Published in Toxicol Sci on May 29, 2009
Endocrine-disrupting chemicals and public health protection: a statement of principles from The Endocrine Society. Endocrinology (2012) 3.98
Transgenerational effects of di-(2-ethylhexyl) phthalate on testicular germ cell associations and spermatogonial stem cells in mice. Biol Reprod (2013) 1.16
Determination of the di-(2-ethylhexyl) phthalate NOAEL for reproductive development in the rat: importance of the retention of extra animals to adulthood. Toxicol Sci (2010) 1.10
Reproductive and developmental effects of phthalate diesters in females. Crit Rev Toxicol (2013) 1.03
Organic and inorganic mercury in neonatal rat brain after prenatal exposure to methylmercury and mercury vapor. Environ Health Perspect (2010) 0.97
Dipentyl phthalate dosing during sexual differentiation disrupts fetal testis function and postnatal development of the male Sprague-Dawley rat with greater relative potency than other phthalates. Toxicol Sci (2010) 0.93
Reproductive effects in F1 adult females exposed in utero to moderate to high doses of mono-2-ethylhexylphthalate (MEHP). Reprod Toxicol (2012) 0.92
Dose Addition Models Based on Biologically Relevant Reductions in Fetal Testosterone Accurately Predict Postnatal Reproductive Tract Alterations by a Phthalate Mixture in Rats. Toxicol Sci (2015) 0.80
Man is not a big rat: concerns with traditional human risk assessment of phthalates based on their anti-androgenic effects observed in the rat foetus. Basic Clin Androl (2014) 0.80
Establishing the "Biological Relevance" of Dipentyl Phthalate Reductions in Fetal Rat Testosterone Production and Plasma and Testis Testosterone Levels. Toxicol Sci (2015) 0.76
In Utero and Lactational Exposure Study in Rats to Identify Replacements for Di(2-ethylhexyl) Phthalate. Sci Rep (2017) 0.75
Cumulative effects of antiandrogenic chemical mixtures and their relevance to human health risk assessment. Int J Hyg Environ Health (2016) 0.75
Do endocrine disruptors cause hypospadias? Transl Androl Urol (2014) 0.75
Decrease in anogenital distance among male infants with prenatal phthalate exposure. Environ Health Perspect (2005) 7.43
Effects of study duration, frequency of observation, and sample size on power in studies of group differences in polynomial change. Psychol Methods (2001) 3.68
The plasticizer diethylhexyl phthalate induces malformations by decreasing fetal testosterone synthesis during sexual differentiation in the male rat. Toxicol Sci (2000) 3.46
Perinatal exposure to the phthalates DEHP, BBP, and DINP, but not DEP, DMP, or DOTP, alters sexual differentiation of the male rat. Toxicol Sci (2000) 3.45
Human breast milk contamination with phthalates and alterations of endogenous reproductive hormones in infants three months of age. Environ Health Perspect (2006) 2.73
Male reproductive tract malformations in rats following gestational and lactational exposure to Di(n-butyl) phthalate: an antiandrogenic mechanism? Toxicol Sci (1998) 2.53
In utero exposure to di-(2-ethylhexyl)phthalate and duration of human pregnancy. Environ Health Perspect (2003) 2.49
Dose-dependent alterations in androgen-regulated male reproductive development in rats exposed to Di(n-butyl) phthalate during late gestation. Toxicol Sci (2000) 2.19
Human 'testicular dysgenesis syndrome': a possible model using in-utero exposure of the rat to dibutyl phthalate. Hum Reprod (2003) 2.12
Effects of phthalate esters on the developing reproductive tract of male rats. Hum Reprod Update (2001) 1.89
Fifteen years after "Wingspread"--environmental endocrine disrupters and human and wildlife health: where we are today and where we need to go. Toxicol Sci (2008) 1.71
Decreased serum free testosterone in workers exposed to high levels of di-n-butyl phthalate (DBP) and di-2-ethylhexyl phthalate (DEHP): a cross-sectional study in China. Environ Health Perspect (2006) 1.60
Adverse effects of environmental antiandrogens and androgens on reproductive development in mammals. Int J Androl (2006) 1.57
Association between prenatal exposure to phthalates and the health of newborns. Environ Int (2008) 1.51
Detection of phthalate metabolites in human amniotic fluid. Bull Environ Contam Toxicol (2004) 1.44
Cumulative effects of dibutyl phthalate and diethylhexyl phthalate on male rat reproductive tract development: altered fetal steroid hormones and genes. Toxicol Sci (2007) 1.41
Phthalate ester-induced gubernacular lesions are associated with reduced insl3 gene expression in the fetal rat testis. Toxicol Lett (2004) 1.39
Effect of butyl benzyl phthalate in Sprague-Dawley rats after gavage administration: a two-generation reproductive study. Reprod Toxicol (2000) 1.38
A dose-response study following in utero and lactational exposure to di-(2-ethylhexyl)-phthalate (DEHP): non-monotonic dose-response and low dose effects on rat brain aromatase activity. Toxicology (2006) 1.36
Phthalate-induced Leydig cell hyperplasia is associated with multiple endocrine disturbances. Proc Natl Acad Sci U S A (2004) 1.35
Relationship between androgen action in the "male programming window," fetal sertoli cell number, and adult testis size in the rat. Endocrinology (2008) 1.34
A mixture of the "antiandrogens" linuron and butyl benzyl phthalate alters sexual differentiation of the male rat in a cumulative fashion. Biol Reprod (2004) 1.30
Mechanisms underlying the anti-androgenic effects of diethylhexyl phthalate in fetal rat testis. Toxicology (2006) 1.29
Effects of monobutyl and di(n-butyl) phthalate in vitro on steroidogenesis and Leydig cell aggregation in fetal testis explants from the rat: comparison with effects in vivo in the fetal rat and neonatal marmoset and in vitro in the human. Environ Health Perspect (2006) 1.27
Oral toxicity of bis(2-ethylhexyl) phthalate during pregnancy and suckling in the Long-Evans rat. Food Chem Toxicol (1998) 1.26
Testicular dysgenesis syndrome: foetal origin of adult reproductive problems. Clin Endocrinol (Oxf) (2009) 1.25
Possible impact of phthalates on infant reproductive health. Int J Androl (2006) 1.22
Age-dependent response of the rat testes to di(2-ethylhexyl) phthalate. Environ Health Perspect (1986) 1.17
A dose-response analysis of the reproductive effects of a single gestational dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin in male Long Evans Hooded rat offspring. Toxicol Appl Pharmacol (1997) 1.12
Determination of the di-(2-ethylhexyl) phthalate NOAEL for reproductive development in the rat: importance of the retention of extra animals to adulthood. Toxicol Sci (2010) 1.10
Effects of dibutyl phthalate in male rabbits following in utero, adolescent, or postpubertal exposure. Toxicol Sci (2003) 1.06
Antiandrogenic effects in male rats perinatally exposed to a mixture of di(2-ethylhexyl) phthalate and di(2-ethylhexyl) adipate. Reprod Toxicol (2005) 1.06
A dose response study following in utero and lactational exposure to di-(2-ethylhexyl) phthalate (DEHP): reproductive effects on adult male offspring rats. Toxicology (2006) 1.03
Phthalate exposure during pregnancy and lower anogenital index in boys: wider implications for the general population? Environ Health Perspect (2005) 1.02
Testicular toxicity and reduced Sertoli cell numbers in neonatal rats by di(2-ethylhexyl)phthalate and the recovery of fertility as adults. Toxicol Appl Pharmacol (1988) 1.02
Steroidogenesis in fetal male rats is reduced by DEHP and DINP, but endocrine effects of DEHP are not modulated by DEHA in fetal, prepubertal and adult male rats. Reprod Toxicol (2004) 0.99
Endocrine disrupters and testicular dysgenesis syndrome. Horm Res (2002) 0.99
Species differences in the testicular toxicity of phthalate esters. Toxicol Lett (1982) 0.99
Developmental toxicity evaluation of dietary di(2-ethylhexyl)phthalate in Fischer 344 rats and CD-1 mice. Fundam Appl Toxicol (1988) 0.98
Urinary and amniotic fluid levels of phthalate monoesters in rats after the oral administration of di(2-ethylhexyl) phthalate and di-n-butyl phthalate. Toxicology (2005) 0.98
Studies on the effects of orally administered Di-(2-ethylhexyl) phthalate in the ferret. Toxicology (1977) 0.97
A dose-response study following in utero and lactational exposure to di(2-ethylhexyl)phthalate: effects on female rat reproductive development. Toxicol Sci (2006) 0.94
Early testicular effects in rats perinatally exposed to DEHP in combination with DEHA--apoptosis assessment and immunohistochemical studies. Reprod Toxicol (2005) 0.93
A dose-response study following in utero and lactational exposure to di-(2-ethylhexyl) phthalate (DEHP): reproductive effects on adult female offspring rats. Toxicology (2006) 0.92
Differential expression of the phthalate syndrome in male Sprague-Dawley and Wistar rats after in utero DEHP exposure. Toxicol Lett (2007) 0.90
Effect of di(2-ethylhexyl) phthalate (DEHP) on genital organs from juvenile common marmosets: I. Morphological and biochemical investigation in 65-week toxicity study. J Toxicol Environ Health A (2006) 0.85
Influence of di-(2-ethylhexyl)phthalate on fetal testicular development by oral administration to pregnant rats. J Toxicol Sci (2005) 0.80
NTP-CERHR Monograph on the Potential Human Reproductive and Developmental Effects of Di-n-Octyl Phthalate (DnOP). NTP CERHR MON (2003) 0.80
Strain differences in susceptibility to di-2-ethylhexyl phthalate-induced testicular atrophy in mice. Toxicol Lett (1993) 0.77
Evaluation of reproductive development following intravenous and oral exposure to DEHP in male neonatal rats. Int J Toxicol (2003) 0.77
[Di(2-ethylhexyl) phthalate affects the testes and leydig cells of neonatal KM mice]. Zhonghua Nan Ke Xue (2006) 0.77
Estrogenic chemicals in plastic and oral contraceptives disrupt development of the fetal mouse prostate and urethra. Proc Natl Acad Sci U S A (2005) 2.35
Fifteen years after "Wingspread"--environmental endocrine disrupters and human and wildlife health: where we are today and where we need to go. Toxicol Sci (2008) 1.71
Exposure to a low dose of bisphenol A during fetal life or in adulthood alters maternal behavior in mice. Environ Health Perspect (2002) 1.64
Effects of in utero exposure to finasteride on androgen-dependent reproductive development in the male rat. Toxicol Sci (2003) 1.49
Male rats exposed to linuron in utero exhibit permanent changes in anogenital distance, nipple retention, and epididymal malformations that result in subsequent testicular atrophy. Toxicol Sci (2002) 1.19
Low phytoestrogen levels in feed increase fetal serum estradiol resulting in the "fetal estrogenization syndrome" and obesity in CD-1 mice. Environ Health Perspect (2008) 1.15
Prenatal testosterone exposure permanently masculinizes anogenital distance, nipple development, and reproductive tract morphology in female Sprague-Dawley rats. Toxicol Sci (2007) 1.10
Effects of prenatal testosterone propionate on the sexual development of male and female rats: a dose-response study. Toxicol Sci (2002) 1.08
Cumulative effects of in utero administration of mixtures of "antiandrogens" on male rat reproductive development. Toxicol Pathol (2009) 1.01
A role for basic transcription element-binding protein 1 (BTEB1) in the autoinduction of thyroid hormone receptor beta. J Biol Chem (2007) 1.00
Recommended approaches for the evaluation of testicular and epididymal toxicity. Toxicol Pathol (2002) 0.90
Differential expression of the phthalate syndrome in male Sprague-Dawley and Wistar rats after in utero DEHP exposure. Toxicol Lett (2007) 0.90
Pubertal administration of DEHP delays puberty, suppresses testosterone production, and inhibits reproductive tract development in male Sprague-Dawley and Long-Evans rats. Toxicol Sci (2009) 0.89
Effects of in utero exposure to the organophosphate insecticide fenitrothion on androgen-dependent reproductive development in the Crl:CD(SD)BR rat. Toxicol Sci (2002) 0.89
Prochloraz inhibits testosterone production at dosages below those that affect androgen-dependent organ weights or the onset of puberty in the male Sprague Dawley rat. Toxicol Sci (2007) 0.86
Altered gene expression during rat Wolffian duct development in response to in utero exposure to the antiandrogen linuron. Toxicol Sci (2003) 0.86
In utero phthalate effects in the female rat: a model for MRKH syndrome. Toxicol Lett (2013) 0.85
The herbicide linuron reduces testosterone production from the fetal rat testis during both in utero and in vitro exposures. Toxicol Lett (2009) 0.84
Sensitivity of fetal rat testicular steroidogenesis to maternal prochloraz exposure and the underlying mechanism of inhibition. Toxicol Sci (2007) 0.84
Altered gene expression during rat Wolffian duct development following di(n-butyl) phthalate exposure. Toxicol Sci (2005) 0.84
Hershberger assay to investigate the effects of endocrine-disrupting compounds with androgenic or antiandrogenic activity in castrate-immature male rats. Curr Protoc Toxicol (2005) 0.83
Effects of in utero linuron exposure on rat Wolffian duct development. Reprod Toxicol (2002) 0.80
The effect of commonly used vehicles on canine hematology and clinical chemistry values. J Am Assoc Lab Anim Sci (2006) 0.75