Physico-chemical characterisation of PLGA nanoparticles after freeze-drying and storage.

PubWeight™: 1.10‹?› | Rank: Top 10%

🔗 View Article (PMID 19462479)

Published in Eur J Pharm Biopharm on June 01, 2009

Authors

Melisande Holzer1, Vitali Vogel, Werner Mäntele, Daniel Schwartz, Winfried Haase, Klaus Langer

Author Affiliations

1: Institut für Pharmazeutische Technologie, Goethe-Universität, Frankfurt am Main, Germany.

Articles citing this

Reconstitutable charged polymeric (PLGA)(2)-b-PEI micelles for gene therapeutics delivery. Biomaterials (2011) 0.95

Antitumoral activity of L-ascorbic acid-poly- D,L-(lactide-co-glycolide) nanoparticles containing violacein. Int J Nanomedicine (2010) 0.94

Scale up, optimization and stability analysis of Curcumin C3 complex-loaded nanoparticles for cancer therapy. J Nanobiotechnology (2012) 0.91

Practical preparation procedures for docetaxel-loaded nanoparticles using polylactic acid-co-glycolic acid. Int J Nanomedicine (2011) 0.88

Application of nanotechnologies for improved immune response against infectious diseases in the developing world. Adv Drug Deliv Rev (2009) 0.84

Effect of cryoprotectants on the porosity and stability of insulin-loaded PLGA nanoparticles after freeze-drying. Biomatter (2013) 0.82

Cryoprotection-lyophilization and physical stabilization of rifampicin-loaded flower-like polymeric micelles. J R Soc Interface (2011) 0.78

Formulation of diblock polymeric nanoparticles through nanoprecipitation technique. J Vis Exp (2011) 0.77

PLGA nanoparticles as a platform for vitamin D-based cancer therapy. Beilstein J Nanotechnol (2015) 0.77

Development and characterization of lyophilized diazepam-loaded polymeric micelles. AAPS PharmSciTech (2013) 0.76

Poly(lactic-co-glycolic) Acid-Chitosan Dual Loaded Nanoparticles for Antiretroviral Nanoformulations. J Drug Deliv (2016) 0.75

Online monitoring of PLGA microparticles formation using Lasentec focused beam reflectance (FBRM) and particle video microscope (PVM). AAPS J (2010) 0.75

Synthesis and characterization of a poly(lactic-co-glycolic acid) core + poly(N-isopropylacrylamide) shell nanoparticle system. Biomatter (2013) 0.75

Articles by these authors

Large-scale characterization of HeLa cell nuclear phosphoproteins. Proc Natl Acad Sci U S A (2004) 10.78

A proteomics approach to understanding protein ubiquitination. Nat Biotechnol (2003) 10.51

Phosphoproteomic analysis of the developing mouse brain. Mol Cell Proteomics (2004) 2.50

CHIP-Hsc70 complex ubiquitinates phosphorylated tau and enhances cell survival. J Biol Chem (2003) 2.27

Three-dimensional structure of the bacterial protein-translocation complex SecYEG. Nature (2002) 2.16

Extensive phosphorylation with overlapping specificity by Mycobacterium tuberculosis serine/threonine protein kinases. Proc Natl Acad Sci U S A (2010) 1.67

The membrane protein FeoB contains an intramolecular G protein essential for Fe(II) uptake in bacteria. Proc Natl Acad Sci U S A (2002) 1.66

Biological sequence motif discovery using motif-x. Curr Protoc Bioinformatics (2011) 1.60

pLogo: a probabilistic approach to visualizing sequence motifs. Nat Methods (2013) 1.55

Risk of recurrent stroke in children with sickle cell disease receiving blood transfusion therapy for at least five years after initial stroke. J Pediatr (2002) 1.50

Delay discounting behavior and white matter microstructure abnormalities in youth with a family history of alcoholism. Alcohol Clin Exp Res (2010) 1.49

Correction of residual hyperopia after cataract surgery using the light adjustable intraocular lens technology. Am J Ophthalmol (2008) 1.48

High level cell-free expression and specific labeling of integral membrane proteins. Eur J Biochem (2004) 1.45

Evaluation of detergents for the soluble expression of alpha-helical and beta-barrel-type integral membrane proteins by a preparative scale individual cell-free expression system. FEBS J (2005) 1.44

DYX1C1 is required for axonemal dynein assembly and ciliary motility. Nat Genet (2013) 1.44

Comparison of scanning electron microscopy, dynamic light scattering and analytical ultracentrifugation for the sizing of poly(butyl cyanoacrylate) nanoparticles. Eur J Pharm Biopharm (2004) 1.41

Structural evolution of C-terminal domains in the p53 family. EMBO J (2007) 1.32

Large-scale phosphoprotein analysis in Medicago truncatula roots provides insight into in vivo kinase activity in legumes. Plant Physiol (2009) 1.27

Cell-free production of G protein-coupled receptors for functional and structural studies. J Struct Biol (2007) 1.24

Trastuzumab-modified nanoparticles: optimisation of preparation and uptake in cancer cells. Biomaterials (2006) 1.20

Human serum albumin-polyethylenimine nanoparticles for gene delivery. J Control Release (2003) 1.20

Structural and functional fingerprint of the mitochondrial ATP-binding cassette transporter Mdl1 from Saccharomyces cerevisiae. J Biol Chem (2006) 1.18

Covalent attachment of apolipoprotein A-I and apolipoprotein B-100 to albumin nanoparticles enables drug transport into the brain. J Control Release (2006) 1.18

N-acetyl-L-cysteine (NAC) inhibits virus replication and expression of pro-inflammatory molecules in A549 cells infected with highly pathogenic H5N1 influenza A virus. Biochem Pharmacol (2009) 1.16

Identification of 14-3-3epsilon substrates from embryonic murine brain. J Proteome Res (2006) 1.15

Supramolecular photosystem II organization in grana thylakoid membranes: evidence for a structured arrangement. Biochemistry (2004) 1.14

Multimodality monitoring of transcranial electric motor and somatosensory-evoked potentials during surgical correction of spinal deformity in patients with cerebral palsy and other neuromuscular disorders. Spine (Phila Pa 1976) (2003) 1.13

Selective targeting of antibody-conjugated nanoparticles to leukemic cells and primary T-lymphocytes. Biomaterials (2005) 1.10

The bacterial protein-translocation complex: SecYEG dimers associate with one or two SecA molecules. J Mol Biol (2004) 1.09

Specific targeting of HER2 overexpressing breast cancer cells with doxorubicin-loaded trastuzumab-modified human serum albumin nanoparticles. Bioconjug Chem (2008) 1.08

Highly specific HER2-mediated cellular uptake of antibody-modified nanoparticles in tumour cells. J Drug Target (2004) 1.08

Endogenous production of reactive oxygen species is required for stimulation of human articular chondrocyte matrix metalloproteinase production by fibronectin fragments. Free Radic Biol Med (2007) 1.04

Low-light-induced formation of semicrystalline photosystem II arrays in higher plant chloroplasts. Biochemistry (2007) 1.03

Needle thoracostomy for tension pneumothorax: failure predicted by chest computed tomography. Prehosp Emerg Care (2009) 1.02

Projection structure of yidC: a conserved mediator of membrane protein assembly. J Mol Biol (2007) 1.00

A new link to mitochondrial impairment in tauopathies. Mol Neurobiol (2012) 1.00

Efficient light harvesting by photosystem II requires an optimized protein packing density in Grana thylakoids. J Biol Chem (2010) 1.00

Preparatory activity in occipital cortex in early blind humans predicts auditory perceptual performance. J Neurosci (2007) 0.99

Preparation and characterisation of antibody modified gelatin nanoparticles as drug carrier system for uptake in lymphocytes. Biomaterials (2005) 0.99

Windowless ultrasound photoacoustic cell for in vivo mid-IR spectroscopy of human epidermis: low interference by changes of air pressure, temperature, and humidity caused by skin contact opens the possibility for a non-invasive monitoring of glucose in the interstitial fluid. Rev Sci Instrum (2013) 0.98

Freeze drying of human serum albumin (HSA) nanoparticles with different excipients. Int J Pharm (2008) 0.98

In vivo noninvasive monitoring of glucose concentration in human epidermis by mid-infrared pulsed photoacoustic spectroscopy. Anal Chem (2012) 0.98

The key residue for substrate transport (Glu14) in the EmrE dimer is asymmetric. J Biol Chem (2007) 0.97

Orienting auditory spatial attention engages frontal eye fields and medial occipital cortex in congenitally blind humans. Neuropsychologia (2007) 0.96

Targeted human serum albumin nanoparticles for specific uptake in EGFR-Expressing colon carcinoma cells. Nanomedicine (2011) 0.96

Respiratory chain complexes in dynamic mitochondria display a patchy distribution in life cells. PLoS One (2010) 0.96

Heterologous production in Wolinella succinogenes and characterization of the quinol:fumarate reductase enzymes from Helicobacter pylori and Campylobacter jejuni. Biochem J (2006) 0.95

Ultraconserved elements: analyses of dosage sensitivity, motifs and boundaries. Genetics (2008) 0.95

Structural and functional self-organization of Photosystem II in grana thylakoids. Biochim Biophys Acta (2007) 0.94

Heterologous expression and comparative characterization of the human neuromedin U subtype II receptor using the methylotrophic yeast Pichia pastoris and mammalian cells. Int J Biochem Cell Biol (2007) 0.94

Aquaglyceroporins, one channel for two molecules. Biochim Biophys Acta (2002) 0.93

Infrared spectroscopic analysis of human interstitial fluid in vitro and in vivo using FT-IR spectroscopy and pulsed quantum cascade lasers (QCL): Establishing a new approach to non invasive glucose measurement. Spectrochim Acta A Mol Biomol Spectrosc (2011) 0.93

Discounting of delayed rewards and executive dysfunction in individuals infected with hepatitis C. J Clin Exp Neuropsychol (2010) 0.93

Cisplatin-resistant neuroblastoma cells express enhanced levels of epidermal growth factor receptor (EGFR) and are sensitive to treatment with EGFR-specific toxins. Clin Cancer Res (2008) 0.93

The role of single subunits of the DNA transport machinery of Thermus thermophilus HB27 in DNA binding and transport. Environ Microbiol (2009) 0.92

Human leukotriene C(4) synthase at 4.5 A resolution in projection. Structure (2004) 0.91

Tumour cell delivery of antisense oligonuclceotides by human serum albumin nanoparticles. J Control Release (2004) 0.90

Enhanced drug targeting by attachment of an anti alphav integrin antibody to doxorubicin loaded human serum albumin nanoparticles. Biomaterials (2009) 0.90

Thermal stability of trimeric light-harvesting chlorophyll a/b complex (LHCIIb) in liposomes of thylakoid lipids. Biochim Biophys Acta (2006) 0.90

Effect of trastuzumab-modified antisense oligonucleotide-loaded human serum albumin nanoparticles prepared by heat denaturation. Biomaterials (2008) 0.90

Novel photosensitizer-protein nanoparticles for photodynamic therapy: photophysical characterization and in vitro investigations. J Photochem Photobiol B (2009) 0.90

Use of intravenous lipid emulsion to reverse central nervous system toxicity of an iatrogenic local anesthetic overdose in a patient on peritoneal dialysis. Ann Pharmacother (2012) 0.89

Dimer-tetramer transition controls RUNX1/ETO leukemogenic activity. Blood (2010) 0.89

The clinical and genomic significance of donor-specific antibody-positive/C4d-negative and donor-specific antibody-negative/C4d-negative transplant glomerulopathy. Clin J Am Soc Nephrol (2013) 0.89

Epithelial-myoepithelial carcinoma of the lung: a case report and review of the literature. J Pediatr Hematol Oncol (2009) 0.89

Two-dimensional crystallization of human vitamin K-dependent gamma-glutamyl carboxylase. J Struct Biol (2006) 0.89

Perceived barriers to guidelines in peritoneal dialysis. Nephrol Dial Transplant (2010) 0.88

Using bacteria to determine protein kinase specificity and predict target substrates. PLoS One (2012) 0.88

Clinical chemistry without reagents? An infrared spectroscopic technique for determination of clinically relevant constituents of body fluids. Anal Bioanal Chem (2006) 0.88

Redox-triggered FTIR difference spectra of FAD in aqueous solution and bound to flavoproteins. Biochemistry (2003) 0.88

Employing Rhodobacter sphaeroides to functionally express and purify human G protein-coupled receptors. Biol Chem (2008) 0.88

Oligonucleotide-protamine-albumin nanoparticles: preparation, physical properties, and intracellular distribution. J Control Release (2005) 0.87

Downregulation of Plk1 expression by receptor-mediated uptake of antisense oligonucleotide-loaded nanoparticles. Neoplasia (2008) 0.87

High-yield expression, reconstitution and structure of the recombinant, fully functional glutamate transporter GLT-1 from Rattus norvegicus. J Mol Biol (2005) 0.87

Vibrational modes of tyrosines in cytochrome c oxidase from Paracoccus denitrificans: FTIR and electrochemical studies on Tyr-D4-labeled and on Tyr280His and Tyr35Phe mutant enzymes. Biochemistry (2002) 0.87

Arthroscopic posterior bone block: surgical technique. Musculoskelet Surg (2012) 0.87

Probing heme propionate involvement in transmembrane proton transfer coupled to electron transfer in dihemic quinol:fumarate reductase by 13C-labeling and FTIR difference spectroscopy. Biochemistry (2005) 0.86

Characterisation of YtfM, a second member of the Omp85 family in Escherichia coli. Biol Chem (2007) 0.86

Experimental support for the "E pathway hypothesis" of coupled transmembrane e- and H+ transfer in dihemic quinol:fumarate reductase. Proc Natl Acad Sci U S A (2005) 0.86

Oligonucleotide-protamine-albumin nanoparticles: Protamine sulfate causes drastic size reduction. J Control Release (2005) 0.85

Transphosphorylation of E. coli Proteins during Production of Recombinant Protein Kinases Provides a Robust System to Characterize Kinase Specificity. Front Plant Sci (2012) 0.85

MicroRNA-9 and microRNA-326 regulate human dopamine D2 receptor expression, and the microRNA-mediated expression regulation is altered by a genetic variant. J Biol Chem (2014) 0.85

Do e-mail alerts of new research increase knowledge translation? A "Nephrology Now" randomized control trial. Acad Med (2011) 0.85

Temperature imaging of laser-induced thermotherapy (LITT) by MRI: evaluation of different sequences in phantom. Lasers Med Sci (2013) 0.84

Proteorhodopsin: characterisation of 2D crystals by electron microscopy and solid state NMR. Biochim Biophys Acta (2007) 0.84

Peptide specificity and lipid activation of the lysosomal transport complex ABCB9 (TAPL). J Biol Chem (2008) 0.84

Evaluation of deficiencies in current discharge summaries for dialysis patients in Canada. J Multidiscip Healthc (2012) 0.84

Knowledge translation for nephrologists: strategies for improving the identification of patients with proteinuria. J Nephrol (2012) 0.84

A liver-mimicking MRI phantom for thermal ablation experiments. Med Phys (2011) 0.83

Characterizing a monotopic membrane enzyme. Biochemical, enzymatic and crystallization studies on Aquifex aeolicus sulfide:quinone oxidoreductase. Biochim Biophys Acta (2010) 0.83

FTIR difference spectra of Wolinella succinogenes quinol:fumarate reductase support a key role of Glu C180 within the "E-pathway hypothesis" of coupled transmembrane electron and proton transfer. Biochemistry (2005) 0.83

Archaea in the Gulf of Aqaba. FEMS Microbiol Ecol (2009) 0.83

The role of Val-265 for flavin adenine dinucleotide (FAD) binding in pyruvate oxidase: FTIR, kinetic, and crystallographic studies on the enzyme variant V265A. Biochemistry (2005) 0.83

Production of the human D2S receptor in the methylotrophic yeast P. pastoris. Receptors Channels (2004) 0.83