Published in Chim Oggi on September 01, 2008
Organic cation transporters. Rev Physiol Biochem Pharmacol (2003) 1.77
Allosteric modifiers of neuronal nicotinic acetylcholine receptors: new methods, new opportunities. Med Res Rev (2007) 1.28
Development and characterization of immobilized human organic anion transporter-based liquid chromatographic stationary phase: hOAT1 and hOAT2. J Chromatogr B Analyt Technol Biomed Life Sci (2007) 1.17
Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa). J Pharmacol Exp Ther (1998) 1.11
Development of immobilized membrane-based affinity columns for use in the online characterization of membrane bound proteins and for targeted affinity isolations. Anal Chim Acta (2005) 1.07
The synthesis and initial characterization of an immobilized purinergic receptor (P2Y1) liquid chromatography stationary phase for online screening. Anal Biochem (2007) 1.07
On-line screening of conformationally constrained nicotines and anabasines for agonist activity at the alpha3beta4- and alpha4beta2-nicotinic acetylcholine receptors using immobilized receptor-based liquid chromatographic stationary phases. J Chromatogr B Analyt Technol Biomed Life Sci (2004) 1.04
Development and characterization of an immobilized human organic cation transporter based liquid chromatographic stationary phase. J Chromatogr B Analyt Technol Biomed Life Sci (2005) 1.02
Syntheses of immobilized G protein-coupled receptor chromatographic stationary phases: characterization of immobilized mu and kappa opioid receptors. Anal Chem (2003) 1.02
Pharmacophore modelling of stereoselective binding to the human organic cation transporter (hOCT1). Br J Pharmacol (2007) 1.00
G-protein-coupled receptor chromatographic stationary phases. 2. Ligand-induced conformational mobility in an immobilized beta2-adrenergic receptor. Anal Chem (2004) 1.00
Interaction of noncompetitive inhibitors with the alpha3beta2 nicotinic acetylcholine receptor investigated by affinity chromatography and molecular docking. J Med Chem (2007) 0.98
Enantioselective binding to the human organic cation transporter-1 (hOCT1) determined using an immobilized hOCT1 liquid chromatographic stationary phase. Chirality (2005) 0.95
Identification of P-glycoprotein substrates using open tubular chromatography on an immobilized P-glycoprotein column: Comparison of chromatographic results with Caco-2 permeability. Anal Chim Acta (2006) 0.95
Initial synthesis and characterization of an alpha7 nicotinic receptor cellular membrane affinity chromatography column: effect of receptor subtype and cell type. Anal Chem (2007) 0.94
Screening of tobacco smoke condensate for nicotinic acetylcholine receptor ligands using cellular membrane affinity chromatography columns and missing peak chromatography. J Pharm Biomed Anal (2007) 0.94
Multiple receptor liquid chromatographic stationary phases: the co-immobilization of nicotinic receptors, gamma-amino-butyric acid receptors, and N-methyl D-aspartate receptors. Pharm Res (2002) 0.88
Exploring enantiospecific ligand-protein interactions using cellular membrane affinity chromatography: chiral recognition as a dynamic process. J Chromatogr B Analyt Technol Biomed Life Sci (2008) 0.84
Stereochemistry of an agonist determines coupling preference of beta2-adrenoceptor to different G proteins in cardiomyocytes. Mol Pharmacol (2008) 1.78
Comparative molecular field analysis of the binding of the stereoisomers of fenoterol and fenoterol derivatives to the beta2 adrenergic receptor. J Med Chem (2007) 1.77
(R,S)-Ketamine metabolites (R,S)-norketamine and (2S,6S)-hydroxynorketamine increase the mammalian target of rapamycin function. Anesthesiology (2014) 1.76
Relationship of ketamine's plasma metabolites with response, diagnosis, and side effects in major depression. Biol Psychiatry (2012) 1.47
The preparation and development of cellular membrane affinity chromatography columns. Nat Protoc (2009) 1.34
Sub-anesthetic concentrations of (R,S)-ketamine metabolites inhibit acetylcholine-evoked currents in α7 nicotinic acetylcholine receptors. Eur J Pharmacol (2012) 1.32
Intensive therapy with growth factor support for patients with Ewing tumor metastatic at diagnosis: Pediatric Oncology Group/Children's Cancer Group Phase II Study 9457--a report from the Children's Oncology Group. J Clin Oncol (2006) 1.30
Allosteric modifiers of neuronal nicotinic acetylcholine receptors: new methods, new opportunities. Med Res Rev (2007) 1.28
Stereoselective and regiospecific hydroxylation of ketamine and norketamine. Xenobiotica (2012) 1.15
Enantioselective separation and online affinity chromatographic characterization of R,R- and S,S-fenoterol. Chirality (2006) 1.14
Rapid analysis of the interactions between drugs and human serum albumin (HSA) using high-performance affinity chromatography (HPAC). J Chromatogr B Analyt Technol Biomed Life Sci (2008) 1.10
Comparative molecular field analysis of fenoterol derivatives: A platform towards highly selective and effective beta(2)-adrenergic receptor agonists. Bioorg Med Chem (2009) 1.09
Development of immobilized membrane-based affinity columns for use in the online characterization of membrane bound proteins and for targeted affinity isolations. Anal Chim Acta (2005) 1.07
The synthesis and initial characterization of an immobilized purinergic receptor (P2Y1) liquid chromatography stationary phase for online screening. Anal Biochem (2007) 1.07
Simultaneous population pharmacokinetic modelling of ketamine and three major metabolites in patients with treatment-resistant bipolar depression. Br J Clin Pharmacol (2012) 1.06
Pharmacodynamic profiles of ketamine (R)- and (S)- with 5-day inpatient infusion for the treatment of complex regional pain syndrome. Pain Physician (2010) 1.05
On-line screening of conformationally constrained nicotines and anabasines for agonist activity at the alpha3beta4- and alpha4beta2-nicotinic acetylcholine receptors using immobilized receptor-based liquid chromatographic stationary phases. J Chromatogr B Analyt Technol Biomed Life Sci (2004) 1.04
Nicotinic acetylcholine receptor antagonists alter the function and expression of serine racemase in PC-12 and 1321N1 cells. Cell Signal (2013) 1.02
Syntheses of immobilized G protein-coupled receptor chromatographic stationary phases: characterization of immobilized mu and kappa opioid receptors. Anal Chem (2003) 1.02
Initial synthesis and characterization of an immobilized heat shock protein 90 column for online determination of binding affinities. Anal Biochem (2007) 1.01
Conformational mobility of immobilized alpha3beta2, alpha3beta4, alpha4beta2, and alpha4beta4 nicotinic acetylcholine receptors. Anal Chem (2005) 1.00
G-protein-coupled receptor chromatographic stationary phases. 2. Ligand-induced conformational mobility in an immobilized beta2-adrenergic receptor. Anal Chem (2004) 1.00
Interaction of noncompetitive inhibitors with the alpha3beta2 nicotinic acetylcholine receptor investigated by affinity chromatography and molecular docking. J Med Chem (2007) 0.98
Development and characterization of an open tubular column containing immobilized P-glycoprotein for rapid on-line screening for P-glycoprotein substrates. J Chromatogr B Analyt Technol Biomed Life Sci (2004) 0.97
Breast cancer resistance protein (BCRP/ABCG2) localises to the nucleus in glioblastoma multiforme cells. Xenobiotica (2012) 0.97
Enantioselective interactions of dextromethorphan and levomethorphan with the alpha 3 beta 4-nicotinic acetylcholine receptor: comparison of chromatographic and functional data. J Chromatogr B Analyt Technol Biomed Life Sci (2003) 0.96
Effects of protein calorie malnutrition on the pharmacokinetics of ketamine in rats. Drug Metab Dispos (2004) 0.95
Identification of P-glycoprotein substrates using open tubular chromatography on an immobilized P-glycoprotein column: Comparison of chromatographic results with Caco-2 permeability. Anal Chim Acta (2006) 0.95
Screening of tobacco smoke condensate for nicotinic acetylcholine receptor ligands using cellular membrane affinity chromatography columns and missing peak chromatography. J Pharm Biomed Anal (2007) 0.94
Initial synthesis and characterization of an alpha7 nicotinic receptor cellular membrane affinity chromatography column: effect of receptor subtype and cell type. Anal Chem (2007) 0.94
A validated liquid chromatography method for the simultaneous determination of vitamins A and E in human plasma. J Pharm Biomed Anal (2007) 0.93
D-serine plasma concentration is a potential biomarker of (R,S)-ketamine antidepressant response in subjects with treatment-resistant depression. Psychopharmacology (Berl) (2014) 0.93
Conformational mobility of immobilized proteins. J Pharm Biomed Anal (2006) 0.91
Gabapentin and (S)-pregabalin decrease intracellular D-serine concentrations in PC-12 cells. Neurosci Lett (2012) 0.91
Frontal affinity chromatography-mass spectrometry useful for characterization of new ligands for GPR17 receptor. J Med Chem (2010) 0.90
Immobilized receptor- and transporter-based liquid chromatographic phases for on-line pharmacological and biochemical studies: a mini-review. J Chromatogr B Analyt Technol Biomed Life Sci (2002) 0.90
What is hydroxynorketamine and what can it bring to neurotherapeutics? Expert Rev Neurother (2014) 0.90
HPLC-electrospray mass spectrometric assay for the determination of (R,R)-fenoterol in rat plasma. J Pharm Biomed Anal (2008) 0.89
Identification and characterization of estrogen receptor-related receptor alpha and gamma in human glioma and astrocytoma cells. Mol Cell Endocrinol (2009) 0.89
Enantioselective pharmacokinetics of (R)- and (S)-ketamine after a 5-day infusion in patients with complex regional pain syndrome. Chirality (2010) 0.88
Multiple receptor liquid chromatographic stationary phases: the co-immobilization of nicotinic receptors, gamma-amino-butyric acid receptors, and N-methyl D-aspartate receptors. Pharm Res (2002) 0.88
Interaction of bupropion with muscle-type nicotinic acetylcholine receptors in different conformational states. Biochemistry (2009) 0.88
Uniformly-sized, molecularly imprinted polymers for nicotine by precipitation polymerization. J Chromatogr A (2006) 0.86
Capillary electrophoresis-laser-induced fluorescence (CE-LIF) assay for measurement of intracellular D-serine and serine racemase activity. Anal Biochem (2011) 0.86
The effect of stereochemistry on the thermodynamic characteristics of the binding of fenoterol stereoisomers to the beta(2)-adrenoceptor. Biochem Pharmacol (2010) 0.86
Thermodynamics and docking of agonists to the β(2)-adrenoceptor determined using [(3)H](R,R')-4-methoxyfenoterol as the marker ligand. Mol Pharmacol (2012) 0.86
The development and characterization of protein-based stationary phases for studying drug-protein and protein-protein interactions. J Chromatogr A (2011) 0.86
Immobilized nicotinic receptor stationary phases: going with the flow in high-throughput screening and pharmacological studies. J Pharm Biomed Anal (2003) 0.85
Exploring enantiospecific ligand-protein interactions using cellular membrane affinity chromatography: chiral recognition as a dynamic process. J Chromatogr B Analyt Technol Biomed Life Sci (2008) 0.84
Tricyclic antidepressants and mecamylamine bind to different sites in the human alpha4beta2 nicotinic receptor ion channel. Int J Biochem Cell Biol (2010) 0.84
Multidimensional on-line screening for ligands to the alpha3beta4 neuronal nicotinic acetylcholine receptor using an immobilized nicotinic receptor liquid chromatographic stationary phase. J Chromatogr B Analyt Technol Biomed Life Sci (2002) 0.84
Determination of the enantiomers of ketamine and norketamine in human plasma by enantioselective liquid chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci (2003) 0.84
Quantitative determination of fenoterol and fenoterol derivatives in rat plasma using on-line immunoextraction and liquid chromatography/mass spectrometry. J Chromatogr A (2008) 0.84
The effect of grapefruit juice and seville orange juice on the pharmacokinetics of dextromethorphan: the role of gut CYP3A and P-glycoprotein. Life Sci (2002) 0.84
Simultaneous determination of buprenorphine, norbuprenorphine and the enantiomers of methadone and its metabolite (EDDP) in human plasma by liquid chromatography/mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci (2006) 0.83
Cannabinoid receptor activation correlates with the proapoptotic action of the β2-adrenergic agonist (R,R')-4-methoxy-1-naphthylfenoterol in HepG2 hepatocarcinoma cells. J Pharmacol Exp Ther (2012) 0.83
Development and characterization of an immobilized enzyme reactor (IMER) based on human glyceraldehyde-3-phosphate dehydrogenase for on-line enzymatic studies. J Chromatogr A (2005) 0.82
HPLC-atmospheric pressure chemical ionization mass spectrometric method for enantioselective determination of R,S-propranolol and R,S-hyoscyamine in human plasma. J Chromatogr B Analyt Technol Biomed Life Sci (2007) 0.82
Synthesis of Tritium Labeled (R,R)-4-Methoxyfenoterol. J Labelled Comp Radiopharm (2010) 0.82
The synthesis and initial characterization of an immobilized DNA unwinding element binding (DUE-B) protein chromatographic stationary phase. J Chromatogr B Analyt Technol Biomed Life Sci (2005) 0.82
Genotype/phenotype comparisons: a probe for the effect of disease progression on drug metabolism. Curr Opin Drug Discov Devel (2002) 0.81
Advances in translational neuropathic research: example of enantioselective pharmacokinetic-pharmacodynamic modeling of ketamine-induced pain relief in complex regional pain syndrome. Curr Pain Headache Rep (2011) 0.81
Development and characterization of an immobilized enzyme reactor based on glyceraldehyde-3-phosphate dehydrogenase for on-line enzymatic studies. J Chromatogr A (2003) 0.81
The rapid and direct determination of ATPase activity by ion exchange chromatography and the application to the activity of heat shock protein-90. J Pharm Biomed Anal (2012) 0.81
Interaction of 18-methoxycoronaridine with nicotinic acetylcholine receptors in different conformational states. Biochim Biophys Acta (2010) 0.80
Structure-bias relationships for fenoterol stereoisomers in six molecular and cellular assays at the β2-adrenoceptor. Naunyn Schmiedebergs Arch Pharmacol (2014) 0.80
Immobilized enzyme reactors based upon the flavoenzymes monoamine oxidase A and B. J Chromatogr B Analyt Technol Biomed Life Sci (2004) 0.80
Determination of total and free concentrations of the enantiomers of methadone and its metabolite (2-ethylidene-1,5-dimethyl-3,3-diphenyl-pyrrolidine) in human plasma by enantioselective liquid chromatography with mass spectrometric detection. J Chromatogr A (2005) 0.79
Molecular interactions between fenoterol stereoisomers and derivatives and the β₂-adrenergic receptor binding site studied by docking and molecular dynamics simulations. J Mol Model (2013) 0.79
A novel class of allosteric modulators of AMPA/Kainate receptors. Bioorg Med Chem Lett (2008) 0.79
Enantioselective liquid chromatography-mass spectrometry assay for the determination of ifosfamide and identification of the N-dechloroethylated metabolites of ifosfamide in human plasma. J Pharm Biomed Anal (2007) 0.79
The relationship between a urinary cachectic factor and weight loss in advanced cancer patients. Cancer Invest (2004) 0.79
Determination of free and protein-bound glutathione in HepG2 cells using capillary electrophoresis with laser-induced fluorescence detection. J Chromatogr A (2008) 0.79
Interaction of fenoterol stereoisomers with β2-adrenoceptor-G sα fusion proteins: antagonist and agonist competition binding. Naunyn Schmiedebergs Arch Pharmacol (2015) 0.78
The enantioselective determination of chlorpheniramine and its major metabolites in human plasma using chiral chromatography on a beta-cyclodextrin chiral stationary phase and mass spectrometric detection. J Pharm Biomed Anal (2002) 0.78
Synthesis and characterization of a cellular membrane affinity chromatography column containing histamine 1 and P2Y(1) receptors: a multiple G-protein coupled receptor column. J Pharm Biomed Anal (2009) 0.78
Synthesis of an immobilized Bombyx mori pheromone-binding protein liquid chromatography stationary phase. Talanta (2006) 0.78
Role of chiral chromatography in therapeutic drug monitoring and in clinical and forensic toxicology. Ther Drug Monit (2002) 0.78
Finding time for allosteric interactions. Nat Biotechnol (2004) 0.77
On-line synthesis utilizing immobilized enzyme reactors based upon immobilized dopamine beta-hydroxylase. J Chromatogr B Analyt Technol Biomed Life Sci (2002) 0.77
Verapamil metabolites: potential P-glycoprotein-mediated multidrug resistance reversal agents. Can J Physiol Pharmacol (2003) 0.77
Effect of fenoterol stereochemistry on the β2 adrenergic receptor system: ligand-directed chiral recognition. Chirality (2011) 0.77
Simultaneous analysis of liposomal doxorubicin and doxorubicin using capillary electrophoresis and laser induced fluorescence. J Pharm Biomed Anal (2009) 0.76
Interaction of ibogaine with human alpha3beta4-nicotinic acetylcholine receptors in different conformational states. Int J Biochem Cell Biol (2010) 0.76
The stereoselective sulfate conjugation of 4'-methoxyfenoterol stereoisomers by sulfotransferase enzymes. Chirality (2012) 0.76
Qualitative assessment of IC50 values of inhibitors of the neuronal nicotinic acetylcholine receptor using a single chromatographic experiment and multivariate cluster analysis. J Chromatogr B Analyt Technol Biomed Life Sci (2005) 0.76
Ketamine infusion successful in some patients. Pain Physician (2010) 0.75
Binding study of desethyloxybutynin using high-performance frontal analysis method. J Chromatogr B Analyt Technol Biomed Life Sci (2002) 0.75
Plasma protein binding study of oxybutynin by high-performance frontal analysis. J Chromatogr B Analyt Technol Biomed Life Sci (2002) 0.75
The roles of CYP2D6 and stereoselectivity in the clinical pharmacokinetics of chlorpheniramine. Br J Clin Pharmacol (2002) 0.75
The covalent immobilization of microsomal uridine diphospho-glucuronosyltransferase (UDPGT): initial synthesis and characterization of an UDPGT immobilized enzyme reactor for the on-line study of glucuronidation. J Chromatogr B Analyt Technol Biomed Life Sci (2005) 0.75
Preface. J Pharm Biomed Anal (2017) 0.75
On-line drug metabolism in capillary electrophoresis. 1. Glucuronidation using rat liver microsomes. Anal Chem (2006) 0.75