Influence of polyethylene glycol/polyethylene oxide on the release characteristics of sustained-release ethylcellulose mini-matrices produced by hot-melt extrusion: in vitro and in vivo evaluations.

PubWeight™: 0.91‹?›

🔗 View Article (PMID 19462482)

Published in Eur J Pharm Biopharm on June 01, 2009

Authors

E Verhoeven1, T R M De Beer, E Schacht, G Van den Mooter, J P Remon, C Vervaet

Author Affiliations

1: Laboratory of Pharmaceutical Technology, Ghent University, Ghent, Belgium.

Articles by these authors

Development and testing of bioadhesive, fluoride-containing slow-release tablets for oral use. J Pharm Pharmacol (1991) 2.25

Effectiveness of pharmacist intervention for asthma control improvement. Eur Respir J (2007) 2.13

Superiority of alfacalcidol over plain vitamin D in the treatment of glucocorticoid-induced osteoporosis. Rheumatol Int (2003) 2.07

The quality of essential antimicrobial and antimalarial drugs marketed in Rwanda and Tanzania: influence of tropical storage conditions on in vitro dissolution. J Clin Pharm Ther (2004) 1.71

Production of pellets via extrusion-spheronisation without the incorporation of microcrystalline cellulose: a critical review. Eur J Pharm Biopharm (2008) 1.70

Biopolymer-based hydrogels as scaffolds for tissue engineering applications: a review. Biomacromolecules (2011) 1.68

Kinetics of Pseudomonas aeruginosa adhesion to 304 and 316-L stainless steel: role of cell surface hydrophobicity. Appl Environ Microbiol (1990) 1.57

The dissolution rate and bioavailability of hydrochlorothiazide in pellet formulations. J Pharm Pharmacol (1988) 1.39

In-line and real-time process monitoring of a freeze drying process using Raman and NIR spectroscopy as complementary process analytical technology (PAT) tools. J Pharm Sci (2009) 1.29

Antiretroviral efficacy and pharmacokinetics of oral bis(isopropyloxycarbonyloxymethyl)-9-(2-phosphonylmethoxypropyl)adenine in mice. Antimicrob Agents Chemother (1998) 1.26

Physicochemical characterization of solid dispersions of the antiviral agent UC-781 with polyethylene glycol 6000 and Gelucire 44/14. Eur J Pharm Sci (2000) 1.21

Comparison of salivary miconazole concentrations after administration of a bioadhesive slow-release buccal tablet and an oral gel. Eur J Clin Pharmacol (1992) 1.11

Near infrared and Raman spectroscopy for the in-process monitoring of pharmaceutical production processes. Int J Pharm (2010) 1.09

Mechanism of increased dissolution of diazepam and temazepam from polyethylene glycol 6000 solid dispersions. Int J Pharm (2002) 1.07

Vitamin D analogs versus native vitamin D in preventing bone loss and osteoporosis-related fractures: a comparative meta-analysis. Calcif Tissue Int (2005) 1.01

Use of block copolymers of poly(ortho esters) and poly (ethylene glycol) micellar carriers as potential tumour targeting systems. J Drug Target (2003) 1.00

Characteristics of interpolyelectrolyte complexes of Eudragit E100 with Eudragit L100. J Control Release (2005) 0.99

Local methylprednisolone inhibition of foreign body response to coated intracoronary stents. Coron Artery Dis (1996) 0.98

Wax beads as cushioning agents during the compression of coated diltiazem pellets. Eur J Pharm Sci (2002) 0.98

Characterization of physico-chemical properties and pharmaceutical performance of sucrose co-freeze-dried solid nanoparticulate powders of the anti-HIV agent loviride prepared by media milling. Int J Pharm (2007) 0.98

Superiority of a combined treatment of Alendronate and Alfacalcidol compared to the combination of Alendronate and plain vitamin D or Alfacalcidol alone in established postmenopausal or male osteoporosis (AAC-Trial). Rheumatol Int (2007) 0.97

Drug formulations intended for the global market should be tested for stability under tropical climatic conditions. Eur J Clin Pharmacol (2003) 0.97

Physical stability of solid dispersions of the antiviral agent UC-781 with PEG 6000, Gelucire 44/14 and PVP K30. Int J Pharm (2002) 0.96

Comparison of salivary fluoride concentrations after administration of a bioadhesive slow-release tablet and a conventional fluoride tablet. J Pharm Pharmacol (1992) 0.96

Trypsin inhibition, calcium and zinc ion binding of starch-g-poly(acrylic acid) copolymers and starch/poly(acrylic acid) mixtures for peroral peptide drug delivery. J Control Release (2001) 0.95

PLGA nanoparticles and nanosuspensions with amphotericin B: Potent in vitro and in vivo alternatives to Fungizone and AmBisome. J Control Release (2012) 0.94

Simulated intestinal fluid as transport medium in the Caco-2 cell culture model. Int J Pharm (2002) 0.94

Optimization and validation of a micellar electrokinetic chromatographic method for the analysis of several angiotensin-II-receptor antagonists. J Chromatogr A (2003) 0.93

Influence of chopper and mixer speeds and microwave power level during the high-shear granulation process on the final granule characteristics. Drug Dev Ind Pharm (1999) 0.93

[Proximal femoral fractures in the elderly: pathogenesis, sequelae, interventions]. Rehabilitation (Stuttg) (1999) 0.93

Evaluation of a mucoadhesive tablet for ocular use. J Control Release (2001) 0.93

Characterization of protein-resistant dextran monolayers. Biomaterials (2000) 0.93

In vitro release characteristics of bioactive molecules from dextran dialdehyde cross-linked gelatin hydrogel films. Biomaterials (1998) 0.93

In-vitro bioadhesion of a buccal, miconazole slow-release tablet. J Pharm Pharmacol (1993) 0.92

Raman spectroscopy for the in-line polymer-drug quantification and solid state characterization during a pharmaceutical hot-melt extrusion process. Eur J Pharm Biopharm (2010) 0.92

Polymeric prodrugs. Int J Pharm (2004) 0.91

In vitro and in vivo biocompatibility of dextran dialdehyde cross-linked gelatin hydrogel films. Biomaterials (1998) 0.91

Preparation and characterisation of rose Bengal-loaded surface-modified albumin nanoparticles. J Control Release (2001) 0.91

Gastrointestinal transit time of nondisintegrating radio-opaque pellets in suckling and recently weaned piglets. J Control Release (2004) 0.90

Quantitative determination of p-aminosalicylic acid and its degradation product m-aminophenol in pellets by ion-pair high-performance liquid chromatography applying the monolithic Chromolith Speedrod RP-18e column. Biomed Chromatogr (2004) 0.90

Endotoxin removal by end-line filters. J Clin Microbiol (1989) 0.90

Raman spectroscopy as a process analytical technology tool for the understanding and the quantitative in-line monitoring of the homogenization process of a pharmaceutical suspension. Analyst (2006) 0.90

Development of directly compressible powders via co-spray drying. Eur J Pharm Biopharm (2007) 0.90

Xanthan gum to tailor drug release of sustained-release ethylcellulose mini-matrices prepared via hot-melt extrusion: in vitro and in vivo evaluation. Eur J Pharm Biopharm (2006) 0.90

An improved extraction procedure for the liquid chromatographic determination of propranolol and 4-hydroxypropranolol in plasma. Br J Clin Pharmacol (1980) 0.90

Biocompatibility of polymer-coated oversized metallic stents implanted in normal porcine coronary arteries. Atherosclerosis (1995) 0.90

An oral controlled release matrix pellet formulation containing nanocrystalline ketoprofen. Int J Pharm (2001) 0.89

Medication use and disease control of asthmatic patients in Flanders: a cross-sectional community pharmacy study. Respir Med (2006) 0.89

Quinine sulphate pellets for flexible pediatric drug dosing: formulation development and evaluation of taste-masking efficiency using the electronic tongue. Eur J Pharm Biopharm (2006) 0.89

Chemoprophylaxis of fungal deterioration of the Provox silicone tracheoesophageal prosthesis in postlaryngectomy patients. Ann Otol Rhinol Laryngol (1997) 0.89

Deterioration of the Provox silicone tracheoesophageal voice prosthesis: microbial aspects and structural changes. Acta Otolaryngol (1997) 0.89

Multifactorial pathogenesis of falls as a basis for multifactorial interventions. J Musculoskelet Neuronal Interact (2005) 0.88

Better functional mobility in community-dwelling elderly is related to D-hormone serum levels and to daily calcium intake. J Nutr Health Aging (2005) 0.88

Enhancing bone healing and regeneration: present and future perspectives in veterinary orthopaedics. Vet Comp Orthop Traumatol (2010) 0.88

Evaluation of the potential of ion pair formation to improve the oral absorption of two potent antiviral compounds, AMD3100 and PMPA. Int J Pharm (1999) 0.88

In vitro cytotoxicity of paclitaxel/beta-cyclodextrin complexes for HIPEC. Int J Pharm (2008) 0.88

Species-dependent and site-specific intestinal metabolism of ester prodrugs. Int J Pharm (2000) 0.87

Preparation of sterically stabilized human serum albumin nanospheres using a novel Dextranox-MPEG crosslinking agent. Pharm Res (1994) 0.87

Raman spectroscopic method for the determination of medroxyprogesterone acetate in a pharmaceutical suspension: validation of quantifying abilities, uncertainty assessment and comparison with the high performance liquid chromatography reference method. Anal Chim Acta (2007) 0.87

In vitro activities of doxycycline and enrofloxacin against European Chlamydia psittaci strains from turkeys. Antimicrob Agents Chemother (1997) 0.87

Spray-dried Amioca starch/Carbopol 974P mixtures as buccal bioadhesive carriers. Int J Pharm (2005) 0.87

Deposition of differently sized airborne microspheres in the respiratory tract of chickens. Avian Pathol (2006) 0.86

Dissolution enhancement of the anti-HIV drug UC 781 by formulation in a ternary solid dispersion with TPGS 1000 and Eudragit E100. Eur J Pharm Biopharm (2008) 0.86

Characterization and in vivo evaluation of ocular minitablets prepared with different bioadhesive Carbopol-starch components. Eur J Pharm Biopharm (2005) 0.86

Design and fabrication of a low cost implantable bladder pressure monitor. Conf Proc IEEE Eng Med Biol Soc (2009) 0.86

Characterization and evaluation of isomalt performance in direct compression. Int J Pharm (1999) 0.86

Influence of formulation and process parameters on the release characteristics of ethylcellulose sustained-release mini-matrices produced by hot-melt extrusion. Eur J Pharm Biopharm (2007) 0.86

Treatment of glucocorticoid-induced osteoporosis with alfacalcidol/calcium versus vitamin D/calcium. Calcif Tissue Int (1999) 0.85

Direct compression and moulding properties of co-extruded isomalt/drug mixtures. Int J Pharm (2002) 0.85

Development and evaluation of sustained release mini-matrices prepared via hot melt extrusion. J Control Release (2003) 0.85

Effect of maltodextrin and superdisintegrant in directly compressible powder mixtures prepared via co-spray drying. Eur J Pharm Biopharm (2007) 0.85

Enteric-coated pellets of F4 fimbriae for oral vaccination of suckling piglets against enterotoxigenic Escherichia coli infections. Vet Immunol Immunopathol (2003) 0.85

Generation of class-selective monoclonal antibodies against the penicillin group. J Agric Food Chem (2001) 0.85

Additive impact of alfacalcidol on bone mineral density and bone strength in alendronate treated postmenopausal women with reduced bone mass. J Musculoskelet Neuronal Interact (2011) 0.85

Development of a liquid chromatographic assay for an anti-HIV tablet containing lamivudine, zidovudine and TMC278.HCL. J Pharm Biomed Anal (2008) 0.84

Pharmaceutical aspects of drug eluting stents. J Pharm Sci (2008) 0.84

Chemoprophylaxis of trypanosomiasis, due to Trypanosoma (Nannomonas) congolense, in rabbits using a slow release device containing homidium bromide. Ann Soc Belg Med Trop (1989) 0.84