Published in Int J Oncol on June 01, 2009
G protein-coupled receptors: novel targets for drug discovery in cancer. Nat Rev Drug Discov (2011) 3.31
The renin-angiotensin system and cancer: old dog, new tricks. Nat Rev Cancer (2010) 1.62
A modern understanding of the traditional and nontraditional biological functions of angiotensin-converting enzyme. Pharmacol Rev (2012) 1.31
Angiotensin II facilitates breast cancer cell migration and metastasis. PLoS One (2012) 0.97
Differential gene expression profiling of human bone marrow-derived mesenchymal stem cells during adipogenic development. BMC Genomics (2011) 0.93
The roles of beta-adrenergic receptors in tumorigenesis and the possible use of beta-adrenergic blockers for cancer treatment: possible genetic and cell-signaling mechanisms. Cancer Manag Res (2012) 0.81
miR-802 regulates human angiotensin II type 1 receptor expression in intestinal epithelial C2BBe1 cells. Am J Physiol Gastrointest Liver Physiol (2010) 0.81
Lack of an association between angiotensin receptor blocker based therapy and increased risk of cancer: evidence from large observational studies. PLoS One (2015) 0.78
Role of renin-angiotensin system in gastric oncogenesis. J Gastroenterol Hepatol (2012) 0.77
Angiotensin II: immunohistochemical study in Sardinian pterygium. Eur J Histochem (2014) 0.76
The angiotensin II type 1 receptor antagonist telmisartan inhibits cell proliferation and tumor growth of esophageal adenocarcinoma via the AMPKα/mTOR pathway in vitro and in vivo. Oncotarget (2016) 0.76
Immune Modulation From Five Major Mushrooms: Application to Integrative Oncology. Integr Med (Encinitas) (2014) 0.75
Angiotensin receptor blocker telmisartan inhibits cell proliferation and tumor growth of cholangiocarcinoma through cell cycle arrest. Int J Oncol (2017) 0.75
Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival. Nat Med (2012) 5.44
Biliary papillary tumors share pathological features with intraductal papillary mucinous neoplasm of the pancreas. Hepatology (2006) 2.83
FGFR2-amplified gastric cancer cell lines require FGFR2 and Erbb3 signaling for growth and survival. Cancer Res (2008) 2.46
Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling. Proc Natl Acad Sci U S A (2007) 2.30
Cronkhite-Canada syndrome containing colon cancer and serrated adenoma lesions. Digestion (2004) 2.19
Outcome of ratio of lymph node metastasis in gastric carcinoma. Ann Surg Oncol (2002) 2.01
Biliary cystic tumors with bile duct communication: a cystic variant of intraductal papillary neoplasm of the bile duct. Mod Pathol (2006) 1.86
Meta-analysis of the results of randomized controlled trials that compared laparoscopic and open surgery for acute appendicitis. J Gastrointest Surg (2012) 1.84
Sentinel node mapping for gastric cancer: a prospective multicenter trial in Japan. J Clin Oncol (2013) 1.79
Guidelines for the management of biliary tract and ampullary carcinomas: surgical treatment. J Hepatobiliary Pancreat Surg (2008) 1.60
Immunoglobulin G4-related periaortitis complicated by aortic rupture and aortoduodenal fistula after endovascular AAA repair. J Endovasc Ther (2014) 1.59
Gene amplification of ESR1 in breast cancers--fact or fiction? A fluorescence in situ hybridization and multiplex ligation-dependent probe amplification study. J Pathol (2012) 1.55
Carcinogenesis in mouse stomach by simultaneous activation of the Wnt signaling and prostaglandin E2 pathway. Gastroenterology (2006) 1.47
Phase II study of oral S-1 for treatment of metastatic colorectal carcinoma. Cancer (2004) 1.44
Immunohistochemical assessment for estrogen receptor and progesterone receptor status in breast cancer: analysis for a cut-off point as the predictor for endocrine therapy. Breast Cancer (2004) 1.41
Prognostic value of microsatellite instability in resectable pancreatic cancer. Clin Cancer Res (2002) 1.39
Pancreas head carcinoma: frequency of invasion to soft tissue adherent to the superior mesenteric artery. Am J Surg Pathol (2005) 1.38
An opposing view on WWOX protein function as a tumor suppressor. Cancer Res (2003) 1.27
Role of the stemness factors sox2, oct3/4, and nanog in gastric carcinoma. J Surg Res (2010) 1.27
The overexpression of polycomb group proteins Bmi1 and EZH2 is associated with the progression and aggressive biological behavior of hepatocellular carcinoma. Lab Invest (2008) 1.26
Activation of lipogenic pathway correlates with cell proliferation and poor prognosis in hepatocellular carcinoma. J Hepatol (2008) 1.25
Primary leiomyosarcoma of the breast: report of a case. Surg Today (2002) 1.23
Keratinocyte growth factor produced by gastric fibroblasts specifically stimulates proliferation of cancer cells from scirrhous gastric carcinoma. Cancer Res (2003) 1.22
Inhibition of cyclooxygenase-2 suppresses lymph node metastasis via reduction of lymphangiogenesis. Cancer Res (2007) 1.21
A meta-analysis of the short- and long-term results of randomized controlled trials that compared laparoscopy-assisted and open colectomy for colon cancer. J Cancer (2012) 1.18
Predictive risk factors for clinically relevant pancreatic fistula analyzed in 1,239 patients with pancreaticoduodenectomy: multicenter data collection as a project study of pancreatic surgery by the Japanese Society of Hepato-Biliary-Pancreatic Surgery. J Hepatobiliary Pancreat Sci (2011) 1.18
Biliary tract cancer treatment: results from the Biliary Tract Cancer Statistics Registry in Japan. J Hepatobiliary Pancreat Surg (2002) 1.17
Innervation of the pancreas from the perspective of perineural invasion of pancreatic cancer. Pancreas (2003) 1.17
A nomogram predicting disease-free survival in patients with colorectal liver metastases treated with hepatic resection: multicenter data collection as a Project Study for Hepatic Surgery of the Japanese Society of Hepato-Biliary-Pancreatic Surgery. J Hepatobiliary Pancreat Sci (2012) 1.16
Laparoscopic adrenalectomy on a patient with primary aldosteronism during pregnancy. Endocr J (2006) 1.15
A novel molecular targeting compound as K-samII/FGF-R2 phosphorylation inhibitor, Ki23057, for Scirrhous gastric cancer. Gastroenterology (2006) 1.15
Gastric metastasis from renal cell carcinoma with gastrointestinal bleeding: a case report and review of the literature. Int Surg (2014) 1.14
Role of cyclooxygenase-2 in the carcinogenesis of gastrointestinal tract cancers: a review and report of personal experience. World J Gastroenterol (2006) 1.13
A meta-analysis of randomized controlled trials that compared laparoscopy-assisted and open distal gastrectomy for early gastric cancer. J Gastrointest Surg (2010) 1.13
Antitumor effect of trastuzumab for pancreatic cancer with high HER-2 expression and enhancement of effect by combined therapy with gemcitabine. Clin Cancer Res (2006) 1.12
Histone deacetylase inhibitor, trichostatin A, increases the chemosensitivity of anticancer drugs in gastric cancer cell lines. Oncol Rep (2006) 1.12
TIE2 gain-of-function mutation in a patient with pancreatic lymphangioma associated with blue rubber-bleb nevus syndrome: report of a case. Surg Today (2006) 1.12
A high preoperative neutrophil-to-lymphocyte ratio is associated with poor survival in patients with colorectal cancer. Anticancer Res (2013) 1.11
Feasibility and efficacy of preoperative chemotherapy with docetaxel, cisplatin and S-1 in gastric cancer patients with para-aortic lymph node metastases. Anticancer Drugs (2009) 1.10
Clinicopathological significance of platelet-derived growth factor (PDGF)-B and vascular endothelial growth factor-A expression, PDGF receptor-β phosphorylation, and microvessel density in gastric cancer. BMC Cancer (2010) 1.09
Aberrant expression of CDX2 is closely related to the intestinal metaplasia and MUC2 expression in intraductal papillary neoplasm of the liver in hepatolithiasis. Lab Invest (2004) 1.09
Lymphangioma of the lesser omentum associated with abdominal esophageal carcinoma: report of a case. Surg Today (2002) 1.09
Vitamin D receptor expression is associated with colon cancer in ulcerative colitis. Oncol Rep (2009) 1.08
Monoclonal antibodies to fibroblast growth factor receptor 2 effectively inhibit growth of gastric tumor xenografts. Clin Cancer Res (2010) 1.08
Decreased expression of the adhesion molecule desmoglein-2 is associated with diffuse-type gastric carcinoma. Eur J Cancer (2006) 1.08
CD133 is a useful surrogate marker for predicting chemosensitivity to neoadjuvant chemotherapy in breast cancer. PLoS One (2012) 1.08
Detection of sentinel and non-sentinel lymph node micrometastases by complete serial sectioning and immunohistochemical analysis for gastric cancer. J Exp Clin Cancer Res (2008) 1.08
HER2 overexpression correlates with survival after curative resection of pancreatic cancer. Cancer Sci (2009) 1.08
A meta-analysis of the short- and long-term results of randomized controlled trials that compared laparoscopy-assisted and conventional open surgery for rectal cancer. J Gastrointest Surg (2011) 1.07
Diffuse-type gastric carcinoma: progression, angiogenesis, and transforming growth factor beta signaling. J Natl Cancer Inst (2009) 1.07
Cancer stem cell-like SP cells have a high adhesion ability to the peritoneum in gastric carcinoma. Cancer Sci (2009) 1.06
Clinicopathologic and biological significance of kallikrein 6 overexpression in human gastric cancer. Clin Cancer Res (2005) 1.06
Thiazolidinedione, a peroxisome proliferator-activated receptor-gamma ligand, inhibits growth and metastasis of HT-29 human colon cancer cells through differentiation-promoting effects. Int J Oncol (2004) 1.05
Nerve plexus invasion in pancreatic cancer: spread patterns on histopathologic and embryological analyses. Pancreas (2008) 1.04
Angiotensin II activates MAP kinase and NF-kappaB through angiotensin II type I receptor in human pancreatic cancer cells. Int J Oncol (2004) 1.04
Impact of diabetes on recurrence of hepatocellular carcinoma after surgical treatment in patients with viral hepatitis. Am J Gastroenterol (2007) 1.04
Cancer-stromal interactions in scirrhous gastric carcinoma. Cancer Microenviron (2010) 1.03
Prognostic factors for gallbladder cancer in Japan. Ann Surg (2008) 1.03
Transforming growth factor β signaling inhibitor, SB-431542, induces maturation of dendritic cells and enhances anti-tumor activity. Oncol Rep (2010) 1.03
Is a lymph node detected by the dye-guided method a true sentinel node in gastric cancer? Clin Cancer Res (2004) 1.03
Characteristics and clinical relevance of postgastrectomy syndrome assessment scale (PGSAS)-45: newly developed integrated questionnaires for assessment of living status and quality of life in postgastrectomy patients. Gastric Cancer (2014) 1.03
Meta-analysis of laparoscopy-assisted and open distal gastrectomy for gastric cancer. J Surg Res (2010) 1.03
Reduction of 15-hydroxyprostaglandin dehydrogenase expression is an independent predictor of poor survival associated with enhanced cell proliferation in gastric adenocarcinoma. Cancer Sci (2009) 1.03
Prognostic value of preoperative inflammation-based prognostic scores in patients with stage IV colorectal cancer who undergo palliative resection of asymptomatic primary tumors. Anticancer Res (2013) 1.02
THBS4, a novel stromal molecule of diffuse-type gastric adenocarcinomas, identified by transcriptome-wide expression profiling. Mod Pathol (2011) 1.02