.80

Active tumor-targeted delivery of PEG-protein via transferrin-transferrin-receptor system. J Drug Target (2007) 0.80

Expression profiles of micro RNA in proliferating and differentiating 32D murine myeloid cells. J Cell Physiol (2006) 0.80

Confirmation and prevention of intestinal barrier dysfunction and bacterial translocation caused by methotrexate. Dig Dis Sci (2006) 0.80

Hypoxia-inducible factor-1α polymorphisms and risk of cancer metastasis: a meta-analysis. PLoS One (2013) 0.80

Novel and convenient method to evaluate the character of solitary pulmonary nodule-comparison of three mathematical prediction models and further stratification of risk factors. PLoS One (2013) 0.80

Sortilin regulates progranulin action in castration-resistant prostate cancer cells. Endocrinology (2015) 0.80

Two-dimensional differential in-gel electrophoresis for identification of gastric cancer-specific protein markers. Oncol Rep (2009) 0.79