Published in FASEB J on May 05, 2009
RTX proteins: a highly diverse family secreted by a common mechanism. FEMS Microbiol Rev (2010) 2.13
Pertussis toxin and adenylate cyclase toxin: key virulence factors of Bordetella pertussis and cell biology tools. Future Microbiol (2010) 1.30
Bordetella adenylate cyclase toxin mobilizes its beta2 integrin receptor into lipid rafts to accomplish translocation across target cell membrane in two steps. PLoS Pathog (2010) 1.04
Selective translocation of the Bordetella pertussis adenylate cyclase toxin across the basolateral membranes of polarized epithelial cells. J Biol Chem (2010) 1.00
Identification of a region that assists membrane insertion and translocation of the catalytic domain of Bordetella pertussis CyaA toxin. J Biol Chem (2012) 0.88
Disorder-to-order transition in the CyaA toxin RTX domain: implications for toxin secretion. Toxins (Basel) (2014) 0.87
Differences in purinergic amplification of osmotic cell lysis by the pore-forming RTX toxins Bordetella pertussis CyaA and Actinobacillus pleuropneumoniae ApxIA: the role of pore size. Infect Immun (2013) 0.86
Charge-dependent secretion of an intrinsically disordered protein via the autotransporter pathway. Proc Natl Acad Sci U S A (2013) 0.86
Role of CD11b/CD18 in the process of intoxication by the adenylate cyclase toxin of Bordetella pertussis. Infect Immun (2011) 0.86
Calcium influx rescues adenylate cyclase-hemolysin from rapid cell membrane removal and enables phagocyte permeabilization by toxin pores. PLoS Pathog (2012) 0.85
Calcium, acylation, and molecular confinement favor folding of Bordetella pertussis adenylate cyclase CyaA toxin into a monomeric and cytotoxic form. J Biol Chem (2014) 0.83
Bordetella adenylate cyclase toxin: a unique combination of a pore-forming moiety with a cell-invading adenylate cyclase enzyme. Pathog Dis (2015) 0.82
Delivery of large heterologous polypeptides across the cytoplasmic membrane of antigen-presenting cells by the Bordetella RTX hemolysin moiety lacking the adenylyl cyclase domain. Infect Immun (2012) 0.79
Membrane-Pore Forming Characteristics of the Bordetella pertussis CyaA-Hemolysin Domain. Toxins (Basel) (2015) 0.78
Pore-formation by adenylate cyclase toxoid activates dendritic cells to prime CD8(+) and CD4(+) T cells. Immunol Cell Biol (2015) 0.77
The deletion of several amino acid stretches of Escherichia coli alpha-hemolysin (HlyA) suggests that the channel-forming domain contains beta-strands. PLoS One (2014) 0.76
cAMP-elevating capacity of the adenylate cyclase toxin-hemolysin is sufficient for lung infection but not for full virulence of Bordetella pertussis. Infect Immun (2017) 0.76
Stability, structural and functional properties of a monomeric, calcium-loaded adenylate cyclase toxin, CyaA, from Bordetella pertussis. Sci Rep (2017) 0.75
Albumin, in the presence of calcium, elicits a massive increase in extracellular Bordetella adenylate cyclase toxin. Infect Immun (2017) 0.75
General and molecular microbiology and microbial genetics in the IM CAS. J Ind Microbiol Biotechnol (2010) 0.75
Type VI secretion apparatus and phage tail-associated protein complexes share a common evolutionary origin. Proc Natl Acad Sci U S A (2009) 4.88
T-cell engagement of dendritic cells rapidly rearranges MHC class II transport. Nature (2002) 3.93
Sustained small interfering RNA-mediated human immunodeficiency virus type 1 inhibition in primary macrophages. J Virol (2003) 2.26
RTX proteins: a highly diverse family secreted by a common mechanism. FEMS Microbiol Rev (2010) 2.13
β-synuclein aggregates and induces neurodegeneration in dopaminergic neurons. Ann Neurol (2013) 2.10
Integrin subunit CD18 Is the T-lymphocyte receptor for the Helicobacter pylori vacuolating cytotoxin. Cell Host Microbe (2008) 1.96
Segmented filamentous bacteria in a defined bacterial cocktail induce intestinal inflammation in SCID mice reconstituted with CD45RBhigh CD4+ T cells. Inflamm Bowel Dis (2007) 1.73
Transmission of Mycobacterium tuberculosis undetected by tuberculin skin testing. Am J Respir Crit Care Med (2006) 1.72
Assembly and iron-binding properties of human frataxin, the protein deficient in Friedreich ataxia. Hum Mol Genet (2002) 1.54
An increase in antimycobacterial Th1-cell responses by prime-boost protocols of immunization does not enhance protection against tuberculosis. Infect Immun (2006) 1.51
Inflammasome activation by adenylate cyclase toxin directs Th17 responses and protection against Bordetella pertussis. J Immunol (2010) 1.48
Bordetella adenylate cyclase toxin: a swift saboteur of host defense. Curr Opin Microbiol (2006) 1.47
Hypertrophic pulmonary osteoarthropathy disappearance despite lung cancer relapse. South Med J (2008) 1.38
Structural properties of pore-forming oligomers of alpha-synuclein. J Am Chem Soc (2009) 1.36
Cholesterol-dependent pore formation of Clostridium difficile toxin A. J Biol Chem (2006) 1.32
Structural determinants for membrane insertion, pore formation and translocation of Clostridium difficile toxin B. Mol Microbiol (2011) 1.30
High frequency of CD4+ T cells specific for the TB10.4 protein correlates with protection against Mycobacterium tuberculosis infection. Infect Immun (2006) 1.26
Biocomputational prediction of small non-coding RNAs in Streptomyces. BMC Genomics (2008) 1.25
Pore-forming and enzymatic activities of Bordetella pertussis adenylate cyclase toxin synergize in promoting lysis of monocytes. Infect Immun (2006) 1.25
Eukaryotic-type serine/threonine protein kinase StkP is a global regulator of gene expression in Streptococcus pneumoniae. J Bacteriol (2007) 1.24
An RND-type efflux system in Borrelia burgdorferi is involved in virulence and resistance to antimicrobial compounds. PLoS Pathog (2008) 1.21
Anthrax toxin protective antigen: inhibition of channel function by chloroquine and related compounds and study of binding kinetics using the current noise analysis. Biophys J (2004) 1.20
Lipid II-mediated pore formation by the peptide antibiotic nisin: a black lipid membrane study. J Bacteriol (2004) 1.17
Regulation of glycolysis by Raf protein serine/threonine kinases. Adv Enzyme Regul (2002) 1.15
Interaction of Bordetella pertussis adenylate cyclase with CD11b/CD18: Role of toxin acylation and identification of the main integrin interaction domain. J Biol Chem (2003) 1.15
Homing and conversion of murine hematopoietic stem cells to lung. Blood Cells Mol Dis (2004) 1.15
Membrane restructuring by Bordetella pertussis adenylate cyclase toxin, a member of the RTX toxin family. J Bacteriol (2004) 1.13
A novel "clip-and-link" activity of repeat in toxin (RTX) proteins from gram-negative pathogens. Covalent protein cross-linking by an Asp-Lys isopeptide bond upon calcium-dependent processing at an Asp-Pro bond. J Biol Chem (2004) 1.11
RTX cytotoxins recognize beta2 integrin receptors through N-linked oligosaccharides. Proc Natl Acad Sci U S A (2008) 1.10
Characterization of dominantly negative mutant ClyA cytotoxin proteins in Escherichia coli. J Bacteriol (2003) 1.10
T cells induce extended class II MHC compartments in dendritic cells in a Toll-like receptor-dependent manner. J Immunol (2003) 1.09
Interaction of Clostridium perfringens iota-toxin with lipid bilayer membranes. Demonstration of channel formation by the activated binding component Ib and channel block by the enzyme component Ia. J Biol Chem (2001) 1.07
Diffusion through channel derivatives of the Escherichia coli FhuA transport protein. Eur J Biochem (2002) 1.06
Elimination of channel-forming activity by insertional inactivation of the p13 gene in Borrelia burgdorferi. J Bacteriol (2002) 1.06
Antigen targeting to CD11b allows efficient presentation of CD4+ and CD8+ T cell epitopes and in vivo Th1-polarized T cell priming. J Immunol (2004) 1.06
Interaction of bacteriophage lambda with its cell surface receptor: an in vitro study of binding of the viral tail protein gpJ to LamB (Maltoporin). Biochemistry (2006) 1.06
Adenylate cyclase toxin subverts phagocyte function by RhoA inhibition and unproductive ruffling. J Immunol (2008) 1.06
ClyA cytolysin from Salmonella: distribution within the genus, regulation of expression by SlyA, and pore-forming characteristics. Int J Med Microbiol (2008) 1.05
Antibody responses to mycobacterial and self heat shock protein 65 in autoimmune arthritis: epitope specificity and implication in pathogenesis. J Immunol (2006) 1.05
Mutations in bone marrow-derived stromal stem cells unmask latent malignancy. Stem Cells Dev (2010) 1.05
Characterization of the flexible genome complement of the commensal Escherichia coli strain A0 34/86 (O83 : K24 : H31). Microbiology (2005) 1.04
Bordetella adenylate cyclase toxin mobilizes its beta2 integrin receptor into lipid rafts to accomplish translocation across target cell membrane in two steps. PLoS Pathog (2010) 1.04
Negative regulation of mitochondrial VDAC channels by C-Raf kinase. BMC Cell Biol (2002) 1.04
Culture-negative infective endocarditis caused by Aerococcus urinae. J Heart Valve Dis (2007) 1.04
β-Barrel mobility underlies closure of the voltage-dependent anion channel. Structure (2012) 1.04
Type 6 secretion system-mediated immunity to type 4 secretion system-mediated gene transfer. Science (2013) 1.03
Structures of sequential open states in a symmetrical opening transition of the TolC exit duct. Proc Natl Acad Sci U S A (2011) 1.03
Clostridium botulinum C2 toxin: low pH-induced pore formation is required for translocation of the enzyme component C2I into the cytosol of host cells. J Biol Chem (2003) 1.02
Pxmp2 is a channel-forming protein in Mammalian peroxisomal membrane. PLoS One (2009) 1.01
Clostridium perfringens delta toxin is sequence related to beta toxin, NetB, and Staphylococcus pore-forming toxins, but shows functional differences. PLoS One (2008) 1.01
Identification of a ubiquitously active promoter of the murine activation-induced cytidine deaminase (AICDA) gene. Mol Immunol (2005) 1.01
Current treatment options: impact of cytogenetics on the course of myelodysplasia. Curr Treat Options Oncol (2007) 1.00
A syringe-like injection mechanism in Photorhabdus luminescens toxins. Nature (2013) 1.00
Porin OmpP2 of Haemophilus influenzae shows specificity for nicotinamide-derived nucleotide substrates. J Biol Chem (2003) 0.99
A novel outer-membrane anion channel (porin) as part of a putatively two-component transport system for 4-toluenesulphonate in Comamonas testosteroni T-2. Biochem J (2004) 0.99
Core/shell nanofibers with embedded liposomes as a drug delivery system. Biomacromolecules (2012) 0.98
Intrinsic hematopoietic stem cell/progenitor plasticity: Inversions. J Cell Physiol (2004) 0.98
Insecticidal toxin complex proteins from Xenorhabdus nematophilus: structure and pore formation. J Biol Chem (2011) 0.98
Acylation of lysine 860 allows tight binding and cytotoxicity of Bordetella adenylate cyclase on CD11b-expressing cells. Biochemistry (2005) 0.98
Determination of the conformation of the human VDAC1 N-terminal peptide, a protein moiety essential for the functional properties of the pore. Chembiochem (2007) 0.98
Enhanced ex vivo stimulation of Mycobacterium tuberculosis-specific T cells in human immunodeficiency virus-infected persons via antigen delivery by the Bordetella pertussis adenylate cyclase vector. Clin Vaccine Immunol (2007) 0.98
The visual system in subterranean African mole-rats (Rodentia, Bathyergidae): retina, subcortical visual nuclei and primary visual cortex. Brain Res Bull (2007) 0.97
Identification of an anion-specific channel in the cell wall of the Gram-positive bacterium Corynebacterium glutamicum. Mol Microbiol (2003) 0.97
The Blk pathway functions as a tumor suppressor in chronic myeloid leukemia stem cells. Nat Genet (2012) 0.97
Yno1p/Aim14p, a NADPH-oxidase ortholog, controls extramitochondrial reactive oxygen species generation, apoptosis, and actin cable formation in yeast. Proc Natl Acad Sci U S A (2012) 0.97
Transcriptomic identification of iron-regulated and iron-independent gene copies within the heavily duplicated Trichomonas vaginalis genome. Genome Biol Evol (2012) 0.96
Requirements for T cell-polarized tubulation of class II+ compartments in dendritic cells. J Immunol (2003) 0.96
Elimination of channel-forming activity by insertional inactivation of the p66 gene in Borrelia burgdorferi. FEMS Microbiol Lett (2007) 0.96
Chronic myelomonocytic leukemia evolving from preexisting myelodysplasia shares many features with de novo disease. Am J Clin Pathol (2006) 0.95
Efficient Ex vivo stimulation of Mycobacterium tuberculosis-specific T cells by genetically detoxified Bordetella pertussis adenylate cyclase antigen toxoids. Infect Immun (2005) 0.95
The Neisseria meningitidis outer membrane lipoprotein FrpD binds the RTX protein FrpC. J Biol Chem (2004) 0.95
Heterologous expression of full-length capsid protein of porcine circovirus 2 in Escherichia coli and its potential use for detection of antibodies. J Virol Methods (2009) 0.95
Channel formation by the binding component of Clostridium botulinum C2 toxin: glutamate 307 of C2II affects channel properties in vitro and pH-dependent C2I translocation in vivo. Biochemistry (2003) 0.95
The mechanism of gingiva metallic pigmentations formation. Clin Oral Investig (2008) 0.94
O-mycoloylated proteins from Corynebacterium: an unprecedented post-translational modification in bacteria. J Biol Chem (2010) 0.94