Published in Eur J Med Chem on April 14, 2009
Synthesis and evaluation of antiproliferative activity of substituted N-(9-oxo-9H-xanthen-4-yl)benzenesulfonamides. Tetrahedron Lett (2014) 0.75
2,4-Di-bromo-1,3-dihy-droxy-9H-xanthen-9-one. Acta Crystallogr Sect E Struct Rep Online (2013) 0.75
Transcription profiling of the Neurospora crassa response to a group of synthetic (thio)xanthones and a natural acetophenone. Genom Data (2015) 0.75
Regulation of MAPKs Signaling Contributes to the Growth Inhibition of 1,7-Dihydroxy-3,4-dimethoxyxanthone on Multidrug Resistance A549/Taxol Cells. Evid Based Complement Alternat Med (2016) 0.75
Chiral Derivatives of Xanthones: Investigation of the Effect of Enantioselectivity on Inhibition of Cyclooxygenases (COX-1 and COX-2) and Binding Interaction with Human Serum Albumin. Pharmaceuticals (Basel) (2017) 0.75
Crumbs, the Drosophila homologue of human CRB1/RP12, is essential for photoreceptor morphogenesis. Nature (2002) 3.22
Xanthones as inhibitors of growth of human cancer cell lines and their effects on the proliferation of human lymphocytes in vitro. Bioorg Med Chem (2002) 1.24
The viral polymerase inhibitor 2'-C-methylcytidine inhibits Norwalk virus replication and protects against norovirus-induced diarrhea and mortality in a mouse model. J Virol (2013) 1.05
Dihydroxyxanthones prenylated derivatives: synthesis, structure elucidation, and growth inhibitory activity on human tumor cell lines with improvement of selectivity for MCF-7. Bioorg Med Chem (2007) 1.01
The crystal and solution structures of glyceraldehyde-3-phosphate dehydrogenase reveal different quaternary structures. J Biol Chem (2006) 1.00
Anticancer activity evaluation of kuanoniamines A and C isolated from the marine sponge Oceanapia sagittaria, collected from the Gulf of Thailand. Mar Drugs (2007) 0.98
Unscripted narrative for affectively driven characters. IEEE Comput Graph Appl (2006) 0.98
Healthy apps: mobile devices for continuous monitoring and intervention. IEEE Pulse (2013) 0.98
Prevalence and transmission of hepatitis E virus in domestic swine populations in different European countries. BMC Res Notes (2012) 0.94
Antifungal activity evaluation of the constituents of Haliclona baeri and Haliclona cymaeformis, collected from the Gulf of Thailand. Mar Drugs (2007) 0.93
Heparan sulfate/heparin promotes transthyretin fibrillization through selective binding to a basic motif in the protein. Proc Natl Acad Sci U S A (2011) 0.91
Epstein-Barr virus in inflammatory bowel disease-correlation with different therapeutic regimens. Inflamm Bowel Dis (2013) 0.89
The binding of xanthone derivatives to transthyretin. Biochem Pharmacol (2005) 0.89
Effects of natural prenylated flavones in the phenotypical ER (+) MCF-7 and ER (-) MDA-MB-231 human breast cancer cells. Toxicol Lett (2005) 0.88
A generic crystallization-like model that describes the kinetics of amyloid fibril formation. J Biol Chem (2012) 0.88
The crystal structure of transthyretin in complex with diethylstilbestrol: a promising template for the design of amyloid inhibitors. J Biol Chem (2004) 0.88
Dual inhibitors of P-glycoprotein and tumor cell growth: (re)discovering thioxanthones. Biochem Pharmacol (2011) 0.87
Iodine atoms: a new molecular feature for the design of potent transthyretin fibrillogenesis inhibitors. PLoS One (2009) 0.87
Discovery of a new small-molecule inhibitor of p53-MDM2 interaction using a yeast-based approach. Biochem Pharmacol (2013) 0.87
Leptin as a marker of nutrition and cardiovascular risk in peritoneal dialysis patients. Adv Perit Dial (2002) 0.86
Sulfated small molecules targeting eBV in Burkitt lymphoma: from in silico screening to the evidence of in vitro effect on viral episomal DNA. Chem Biol Drug Des (2013) 0.85
Adult-onset leukodystrophy with axonal spheroids. J Neurol Sci (2010) 0.84
Virtual learning intervention to reduce bullying victimization in primary school: a controlled trial. J Child Psychol Psychiatry (2009) 0.83
New uses for old drugs: pharmacophore-based screening for the discovery of P-glycoprotein inhibitors. Chem Biol Drug Des (2011) 0.83
Insights into the in vitro antitumor mechanism of action of a new pyranoxanthone. Chem Biol Drug Des (2010) 0.82
Treatment of Akata EBV-positive cells with doxorubicin causes more EBV reactivation than treatment with etoposide. Chemotherapy (2011) 0.82
Functional characterization of Arabidopsis thaliana transthyretin-like protein. BMC Plant Biol (2010) 0.82
Synthesis of N-aryl-5-amino-4-cyanopyrazole derivatives as potent xanthine oxidase inhibitors. Eur J Med Chem (2007) 0.82
Structure and ligand-based design of P-glycoprotein inhibitors: a historical perspective. Curr Pharm Des (2012) 0.81
Antifungal activity of xanthones: evaluation of their effect on ergosterol biosynthesis by high-performance liquid chromatography. Chem Biol Drug Des (2011) 0.81
Psoralen analogues: synthesis, inhibitory activity of growth of human tumor cell lines and computational studies. Eur J Med Chem (2006) 0.81
Structure and assembly-disassembly properties of wild-type transthyretin amyloid protofibrils observed with atomic force microscopy. J Mol Recognit (2011) 0.81
Merodrimanes and other constituents from Talaromyces thailandiasis. J Nat Prod (2007) 0.80
Understanding water equilibration fundamentals as a step for rational protein crystallization. PLoS One (2008) 0.80
Synthesis of new heteroaryl and heteroannulated indoles from dehydrophenylalanines: Antitumor evaluation. Bioorg Med Chem (2008) 0.80
Solid-phase synthesis of 2'-hydroxychalcones. Effects on cell growth inhibition, cell cycle and apoptosis of human tumor cell lines. Bioorg Med Chem (2011) 0.80
Inhibition of protein kinase C by synthetic xanthone derivatives. Bioorg Med Chem (2003) 0.79
Prenylated derivatives of baicalein and 3,7-dihydroxyflavone: synthesis and study of their effects on tumor cell lines growth, cell cycle and apoptosis. Eur J Med Chem (2011) 0.79
Curcumin: A Natural Lead for Potential New Drug Candidates. Curr Med Chem (2015) 0.79
Synthesis of a natural chalcone and its prenyl analogs--evaluation of tumor cell growth-inhibitory activities, and effects on cell cycle and apoptosis. Chem Biodivers (2012) 0.79
Minimal change nephrotic syndrome after stem cell transplantation: a case report and literature review. J Med Case Rep (2007) 0.79
Clionasterol: a potent inhibitor of complement component C1. Planta Med (2003) 0.79
An unusual glucoside from Cleistanthus gracilis. Phytochemistry (2006) 0.79
Molecular and functional characterization of CBAVD-causing mutations located in CFTR nucleotide-binding domains. Cell Physiol Biochem (2008) 0.78
Structural basis for the protective role of sulfite against transthyretin amyloid formation. Biochim Biophys Acta (2006) 0.78
X-ray crystallographic studies of two transthyretin variants: further insights into amyloidogenesis. Acta Crystallogr D Biol Crystallogr (2005) 0.78
Structural insights into a zinc-dependent pathway leading to Leu55Pro transthyretin amyloid fibrils. Acta Crystallogr D Biol Crystallogr (2011) 0.78
Distinct annular oligomers captured along the assembly and disassembly pathways of transthyretin amyloid protofibrils. PLoS One (2012) 0.78
Evaluation of effect of triterpenes and limonoids on cell growth, cell cycle and apoptosis in human tumor cell line. Anticancer Agents Med Chem (2010) 0.78
Induction and activation of P-glycoprotein by dihydroxylated xanthones protect against the cytotoxicity of the P-glycoprotein substrate paraquat. Arch Toxicol (2014) 0.78
The binding of 2,4-dinitrophenol to wild-type and amyloidogenic transthyretin. Acta Crystallogr D Biol Crystallogr (2006) 0.77
Enantioseparation and chiral recognition mechanism of new chiral derivatives of xanthones on macrocyclic antibiotic stationary phases. J Chromatogr A (2012) 0.77
Synthesis and antitumor evaluation of benzopsoralen analogues. Chem Biodivers (2007) 0.77
Transthyretin is a metallopeptidase with an inducible active site. Biochem J (2012) 0.77
Synthesis of tetrahydronaphthalene lignan esters by intramolecular cyclization of ethyl p-azidophenyl-2-phenylalkanoates and evaluation of the growth inhibition of human tumor cell lines. J Med Chem (2011) 0.77
X-ray absorption spectroscopy reveals a substantial increase of sulfur oxidation in transthyretin (TTR) upon fibrillization. J Biol Chem (2003) 0.77
Improvement of the inhibitory effect of xanthones on NO production by encapsulation in PLGA nanocapsules. J Drug Target (2005) 0.76
Synthesis and in vivo modulatory activity of protein kinase C of xanthone derivatives. Bioorg Med Chem (2002) 0.76
Dipeptide crystals as excellent permselective materials: sequential exclusion of argon, nitrogen, and oxygen. Angew Chem Int Ed Engl (2010) 0.76
Inhibition of alpha, betaI, delta, eta, and zeta protein kinase C isoforms by xanthonolignoids. J Enzyme Inhib Med Chem (2003) 0.76
FH8--a small EF-hand protein from Fasciola hepatica. FEBS J (2010) 0.76
Α-mangostin and gambogic acid as potential inhibitors of the p53-MDM2 interaction revealed by a yeast approach. J Nat Prod (2013) 0.76
1-Hydr-oxy-3-(3-methyl-but-2-en-yloxy)xanthone. Acta Crystallogr Sect E Struct Rep Online (2009) 0.75
Lanostanes and friedolanostanes from the bark of Garcinia speciosa. Phytochemistry (2004) 0.75
Natural compounds with cell growth inhibitory activity in human tumor cell lines. Anticancer Agents Med Chem (2013) 0.75
First report of a norovirus outbreak associated with the variant Sydney 2012 in Portugal. J Infect Dev Ctries (2014) 0.75
Development of noncytotoxic PLGA nanoparticles to improve the effect of a new inhibitor of p53-MDM2 interaction. Int J Pharm (2013) 0.75
The epidemiology of blood-contaminated needlestick injuries among veterinarians in Portugal. J Agromedicine (2015) 0.75
Bioactive friedolanostanes and 11(10-->8)-abeolanostanes from the bark of Garcinia speciosa. J Nat Prod (2004) 0.75
Hemisynthetic secofriedelane triterpenes with inhibitory activity against the growth of human tumor cell lines in vitro. J Nat Prod (2004) 0.75
Cytotoxicities of xanthones and cinnamate esters from Hypericum hookerianum. Planta Med (2005) 0.75