Recent decline in age at breast development: the Copenhagen Puberty Study.

PubWeight™: 2.09‹?› | Rank: Top 2%

🔗 View Article (PMID 19403485)

Published in Pediatrics on May 01, 2009

Authors

Lise Aksglaede1, Kaspar Sørensen, Jørgen H Petersen, Niels E Skakkebaek, Anders Juul

Author Affiliations

1: Rigshospitalet, Department of Growth and Reproduction GR, Section 5064, Blegdamsvej 9, DK-2100 Copenhagen Ø, Denmark. lise.aksglaede@rh.hosp.dk

Articles citing this

Pubertal assessment method and baseline characteristics in a mixed longitudinal study of girls. Pediatrics (2010) 2.51

Onset of breast development in a longitudinal cohort. Pediatrics (2013) 2.03

The pros and cons of phytoestrogens. Front Neuroendocrinol (2010) 1.69

Adolescence: what do transmission, transition, and translation have to do with it? Neuron (2010) 1.61

Hormone changes in peripubertal girls. J Clin Endocrinol Metab (2014) 1.49

Expert consensus document: European Consensus Statement on congenital hypogonadotropic hypogonadism--pathogenesis, diagnosis and treatment. Nat Rev Endocrinol (2015) 1.39

Accumulation and endocrine disrupting effects of the flame retardant mixture Firemaster® 550 in rats: an exploratory assessment. J Biochem Mol Toxicol (2012) 1.39

Trends in reproductive health in Israel: implications for environmental health policy. Isr J Health Policy Res (2012) 1.38

Age at puberty and the emerging obesity epidemic. PLoS One (2009) 1.37

Circulating levels of microRNA from children with newly diagnosed type 1 diabetes and healthy controls: evidence that miR-25 associates to residual beta-cell function and glycaemic control during disease progression. Exp Diabetes Res (2012) 1.17

What is in our environment that effects puberty? Reprod Toxicol (2013) 1.13

Effects of obesity on human sexual development. Nat Rev Endocrinol (2012) 1.13

Endocrine disrupters: a review of some sources, effects, and mechanisms of actions on behaviour and neuroendocrine systems. J Neuroendocrinol (2012) 1.09

High prevalence of daily and multi-site pain--a cross-sectional population-based study among 3000 Danish adolescents. BMC Pediatr (2013) 1.06

Long-term effects of environmental endocrine disruptors on reproductive physiology and behavior. Front Behav Neurosci (2009) 1.04

Nicotine and the adolescent brain. J Physiol (2015) 1.02

Presentation of 493 consecutive girls with idiopathic central precocious puberty: a single-center study. PLoS One (2013) 1.01

Dairy intake in relation to breast and pubertal development in Chilean girls. Am J Clin Nutr (2017) 0.99

Trends in menarcheal age between 1955 and 2009 in the Netherlands. PLoS One (2013) 0.99

Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of sites in a cell type-specific manner. Genome Res (2012) 0.97

The Changes They are A-Timed: Metabolism, Endogenous Clocks, and the Timing of Puberty. Front Endocrinol (Lausanne) (2012) 0.97

Role of prenatal characteristics and early growth on pubertal attainment of British girls. Pediatrics (2010) 0.97

Exposure to environmental endocrine disruptors and child development. Arch Pediatr Adolesc Med (2012) 0.95

Pathological and incidental findings on brain MRI in a single-center study of 229 consecutive girls with early or precocious puberty. PLoS One (2012) 0.94

Puberty in girls of the 21st century. J Pediatr Adolesc Gynecol (2012) 0.92

Maternal cigarette smoking during pregnancy and reproductive health in children: a review of epidemiological studies. Asian J Androl (2013) 0.92

LIN28B, LIN28A, KISS1, and KISS1R in idiopathic central precocious puberty. BMC Res Notes (2011) 0.91

Progression through puberty in girls enrolled in a contemporary British cohort. J Adolesc Health (2010) 0.91

Neonatal exposure to genistein adversely impacts the ontogeny of hypothalamic kisspeptin signaling pathways and ovarian development in the peripubertal female rat. Reprod Toxicol (2010) 0.88

Perinatal environmental exposures affect mammary development, function, and cancer risk in adulthood. Annu Rev Pharmacol Toxicol (2011) 0.87

Disrupted organization of RFamide pathways in the hypothalamus is associated with advanced puberty in female rats neonatally exposed to bisphenol A. Biol Reprod (2012) 0.87

A potential mechanism for the sexual dimorphism in the onset of puberty and incidence of idiopathic central precocious puberty in children: sex-specific kisspeptin as an integrator of puberty signals. Front Endocrinol (Lausanne) (2012) 0.87

Decline in age at menarche among Spanish women born from 1925 to 1962. BMC Public Health (2009) 0.86

Diet-induced metabolic change induces estrogen-independent allometric mammary growth. Proc Natl Acad Sci U S A (2012) 0.85

Neuroendocrine disruption: historical roots, current progress, questions for the future. Front Neuroendocrinol (2010) 0.85

Fat mass increase in 7-year-old children: more bone area but lower bone mineral density. J Bone Miner Metab (2013) 0.85

NMR-based metabolomic profiling of overweight adolescents: an elucidation of the effects of inter-/intraindividual differences, gender, and pubertal development. Biomed Res Int (2014) 0.84

Correspondence Between Gonadal Steroid Hormone Concentrations and Secondary Sexual Characteristics Assessed by Clinicians, Adolescents, and Parents. J Res Adolesc (2012) 0.83

Reproductive hormone profile and pubertal development in 14-year-old boys prenatally exposed to polychlorinated biphenyls. Reprod Toxicol (2012) 0.82

A mathematical model for predicting the adult height of girls with advanced puberty after spontaneous growth. BMC Pediatr (2014) 0.82

The effects of estradiol on mood and behavior in human female adolescents: a systematic review. Eur J Pediatr (2015) 0.81

Pubertal onset in girls is strongly influenced by genetic variation affecting FSH action. Sci Rep (2014) 0.81

Pubertal timing and body mass index gain from birth to maturity in relation with femoral neck BMD and distal tibia microstructure in healthy female subjects. Osteoporos Int (2011) 0.81

A Significant Increase in the Incidence of Central Precocious Puberty among Korean Girls from 2004 to 2010. PLoS One (2015) 0.80

Development of the human breast. Semin Plast Surg (2013) 0.80

Pubertal characteristics among schoolgirls in Riyadh, Saudi Arabia. Eur J Pediatr (2013) 0.80

Postweaning dietary genistein exposure advances puberty without significantly affecting early pregnancy in C57BL/6J female mice. Reprod Toxicol (2013) 0.80

Significant gender difference in serum levels of fibroblast growth factor 21 in Danish children and adolescents. Int J Pediatr Endocrinol (2014) 0.80

Pubertal development in healthy children is mirrored by DNA methylation patterns in peripheral blood. Sci Rep (2016) 0.79

Adolescent endogenous sex hormones and breast density in early adulthood. Breast Cancer Res (2015) 0.79

Pubertal pathways in girls enrolled in a contemporary british cohort. Int J Pediatr (2010) 0.79

Pubertal development and regulation. Lancet Diabetes Endocrinol (2016) 0.79

Mutation of kisspeptin 1 gene in children with precocious puberty in isfahan city. Int J Prev Med (2015) 0.78

Association Between Urinary Phthalates and Pubertal Timing in Chinese Adolescents. J Epidemiol (2015) 0.78

Age of thelarche and menarche in contemporary US females: a cross-sectional analysis. J Pediatr Endocrinol Metab (2014) 0.78

Timing of Environmental Exposures as a Critical Element in Breast Cancer Risk. J Clin Endocrinol Metab (2015) 0.78

Does puberty mark a transition in sensitive periods for plasticity in the associative neocortex? Brain Res (2016) 0.77

Associations of Peripubertal Serum Dioxin and Polychlorinated Biphenyl Concentrations with Pubertal Timing among Russian Boys. Environ Health Perspect (2016) 0.77

The Relationship Between Greater Prepubertal Adiposity, Subsequent Age of Maturation, and Bone Strength During Adolescence. J Bone Miner Res (2016) 0.77

Pediatrics: endocrine disruption and human health effects--a call to action. Nat Rev Endocrinol (2011) 0.76

Is soy intake related to age at onset of menarche? A cross-sectional study among adolescents with a wide range of soy food consumption. Nutr J (2014) 0.76

Roles of physical activity and cardiorespiratory fitness on sex difference in insulin resistance in late elementary years. J Exerc Nutrition Biochem (2014) 0.76

Urinary bisphenol a levels in girls with idiopathic central precocious puberty. J Clin Res Pediatr Endocrinol (2014) 0.76

Phthalate and bisphenol A exposure during in utero windows of susceptibility in relation to reproductive hormones and pubertal development in girls. Environ Res (2017) 0.76

Endocrine disruption by dietary phyto-oestrogens: impact on dimorphic sexual systems and behaviours. Proc Nutr Soc (2016) 0.76

Increasing incidence of premature thelarche in the Central Region of Denmark - Challenges in differentiating girls less than 7 years of age with premature thelarche from girls with precocious puberty in real-life practice. Int J Pediatr Endocrinol (2016) 0.75

POPs and Pubertal Timing: Evidence of Delayed Development. Environ Health Perspect (2015) 0.75

Glandular breast tissue volume by magnetic resonance imaging in 100 healthy peripubertal girls: evaluation of clinical Tanner staging. Pediatr Res (2016) 0.75

Ethnic differences in leptin and adiponectin levels between Greenlandic Inuit and Danish children. Int J Circumpolar Health (2013) 0.75

Associations of urinary phthalate and phenol biomarkers with menarche in a multiethnic cohort of young girls. Reprod Toxicol (2016) 0.75

Urinary Sex Steroids and Anthropometric Markers of Puberty - A Novel Approach to Characterising Within-Person Changes of Puberty Hormones. PLoS One (2015) 0.75

Effect of Nourishing "Yin" Removing "Fire" Chinese Herbal Mixture on Hypothalamic Mammalian Target of Rapamycin Expression during Onset of Puberty in Female Rats. Evid Based Complement Alternat Med (2015) 0.75

DNA methylation of LINE-1 and Alu repetitive elements in relation to sex hormones and pubertal timing in Mexican-American children. Pediatr Res (2016) 0.75

Prenatal exposure to vitamin D from fortified margarine and risk of fractures in late childhood: period and cohort results from 222 000 subjects in the D-tect observational study. Br J Nutr (2017) 0.75

The mystery of puberty initiation: genetics and epigenetics of idiopathic central precocious puberty (ICPP). J Endocrinol Invest (2017) 0.75

Age and time trends in eating frequency and duration of nightly fasting of German children and adolescents. Eur J Nutr (2016) 0.75

Vitamin D status of Icelandic children and its influence on bone accrual. J Bone Miner Metab (2015) 0.75

The Effect of Bisphenol A on Puberty: A Critical Review of the Medical Literature. Int J Environ Res Public Health (2017) 0.75

Articles by these authors

The timing of normal puberty and the age limits of sexual precocity: variations around the world, secular trends, and changes after migration. Endocr Rev (2003) 4.88

Examination of US puberty-timing data from 1940 to 1994 for secular trends: panel findings. Pediatrics (2008) 3.74

Human breast milk contamination with phthalates and alterations of endogenous reproductive hormones in infants three months of age. Environ Health Perspect (2006) 2.73

Consensus statement on the use of gonadotropin-releasing hormone analogs in children. Pediatrics (2009) 2.67

Body mass index in relation to semen quality and reproductive hormones among 1,558 Danish men. Fertil Steril (2004) 2.40

Public health implications of altered puberty timing. Pediatrics (2008) 2.26

ATM activation in normal human tissues and testicular cancer. Cell Cycle (2005) 2.25

European consensus conference on diagnosis and treatment of germ cell cancer: a report of the second meeting of the European Germ Cell Cancer Consensus group (EGCCCG): part I. Eur Urol (2007) 2.21

Using electronic patient records to discover disease correlations and stratify patient cohorts. PLoS Comput Biol (2011) 2.14

Cryptorchidism and hypospadias as a sign of testicular dysgenesis syndrome (TDS): environmental connection. Birth Defects Res A Clin Mol Teratol (2010) 2.04

Human semen quality in the new millennium: a prospective cross-sectional population-based study of 4867 men. BMJ Open (2012) 2.03

Vitamin D receptor and vitamin D metabolizing enzymes are expressed in the human male reproductive tract. Hum Reprod (2010) 2.00

Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat. Hum Reprod (2010) 1.97

Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effects. Fertil Steril (2008) 1.96

East-West gradient in semen quality in the Nordic-Baltic area: a study of men from the general population in Denmark, Norway, Estonia and Finland. Hum Reprod (2002) 1.91

Do perfluoroalkyl compounds impair human semen quality? Environ Health Perspect (2009) 1.81

Environmental chemicals and thyroid function. Eur J Endocrinol (2006) 1.75

Systemic absorption of the sunscreens benzophenone-3, octyl-methoxycinnamate, and 3-(4-methyl-benzylidene) camphor after whole-body topical application and reproductive hormone levels in humans. J Invest Dermatol (2004) 1.73

Metabolism of phthalates in humans. Mol Nutr Food Res (2007) 1.70

Caffeine intake and semen quality in a population of 2,554 young Danish men. Am J Epidemiol (2010) 1.69

Estimating burden and disease costs of exposure to endocrine-disrupting chemicals in the European union. J Clin Endocrinol Metab (2015) 1.64

Larger testes and higher inhibin B levels in Finnish than in Danish newborn boys. J Clin Endocrinol Metab (2006) 1.63

Childhood exposure to phthalates: associations with thyroid function, insulin-like growth factor I, and growth. Environ Health Perspect (2010) 1.60

Female reproductive disorders: the roles of endocrine-disrupting compounds and developmental timing. Fertil Steril (2008) 1.60

Prenatal and adult exposures to smoking are associated with adverse effects on reproductive hormones, semen quality, final height and body mass index. Hum Reprod (2011) 1.60

Sperm counts, data responsibility, and good scientific practice. Epidemiology (2011) 1.59

Urinary excretion of phthalates and paraben after repeated whole-body topical application in humans. Int J Androl (2008) 1.58

Embryonic stem cell-like features of testicular carcinoma in situ revealed by genome-wide gene expression profiling. Cancer Res (2004) 1.56

Environmental factors and puberty timing: expert panel research needs. Pediatrics (2008) 1.54

Is human fecundity declining? Int J Androl (2006) 1.52

From embryonic stem cells to testicular germ cell cancer-- should we be concerned? Int J Androl (2006) 1.48

Science and policy on endocrine disrupters must not be mixed: a reply to a "common sense" intervention by toxicology journal editors. Environ Health (2013) 1.42

Association Between Use of Marijuana and Male Reproductive Hormones and Semen Quality: A Study Among 1,215 Healthy Young Men. Am J Epidemiol (2015) 1.41

Duration of adrenal insufficiency during treatment for childhood acute lymphoblastic leukemia. J Pediatr Hematol Oncol (2011) 1.41

Phenotypic characterisation of immune cell infiltrates in testicular germ cell neoplasia. J Reprod Immunol (2013) 1.41

[Pituitary insufficiency following head trauma]. Ugeskr Laeger (2007) 1.39

Association of in utero exposure to maternal smoking with reduced semen quality and testis size in adulthood: a cross-sectional study of 1,770 young men from the general population in five European countries. Am J Epidemiol (2004) 1.38

The BoneXpert method for automated determination of skeletal maturity. IEEE Trans Med Imaging (2009) 1.37

European consensus conference on diagnosis and treatment of germ cell cancer: a report of the second meeting of the European Germ Cell Cancer Consensus Group (EGCCCG): part II. Eur Urol (2007) 1.37

Age at puberty and the emerging obesity epidemic. PLoS One (2009) 1.37

Serum levels of anti-Müllerian hormone as a marker of ovarian function in 926 healthy females from birth to adulthood and in 172 Turner syndrome patients. J Clin Endocrinol Metab (2010) 1.37

Analysis of gene expression profiles of microdissected cell populations indicates that testicular carcinoma in situ is an arrested gonocyte. Cancer Res (2009) 1.35

Developmental expression of POU5F1 (OCT-3/4) in normal and dysgenetic human gonads. Hum Reprod (2004) 1.34

Role of environmental factors in the timing of puberty. Pediatrics (2008) 1.33

Persistent pesticides in human breast milk and cryptorchidism. Environ Health Perspect (2006) 1.33

Effects of ejaculatory frequency and season on variations in semen quality. Fertil Steril (2004) 1.32

Increased number of sex chromosomes affects height in a nonlinear fashion: a study of 305 patients with sex chromosome aneuploidy. Am J Med Genet A (2010) 1.31

Recent changes in pubertal timing in healthy Danish boys: associations with body mass index. J Clin Endocrinol Metab (2009) 1.29

The impact of endocrine disruption: a consensus statement on the state of the science. Environ Health Perspect (2013) 1.28

Secular decline in male testosterone and sex hormone binding globulin serum levels in Danish population surveys. J Clin Endocrinol Metab (2007) 1.28

Mild gestational diabetes as a risk factor for congenital cryptorchidism. J Clin Endocrinol Metab (2006) 1.27

Transcription factor AP-2gamma is a developmentally regulated marker of testicular carcinoma in situ and germ cell tumors. Clin Cancer Res (2004) 1.27

Sex differences in the vaccine-specific and non-targeted effects of vaccines. Vaccine (2011) 1.27

Recent secular trends in pubertal timing: implications for evaluation and diagnosis of precocious puberty. Horm Res Paediatr (2012) 1.26

Postnatal penile length and growth rate correlate to serum testosterone levels: a longitudinal study of 1962 normal boys. Eur J Endocrinol (2006) 1.26

Coordinated European investigations of semen quality: results from studies of Scandinavian young men is a matter of concern. Int J Androl (2006) 1.26

The emerging phenotype of the testicular carcinoma in situ germ cell. APMIS (2003) 1.24

Forty years trends in timing of pubertal growth spurt in 157,000 Danish school children. PLoS One (2008) 1.24

Animal protein intake, serum insulin-like growth factor I, and growth in healthy 2.5-y-old Danish children. Am J Clin Nutr (2004) 1.23

Semen quality in sub-fertile range for a significant proportion of young men from the general German population: a co-ordinated, controlled study of 791 men from Hamburg and Leipzig. Int J Androl (2008) 1.23

Serum inhibin B and follicle-stimulating hormone levels as tools in the evaluation of infertile men: significance of adequate reference values from proven fertile men. J Clin Endocrinol Metab (2004) 1.23

Declining trends in conception rates in recent birth cohorts of native Danish women: a possible role of deteriorating male reproductive health. Int J Androl (2007) 1.22

Diagnostic work-up of 449 consecutive girls who were referred to be evaluated for precocious puberty. J Clin Endocrinol Metab (2011) 1.22

Klinefelter syndrome: expanding the phenotype and identifying new research directions. Genet Med (2003) 1.21

The pubertal transition in 179 healthy Danish children: associations between pubarche, adrenarche, gonadarche, and body composition. Eur J Endocrinol (2012) 1.21

Assessment of circulating sex steroid levels in prepubertal and pubertal boys and girls by a novel ultrasensitive gas chromatography-tandem mass spectrometry method. J Clin Endocrinol Metab (2009) 1.21

Maximum likelihood estimation for Cox's regression model under nested case-control sampling. Biostatistics (2004) 1.18

Circulating levels of microRNA from children with newly diagnosed type 1 diabetes and healthy controls: evidence that miR-25 associates to residual beta-cell function and glycaemic control during disease progression. Exp Diabetes Res (2012) 1.17

The relationship between anogenital distance and reproductive hormone levels in adult men. J Urol (2011) 1.16

Testicular dysgenesis syndrome: possible role of endocrine disrupters. Best Pract Res Clin Endocrinol Metab (2006) 1.16

Cryptorchidism and maternal alcohol consumption during pregnancy. Environ Health Perspect (2006) 1.14

Regional differences in semen qualities in the Baltic region. Int J Androl (2002) 1.14

Presumed pluripotency markers UTF-1 and REX-1 are expressed in human adult testes and germ cell neoplasms. Hum Reprod (2008) 1.13

Dual effects of phytoestrogens result in u-shaped dose-response curves. Environ Health Perspect (2002) 1.12

[Growth references for Norwegian children]. Tidsskr Nor Laegeforen (2009) 1.12

Low concentration of circulating antimüllerian hormone is not predictive of reduced fecundability in young healthy women: a prospective cohort study. Fertil Steril (2012) 1.12

Origin of pluripotent germ cell tumours: the role of microenvironment during embryonic development. Mol Cell Endocrinol (2008) 1.11

Increased risk of carcinoma in situ in patients with testicular germ cell cancer with ultrasonic microlithiasis in the contralateral testicle. J Urol (2003) 1.11

GH administration changes myosin heavy chain isoforms in skeletal muscle but does not augment muscle strength or hypertrophy, either alone or combined with resistance exercise training in healthy elderly men. J Clin Endocrinol Metab (2002) 1.10

Prevalence and incidence of precocious pubertal development in Denmark: an epidemiologic study based on national registries. Pediatrics (2005) 1.09

Abnormal sex chromosome constitution and longitudinal growth: serum levels of insulin-like growth factor (IGF)-I, IGF binding protein-3, luteinizing hormone, and testosterone in 109 males with 47,XXY, 47,XYY, or sex-determining region of the Y chromosome (SRY)-positive 46,XX karyotypes. J Clin Endocrinol Metab (2007) 1.09

Analysis of cell-type-specific gene expression during mouse spermatogenesis. Biol Reprod (2004) 1.09

The 2014 Danish references from birth to 20 years for height, weight and body mass index. Acta Paediatr (2013) 1.09

Longitudinal changes in semen parameters in young Danish men from the Copenhagen area. Hum Reprod (2005) 1.08