PubRank

Lawrence Colwell

Author PubWeight™ 14.08‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Platensimycin is a selective FabF inhibitor with potent antibiotic properties. Nature 2006 5.81
2 Benzoyl 2-methyl indoles as selective PPARgamma modulators. Bioorg Med Chem Lett 2005 1.17
3 Selective PPARgamma modulators with improved pharmacological profiles. Bioorg Med Chem Lett 2005 0.85
4 Discovery of (2R)-2-(3-{3-[(4-Methoxyphenyl)carbonyl]-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl}phenoxy)butanoic acid (MK-0533): a novel selective peroxisome proliferator-activated receptor gamma modulator for the treatment of type 2 diabetes mellitus with a reduced potential to increase plasma and extracellular fluid volume. J Med Chem 2009 0.83
5 Design, synthesis, and structure-activity relationship of podocarpic acid amides as liver X receptor agonists for potential treatment of atherosclerosis. Bioorg Med Chem Lett 2005 0.80
6 Estrogen receptor ligands. Part 10: Chromanes: old scaffolds for new SERAMs. Bioorg Med Chem Lett 2005 0.79
7 Thiophenyl oxime-derived phosphonates as nano-molar class C beta-lactamase inhibitors reducing MIC of imipenem against Pseudomonas aeruginosa and Acinetobacter baumannii. Bioorg Med Chem Lett 2011 0.79
8 Nocathiacin analogs: Synthesis and antibacterial activity of novel water-soluble amides. Bioorg Med Chem Lett 2009 0.79
9 Comparison of the effects of perfusion in determining brain penetration (brain-to-plasma ratios) of small molecules in rats. Comp Med 2004 0.77
10 Highly functionalized 7-azaindoles as selective PPAR gamma modulators. Bioorg Med Chem Lett 2008 0.76
11 Estrogen receptor ligands. Part 4: The SAR of the syn-dihydrobenzoxathiin SERAMs. Bioorg Med Chem Lett 2004 0.75
12 Evaluation of endo- and exo-aryl-substitutions and central scaffold modifications on diphenyl substituted alkanes as 5-lipoxygenase activating protein inhibitors. Bioorg Med Chem Lett 2012 0.75