Published in DNA Res on May 08, 2009
Extracellular matrix formation enhances the ability of Streptococcus pneumoniae to cause invasive disease. PLoS One (2011) 1.08
Biofilm formation in Streptococcus pneumoniae. Microb Biotechnol (2011) 0.98
The core promoter of the capsule operon of Streptococcus pneumoniae is necessary for colonization and invasive disease. Infect Immun (2013) 0.96
Sequence elements upstream of the core promoter are necessary for full transcription of the capsule gene operon in Streptococcus pneumoniae strain D39. Infect Immun (2015) 0.81
CpsR, a GntR family regulator, transcriptionally regulates capsular polysaccharide biosynthesis and governs bacterial virulence in Streptococcus pneumoniae. Sci Rep (2016) 0.76
Allelic Variation of the Capsule Promoter Diversifies Encapsulation and Virulence In Streptococcus pneumoniae. Sci Rep (2016) 0.75
ComE, an Essential Response Regulator, Negatively Regulates the Expression of the Capsular Polysaccharide Locus and Attenuates the Bacterial Virulence in Streptococcus pneumoniae. Front Microbiol (2017) 0.75
Genome of the bacterium Streptococcus pneumoniae strain R6. J Bacteriol (2001) 7.97
Discovery of a new capsular serotype (6C) within serogroup 6 of Streptococcus pneumoniae. J Clin Microbiol (2007) 7.44
Genetic analysis of the capsular biosynthetic locus from all 90 pneumococcal serotypes. PLoS Genet (2006) 6.43
The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease. Nat Rev Microbiol (2008) 5.98
Virulence control in group A Streptococcus by a two-component gene regulatory system: global expression profiling and in vivo infection modeling. Proc Natl Acad Sci U S A (2002) 3.83
Promoters responsive to DNA bending: a common theme in prokaryotic gene expression. Microbiol Rev (1994) 3.81
DBTBS: a database of transcriptional regulation in Bacillus subtilis containing upstream intergenic conservation information. Nucleic Acids Res (2007) 3.80
Genome sequence of Avery's virulent serotype 2 strain D39 of Streptococcus pneumoniae and comparison with that of unencapsulated laboratory strain R6. J Bacteriol (2006) 3.40
Predicted functions and linkage specificities of the products of the Streptococcus pneumoniae capsular biosynthetic loci. J Bacteriol (2007) 2.67
Illustration of pneumococcal polysaccharide capsule during adherence and invasion of epithelial cells. Infect Immun (2005) 2.60
Requirement for capsule in colonization by Streptococcus pneumoniae. Infect Immun (2001) 2.55
Microarray analysis of pneumococcal gene expression during invasive disease. Infect Immun (2004) 2.38
The Lactococcus lactis CodY regulon: identification of a conserved cis-regulatory element. J Biol Chem (2005) 2.11
Catabolite control protein A (CcpA) contributes to virulence and regulation of sugar metabolism in Streptococcus pneumoniae. J Bacteriol (2005) 2.09
A direct link between carbohydrate utilization and virulence in the major human pathogen group A Streptococcus. Proc Natl Acad Sci U S A (2008) 2.02
CovS/CovR of group B streptococcus: a two-component global regulatory system involved in virulence. Mol Microbiol (2004) 1.94
Recent trends on the molecular biology of pneumococcal capsules, lytic enzymes, and bacteriophage. FEMS Microbiol Rev (2004) 1.92
The genes encoding virulence-associated proteins and the capsule of Streptococcus pneumoniae are upregulated and differentially expressed in vivo. Microbiology (2002) 1.75
Role of RegM, a homologue of the catabolite repressor protein CcpA, in the virulence of Streptococcus pneumoniae. Infect Immun (2002) 1.74
Factors determining the appearance of glucose in upper and lower respiratory tract secretions. Intensive Care Med (2003) 1.71
DNA analysis servers: plot.it, bend.it, model.it and IS. Nucleic Acids Res (2003) 1.70
Molecular organization of the genes required for the synthesis of type 1 capsular polysaccharide of Streptococcus pneumoniae: formation of binary encapsulated pneumococci and identification of cryptic dTDP-rhamnose biosynthesis genes. Mol Microbiol (1997) 1.69
Transient association of an alternative sigma factor, ComX, with RNA polymerase during the period of competence for genetic transformation in Streptococcus pneumoniae. J Bacteriol (2003) 1.68
Identification of binding sites for the group A streptococcal global regulator CovR. Mol Microbiol (2002) 1.65
Characterization of biofilm matrix, degradation by DNase treatment and evidence of capsule downregulation in Streptococcus pneumoniae clinical isolates. BMC Microbiol (2008) 1.64
CodY of Streptococcus pneumoniae: link between nutritional gene regulation and colonization. J Bacteriol (2007) 1.64
Hyperglycemia and cystic fibrosis alter respiratory fluid glucose concentrations estimated by breath condensate analysis. J Appl Physiol (1985) (2007) 1.62
Repeated extragenic sequences in prokaryotic genomes: a proposal for the origin and dynamics of the RUP element in Streptococcus pneumoniae. Microbiology (1999) 1.62
Differential expression of key pneumococcal virulence genes in vivo. Microbiology (2006) 1.50
Regulation of glutamine and glutamate metabolism by GlnR and GlnA in Streptococcus pneumoniae. J Biol Chem (2006) 1.50
Regulation of iron transport in Streptococcus pneumoniae by RitR, an orphan response regulator. J Bacteriol (2004) 1.34
The maltose/maltodextrin regulon of Streptococcus pneumoniae. Differential promoter regulation by the transcriptional repressor MalR. J Biol Chem (1997) 1.31
Pneumococcal virulence gene expression and host cytokine profiles during pathogenesis of invasive disease. Infect Immun (2007) 1.24
Tts, a processive beta-glucosyltransferase of Streptococcus pneumoniae, directs the synthesis of the branched type 37 capsular polysaccharide in Pneumococcus and other gram-positive species. J Biol Chem (2001) 1.18
Genetic bases and medical relevance of capsular polysaccharide biosynthesis in pathogenic streptococci. Curr Mol Med (2001) 1.11
Vancomycin stress response in a sensitive and a tolerant strain of Streptococcus pneumoniae. J Bacteriol (2005) 1.04
The orphan response regulator CovR: a globally negative modulator of virulence in Streptococcus suis serotype 2. J Bacteriol (2009) 0.99
In vitro expression of the first capsule gene of Streptococcus pneumoniae, cpsA, is associated with serotype-specific colonization prevalence and invasiveness. Microbiology (2007) 0.98
Gene expression profiling of the response of Streptococcus pneumoniae to penicillin. J Antimicrob Chemother (2007) 0.98
CopY-like copper inducible repressors are putative 'winged helix' proteins. Biometals (2006) 0.93
Genome analysis of Escherichia coli promoter sequences evidences that DNA static curvature plays a more important role in gene transcription than has previously been anticipated. Genomics (2006) 0.87
[Regulation of nitrogen metabolism in gram-positive bacteria]. Mol Biol (Mosk) (2006) 0.86
Pneumococcus: the sugar-coated bacteria. Int Microbiol (2006) 0.85
Cop-like operon: structure and organization in species of the Lactobacillale order. Biol Res (2006) 0.84
Comparative analysis of growth-phase-dependent gene expression in virulent and avirulent Streptococcus pneumoniae using a high-density DNA microarray. Mol Cells (2006) 0.80
Biofilm formation by Streptococcus pneumoniae: role of choline, extracellular DNA, and capsular polysaccharide in microbial accretion. J Bacteriol (2006) 2.42
Recent trends on the molecular biology of pneumococcal capsules, lytic enzymes, and bacteriophage. FEMS Microbiol Rev (2004) 1.92
Phage lytic enzymes as therapy for antibiotic-resistant Streptococcus pneumoniae infection in a murine sepsis model. J Antimicrob Chemother (2003) 1.70
Molecular peculiarities of the lytA gene isolated from clinical pneumococcal strains that are bile insoluble. J Clin Microbiol (2002) 1.34
Characteristic signatures of the lytA gene provide a basis for rapid and reliable diagnosis of Streptococcus pneumoniae infections. J Clin Microbiol (2006) 1.27
Pneumococcal biofilms. Int Microbiol (2009) 1.19
Genome organization and molecular analysis of the temperate bacteriophage MM1 of Streptococcus pneumoniae. J Bacteriol (2003) 1.16
Genome annotation and intraviral interactome for the Streptococcus pneumoniae virulent phage Dp-1. J Bacteriol (2010) 1.12
Versatility of the capsular genes during biofilm formation by Streptococcus pneumoniae. Environ Microbiol (2009) 1.07
Genomic organization and molecular analysis of the inducible prophage EJ-1, a mosaic myovirus from an atypical pneumococcus. Virology (2004) 1.06
Isolation and characterization of a new plasmid pSpnP1 from a multidrug-resistant clone of Streptococcus pneumoniae. Plasmid (2007) 1.05
Comparative genomic analysis of ten Streptococcus pneumoniae temperate bacteriophages. J Bacteriol (2009) 1.04
Nasopharyngeal colonization and invasive disease are enhanced by the cell wall hydrolases LytB and LytC of Streptococcus pneumoniae. PLoS One (2011) 1.00
Molecular characterization of disease-associated streptococci of the mitis group that are optochin susceptible. J Clin Microbiol (2006) 0.99
Biofilm formation in Streptococcus pneumoniae. Microb Biotechnol (2011) 0.98
Development of a prophage typing system and analysis of prophage carriage in Streptococcus pneumoniae. Appl Environ Microbiol (2009) 0.98
Biochemical characterization of the pneumococcal glucose 1-phosphate uridylyltransferase (GalU) essential for capsule biosynthesis. Curr Microbiol (2005) 0.98
Biofilm formation avoids complement immunity and phagocytosis of Streptococcus pneumoniae. Infect Immun (2013) 0.98
Two new crystal forms of the choline-binding domain of the major pneumococcal autolysin: insights into the dynamics of the active homodimer. J Mol Biol (2002) 0.98
In vitro destruction of Streptococcus pneumoniae biofilms with bacterial and phage peptidoglycan hydrolases. Antimicrob Agents Chemother (2011) 0.96
Improving the lethal effect of cpl-7, a pneumococcal phage lysozyme with broad bactericidal activity, by inverting the net charge of its cell wall-binding module. Antimicrob Agents Chemother (2013) 0.94
Characterization of LytA-like N-acetylmuramoyl-L-alanine amidases from two new Streptococcus mitis bacteriophages provides insights into the properties of the major pneumococcal autolysin. J Bacteriol (2004) 0.92
Insight into the composition of the intercellular matrix of Streptococcus pneumoniae biofilms. Environ Microbiol (2012) 0.91
In vitro bactericidal activity of the antiprotozoal drug miltefosine against Streptococcus pneumoniae and other pathogenic streptococci. Antimicrob Agents Chemother (2007) 0.90
Cpl-7, a lysozyme encoded by a pneumococcal bacteriophage with a novel cell wall-binding motif. J Biol Chem (2010) 0.88
Thermal stability of Cpl-7 endolysin from the streptococcus pneumoniae bacteriophage Cp-7; cell wall-targeting of its CW_7 motifs. PLoS One (2012) 0.87
Skl, a novel choline-binding N-acetylmuramoyl-L-alanine amidase of Streptococcus mitis SK137 containing a CHAP domain. FEBS Lett (2006) 0.87
Key role of amino acid residues in the dimerization and catalytic activation of the autolysin LytA, an important virulence factor in Streptococcus pneumoniae. J Biol Chem (2007) 0.85
In vitro interactions of LytA, the major pneumococcal autolysin, with two bacteriophage lytic enzymes (Cpl-1 and Pal), cefotaxime and moxifloxacin against antibiotic-susceptible and -resistant Streptococcus pneumoniae strains. J Antimicrob Chemother (2007) 0.84
Peculiarities of the DNA of MM1, a temperate phage of Streptococcus pneumoniae. Int Microbiol (2004) 0.84
Ofloxacin-like antibiotics inhibit pneumococcal cell wall-degrading virulence factors. J Biol Chem (2005) 0.84
Characterization of invasive Pneumococci of serogroup 6 from adults in Barcelona, Spain, in 1994 to 2008. J Clin Microbiol (2011) 0.83
Enhanced in vivo activity of cefditoren in pre-immunized mice against penicillin-resistant S. pneumoniae (serotypes 6B, 19F and 23F) in a sepsis model. PLoS One (2010) 0.83
Allelic variation of polymorphic locus lytB, encoding a choline-binding protein, from streptococci of the mitis group. Appl Environ Microbiol (2005) 0.83
Spread of Streptococcus pneumoniae serotype 8-ST63 multidrug-resistant recombinant Clone, Spain. Emerg Infect Dis (2014) 0.82
Pneumococcal LytA autolysin, a potent therapeutic agent in experimental peritonitis-sepsis caused by highly beta-lactam-resistant Streptococcus pneumoniae. Antimicrob Agents Chemother (2007) 0.82
PHACOS, a functionalized bacterial polyester with bactericidal activity against methicillin-resistant Staphylococcus aureus. Biomaterials (2013) 0.81
Macrolides and β-lactam antibiotics enhance C3b deposition on the surface of multidrug-resistant Streptococcus pneumoniae strains by a LytA autolysin-dependent mechanism. Antimicrob Agents Chemother (2012) 0.81
Cefditoren and ceftriaxone enhance complement-mediated immunity in the presence of specific antibodies against antibiotic-resistant pneumococcal strains. PLoS One (2012) 0.80
In vitro biofilm formation by Streptococcus pneumoniae as a predictor of post-vaccination emerging serotypes colonizing the human nasopharynx. Environ Microbiol (2014) 0.80
Implications of physiological studies based on genomic sequences: Streptococcus pneumoniae TIGR4 synthesizes a functional LytC lysozyme. J Bacteriol (2005) 0.79
Disposable amperometric magnetoimmunosensors for the specific detection of Streptococcus pneumoniae. Biosens Bioelectron (2010) 0.79
Vancomycin tolerance in Gram-positive cocci. Environ Microbiol Rep (2011) 0.78
The galU gene expression in Streptococcus pneumoniae. FEMS Microbiol Lett (2012) 0.77
Evidence of localized prophage-host recombination in the lytA gene, encoding the major pneumococcal autolysin. J Bacteriol (2010) 0.76
Mutations in the tacF gene of clinical strains and laboratory transformants of Streptococcus pneumoniae: impact on choline auxotrophy and growth rate. J Bacteriol (2008) 0.75
Development of amperometric magnetogenosensors coupled to asymmetric PCR for the specific detection of Streptococcus pneumoniae. Anal Bioanal Chem (2011) 0.75
Theoretical study of the complex-forming CH + H2 --> CH2 + H reaction. J Phys Chem A (2006) 0.75
Dissemination of an erythromycin-resistant penicillin-nonsusceptible Streptococcus pneumoniae Poland(6B)-20 clone in Argentina. Microb Drug Resist (2010) 0.75
Can quasiclassical trajectory calculations reproduce the extreme kinetic isotope effect observed in the muonic isotopologues of the H + H2 reaction? J Chem Phys (2011) 0.75
Comparative efficacy of novobiocin and amoxicillin in experimental sepsis caused by beta-lactam-susceptible and highly resistant pneumococci. Int J Antimicrob Agents (2010) 0.75