Published in J Org Chem on July 17, 2009
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Synthesis of oligonucleotide glycoconjugates using sequential click and oximation ligations. Bioconjug Chem (2010) 0.83
Utilization of intrachain 4'-C-azidomethylthymidine for preparation of oligodeoxyribonucleotide conjugates by click chemistry in solution and on a solid support. Bioconjug Chem (2008) 0.82
Solid-supported synthesis and click conjugation of 4'-C-alkyne functionalized oligodeoxyribonucleotides. Bioconjug Chem (2010) 0.82
Hybridization properties of support-bound oligonucleotides: the effect of the site of immobilization on the stability and selectivity of duplex formation. Bioconjug Chem (2003) 0.82
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Solid-supported 2'-O-glycoconjugation of oligonucleotides by azidation and click reactions. Bioconjug Chem (2011) 0.81
Participation of an additional 4'-hydroxymethyl group in the cleavage and isomerization of ribonucleoside 3'-phosphodiesters. Org Biomol Chem (2015) 0.80
An Orthogonally Protected alpha,alpha-bis(aminomethyl)-beta-alanine building block for the construction of glycoconjugates on a solid support. J Org Chem (2002) 0.80
2,6-Bis(functionalized) purines as metal-ion-binding surrogate nucleobases that enhance hybridization with unmodified 2'-O-methyl oligoribonucleotides. Org Biomol Chem (2013) 0.80
Phosphodiester cleavage of ribonucleoside monophosphates and polyribonucleotides by homo- and heterodinuclear metal complexes of a cyclohexane-based polyamino-polyol ligand. Chemistry (2003) 0.79
Stabilisation of the transition state of phosphodiester bond cleavage within linear single-stranded oligoribonucleotides. Org Biomol Chem (2003) 0.79
Di(azacrown) conjugates of 2'-O-methyl oligoribonucleotides as sequence-selective artificial ribonucleases. Bioconjug Chem (2007) 0.79
Solid-phase synthesis of multiantennary oligonucleotide glycoconjugates utilizing on-support oximation. Bioconjug Chem (2004) 0.79
Optimization of the multiple enzymatic activities of the hepatitis C virus NS3 protein. Anal Biochem (2009) 0.79
Acetylated and methylated β-cyclodextrins as viable soluble supports for the synthesis of short 2′-oligodeoxyribo-nucleotides in solution. Molecules (2012) 0.79
Base moiety selectivity in cleavage of short oligoribonucleotides by di- and tri-nuclear Zn(II) complexes of azacrown-derived ligands. Org Biomol Chem (2009) 0.78
Simultaneous interaction with base and phosphate moieties modulates the phosphodiester cleavage of dinucleoside 3',5'-monophosphates by dinuclear Zn2+ complexes of di(azacrown) ligands. J Am Chem Soc (2006) 0.78
The base sequence dependent flexibility of linear single-stranded oligoribonucleotides correlates with the reactivity of the phosphodiester bond. Org Biomol Chem (2003) 0.78
Solid-supported NOTA and DOTA chelators useful for the synthesis of 3'-radiometalated oligonucleotides. Bioconjug Chem (2012) 0.78
Synthesis of N-acetyl-D-galactosamine and folic acid conjugated ribozymes. Bioconjug Chem (2002) 0.78
HCV NS5B polymerase inhibitors 1: Synthesis and in vitro activity of 2-(1,1-dioxo-2H-[1,2,4]benzothiadiazin-3-yl)-1-hydroxynaphthalene derivatives. Bioorg Med Chem Lett (2009) 0.77
Zn2+ complexes of di- and tri-nucleating azacrown ligands as base-moiety-selective cleaving agents of RNA 3',5'-phosphodiester bonds: binding to guanine base. Chembiochem (2008) 0.77
Scaleable and efficient synthesis of 2'-deoxy-2'-N-phthaloyl nucleoside phosphoramidites for oligonucleotide synthesis. Bioorg Med Chem Lett (2002) 0.77
Solid-supported synthesis of cryptand-like macrobicyclic peptides. J Org Chem (2003) 0.77
Reactions of 9-substituted guanines with bromomalondialdehyde in aqueous solution predominantly yield glyoxal-derived adducts. Org Biomol Chem (2004) 0.76
Preparation of azacrown-functionalized 2'-O-methyl oligoribonucleotides, potential artificial RNases. Bioconjug Chem (2004) 0.76
Pentaerythrityltetramine scaffolds for solid-phase combinatorial chemistry. J Org Chem (2004) 0.76
Synthesis and enzymatic deprotection of fully protected 2'-5' oligoadenylates (2-5A): towards a prodrug strategy for short 2-5A. Chem Biodivers (2012) 0.76
A promising approach for treatment of tumor-induced bone diseases: utilizing bisphosphonate derivatives of nucleoside antimetabolites. Bone (2010) 0.75
3-Acetyloxy-2-cyano-2-(alkylaminocarbamoyl)propyl groups as biodegradable protecting groups of nucleoside 5´-mono-phosphates. Molecules (2011) 0.75
Hydrolytic reactions of thymidine 5'-o-phenyl-N-alkylphosphoramidates, models of nucleoside 5'-monophosphate prodrugs. Chemistry (2007) 0.75
2,2-Disubstituted 4-acylthio-3-oxobutyl groups as esterase- and thermolabile protecting groups of phosphodiesters. J Org Chem (2013) 0.75
Chemical and enzymatic stability of amino acid derived phosphoramidates of antiviral nucleoside 5'-monophosphates bearing a biodegradable protecting group. Org Biomol Chem (2010) 0.75
Solid-phase synthesis of 5'-triphosphate 2'-5'-oligoadenylates analogs with 3'-O-biolabile groups and their evaluation as RNase L activators and antiviral drugs. Bioorg Med Chem (2013) 0.75
Synthesis of phosphate-branched oligonucleotides. Bioconjug Chem (2004) 0.75
Synthesis of modified nucleosides for incorporation of formyletheno and carboxyetheno adducts of adenine nucleosides into oligonucleotides. Nucleosides Nucleotides Nucleic Acids (2007) 0.75
Sequence-selective cleavage of oligoribonucleotides by 3d transition metal complexes of 1,5,9-triazacyclododecane-functionalized 2'-O-methyl oligoribonucleotides. Bioconjug Chem (2004) 0.75
Cu2+TerPy complexes as catalysts of the cleavage of the 5'-cap structure of mRNA. Nucleosides Nucleotides Nucleic Acids (2007) 0.75
An aminooxy-functionalized non-nucleosidic phosphoramidite for the construction of multiantennary oligonucleotide glycoconjugates on a solid support. Curr Protoc Nucleic Acid Chem (2005) 0.75
Mixed-phase hybridization of short oligodeoxyribonucleotides on microscopic polymer particles: effect of one-base mismatches on duplex stability. Bioconjug Chem (2002) 0.75
Bimetallic complexes of spiro-azacrown ligands as catalysts of phosphoester and phosphoric anhydride cleavage. Chem Biodivers (2004) 0.75
Synthesis of an oligonucleotide analogue of ethenoadenosine. Nucleosides Nucleotides Nucleic Acids (2003) 0.75
Polyazacyclophanes incorporating two pyridine units and a heteroaromatic pendant group as potential cleaving agents of mRNA 5'-cap structure. Chem Biodivers (2005) 0.75
A comparative study on the cleavage of stereoisomeric uridylyl(3',5')uridines [D,D-, D,L- and L,D-UpU] by acid, base and metal ion catalysts. Orig Life Evol Biosph (2002) 0.75
Synthesis and cellular uptake of fluorescently labeled multivalent hyaluronan disaccharide conjugates of oligonucleotide phosphorothioates. Bioconjug Chem (2008) 0.75
Metal ion complexes of macrocyclic polyamines enhance both the phosphate hydrolysis and imidazole ring opening of RNA 5'-cap structure. Chem Biodivers (2005) 0.75
Selective circular oligonucleotide probes improve detection of point mutations in DNA. Chem Biodivers (2004) 0.75
The cleavage of the triphosphate bridge of a model for the 5'-cap mRNA promoted by dinuclear bicyclic complexes with metal ions. Nucleosides Nucleotides Nucleic Acids (2003) 0.75
Phosphodiester cleavage of guanylyl-(3',3')-(2'-amino-2'-deoxyuridine): rate acceleration by the 2'-amino function. J Am Chem Soc (2005) 0.75
Effective anomerisation of 2'-deoxyadenosine derivatives during disaccharide nucleoside synthesis. Nucleosides Nucleotides Nucleic Acids (2004) 0.75
Intramolecular participation of amino groups in the cleavage and isomerization of ribonucleoside 3'-phosphodiesters: the role in stabilization of the phosphorane intermediate. Chemistry (2013) 0.75
Orthogonally protected cyclo-beta-tetrapeptides as solid-supported scaffolds for the synthesis of glycoclusters. J Org Chem (2006) 0.75
Solid-phase synthesis of 4(5),1',5'-trisubstituted 2,4'-biimidazoles. J Org Chem (2009) 0.75
2,2-Bis(ethoxycarbonyl)- and 2-(alkylaminocarbonyl)-2-cyano-substituted 3-(pivaloyloxy)propyl groups as biodegradable phosphate protections of oligonucleotides. Bioconjug Chem (2005) 0.75
A mixed-phase immunoassay based on simultaneous binding of fluorescently tagged and PNA-conjugated peptide epitopes on antibodies: quantification on PNA-coated microparticles. Bioconjug Chem (2006) 0.75
Synthesis and Anti-HCV Activity of Sugar-Modified Guanosine Analogues: Discovery of AL-611 as HCV NS5B Polymerase Inhibitor for the Treatment of Chronic Hepatitis C. J Med Chem (2020) 0.75
HCV NS5B polymerase inhibitors 2: Synthesis and in vitro activity of (1,1-dioxo-2H-[1,2,4]benzothiadiazin-3-yl) azolo[1,5-a]pyridine and azolo[1,5-a]pyrimidine derivatives. Bioorg Med Chem Lett (2009) 0.75
HCV NS5B polymerase inhibitors 3: Synthesis and in vitro activity of 3-(1,1-dioxo-2H-[1,2,4]benzothiadiazin-3-yl)-4-hydroxy-2H-quinolizin-2-one derivatives. Bioorg Med Chem Lett (2009) 0.75
Solid-phase synthesis of 7-substituted 3H-imidazo[2,1-i]purines. Org Biomol Chem (2006) 0.75
Metal ion promoted cleavage of RNA phosphodiester bonds: from Zn(II) aqua ion to artificial ribonucleases. Nucleic Acids Symp Ser (Oxf) (2007) 0.75
Preparation of hexaaza and heptaaza macrocycles functionalized with a single aminoalkyl pendant arm. Org Biomol Chem (2003) 0.75
Quantification of mixed-phase hybridization on polymer microparticles by europium(III) ion fluorescence. Methods Mol Biol (2007) 0.75
Macrocyclic amines as catalysts of the hydrolysis of the triphosphate bridge of the mRNA 5'-cap structure. Org Biomol Chem (2003) 0.75
Hydrolysis of a mRNA 5'-cap model substrate, 5',5'-ApppA by di- and trinuclear zinc(II) complexes of a polyamino-polyol ligand. J Inorg Biochem (2005) 0.75
The Zn(2+) complex of 1,4,7,10-tetraazacyclododecane as an artificial nucleobase. Nucleosides Nucleotides Nucleic Acids (2011) 0.75
Synthesis and enzymatic deprotection of biodegradably protected dinucleoside-2',5'-monophosphates: 3-(acetyloxy)-2,2-bis(ethoxycarbonyl)propyl phosphoesters of 3'-O-(acyloxymethyl)adenylyl-2',5'-adenosines. Chem Biodivers (2011) 0.75