| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Structural snapshots of human HDAC8 provide insights into the class I histone deacetylases.
|
Structure
|
2004
|
3.31
|
|
2
|
Combining the polymerase incomplete primer extension method for cloning and mutagenesis with microscreening to accelerate structural genomics efforts.
|
Proteins
|
2008
|
3.29
|
|
3
|
Crystal structure of TM1367 from Thermotoga maritima at 1.90 A resolution reveals an atypical member of the cyclophilin (peptidylprolyl isomerase) fold.
|
Proteins
|
2006
|
1.51
|
|
4
|
Structures of the cancer-related Aurora-A, FAK, and EphA2 protein kinases from nanovolume crystallography.
|
Structure
|
2002
|
1.42
|
|
5
|
Gene expression response to misfolded protein as a screen for soluble recombinant protein.
|
Protein Eng
|
2002
|
1.30
|
|
6
|
The self-inhibited structure of full-length PCSK9 at 1.9 A reveals structural homology with resistin within the C-terminal domain.
|
Proc Natl Acad Sci U S A
|
2007
|
1.29
|
|
7
|
Structure of the γ-D-glutamyl-L-diamino acid endopeptidase YkfC from Bacillus cereus in complex with L-Ala-γ-D-Glu: insights into substrate recognition by NlpC/P60 cysteine peptidases.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
1.28
|
|
8
|
Structural basis of murein peptide specificity of a gamma-D-glutamyl-l-diamino acid endopeptidase.
|
Structure
|
2009
|
1.23
|
|
9
|
Crystal structure of the Fic (Filamentation induced by cAMP) family protein SO4266 (gi|24375750) from Shewanella oneidensis MR-1 at 1.6 A resolution.
|
Proteins
|
2009
|
1.14
|
|
10
|
Identification and structural characterization of heme binding in a novel dye-decolorizing peroxidase, TyrA.
|
Proteins
|
2007
|
1.09
|
|
11
|
Crystal structures of two novel dye-decolorizing peroxidases reveal a beta-barrel fold with a conserved heme-binding motif.
|
Proteins
|
2007
|
1.04
|
|
12
|
Crystal structure of acireductone dioxygenase (ARD) from Mus musculus at 2.06 angstrom resolution.
|
Proteins
|
2006
|
1.03
|
|
13
|
The crystal structure of shikimate dehydrogenase (AroE) reveals a unique NADPH binding mode.
|
J Bacteriol
|
2003
|
1.02
|
|
14
|
Structural analysis of papain-like NlpC/P60 superfamily enzymes with a circularly permuted topology reveals potential lipid binding sites.
|
PLoS One
|
2011
|
1.01
|
|
15
|
Crystal structure of the first eubacterial Mre11 nuclease reveals novel features that may discriminate substrates during DNA repair.
|
J Mol Biol
|
2010
|
1.01
|
|
16
|
Structure of a membrane-attack complex/perforin (MACPF) family protein from the human gut symbiont Bacteroides thetaiotaomicron.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
0.98
|
|
17
|
Structure of an essential bacterial protein YeaZ (TM0874) from Thermotoga maritima at 2.5 Å resolution.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2009
|
0.95
|
|
18
|
The structure of Jann_2411 (DUF1470) from Jannaschia sp. at 1.45 Å resolution reveals a new fold (the ABATE domain) and suggests its possible role as a transcription regulator.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2009
|
0.94
|
|
19
|
The structure of SSO2064, the first representative of Pfam family PF01796, reveals a novel two-domain zinc-ribbon OB-fold architecture with a potential acyl-CoA-binding role.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
0.94
|
|
20
|
Structure of the first representative of Pfam family PF09410 (DUF2006) reveals a structural signature of the calycin superfamily that suggests a role in lipid metabolism.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2009
|
0.89
|
|
21
|
Crystal structure of the ApbE protein (TM1553) from Thermotoga maritima at 1.58 A resolution.
|
Proteins
|
2006
|
0.89
|
|
22
|
Open and closed conformations of two SpoIIAA-like proteins (YP_749275.1 and YP_001095227.1) provide insights into membrane association and ligand binding.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2009
|
0.89
|
|
23
|
Crystal structures of active fully assembled substrate- and product-bound complexes of UDP-N-acetylmuramic acid:L-alanine ligase (MurC) from Haemophilus influenzae.
|
J Bacteriol
|
2003
|
0.89
|
|
24
|
A structural basis for the regulatory inactivation of DnaA.
|
J Mol Biol
|
2008
|
0.87
|
|
25
|
Crystal structure of an ORFan protein (TM1622) from Thermotoga maritima at 1.75 A resolution reveals a fold similar to the Ran-binding protein Mog1p.
|
Proteins
|
2006
|
0.87
|
|
26
|
Structures of three members of Pfam PF02663 (FmdE) implicated in microbial methanogenesis reveal a conserved α+β core domain and an auxiliary C-terminal treble-clef zinc finger.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
0.86
|
|
27
|
Structure of a tryptophanyl-tRNA synthetase containing an iron-sulfur cluster.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
0.86
|
|
28
|
Crystal structure of NMA1982 from Neisseria meningitidis at 1.5 angstroms resolution provides a structural scaffold for nonclassical, eukaryotic-like phosphatases.
|
Proteins
|
2007
|
0.85
|
|
29
|
The structure of the first representative of Pfam family PF06475 reveals a new fold with possible involvement in glycolipid metabolism.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2009
|
0.85
|
|
30
|
Structure of the pilus assembly protein TadZ from Eubacterium rectale: implications for polar localization.
|
Mol Microbiol
|
2012
|
0.85
|
|
31
|
Crystal structure of homoserine O-succinyltransferase from Bacillus cereus at 2.4 A resolution.
|
Proteins
|
2007
|
0.85
|
|
32
|
Bacterial pleckstrin homology domains: a prokaryotic origin for the PH domain.
|
J Mol Biol
|
2009
|
0.85
|
|
33
|
Conformational changes associated with the binding of zinc acetate at the putative active site of XcTcmJ, a cupin from Xanthomonas campestris pv. campestris.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2009
|
0.84
|
|
34
|
A conserved fold for fimbrial components revealed by the crystal structure of a putative fimbrial assembly protein (BT1062) from Bacteroides thetaiotaomicron at 2.2 Å resolution.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
0.84
|
|
35
|
Crystal structure of AICAR transformylase IMP cyclohydrolase (TM1249) from Thermotoga maritima at 1.88 A resolution.
|
Proteins
|
2008
|
0.83
|
|
36
|
Structural and functional characterizations of SsgB, a conserved activator of developmental cell division in morphologically complex actinomycetes.
|
J Biol Chem
|
2009
|
0.83
|
|
37
|
Insights into substrate specificity of geranylgeranyl reductases revealed by the structure of digeranylgeranylglycerophospholipid reductase, an essential enzyme in the biosynthesis of archaeal membrane lipids.
|
J Mol Biol
|
2010
|
0.83
|
|
38
|
Structure of the first representative of Pfam family PF04016 (DUF364) reveals enolase and Rossmann-like folds that combine to form a unique active site with a possible role in heavy-metal chelation.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
0.83
|
|
39
|
Crystal structure of histidine phosphotransfer protein ShpA, an essential regulator of stalk biogenesis in Caulobacter crescentus.
|
J Mol Biol
|
2009
|
0.83
|
|
40
|
Structure of a virulence regulatory factor CvfB reveals a novel winged helix RNA binding module.
|
Structure
|
2010
|
0.82
|
|
41
|
Crystal structure of a single-stranded DNA-binding protein (TM0604) from Thermotoga maritima at 2.60 A resolution.
|
Proteins
|
2006
|
0.82
|
|
42
|
Crystal structure of 2-phosphosulfolactate phosphatase (ComB) from Clostridium acetobutylicum at 2.6 A resolution reveals a new fold with a novel active site.
|
Proteins
|
2006
|
0.82
|
|
43
|
Crystal structure of a novel archaeal AAA+ ATPase SSO1545 from Sulfolobus solfataricus.
|
Proteins
|
2009
|
0.81
|
|
44
|
Structure of a putative NTP pyrophosphohydrolase: YP_001813558.1 from Exiguobacterium sibiricum 255-15.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
0.81
|
|
45
|
The structure of Mlc titration factor A (MtfA/YeeI) reveals a prototypical zinc metallopeptidase related to anthrax lethal factor.
|
J Bacteriol
|
2012
|
0.80
|
|
46
|
Structures of the first representatives of Pfam family PF06938 (DUF1285) reveal a new fold with repeated structural motifs and possible involvement in signal transduction.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
0.80
|
|
47
|
Structural and sequence analysis of imelysin-like proteins implicated in bacterial iron uptake.
|
PLoS One
|
2011
|
0.80
|
|
48
|
Crystal structures of MW1337R and lin2004: representatives of a novel protein family that adopt a four-helical bundle fold.
|
Proteins
|
2008
|
0.80
|
|
49
|
Structure and function of a novel LD-carboxypeptidase a involved in peptidoglycan recycling.
|
J Bacteriol
|
2013
|
0.79
|
|
50
|
Structure of an MmyB-like regulator from C. aurantiacus, member of a new transcription factor family linked to antibiotic metabolism in actinomycetes.
|
PLoS One
|
2012
|
0.79
|
|
51
|
Comparative structural analysis of a novel glutathioneS-transferase (ATU5508) from Agrobacterium tumefaciens at 2.0 A resolution.
|
Proteins
|
2006
|
0.79
|
|
52
|
The structure of BVU2987 from Bacteroides vulgatus reveals a superfamily of bacterial periplasmic proteins with possible inhibitory function.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
0.79
|
|
53
|
Crystal structure of a novel Sm-like protein of putative cyanophage origin at 2.60 A resolution.
|
Proteins
|
2009
|
0.79
|
|
54
|
Crystal structure of MtnX phosphatase from Bacillus subtilis at 2.0 angstroms resolution provides a structural basis for bipartite phosphomonoester hydrolysis of 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate.
|
Proteins
|
2007
|
0.79
|
|
55
|
Structure and function of the DUF2233 domain in bacteria and in the human mannose 6-phosphate uncovering enzyme.
|
J Biol Chem
|
2013
|
0.78
|
|
56
|
Crystal structure of TM1030 from Thermotoga maritima at 2.3 A resolution reveals molecular details of its transcription repressor function.
|
Proteins
|
2007
|
0.78
|
|
57
|
The structure of KPN03535 (gi|152972051), a novel putative lipoprotein from Klebsiella pneumoniae, reveals an OB-fold.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2009
|
0.78
|
|
58
|
The structure of the first representative of Pfam family PF09836 reveals a two-domain organization and suggests involvement in transcriptional regulation.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2009
|
0.78
|
|
59
|
Structure and function of the first full-length murein peptide ligase (Mpl) cell wall recycling protein.
|
PLoS One
|
2011
|
0.78
|
|
60
|
Structure of LP2179, the first representative of Pfam family PF08866, suggests a new fold with a role in amino-acid metabolism.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2009
|
0.77
|
|
61
|
The structure of Haemophilus influenzae prephenate dehydrogenase suggests unique features of bifunctional TyrA enzymes.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
0.77
|
|
62
|
Crystal structure of a putative quorum sensing-regulated protein (PA3611) from the Pseudomonas-specific DUF4146 family.
|
Proteins
|
2013
|
0.76
|
|
63
|
The crystal structure of a bacterial Sufu-like protein defines a novel group of bacterial proteins that are similar to the N-terminal domain of human Sufu.
|
Protein Sci
|
2010
|
0.76
|
|
64
|
Structure of Bacteroides thetaiotaomicron BT2081 at 2.05 Å resolution: the first structural representative of a new protein family that may play a role in carbohydrate metabolism.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
0.76
|
|
65
|
Structure of BT_3984, a member of the SusD/RagB family of nutrient-binding molecules.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
0.76
|
|
66
|
Structures of the first representatives of Pfam family PF06684 (DUF1185) reveal a novel variant of the Bacillus chorismate mutase fold and suggest a role in amino-acid metabolism.
|
Acta Crystallogr Sect F Struct Biol Cryst Commun
|
2010
|
0.75
|
|
67
|
Molecular characterization of novel pyridoxal-5'-phosphate-dependent enzymes from the human microbiome.
|
Protein Sci
|
2014
|
0.75
|
|
68
|
Crystal structure of a member of a novel family of dioxygenases (PF10014) reveals a conserved cupin fold and active site.
|
Proteins
|
2013
|
0.75
|
|
69
|
Time-resolved fluorescence resonance energy transfer and surface plasmon resonance-based assays for retinoid and transthyretin binding to retinol-binding protein 4.
|
Anal Biochem
|
2009
|
0.75
|