PubRank

Janetta G Culvenor

Author PubWeight™ 31.05‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 C-terminal truncation and Parkinson's disease-associated mutations down-regulate the protein serine/threonine kinase activity of PTEN-induced kinase-1. Hum Mol Genet 2006 1.97
2 Dopamine D2 receptor knockout mice develop features of Parkinson disease. Ann Neurol 2009 1.62
3 Selective inhibition of a two-step egress of malaria parasites from the host erythrocyte. J Biol Chem 2003 1.54
4 In vitro characterization of Pittsburgh compound-B binding to Lewy bodies. J Neurosci 2007 1.52
5 Dopamine promotes alpha-synuclein aggregation into SDS-resistant soluble oligomers via a distinct folding pathway. FASEB J 2005 1.51
6 Plasma alpha-synuclein is decreased in subjects with Parkinson's disease. Exp Neurol 2006 1.23
7 Biochemical aspects of the neuroprotective mechanism of PTEN-induced kinase-1 (PINK1). J Neurochem 2008 1.18
8 Amyloid precursor protein processing and retinal pathology in mouse models of Alzheimer's disease. Graefes Arch Clin Exp Ophthalmol 2009 1.10
9 In vitro characterization of the presenilin-dependent gamma-secretase complex using a novel affinity ligand. Biochemistry 2003 1.05
10 SLC30A3 responds to glucose- and zinc variations in beta-cells and is critical for insulin production and in vivo glucose-metabolism during beta-cell stress. PLoS One 2009 0.99
11 The hypoxia imaging agent CuII(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease. J Exp Med 2012 0.96
12 Diacetylbis(N(4)-methylthiosemicarbazonato) copper(II) (CuII(atsm)) protects against peroxynitrite-induced nitrosative damage and prolongs survival in amyotrophic lateral sclerosis mouse model. J Biol Chem 2011 0.96
13 Transition-state analogue gamma-secretase inhibitors stabilize a 900 kDa presenilin/nicastrin complex. Biochemistry 2005 0.95
14 Both the p33 and p55 subunits of the Helicobacter pylori VacA toxin are targeted to mammalian mitochondria. J Mol Biol 2010 0.93
15 Platelet alpha- and gamma-synucleins in Parkinson's disease and normal control subjects. J Alzheimers Dis 2002 0.93
16 Paradoxical condensation of copper with elevated beta-amyloid in lipid rafts under cellular copper deficiency conditions: implications for Alzheimer disease. J Biol Chem 2009 0.93
17 Alpha-synuclein transgenic mice exhibit reduced anxiety-like behaviour. Exp Neurol 2008 0.89
18 In vitro gamma-secretase cleavage of the Alzheimer's amyloid precursor protein correlates to a subset of presenilin complexes and is inhibited by zinc. FEBS J 2005 0.86
19 Changes in acetylcholinesterase expression are associated with altered presenilin-1 levels. Neurobiol Aging 2011 0.84
20 Analysis of the regulatory and catalytic domains of PTEN-induced kinase-1 (PINK1). Hum Mutat 2012 0.83
21 α-Synuclein transgenic mice reveal compensatory increases in Parkinson's disease-associated proteins DJ-1 and parkin and have enhanced α-synuclein and PINK1 levels after rotenone treatment. J Mol Neurosci 2010 0.82
22 Effect of Metal Chelators on γ-Secretase Indicates That Calcium and Magnesium Ions Facilitate Cleavage of Alzheimer Amyloid Precursor Substrate. Int J Alzheimers Dis 2010 0.82
23 Nicastrin expression in mouse peripheral tissues is not co-ordinated with presenilin and is high in muscle. J Neurochem 2004 0.81
24 Analysis of LRRK2 accessory repeat domains: prediction of repeat length, number and sites of Parkinson's disease mutations. Biochem Soc Trans 2012 0.81
25 Expression of truncated presenilin 2 splice variant in Alzheimer's disease, bipolar disorder, and schizophrenia brain cortex. Brain Res Mol Brain Res 2004 0.81
26 Defining the substrate specificity determinants recognized by the active site of C-terminal Src kinase-homologous kinase (CHK) and identification of β-synuclein as a potential CHK physiological substrate. Biochemistry 2011 0.81
27 Prediction of the repeat domain structures and impact of parkinsonism-associated variations on structure and function of all functional domains of leucine-rich repeat kinase 2 (LRRK2). Hum Mutat 2014 0.80
28 Presenilin 1 interacts with acetylcholinesterase and alters its enzymatic activity and glycosylation. Mol Cell Biol 2008 0.78
29 Alternative transcripts of presenilin-1 associated with frontotemporal dementia. Neuroreport 2002 0.78
30 Allosteric networks governing regulation and catalysis of Src-family protein tyrosine kinases: implications for disease-associated kinases. Clin Exp Pharmacol Physiol 2009 0.77
31 Alternative transcripts of presenilin-1 associated with frontotemporal dementia. Neuroreport 2002 0.76
32 Selecting cells with different Alzheimer's disease gamma-secretase activity using FACS. Differential effect on presenilin exon 9 gamma- and epsilon-cleavage. Eur J Biochem 2003 0.75