Randomised controlled trial to determine the clinical effectiveness and cost-effectiveness of selective serotonin reuptake inhibitors plus supportive care, versus supportive care alone, for mild to moderate depression with somatic symptoms in primary care: the THREAD (THREshold for AntiDepressant response) study.

PubWeight™: 1.80‹?› | Rank: Top 3%

🔗 View Article (PMID 19401066)

Published in Health Technol Assess on April 01, 2009

Authors

T Kendrick1, J Chatwin, C Dowrick, A Tylee, R Morriss, R Peveler, M Leese, P McCrone, T Harris, M Moore, R Byng, G Brown, S Barthel, H Mander, A Ring, V Kelly, V Wallace, M Gabbay, T Craig, A Mann

Author Affiliations

1: Primary Medical Care, Aldermoor Health Centre, University of Southampton, UK.

Articles citing this

Problem-solving therapy and supportive therapy in older adults with major depression and executive dysfunction: effect on disability. Arch Gen Psychiatry (2011) 2.00

Problem-solving therapy and supportive therapy in older adults with major depression and executive dysfunction. Am J Psychiatry (2010) 1.76

Depression management in primary care: an observational study of management changes related to PHQ-9 score for depression monitoring. Br J Gen Pract (2012) 1.06

Vitamin D and depression: a systematic review and meta-analysis comparing studies with and without biological flaws. Nutrients (2014) 1.05

Prescribing antidepressants for depression: time to be dimensional and inclusive. Br J Gen Pract (2011) 1.03

Depression in primary care patients with coronary heart disease: baseline findings from the UPBEAT UK study. PLoS One (2014) 0.89

Cost-effectiveness of a community-integrated home-based depression intervention in older African Americans. J Am Geriatr Soc (2014) 0.81

Practical clinical trials in psychopharmacology: a systematic review. J Clin Psychopharmacol (2015) 0.77

Cost-effectiveness of active monitoring versus antidepressants for major depression in primary health care: a 12-month non-randomized controlled trial (INFAP study). BMC Psychiatry (2015) 0.76

Quality of Life in Depressed Patients in UK Primary Care: The FINDER Study. Neurol Ther (2013) 0.76

Testing the McSad depression specific classification system in patients with somatic conditions: validity and performance. Health Qual Life Outcomes (2013) 0.76

Patient-reported outcome measures for monitoring primary care patients with depression: PROMDEP feasibility randomised trial. BMJ Open (2017) 0.75

SSRI plus supportive care more effective than supportive care alone for mild to moderate depression. Evid Based Ment Health (2009) 0.75

Articles by these authors

An inventory for measuring clinical anxiety: psychometric properties. J Consult Clin Psychol (1988) 26.07

Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis. Cell (1978) 14.82

Safety and effectiveness of nurse telephone consultation in out of hours primary care: randomised controlled trial. The South Wiltshire Out of Hours Project (SWOOP) Group. BMJ (1998) 10.82

Comparison of adaptive pacing therapy, cognitive behaviour therapy, graded exercise therapy, and specialist medical care for chronic fatigue syndrome (PACE): a randomised trial. Lancet (2011) 10.73

Observational study of effect of patient centredness and positive approach on outcomes of general practice consultations. BMJ (2001) 8.76

Evidence for the effects of HIV antibody counseling and testing on risk behaviors. JAMA (1991) 7.35

How useful is body mass index for comparison of body fatness across age, sex, and ethnic groups? Am J Epidemiol (1996) 7.12

Performance indicators for primary care groups: an evidence based approach. BMJ (1998) 6.97

Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group. J Clin Oncol (2000) 6.88

Long-acting beta2-agonist monotherapy vs continued therapy with inhaled corticosteroids in patients with persistent asthma: a randomized controlled trial. JAMA (2001) 6.55

TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease. Nature (2000) 6.54

Lay people's attitudes to treatment of depression: results of opinion poll for Defeat Depression Campaign just before its launch. BMJ (1996) 6.31

Preferences of patients for patient centred approach to consultation in primary care: observational study. BMJ (2001) 6.17

Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. Nature (2000) 5.86

Palliative medicine: is it really specialist territory? J R Soc Med (1998) 5.46

Cross sectional database analysis of antidepressant prescribing in general practice in the United Kingdom, 1993-5. BMJ (1996) 4.74

The chorio-allantoic membrane of the developing chick as a medium for the cultivation and histopathologic study of pathogenic fungi. Am J Pathol (1941) 4.64

Number of pregnancies and the subsequent risk of cardiovascular disease. N Engl J Med (1993) 4.30

Epidemic Diarrhoea and Vomiting. Br Med J (1945) 4.29

23-valent pneumococcal polysaccharide vaccine in HIV-1-infected Ugandan adults: double-blind, randomised and placebo controlled trial. Lancet (2000) 4.23

Gain of function mutations in p53. Nat Genet (1993) 4.19

Pragmatic randomised controlled trial of two prescribing strategies for childhood acute otitis media. BMJ (2001) 4.18

Recovery from psychotic illness: a 15- and 25-year international follow-up study. Br J Psychiatry (2001) 4.13

Cell adhesion and motility depend on nanoscale RGD clustering. J Cell Sci (2000) 4.13

Rural background and clinical rural rotations during medical training: effect on practice location. CMAJ (1999) 4.12

Characterization of tumor necrosis factor-deficient mice. Proc Natl Acad Sci U S A (1997) 4.10

Structural relationships between clathrin assembly proteins from the Golgi and the plasma membrane. EMBO J (1988) 4.06

The Chorioallantoic Membrane of Chick Embryos and Its Response to Inoculation with Some Mycobacteria. Am J Pathol (1942) 4.02

Measuring higher level physical function in well-functioning older adults: expanding familiar approaches in the Health ABC study. J Gerontol A Biol Sci Med Sci (2001) 4.01

Purification of human T and B lymphocytes. J Immunol (1974) 4.00

Inflammatory markers and cognition in well-functioning African-American and white elders. Neurology (2003) 3.99

Prevention of postoperative abdominal adhesions by a sodium hyaluronate-based bioresorbable membrane: a prospective, randomized, double-blind multicenter study. J Am Coll Surg (1996) 3.76

The treatment of depression: prescribing patterns of antidepressants in primary care in the UK. Br J Psychiatry (1996) 3.70

Appendicular skeletal muscle mass: effects of age, gender, and ethnicity. J Appl Physiol (1985) (1997) 3.63

Do clinical markers of barotrauma and oxygen toxicity explain interhospital variation in rates of chronic lung disease? The Neonatology Committee for the Developmental Network. Pediatrics (2000) 3.48

Relationship between hopelessness and ultimate suicide: a replication with psychiatric outpatients. Am J Psychiatry (1990) 3.45

TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease. impaired B cell maturation in mice lacking BLyS. Immunity (2001) 3.43

Measuring fitness in healthy older adults: the Health ABC Long Distance Corridor Walk. J Am Geriatr Soc (2001) 3.39

The adenovirus E1B-55K transforming polypeptide modulates transport or cytoplasmic stabilization of viral and host cell mRNAs. Mol Cell Biol (1986) 3.36

Weight change in old age and its association with mortality. J Am Geriatr Soc (2001) 3.26

Transferrin receptors in human tissues: their distribution and possible clinical relevance. J Clin Pathol (1983) 3.23

Establishment of a functional human immunodeficiency virus type 1 (HIV-1) reverse transcription complex involves the cytoskeleton. J Exp Med (1998) 3.22

Inhaled corticosteroid reduction and elimination in patients with persistent asthma receiving salmeterol: a randomized controlled trial. JAMA (2001) 3.21

Muscle strength and body mass index as long-term predictors of mortality in initially healthy men. J Gerontol A Biol Sci Med Sci (2000) 3.20

Spatially independent activity patterns in functional MRI data during the stroop color-naming task. Proc Natl Acad Sci U S A (1998) 3.18

Computerized, interactive, multimedia cognitive-behavioural program for anxiety and depression in general practice. Psychol Med (2003) 3.15

Antisera to acute lymphoblastic leukemia cells. Clin Immunol Immunopathol (1975) 3.12

Somatoform disorders: severe psychiatric illnesses neglected by psychiatrists. Br J Psychiatry (2001) 3.06

The natural history of familial cavernous malformations: results of an ongoing study. J Neurosurg (1994) 3.06

Self-reported causes of physical disability in older people: the Cardiovascular Health Study. CHS Collaborative Research Group. J Am Geriatr Soc (1994) 3.05

A study of clients returning for counseling after HIV testing: implications for improving rates of return. Public Health Rep (1993) 3.01

HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophages. Nat Med (1999) 3.01

The Defeat Depression Campaign: psychiatry in the public arena. Am J Psychiatry (1997) 3.00

Timer: a new objective measure of consultation content and its application to computer assisted consultations. Br Med J (Clin Res Ed) (1986) 3.00

Rationale and design. PRiSM Psychosis Study I. Br J Psychiatry (1998) 2.98

Depressive disorders in Europe: prevalence figures from the ODIN study. Br J Psychiatry (2001) 2.94

Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 receptor agonist. Nature (1999) 2.89

Multiple adenovirus serotypes use alpha v integrins for infection. J Virol (1994) 2.86

Tension pneumothorax--time for a re-think? Emerg Med J (2005) 2.80

Mental health care training priorities in general practice. Br J Gen Pract (1997) 2.79

Computer assisted screening: effect on the patient and his consultation. Br Med J (Clin Res Ed) (1985) 2.76

Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones. Biochem J (2000) 2.75

Randomised controlled trial of non-directive counselling, cognitive-behaviour therapy, and usual general practitioner care for patients with depression. I: clinical effectiveness. BMJ (2000) 2.72

Predictors of chronic "postviral" fatigue. Lancet (1994) 2.72

Depression in the community: the first pan-European study DEPRES (Depression Research in European Society). Int Clin Psychopharmacol (1997) 2.70

Tired, weak, or in need of rest: fatigue among general practice attenders. BMJ (1990) 2.70

Cell surface markers for human T and B lymphocytes. Eur J Immunol (1974) 2.70

Interleukin-6 and risk of cognitive decline: MacArthur studies of successful aging. Neurology (2002) 2.68

The role of psychosocial factors in predicting the onset of chronic widespread pain: results from a prospective population-based study. Rheumatology (Oxford) (2006) 2.66

Protection, pathogenesis and phenotypic plasticity in Plasmodium falciparum malaria. Parasitol Today (1993) 2.64

The Camberwell Assessment of Need: the validity and reliability of an instrument to assess the needs of people with severe mental illness. Br J Psychiatry (1995) 2.60

Relationship between trauma center volume and outcomes. JAMA (2001) 2.56

Processes of care, illness severity, and outcomes in the management of community-acquired pneumonia at academic hospitals. Arch Intern Med (2001) 2.51

HDL cholesterol predicts coronary heart disease mortality in older persons. JAMA (1995) 2.46

Blinded, randomized, multicenter study to evaluate single administration pegfilgrastim once per cycle versus daily filgrastim as an adjunct to chemotherapy in patients with high-risk stage II or stage III/IV breast cancer. J Clin Oncol (2002) 2.46

A systematic review of controlled trials of the effectiveness and cost-effectiveness of brief psychological treatments for depression. Health Technol Assess (2001) 2.46

Detention of people with dangerous severe personality disorders: a systematic review. Lancet (2001) 2.45

CAISSON DISEASE WITH SPECIAL REFERENCE TO THE BONES AND JOINTS: REPORT OF TWO CASES. Ann Surg (1940) 2.44

Computers in the surgery. The patient's view. Br Med J (Clin Res Ed) (1984) 2.43

Somatic presentation of psychiatric morbidity in general practice. Br J Gen Pract (1995) 2.39

Body mass index, weight change, and risk of mobility disability in middle-aged and older women. The epidemiologic follow-up study of NHANES I. JAMA (1994) 2.38

EUROCARE: a cross-national study of co-resident spouse carers for people with Alzheimer's disease: I--Factors associated with carer burden. Int J Geriatr Psychiatry (1999) 2.36

Dipsticks and diagnostic algorithms in urinary tract infection: development and validation, randomised trial, economic analysis, observational cohort and qualitative study. Health Technol Assess (2009) 2.36

Randomised controlled trial of self management leaflets and booklets for minor illness provided by post. BMJ (2001) 2.35

GFRalpha1 is an essential receptor component for GDNF in the developing nervous system and kidney. Neuron (1998) 2.34

Overnight calls in primary care: randomised controlled trial of management using nurse telephone consultation. BMJ (1999) 2.32

Association of interleukin-6 and other biologic variables with depression in older people living in the community. J Am Geriatr Soc (1999) 2.31

Tuberculosis among foreign-born persons in the United States, 1993-1998. JAMA (2000) 2.31

Validity of current clinical criteria for Alzheimer's disease, vascular dementia and dementia with Lewy bodies. Br J Psychiatry (1999) 2.31

The association of plasma IL-6 levels with functional disability in community-dwelling elderly. J Gerontol A Biol Sci Med Sci (1997) 2.27

Optimal total mesorectal excision for rectal cancer is by dissection in front of Denonvilliers' fascia. Br J Surg (2004) 2.26

Poverty, psychological disorder and disability in primary care attenders in Goa, India. Br J Psychiatry (1998) 2.25

Epithelial wound healing enhanced by transforming growth factor-alpha and vaccinia growth factor. Science (1987) 2.24

Validation study of a diary for use in acute lower respiratory tract infection. Fam Pract (2001) 2.24

Importance of lead selection in QT interval measurement. Am J Cardiol (1988) 2.23

Are investigations anxiolytic or anxiogenic? A randomised controlled trial of neuroimaging to provide reassurance in chronic daily headache. J Neurol Neurosurg Psychiatry (2005) 2.21

Parental influences on children's eating behavior and relative weight. J Appl Behav Anal (1983) 2.21