Published in Pharmacol Ther on May 30, 2009
Nitric oxide and redox mechanisms in the immune response. J Leukoc Biol (2011) 1.97
The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxid Redox Signal (2010) 1.72
Application of medical gases in the field of neurobiology. Med Gas Res (2011) 1.64
Interactions of multiple gas-transducing systems: hallmarks and uncertainties of CO, NO, and H2S gas biology. Antioxid Redox Signal (2010) 1.63
Chemical characterization of the smallest S-nitrosothiol, HSNO; cellular cross-talk of H2S and S-nitrosothiols. J Am Chem Soc (2012) 1.46
H2S and its role in redox signaling. Biochim Biophys Acta (2014) 1.44
cGMP-dependent protein kinase contributes to hydrogen sulfide-stimulated vasorelaxation. PLoS One (2012) 1.12
Oxygen/ozone as a medical gas mixture. A critical evaluation of the various methods clarifies positive and negative aspects. Med Gas Res (2011) 1.04
Carboxyhemoglobin levels in medical intensive care patients: a retrospective, observational study. Crit Care (2012) 1.04
Sulfur as a signaling nutrient through hydrogen sulfide. Annu Rev Nutr (2014) 1.04
Resolution of inflammation: a new therapeutic frontier. Nat Rev Drug Discov (2016) 1.02
Hydrogen sulfide activates Ca²⁺ sparks to induce cerebral arteriole dilatation. J Physiol (2012) 1.00
Mechanism of vasorelaxation and role of endogenous hydrogen sulfide production in mouse aorta. Naunyn Schmiedebergs Arch Pharmacol (2011) 0.99
Hydrogen sulfide dilates cerebral arterioles by activating smooth muscle cell plasma membrane KATP channels. Am J Physiol Heart Circ Physiol (2011) 0.96
Potential biological chemistry of hydrogen sulfide (H2S) with the nitrogen oxides. Free Radic Biol Med (2012) 0.95
Hydrogen sulfide generated by L-cysteine desulfhydrase acts upstream of nitric oxide to modulate abscisic acid-dependent stomatal closure. Plant Physiol (2014) 0.94
Redox modulation of HMGB1-related signaling. Antioxid Redox Signal (2013) 0.94
Hydrogen sulfide improves wound healing via restoration of endothelial progenitor cell functions and activation of angiopoietin-1 in type 2 diabetes. Diabetes (2014) 0.88
Role of hydrogen sulfide in the pathology of inflammation. Scientifica (Cairo) (2012) 0.87
Hydrogen sulfide and translational medicine. Acta Pharmacol Sin (2013) 0.86
Interplay of hydrogen sulfide and nitric oxide on the pacemaker activity of interstitial cells of cajal from mouse small intestine. Chonnam Med J (2011) 0.85
TRPV1 and SP: key elements for sepsis outcome? Br J Pharmacol (2013) 0.85
The vasorelaxing effect of hydrogen sulfide on isolated rat aortic rings versus pulmonary artery rings. Acta Pharmacol Sin (2011) 0.84
Central modulation of cyclosporine-induced hypertension. Naunyn Schmiedebergs Arch Pharmacol (2014) 0.83
Nitric oxide reduces sickle hemoglobin polymerization: potential role of nitric oxide-induced charge alteration in depolymerization. Arch Biochem Biophys (2011) 0.82
Hydrogen sulphide-induced relaxation of porcine peripheral bronchioles. Br J Pharmacol (2013) 0.81
NO* binds human cystathionine β-synthase quickly and tightly. J Biol Chem (2014) 0.81
Garlic extracts prevent oxidative stress, hypertrophy and apoptosis in cardiomyocytes: a role for nitric oxide and hydrogen sulfide. BMC Complement Altern Med (2012) 0.81
Alternative functions of the brain transsulfuration pathway represent an underappreciated aspect of brain redox biochemistry with significant potential for therapeutic engagement. Free Radic Biol Med (2014) 0.81
Designed iron carbonyls as carbon monoxide (CO) releasing molecules: rapid CO release and delivery to myoglobin in aqueous buffer, and vasorelaxation of mouse aorta. Inorg Chem (2011) 0.80
Gasotransmitters, poisons, and antimicrobials: it's a gas, gas, gas! F1000Prime Rep (2013) 0.80
Hydrogen sulfide regulates Ca(2+) homeostasis mediated by concomitantly produced nitric oxide via a novel synergistic pathway in exocrine pancreas. Antioxid Redox Signal (2013) 0.79
Beneficial effects of diminished production of hydrogen sulfide or carbon monoxide on hypertension and renal injury induced by NO withdrawal. Br J Pharmacol (2014) 0.79
Investigation of hydrogen sulfide gas as a treatment against P. falciparum, murine cerebral malaria, and the importance of thiolation state in the development of cerebral malaria. PLoS One (2013) 0.79
Regulation and role of endogenously produced hydrogen sulfide in angiogenesis. Pharmacol Res (2016) 0.79
Recent advances in the chemical biology of nitroxyl (HNO) detection and generation. Nitric Oxide (2016) 0.78
Hydrogen sulphide-releasing diclofenac derivatives inhibit breast cancer-induced osteoclastogenesis in vitro and prevent osteolysis ex vivo. Br J Pharmacol (2012) 0.78
Analysis of cardiovascular responses to the H2S donors Na2S and NaHS in the rat. Am J Physiol Heart Circ Physiol (2015) 0.78
Correlation between anthropometric measurement, lipid profile, dietary vitamins, serum antioxidants, lipoprotein (a) and lipid peroxides in known cases of 345 elderly hypertensive South Asian aged 56-64 y-A hospital based study. Asian Pac J Trop Biomed (2014) 0.78
Sulfane sustains vascular health: insights into cystathionine γ-lyase function. Circulation (2013) 0.77
Sulfurous gases as biological messengers and toxins: comparative genetics of their metabolism in model organisms. J Toxicol (2011) 0.77
Carbon monoxide affects electrical and contractile activity of rat myocardium. J Biomed Sci (2011) 0.77
Hydrogen sulphide exacerbates acute pancreatitis by over-activating autophagy via AMPK/mTOR pathway. J Cell Mol Med (2016) 0.76
The Role of Hydrogen Sulfide in Renal System. Front Pharmacol (2016) 0.75
The role of hydrogen sulfide in aging and age-related pathologies. Aging (Albany NY) (2016) 0.75
H2S regulates endothelial nitric oxide synthase protein stability by promoting microRNA-455-3p expression. Sci Rep (2017) 0.75
The antioxidative properties of S-allyl cysteine not only influence somatic cells but also improve early embryo cleavage in pigs. PeerJ (2016) 0.75
Nitrosopersulfide (SSNO(-)) decomposes in the presence of sulfide, cyanide or glutathione to give HSNO/SNO(-): consequences for the assumed role in cell signalling. Interface Focus (2017) 0.75
Impairment of nitric oxide synthase but not heme oxygenase accounts for baroreflex dysfunction caused by chronic nicotine in female rats. PLoS One (2014) 0.75
Cystathionine gamma-lyase of perivascular adipose tissue with reversed regulatory effect in diabetic rat artery. Biotechnol Biotechnol Equip (2014) 0.75
The Influence of Smoking on the Variations in Carboxyhemoglobin and Methemoglobin During Urologic Surgery. Med Arch (2017) 0.75
The Role of Hydrogen Sulfide on Cardiovascular Homeostasis: An Overview with Update on Immunomodulation. Front Pharmacol (2017) 0.75
Changes in the electrical and contractile activities of rat atrial myocardium caused by carbon monoxide. Dokl Biol Sci (2011) 0.75
Suppression of phosphorylated MAPK and caspase 3 by carbon dioxide. Mol Cell Biochem (2017) 0.75
Modulation of sinoatrial node pacemaker activity by carbon monoxide and hydrogen sulfide. Dokl Biol Sci (2014) 0.75
Hydrogen sulfide and cell signaling. Annu Rev Pharmacol Toxicol (2011) 3.50
Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse. FASEB J (2005) 3.23
Characterization of a novel, water-soluble hydrogen sulfide-releasing molecule (GYY4137): new insights into the biology of hydrogen sulfide. Circulation (2008) 2.74
The novel neuromodulator hydrogen sulfide: an endogenous peroxynitrite 'scavenger'? J Neurochem (2004) 2.50
Role of hydrogen sulphide in haemorrhagic shock in the rat: protective effect of inhibitors of hydrogen sulphide biosynthesis. Br J Pharmacol (2004) 2.09
Role of hydrogen sulfide in acute pancreatitis and associated lung injury. FASEB J (2005) 1.99
Hydrogen sulfide and its possible roles in myocardial ischemia in experimental rats. J Appl Physiol (1985) (2006) 1.84
Evidence for the formation of a novel nitrosothiol from the gaseous mediators nitric oxide and hydrogen sulphide. Biochem Biophys Res Commun (2006) 1.82
The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxid Redox Signal (2010) 1.72
S-allylcysteine mediates cardioprotection in an acute myocardial infarction rat model via a hydrogen sulfide-mediated pathway. Am J Physiol Heart Circ Physiol (2007) 1.72
Intestinal microbiota determine severity of myocardial infarction in rats. FASEB J (2012) 1.71
GYY4137, a novel hydrogen sulfide-releasing molecule, protects against endotoxic shock in the rat. Free Radic Biol Med (2009) 1.63
Hydrogen sulfide attenuates lipopolysaccharide-induced inflammation by inhibition of p38 mitogen-activated protein kinase in microglia. J Neurochem (2006) 1.61
Hydrogen sulphide: a novel endogenous gasotransmitter facilitates erectile function. J Sex Med (2007) 1.59
Human thrombopoietin reduces myocardial infarct size, apoptosis, and stunning following ischaemia/reperfusion in rats. Cardiovasc Res (2007) 1.52
Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Nat Prod Rep (2005) 1.51
Cardioprotection induced by hydrogen sulfide preconditioning involves activation of ERK and PI3K/Akt pathways. Pflugers Arch (2007) 1.48
Hydrogen sulphide: a novel inhibitor of hypochlorous acid-mediated oxidative damage in the brain? Biochem Biophys Res Commun (2005) 1.48
Hydrogen sulphide is a mediator of carrageenan-induced hindpaw oedema in the rat. Br J Pharmacol (2005) 1.47
Hydrogen sulfide is a mediator of cerebral ischemic damage. Stroke (2006) 1.46
Inhibition of endogenous hydrogen sulfide formation reduces the organ injury caused by endotoxemia. Br J Pharmacol (2005) 1.45
Role of hydrogen sulfide in cecal ligation and puncture-induced sepsis in the mouse. Am J Physiol Lung Cell Mol Physiol (2006) 1.42
Hydrogen sulfide and the vasculature: a novel vasculoprotective entity and regulator of nitric oxide bioavailability? J Cell Mol Med (2009) 1.38
Hydrogen sulphide--a novel mediator of inflammation? Curr Opin Pharmacol (2006) 1.38
Streptozotocin-induced diabetes in the rat is associated with enhanced tissue hydrogen sulfide biosynthesis. Biochem Biophys Res Commun (2005) 1.32
SCH 79797, a selective PAR1 antagonist, limits myocardial ischemia/reperfusion injury in rat hearts. Basic Res Cardiol (2007) 1.30
Hydrogen sulfide induces the synthesis of proinflammatory cytokines in human monocyte cell line U937 via the ERK-NF-kappaB pathway. J Leukoc Biol (2007) 1.30
Nitrite confers protection against myocardial infarction: role of xanthine oxidoreductase, NADPH oxidase and K(ATP) channels. J Mol Cell Cardiol (2007) 1.30
Mechanisms by which epoxyeicosatrienoic acids (EETs) elicit cardioprotection in rat hearts. J Mol Cell Cardiol (2007) 1.24
Differential effects of sulforaphane on histone deacetylases, cell cycle arrest and apoptosis in normal prostate cells versus hyperplastic and cancerous prostate cells. Mol Nutr Food Res (2011) 1.22
Metabolism and tissue distribution of sulforaphane in Nrf2 knockout and wild-type mice. Pharm Res (2011) 1.21
Contractile and vasorelaxant effects of hydrogen sulfide and its biosynthesis in the human internal mammary artery. J Pharmacol Exp Ther (2007) 1.20
Hydrogen sulfide acts as an inflammatory mediator in cecal ligation and puncture-induced sepsis in mice by upregulating the production of cytokines and chemokines via NF-kappaB. Am J Physiol Lung Cell Mol Physiol (2007) 1.19
Inhibiting protease-activated receptor 4 limits myocardial ischemia/reperfusion injury in rat hearts by unmasking adenosine signaling. J Pharmacol Exp Ther (2007) 1.16
Structural basis for the inhibition mechanism of human cystathionine gamma-lyase, an enzyme responsible for the production of H(2)S. J Biol Chem (2008) 1.15
Mechanism of induction of pancreatic acinar cell apoptosis by hydrogen sulfide. Am J Physiol Cell Physiol (2006) 1.10
Hydrogen sulfide acts as a mediator of inflammation in acute pancreatitis: in vitro studies using isolated mouse pancreatic acinar cells. J Cell Mol Med (2007) 1.09
Hydrogen sulphide regulates calcium homeostasis in microglial cells. Glia (2006) 1.09
Role of substance P in hydrogen sulfide-induced pulmonary inflammation in mice. Am J Physiol Lung Cell Mol Physiol (2006) 1.09
The hydrogen sulfide donor, GYY4137, exhibits anti-atherosclerotic activity in high fat fed apolipoprotein E(-/-) mice. Br J Pharmacol (2013) 1.02
Hydrogen sulphide regulates intracellular pH in vascular smooth muscle cells. Biochem Biophys Res Commun (2007) 1.00
Treatment with H2S-releasing diclofenac protects mice against acute pancreatitis-associated lung injury. Shock (2008) 1.00
Effect of S-diclofenac, a novel hydrogen sulfide releasing derivative, on carrageenan-induced hindpaw oedema formation in the rat. Eur J Pharmacol (2007) 0.99
Dexamethasone inhibits lipopolysaccharide-induced hydrogen sulphide biosynthesis in intact cells and in an animal model of endotoxic shock. J Cell Mol Med (2009) 0.98
Site-directed mutagenesis on human cystathionine-gamma-lyase reveals insights into the modulation of H2S production. J Mol Biol (2009) 0.98
Inhibition of hydrogen sulfide synthesis attenuates chemokine production and protects mice against acute pancreatitis and associated lung injury. Pancreas (2008) 0.98
Bioavailability and inter-conversion of sulforaphane and erucin in human subjects consuming broccoli sprouts or broccoli supplement in a cross-over study design. Pharmacol Res (2011) 0.96
Hydrogen sulphide reduces insulin secretion from HIT-T15 cells by a KATP channel-dependent pathway. J Endocrinol (2007) 0.96
Activation of kappa-opioid receptors at reperfusion affords cardioprotection in both rat and mouse hearts. Basic Res Cardiol (2008) 0.96
The complex effects of the slow-releasing hydrogen sulfide donor GYY4137 in a model of acute joint inflammation and in human cartilage cells. J Cell Mol Med (2013) 0.95
Hydrogen sulfide induced neuronal death occurs via glutamate receptor and is associated with calpain activation and lysosomal rupture in mouse primary cortical neurons. Neuropharmacology (2007) 0.95
Evidence for a role of opioids in epoxyeicosatrienoic acid-induced cardioprotection in rat hearts. Am J Physiol Heart Circ Physiol (2010) 0.95
Possible role for the novel gasotransmitter hydrogen sulphide in erectile dysfunction--a pilot study. Eur J Pharmacol (2006) 0.92
Absorption and chemopreventive targets of sulforaphane in humans following consumption of broccoli sprouts or a myrosinase-treated broccoli sprout extract. Mol Nutr Food Res (2015) 0.92
Hydrogen sulfide is an endogenous regulator of aging in Caenorhabditis elegans. Antioxid Redox Signal (2013) 0.92
Nitric oxide-releasing flurbiprofen reduces formation of proinflammatory hydrogen sulfide in lipopolysaccharide-treated rat. Br J Pharmacol (2006) 0.89
Parstatin: a cryptic peptide involved in cardioprotection after ischaemia and reperfusion injury. Cardiovasc Res (2009) 0.88
Cardioprotective effects of nitric oxide-aspirin in myocardial ischemia-reperfused rats. Am J Physiol Heart Circ Physiol (2007) 0.85
C. elegans aging is modulated by hydrogen sulfide and the sulfhydrylase/cysteine synthase cysl-2. PLoS One (2013) 0.84
Effect of nitric oxide releasing paracetamol and flurbiprofen on cytokine production in human blood. Eur J Pharmacol (2004) 0.83
Initial characterization of hydrogen sulfide effects in female sexual function. J Sex Med (2009) 0.82
Multifaceted role of nitric oxide in an in vitro mouse neuronal injury model: transcriptomic profiling defines the temporal recruitment of death signalling cascades. J Cell Mol Med (2012) 0.82
Proteasome inhibition: an early or late event in nitric oxide-induced neuronal death? Nitric Oxide (2007) 0.81
Gadolinium limits myocardial infarction in the rat: dose-response, temporal relations and mechanisms. J Mol Cell Cardiol (2007) 0.81
Roles of endothelial nitric oxide synthase (eNOS) and mitochondrial permeability transition pore (MPTP) in epoxyeicosatrienoic acid (EET)-induced cardioprotection against infarction in intact rat hearts. J Mol Cell Cardiol (2013) 0.81
Delayed cardioprotection is mediated via a non-peptide delta opioid agonist, SNC-121, independent of opioid receptor stimulation. Basic Res Cardiol (2003) 0.80
Eribis peptide 94 reduces infarct size in rat hearts via activation of centrally located μ opioid receptors. J Cardiovasc Pharmacol (2012) 0.80
Gadolinium decreases inflammation related to myocardial ischemia and reperfusion injury. J Inflamm (Lond) (2009) 0.80
Endogenous hydrogen sulfide insufficiency as a predictor of sexual dysfunction in aging rats. Aging Male (2012) 0.80
Factors mediating remote preconditioning of trauma in the rat heart: central role of the cytochrome p450 epoxygenase pathway in mediating infarct size reduction. J Cardiovasc Pharmacol Ther (2012) 0.79
Oltipraz-induced phase 2 enzyme response conserved in cells lacking mitochondrial DNA. Biochem Biophys Res Commun (2005) 0.79
Cardioprotective effects of nitroparacetamol and paracetamol in acute phase of myocardial infarction in experimental rats. Am J Physiol Heart Circ Physiol (2005) 0.79
Rural Oregon community perspectives: introducing community-based participatory research into a community health coalition. Prog Community Health Partnersh (2013) 0.78
Expression of neuronal nitric oxide synthase in the internal thoracic artery and saphenous vein. J Thorac Cardiovasc Surg (2006) 0.78
Flurbiprofen and HCT1026 protect mice against acute pancreatitis-associated lung injury. Shock (2005) 0.78
Attenuation of heat shock-induced cardioprotection by treatment with the opiate receptor antagonist naloxone. Am J Physiol Heart Circ Physiol (2002) 0.76
Acute and chronic cardioprotection by the enkephalin analogue, Eribis peptide 94, is mediated via activation of nitric oxide synthase and adenosine triphosphate-regulated potassium channels. Pharmacology (2012) 0.75
Could hydrogen sulfide be the next blockbuster treatment for inflammatory disease? Expert Rev Clin Pharmacol (2013) 0.75