Published in Curr Cancer Drug Targets on May 01, 2009
Let-7 modulates acquired resistance of ovarian cancer to Taxanes via IMP-1-mediated stabilization of multidrug resistance 1. Int J Cancer (2011) 1.27
Transient receptor potential channel TRPC5 is essential for P-glycoprotein induction in drug-resistant cancer cells. Proc Natl Acad Sci U S A (2012) 1.00
Beyond DNA binding - a review of the potential mechanisms mediating quinacrine's therapeutic activities in parasitic infections, inflammation, and cancers. Cell Commun Signal (2011) 0.99
Discovery of 7-hydroxy-6-methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan (BNC105), a tubulin polymerization inhibitor with potent antiproliferative and tumor vascular disrupting properties. J Med Chem (2011) 0.98
ABC transporters and their role in nucleoside and nucleotide drug resistance. Biochem Pharmacol (2012) 0.98
Granulocyte colony-stimulating factor receptor signalling via Janus kinase 2/signal transducer and activator of transcription 3 in ovarian cancer. Br J Cancer (2013) 0.93
Effects of the CK2 inhibitors CX-4945 and CX-5011 on drug-resistant cells. PLoS One (2012) 0.88
Preparation and characterization of stable nanoliposomal formulation of fluoxetine as a potential adjuvant therapy for drug-resistant tumors. Iran J Pharm Res (2014) 0.87
Astragalus polysaccharides can regulate cytokine and P-glycoprotein expression in H22 tumor-bearing mice. World J Gastroenterol (2012) 0.87
TALEN-mediated Nanog disruption results in less invasiveness, more chemosensitivity and reversal of EMT in Hela cells. Oncotarget (2014) 0.86
EAPP: gatekeeper at the crossroad of apoptosis and p21-mediated cell-cycle arrest. Oncogene (2011) 0.85
Effects of Astragalus polysaccharides on P-glycoprotein efflux pump function and protein expression in H22 hepatoma cells in vitro. BMC Complement Altern Med (2012) 0.85
The Human Cathelicidin Antimicrobial Peptide LL-37 and Mimics are Potential Anticancer Drugs. Front Oncol (2015) 0.82
Functional study of the novel multidrug resistance gene HA117 and its comparison to multidrug resistance gene 1. J Exp Clin Cancer Res (2010) 0.82
Inhibition of transient receptor potential channel 5 reverses 5-Fluorouracil resistance in human colorectal cancer cells. J Biol Chem (2014) 0.80
HDAC inhibitor-induced drug resistance involving ATP-binding cassette transporters (Review). Oncol Lett (2014) 0.79
Evading Pgp activity in drug-resistant cancer cells: a structural and functional study of antitubulin furan metotica compounds. Mol Cancer Ther (2012) 0.78
Targeting of multidrug-resistant human ovarian carcinoma cells with anti-P-glycoprotein antibody conjugates. Macromol Biosci (2012) 0.78
Interindividual epigenetic variation in ABCB1 promoter and its relationship with ABCB1 expression and function in healthy Chinese subjects. Br J Clin Pharmacol (2015) 0.77
NVP-TAE684 reverses multidrug resistance (MDR) in human osteosarcoma by inhibiting P-glycoprotein (PGP1) function. Br J Pharmacol (2016) 0.77
18FDG, [18F]FLT, [18F]FAZA, and 11C-methionine are suitable tracers for the diagnosis and in vivo follow-up of the efficacy of chemotherapy by miniPET in both multidrug resistant and sensitive human gynecologic tumor xenografts. Biomed Res Int (2014) 0.77
Fas signaling promotes chemoresistance in gastrointestinal cancer by up-regulating P-glycoprotein. Oncotarget (2014) 0.77
Genome-wide profiles of methylation, microRNAs, and gene expression in chemoresistant breast cancer. Sci Rep (2016) 0.76
Induction of Hsp70 in tumor cells treated with inhibitors of the Hsp90 activity: A predictive marker and promising target for radiosensitization. PLoS One (2017) 0.75
Rheumatoid Arthritis Disease Activity Is Determinant for ABCB1 and ABCG2 Drug-Efflux Transporters Function. PLoS One (2016) 0.75
Altered intracellular pH regulation in cells with high levels of P-glycoprotein expression. Int J Biochem Mol Biol (2010) 0.75
The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells. BMC Genomics (2016) 0.75
Expression of KAP1 in epithelial ovarian cancer and its correlation with drug-resistance. Int J Clin Exp Med (2015) 0.75
Interactions of retinoids with the ABC transporters P-glycoprotein and Breast Cancer Resistance Protein. Sci Rep (2017) 0.75
The novel compound STK405759 is a microtubule-targeting agent with potent and selective cytotoxicity against multiple myeloma in vitro and in vivo. Oncotarget (2016) 0.75
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. Cell (2006) 8.61
Preferential origin and layer destination of GAD65-GFP cortical interneurons. Cereb Cortex (2004) 2.21
The zinc finger transcription factor Sp8 regulates the generation and diversity of olfactory bulb interneurons. Neuron (2006) 2.15
Parvalbumin-containing fast-spiking basket cells generate the field potential oscillations induced by cholinergic receptor activation in the hippocampus. J Neurosci (2010) 1.93
Electrical coupling among irregular-spiking GABAergic interneurons expressing cannabinoid receptors. J Neurosci (2004) 1.68
Stringent specificity in the construction of a GABAergic presynaptic inhibitory circuit. Cell (2009) 1.59
Effects of FP15, a peroxynitrite decomposition catalyst on cardiac and pulmonary function after cardiopulmonary bypass. Eur J Cardiothorac Surg (2012) 1.48
Biased selection of leading process branches mediates chemotaxis during tangential neuronal migration. Development (2009) 1.37
NMDA receptors increase the size of GABAergic terminals and enhance GABA release. J Neurosci (2005) 1.19
Comparative investigation of the left ventricular pressure-volume relationship in rat models of type 1 and type 2 diabetes mellitus. Am J Physiol Heart Circ Physiol (2009) 1.14
Pharmacological activation of soluble guanylate cyclase protects the heart against ischemic injury. Circulation (2009) 1.12
Cannabinoid sensitivity and synaptic properties of 2 GABAergic networks in the neocortex. Cereb Cortex (2008) 1.12
A single fear-inducing stimulus induces a transcription-dependent switch in synaptic AMPAR phenotype. Nat Neurosci (2009) 1.12
Development and evaluation of a perfusion decellularization porcine heart model--generation of 3-dimensional myocardial neoscaffolds. Circ J (2011) 1.10
miR-126 inhibits proliferation of small cell lung cancer cells by targeting SLC7A5. FEBS Lett (2011) 1.08
Glucose prevents the fall in ventromedial hypothalamic GABA that is required for full activation of glucose counterregulatory responses during hypoglycemia. Am J Physiol Endocrinol Metab (2010) 1.06
Visualization of stress-responsive inhibitory circuits in the GAD65-eGFP transgenic mice. Neurosci Lett (2005) 1.04
Class I HLA oligomerization at the surface of B cells is controlled by exogenous beta(2)-microglobulin: implications in activation of cytotoxic T lymphocytes. Int Immunol (2003) 1.01
Input-output features of anatomically identified CA3 neurons during hippocampal sharp wave/ripple oscillation in vitro. J Neurosci (2013) 1.00
Novel interneuronal network in the mouse posterior piriform cortex. J Comp Neurol (2006) 0.99
Lateral hypothalamic GAD65 neurons are spontaneously firing and distinct from orexin- and melanin-concentrating hormone neurons. J Physiol (2012) 0.99
The peroxynitrite decomposition catalyst FP15 improves ageing-associated cardiac and vascular dysfunction. Mech Ageing Dev (2006) 0.98
Raft and cytoskeleton associations of an ABC transporter: P-glycoprotein. Cytometry A (2004) 0.97
The small molecule Mek1/2 inhibitor U0126 disrupts the chordamesoderm to notochord transition in zebrafish. BMC Dev Biol (2008) 0.97
Physiological sharp wave-ripples and interictal events in vitro: what's the difference? Brain (2014) 0.96
Pre-conditioning with the soluble guanylate cyclase activator Cinaciguat reduces ischaemia-reperfusion injury after cardiopulmonary bypass. Eur J Cardiothorac Surg (2010) 0.96
Improvement of infrared single-photon detectors absorptance by integrated plasmonic structures. Sci Rep (2013) 0.94
Endocannabinoid-mediated long-term depression of afferent excitatory synapses in hippocampal pyramidal cells and GABAergic interneurons. J Neurosci (2012) 0.92
In vivo and in vitro multitracer analyses of P-glycoprotein expression-related multidrug resistance. Eur J Nucl Med Mol Imaging (2003) 0.92
GABA(A) and GABA(B) receptors of distinct properties affect oppositely the proliferation of mouse embryonic stem cells through synergistic elevation of intracellular Ca(2+). FASEB J (2009) 0.91
Autonomous vascular networks synchronize GABA neuron migration in the embryonic forebrain. Nat Commun (2013) 0.91
Selective phosphodiesterase-5 (PDE-5) inhibitor vardenafil ameliorates renal damage in type 1 diabetic rats by restoring cyclic 3',5' guanosine monophosphate (cGMP) level in podocytes. Nephrol Dial Transplant (2012) 0.91
Concepts for visualization of multidirectional phase-contrast MRI of the heart and large thoracic vessels. Acad Radiol (2008) 0.91
Activation of the peroxynitrite-poly(adenosine diphosphate-ribose) polymerase pathway during neointima proliferation: a new target to prevent restenosis after endarterectomy. J Vasc Surg (2006) 0.90
Reendothelialization of human heart valve neoscaffolds using umbilical cord-derived endothelial cells. Circ J (2012) 0.90
Tricuspid valve endocarditis with septic pulmonary emboli in a drug addict. Ann Thorac Cardiovasc Surg (2012) 0.89
Spatiotemporal expression pattern of DsRedT3/CCK gene construct during postnatal development of myenteric plexus in transgenic mice. Cell Tissue Res (2013) 0.89
Single dose treatment with PARP-inhibitor INO-1001 improves aging-associated cardiac and vascular dysfunction. Exp Gerontol (2007) 0.89
Properties of a population of GABAergic cells in murine auditory cortex weakly excited by thalamic stimulation. J Neurophysiol (2006) 0.88
Complete inhibition of P-glycoprotein by simultaneous treatment with a distinct class of modulators and the UIC2 monoclonal antibody. J Pharmacol Exp Ther (2006) 0.88
Rat model of exercise-induced cardiac hypertrophy: hemodynamic characterization using left ventricular pressure-volume analysis. Am J Physiol Heart Circ Physiol (2013) 0.87
Poly(ADP-ribose) polymerase inhibition improves endothelial dysfunction induced by reactive oxidant hydrogen peroxide in vitro. Eur J Pharmacol (2007) 0.87
Differential metabotropic glutamate receptor expression and modulation in two neocortical inhibitory networks. J Neurophysiol (2009) 0.87
Ribonucleoprotein-masked nicks at 50-kbp intervals in the eukaryotic genomic DNA. Proc Natl Acad Sci U S A (2007) 0.87
Mesenteric complications after hypothermic cardiopulmonary bypass with cardiac arrest: underlying mechanisms. Artif Organs (2002) 0.86
Mammalian retinal horizontal cells are unconventional GABAergic neurons. J Neurochem (2010) 0.86
The neurochemically diverse intermedius nucleus of the medulla as a source of excitatory and inhibitory synaptic input to the nucleus tractus solitarii. J Neurosci (2007) 0.86
Homo- and heteroexchange of adenine nucleotides and nucleosides in rat hippocampal slices by the nucleoside transport system. Br J Pharmacol (2003) 0.85
Oxidative stress and regional ischemia-reperfusion injury: the peroxynitrite-poly(ADP-ribose) polymerase connection. Coron Artery Dis (2003) 0.85
Endothelial dysfunction after long-term cold storage in HTK organ preservation solutions: effects of iron chelators and N-alpha-acetyl-L-histidine. J Heart Lung Transplant (2008) 0.85
Incidence of neurological complications following overstenting of the left subclavian artery. Eur J Cardiothorac Surg (2007) 0.85
Effects of selective phosphodiesterase-5-inhibition on myocardial contractility and reperfusion injury after heart transplantation. Transplantation (2008) 0.85
Anatomically heterogeneous populations of CB1 cannabinoid receptor-expressing interneurons in the CA3 region of the hippocampus show homogeneous input-output characteristics. Hippocampus (2014) 0.85
High throughput FRET analysis of protein-protein interactions by slide-based imaging laser scanning cytometry. Cytometry A (2013) 0.84
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies. Biochem Biophys Res Commun (2004) 0.84
P-glycoprotein inhibition by membrane cholesterol modulation. Eur J Pharm Sci (2008) 0.84
Pgp inhibition by UIC2 antibody can be followed in vitro by using tumor-diagnostic radiotracers, 99mTc-MIBI and 18FDG. Eur J Pharm Sci (2010) 0.84
Endothelial dysfunction after hypoxia-reoxygenation: do in vitro models work? Vascul Pharmacol (2009) 0.83
P2X receptor activation elicits transporter-mediated noradrenaline release from rat hippocampal slices. J Pharmacol Exp Ther (2004) 0.83
Biphasic accumulation kinetics of [99mTc]-hexakis-2-methoxyisobutyl isonitrile in tumour cells and its modulation by lipophilic P-glycoprotein ligands. Eur J Pharm Sci (2005) 0.82
Cholesterol sensitivity of detergent resistance: a rapid flow cytometric test for detecting constitutive or induced raft association of membrane proteins. Cytometry A (2004) 0.82
Myocardial protection after systemic application of L-arginine during reperfusion. J Cardiovasc Pharmacol (2004) 0.82
Separation of 1-23-kb complementary DNA strands by urea-agarose gel electrophoresis. Nucleic Acids Res (2009) 0.82
Methane biogenesis during sodium azide-induced chemical hypoxia in rats. Am J Physiol Cell Physiol (2012) 0.81
PRMT1 and PRMT8 regulate retinoic acid-dependent neuronal differentiation with implications to neuropathology. Stem Cells (2015) 0.81
Vascular dysfunction induced by hypochlorite is improved by the selective phosphodiesterase-5-inhibitor vardenafil. Eur J Pharmacol (2013) 0.81
Acute ethanol exposure increases the susceptibility of the donor hearts to ischemia/reperfusion injury after transplantation in rats. PLoS One (2012) 0.81
Effects of ATP depletion and phosphate analogues on P-glycoprotein conformation in live cells. Eur J Biochem (2002) 0.81
Human serum amyloid P component attenuates the bacterial lipopolysaccharide-induced increase in blood-brain barrier permeability in mice. Neurosci Lett (2003) 0.81
GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality. Dev Dyn (2008) 0.81
In vitro generation of atrioventricular heart valve neoscaffolds. Artif Organs (2014) 0.81
Entanglement of a circular mapping catheter in the mitral valve with persistent iatrogenic atrial septal defect after attempted pulmonary vein isolation: a word of caution. Ann Thorac Cardiovasc Surg (2012) 0.81
Sequential induction of embryonic and adult forms of glutamic acid decarboxylase during in vitro-induced neurogenesis in cloned neuroectodermal cell-line, NE-7C2. J Neurochem (2002) 0.80
Mesenteric vascular dysfunction after cardiopulmonary bypass with cardiac arrest is aggravated by coexistent heart failure. Shock (2005) 0.80
Early maternal separation, nightmares, and bad dreams: results from the Hungarostudy Epidemiological Panel. Attach Hum Dev (2011) 0.80
Isoenzyme-specific regulation of cardiac Kv1.5/Kvβ1.2 ion channel complex by protein kinase C: central role of PKCβII. Naunyn Schmiedebergs Arch Pharmacol (2014) 0.80
Membrane topography of HLA I, HLA II, and ICAM-1 is affected by IFN-gamma in lipid rafts of uveal melanomas. Biochem Biophys Res Commun (2004) 0.80
Dose-dependent effects of a selective phosphodiesterase-5-inhibitor on endothelial dysfunction induced by peroxynitrite in rat aorta. Eur J Pharmacol (2009) 0.80
Nick-forming sequences may be involved in the organization of eukaryotic chromatin into approximately 50 kbp loops. Histochem Cell Biol (2005) 0.80
Development of a stereological method to measure levels of fluoropyrimidine metabolizing enzymes in tumor sections using laser scanning cytometry. Cytometry A (2005) 0.80
Nitric oxide- and heme-independent activation of soluble guanylate cyclase attenuates peroxynitrite-induced endothelial dysfunction in rat aorta. J Cardiovasc Pharmacol Ther (2012) 0.80
Provocation of an autoimmune response to cardiac voltage-gated sodium channel NaV1.5 induces cardiac conduction defects in rats. J Am Coll Cardiol (2013) 0.80
GABAergic signaling in primary lens epithelial and lentoid cells and its involvement in intracellular Ca2+ modulation. Cell Calcium (2011) 0.79
Improvement of aging-associated cardiovascular dysfunction by the orally administered copper(II)-aspirinate complex. Rejuvenation Res (2008) 0.79
Enhanced dendritic action potential backpropagation in parvalbumin-positive basket cells during sharp wave activity. Neurochem Res (2010) 0.79
Biological microbeads for flow-cytometric immunoassays, enzyme titrations, and quantitative PCR. Cytometry A (2005) 0.79
Identification of the adrenoceptor subtypes expressed on GABAergic neurons in the anterior hypothalamic area and rostral zona incerta of GAD65-eGFP transgenic mice. Neurosci Lett (2007) 0.79
Treatment of arrhythmias by external charged particle beams: a Langendorff feasibility study. Biomed Tech (Berl) (2015) 0.78
Follow-up analysis of pregnancies complicated by HELLP syndrome. Fetal Diagn Ther (2006) 0.78
GAD isoforms exhibit distinct spatiotemporal expression patterns in the developing mouse lens: correlation with Dlx2 and Dlx5. Dev Dyn (2007) 0.78
Effects of Custodiol-N, a novel organ preservation solution, on ischemia/reperfusion injury. J Thorac Cardiovasc Surg (2009) 0.78
Effects of inosine on reperfusion injury after cardiopulmonary bypass. J Cardiothorac Surg (2010) 0.78