PubRank

H M McClure

Author PubWeight™ 162.35‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine. Science 2001 9.09
2 Live attenuated, multiply deleted simian immunodeficiency virus causes AIDS in infant and adult macaques. Nat Med 1999 3.86
3 Isolation of a T-lymphotropic retrovirus from naturally infected sooty mangabey monkeys (Cercocebus atys). Proc Natl Acad Sci U S A 1986 3.76
4 Chimeric simian/human immunodeficiency virus that causes progressive loss of CD4+ T cells and AIDS in pig-tailed macaques. J Virol 1996 2.86
5 Effect of immunization with a vaccinia-HIV env recombinant on HIV infection of chimpanzees. Nature 1987 2.82
6 Neutralizing antibody-independent containment of immunodeficiency virus challenges by DNA priming and recombinant pox virus booster immunizations. Nat Med 1999 2.77
7 Persistent infection of chimpanzees with human T-lymphotropic virus type III/lymphadenopathy-associated virus: a potential model for acquired immunodeficiency syndrome. J Virol 1986 2.65
8 Identification and biologic characterization of an acutely lethal variant of simian immunodeficiency virus from sooty mangabeys (SIV/SMM). AIDS Res Hum Retroviruses 1989 2.50
9 Sensitive and robust one-tube real-time reverse transcriptase-polymerase chain reaction to quantify SIV RNA load: comparison of one- versus two-enzyme systems. AIDS Res Hum Retroviruses 2000 2.37
10 Brief report: infection of a laboratory worker with simian immunodeficiency virus. N Engl J Med 1994 2.32
11 Postnatal passive immunization of neonatal macaques with a triple combination of human monoclonal antibodies against oral simian-human immunodeficiency virus challenge. J Virol 2001 2.30
12 Molecularly cloned SHIV-1157ipd3N4: a highly replication- competent, mucosally transmissible R5 simian-human immunodeficiency virus encoding HIV clade C Env. J Virol 2006 1.87
13 Mycobacterium paratuberculosis infection in a colony of stumptail macaques (Macaca arctoides). J Infect Dis 1987 1.70
14 Infection of chimpanzees with lymphadenopathy-associated virus. Lancet 1984 1.67
15 Development of AIDS in a chimpanzee infected with human immunodeficiency virus type 1. J Virol 1997 1.66
16 Prevalence of natural infection with simian immunodeficiency virus and simian T-cell leukemia virus type I in a breeding colony of sooty mangabey monkeys. AIDS 1990 1.59
17 Multiple viral determinants contribute to pathogenicity of the acutely lethal simian immunodeficiency virus SIVsmmPBj variant. J Virol 1993 1.49
18 Superinfection of a chimpanzee with a second strain of human immunodeficiency virus. J Virol 1987 1.47
19 Vaginal transmission of human immunodeficiency virus (HIV) to a chimpanzee. J Infect Dis 1986 1.38
20 Pharmacokinetics of 3'-fluoro-3'-deoxythymidine and 3'-deoxy-2',3'-didehydrothymidine in rhesus monkeys. Antimicrob Agents Chemother 1990 1.38
21 Isolation from African Sykes' monkeys (Cercopithecus mitis) of a lentivirus related to human and simian immunodeficiency viruses. J Virol 1991 1.38
22 Effect of a preferred companion in modulating stress in adult female rhesus monkeys. Physiol Behav 1994 1.30
23 SIV from stump-tailed macaques: molecular characterization of a highly transmissible primate lentivirus. Virology 1992 1.29
24 Autosomal trisomy in a chimpanzee: resemblance to Down's syndrome. Science 1969 1.28
25 Humoral response to SIV/SMM infection in macaque and mangabey monkeys. J Acquir Immune Defic Syndr 1990 1.25
26 3'-Azido-2',3'-dideoxyuridine (AzddU): comparative pharmacokinetics with 3'-azido-3'-deoxythymidine (AZT) in monkeys. AIDS Res Hum Retroviruses 1990 1.24
27 Lobomycosis as a disease of the Atlantic bottle-nosed dolphin (Tursiops truncatus Montagu, 1821). Am J Trop Med Hyg 1975 1.24
28 In vitro and in vivo disposition and metabolism of 3'-deoxy-2',3'-didehydrothymidine. Antimicrob Agents Chemother 1993 1.23
29 Pharmacokinetics and metabolism of racemic 2',3'-dideoxy-5-fluoro-3'-thiacytidine in rhesus monkeys. Antimicrob Agents Chemother 1992 1.20
30 O:13a,13b, a new pathogenic serotype of Yersinia enterocolitica. J Clin Microbiol 1984 1.19
31 Perturbations of cell cycle control in T cells contribute to the different outcomes of simian immunodeficiency virus infection in rhesus macaques and sooty mangabeys. J Virol 2006 1.17
32 Emergence of cytotoxic T lymphocyte escape mutations in nonpathogenic simian immunodeficiency virus infection. Eur J Immunol 2001 1.17
33 Tumors in nonhuman primates: observations during a six-year period in the Yerkes primate center colony. Am J Phys Anthropol 1973 1.14
34 Progressive infection in a subset of HIV-1-positive chimpanzees. J Infect Dis 2000 1.14
35 Formation of a new social group of unfamiliar female rhesus monkeys affects the immune and pituitary adrenocortical systems. Brain Behav Immun 1991 1.11
36 Isolation and characterization of a neuropathogenic simian immunodeficiency virus derived from a sooty mangabey. J Virol 1998 1.11
37 Inhibition of SIV/SMM replication in vitro by CD8+ cells from SIV/SMM infected seropositive clinically asymptomatic sooty mangabeys. J Med Primatol 1990 1.10
38 Brain weight throughout the life span of the chimpanzee. J Comp Neurol 1999 1.06
39 Protection of neonatal macaques against experimental SHIV infection by human neutralizing monoclonal antibodies. Transfus Clin Biol 2001 1.03
40 Pharmacokinetics of (-)-beta-D-dioxolane guanine and prodrug (-)-beta-D-2,6-diaminopurine dioxolane in rats and monkeys. AIDS Res Hum Retroviruses 1999 1.03
41 Polyclonal B-cell activation reveals antibodies against human immunodeficiency virus type 1 (HIV-1) in HIV-1-seronegative individuals. Proc Natl Acad Sci U S A 1990 1.01
42 Arcobacter (Campylobacter) butzleri-associated diarrheal illness in a nonhuman primate population. Infect Immun 1993 1.00
43 Pharmacokinetics of 3'-azido-3'-deoxythymidine and its catabolites and interactions with probenecid in rhesus monkeys. Antimicrob Agents Chemother 1991 1.00
44 Oral transmission of primate lentiviruses. J Infect Dis 1999 0.99
45 The proteins of lymphocyte- and macrophage-tropic strains of simian immunodeficiency virus are processed differently in macrophages. Virology 1995 0.99
46 Oral immunization of macaques with attenuated vaccine virus induces protection against vaginally transmitted AIDS. J Virol 1998 0.99
47 Consequences of opiate-dependency in a monkey model of AIDS. Adv Exp Med Biol 1993 0.98
48 Effect of companions in modulating stress associated with new group formation in juvenile rhesus macaques. Physiol Behav 1996 0.97
49 Ultrastructure of atypical (teratoid) sporogonial stages of Enterocytozoon bieneusi (Microsporidia) in naturally infected rhesus monkeys (Macacca mulatta). Arch Pathol Lab Med 1998 0.96
50 HIV infection of chimpanzees as a model for testing chemotherapeutics. Intervirology 1989 0.96
51 Passive immunization against oral AIDS virus transmission: an approach to prevent mother-to-infant HIV-1 transmission? J Med Primatol 2001 0.95
52 Parallel evolution of CCR5-null phenotypes in humans and in a natural host of simian immunodeficiency virus. Curr Biol 1998 0.95
53 Prolonged CD4+ lymphocytopenia and thrombocytopenia in a chimpanzee persistently infected with human immunodeficiency virus type 1. J Infect Dis 1991 0.95
54 Rapid CD4(+) T-cell loss induced by human immunodeficiency virus type 1(NC) in uninfected and previously infected chimpanzees. J Virol 2001 0.94
55 Nonhuman primate models for human disease. Adv Vet Sci Comp Med 1984 0.94
56 Molecular diversity of SIVsmm/PBj and a cognate variant, SIVsmm/PGg. J Med Primatol 1991 0.94
57 Sequential immunization of macaques with two differentially attenuated vaccines induced long-term virus-specific immune responses and conferred protection against AIDS caused by heterologous simian human immunodeficiency Virus (SHIV(89.6)P). Virology 2001 0.94
58 SIVsmm infection of macaque and mangabey monkeys: correlation between in vivo and in vitro properties of different isolates. Dev Biol Stand 1990 0.93
59 Gastrointestinal neoplasms in nonhuman primates: a review and report of eleven new cases. Vet Pathol Suppl 1982 0.92
60 Viral genetic determinants in SIVsmmPBj pathogenesis. J Med Primatol 1994 0.91
61 Natural genital herpesvirus hominis infection in chimpanzees (Pan troglodytes and Pan paniscus). Lab Anim Sci 1980 0.90
62 DNA prime/protein boost vaccine strategy in neonatal macaques against simian human immunodeficiency virus. J Med Primatol 2002 0.90
63 Antiretroviral activity, biochemistry, and pharmacokinetics of 3'-azido-2',3'-dideoxy-5-methylcytidine. Ann N Y Acad Sci 1990 0.90
64 Experimental leprosy in monkeys. I. Sooty mangabey monkeys: transmission, susceptibility, clinical and pathological findings. Lepr Rev 1995 0.90
65 Social separation and reunion affects immune system in juvenile rhesus monkeys. Physiol Behav 1992 0.89
66 Chronic fatal disease in gorillas seropositive for simian T-lymphotropic virus I antibodies. Cancer Lett 1987 0.88
67 CD34+ and CFU-GM progenitors are significantly decreased in SIVsmm9 infected rhesus macaques with minimal evidence of direct viral infection by polymerase chain reaction. Am J Hematol 1993 0.88
68 Chronic immune stimulation accelerates SIV-induced disease progression. J Med Primatol 2001 0.88
69 The tyrosine-17 residue of Nef in SIVsmmPBj14 is required for acute pathogenesis and contributes to replication in macrophages. Virology 1998 0.88
70 Disseminated endometriosis in a Rhesus monkey (Macaca mulatta). Histogenesis and possible relationship to irradiation exposure 1,2. J Med Assoc Ga 1971 0.87
71 Natural Herpesvirus hominis infection of tree shrews (Tupaia glis). Lab Anim Sci 1972 0.87
72 Postinoculation PMPA treatment, but not preinoculation immunomodulatory therapy, protects against development of acute disease induced by the unique simian immunodeficiency virus SIVsmmPBj. J Virol 1999 0.87
73 Transmission of HCV to a chimpanzee using virus particles produced in an RNA-transfected HepG2 cell culture. J Med Virol 2001 0.87
74 The origin and development of the upper lateral incisor and premaxilla in normal and cleft lip/palate monkeys induced with cyclophosphamide. Cleft Palate Craniofac J 2000 0.86
75 Heterologous neutralizing antibody induction in a simian-human immunodeficiency virus primate model: lack of original antigenic sin. J Infect Dis 2001 0.86
76 Requirements for simian immunodeficiency virus antigen-specific in vitro proliferation of T cells from infected rhesus macaques and sooty mangabeys. AIDS 1990 0.86
77 Pathogenesis and immunological aspects of experimental histoplasmosis in cynomolgus monkeys (Macaca fascicularis). Infect Immun 1972 0.86
78 Detection of occult simian immunodeficiency virus SIVsmm infection in asymptomatic seronegative nonhuman primates and evidence for variation in SIV gag sequence between in vivo- and in vitro-propagated virus. J Virol 1991 0.85
79 Phenotypic and functional differences in NK and LAK cells in the peripheral blood of sooty mangabeys and rhesus macaques. Cell Immunol 1989 0.85
80 Erythroleukemia in two infant chimpanzees fed milk from cows naturally infected with the bovine C-type virus. Cancer Res 1974 0.84
81 Pharmacokinetics of the antiviral agent beta-D-2',3'-didehydro-2',3'-dideoxy-5-fluorocytidine in rhesus monkeys. Antimicrob Agents Chemother 1999 0.84
82 Multi-envelope HIV vaccine safety and immunogenicity in small animals and chimpanzees. Immunol Res 2000 0.84
83 Comparison of SIV/SMM replication in CD4+ T cell and monocyte/macrophage cultures from rhesus macaques and sooty mangabeys. J Med Primatol 1990 0.83
84 Pseudotuberculosis in nonhuman primates: infection with organisms of the Yersinia enterocolitica group. Lab Anim Sci 1971 0.83
85 Immunogenicity and safety of Mycobacterium tuberculosis culture filtrate proteins in non-human primates. Clin Exp Immunol 2000 0.83
86 Perinatal listeric septicemia in a Celebese black ape. J Am Vet Med Assoc 1975 0.83
87 Alkaptonuria in an orangutan (Pongo pygmaeus). Am J Phys Anthropol 1973 0.83
88 Chesson strain Plasmodium vivax in Saimiri sciureus boliviensis monkeys. J Parasitol 1987 0.83
89 Ovarian tumors and related lesions in aged chimpanzees. Vet Pathol 1977 0.83
90 Sporozoite-induced infections of the Salvador I strain of Plasmodium vivax in Saimiri sciureus boliviensis monkeys. J Parasitol 1988 0.82
91 Endometrial adenocarcinoma, endometriosis, and pyometra in a rhesus monkey. J Am Vet Med Assoc 1972 0.82
92 Hematologic and blood chemistry data for the gorilla (Gorilla gorilla). Folia Primatol (Basel) 1972 0.82
93 High-performance liquid chromatographic determination of (-)-beta-D-2-aminopurine dioxolane and (-)-beta-D-2-amino-6-chloropurine dioxolane, and their metabolite (-)-beta-D-dioxolane guanine in monkey serum, urine and cerebrospinal fluid. J Chromatogr B Biomed Sci Appl 1997 0.82
94 Pharmacokinetics and metabolism of 3'-azido-2',3'-dideoxy-5-methylcytidine in rhesus monkeys. Drug Metab Dispos 1993 0.82
95 Viral diseases noted in the Yerkes Primate Center colony. Lab Anim Sci 1971 0.81
96 Pulmonary pneumocystosis in nonhuman primates. Arch Pathol Lab Med 1976 0.81
97 Accidental infection of laboratory-reared Macaca mulatta with Trypanosoma cruzi. Lab Anim Sci 1974 0.81
98 Treatment of thrombocytopenia in chimpanzees infected with human immunodeficiency virus by pegylated recombinant human megakaryocyte growth and development factor. Blood 1998 0.81
99 Clinical and pathologic findings in infant rhesus macaques infected with SIVsmm by maternal transmission. J Med Primatol 1993 0.81
100 Evidence for a lentiviral etiology in an epizootic of immune deficiency and lymphoma in stump-tailed macaques (Macaca arctoides). J Med Primatol 1992 0.81
101 DNA priming and recombinant pox virus boosters for an AIDS vaccine. Dev Biol (Basel) 2000 0.81
102 Infection of mosquitoes with Plasmodium vivax from chimpanzees using membrane feeding. Am J Trop Med Hyg 1986 0.81
103 The disruption of macaque CD4+ T-cell repertoires during the early simian immunodeficiency virus infection. J Med Primatol 1999 0.81
104 Necrotizing pancreatitis due to simian adenovirus type 31 in a rhesus monkey. Arch Pathol Lab Med 1978 0.81
105 A survey of pancreatic lesions in nonhuman primates. Vet Pathol Suppl 1982 0.80
106 Fluorescence of the trisomic chimpanzee chromosomes. J Med Primatol 1974 0.80
107 Effect of recombinant human interleukin-6 (rhIL-6) and rhIL-3 on hematopoietic regeneration as demonstrated in a nonhuman primate chemotherapy model. Blood 1994 0.80
108 Active and passive immunization against HIV type 1 infection in chimpanzees. AIDS Res Hum Retroviruses 1998 0.80
109 Multifactorial etiology of anemia in SIV-infected rhesus macaques: decreased BFU-E formation, serologic evidence of autoimmune hemolysis, and an exuberant erythropoietin response. J Med Primatol 1993 0.80
110 Deletion of the nef gene abrogates the ability of SIV smmPBj to induce acutely lethal disease in pigtail macaques. AIDS Res Hum Retroviruses 1996 0.80
111 Identification of SIV/SMM viral proteins that induce T cell response in experimentally infected rhesus macaques and naturally infected sooty mangabeys by the cellular western blot assay. J Med Primatol 1990 0.80
112 Gastrointestinal neoplasms in nonhuman primates: a review and report of eleven new cases. Vet Pathol Suppl 1982 0.80
113 Malignant uterine mesotheliomas in squirrel monkeys following diethylstilbestrol administration. Lab Anim Sci 1973 0.80
114 Characterization of a novel baboon virus closely resembling human T-cell leukemia virus. Virology 1996 0.80
115 Pharmacokinetics of beta-L-2',3'-dideoxy-5-fluorocytidine in rhesus monkeys. Antimicrob Agents Chemother 1999 0.80
116 Transmission of retroviral infection by transfusion of seronegative blood in nonhuman primates. J Infect Dis 1991 0.80
117 Enteropathogenic Escherichia coli infection in anthropoid apes. J Am Vet Med Assoc 1972 0.79
118 Pulmonary nocardiosis in an orangutan. J Am Vet Med Assoc 1976 0.79
119 Prolonged dominance of clonally restricted CD4(+) T cells in macaques infected with simian immunodeficiency viruses. J Virol 2000 0.79
120 Persistent infection of rhesus macaques by the rev-independent Nef(-) simian immunodeficiency virus SIVmac239: replication kinetics and genomic stability. J Virol 1999 0.79
121 In utero lip repair in the rhesus monkey: an update. Plast Reconstr Surg 1987 0.79
122 Spermatogenesis and hormone levels in rhesus macaques inoculated with simian immunodeficiency virus. J Med Primatol 1993 0.79
123 Blastocystis hominis in a pig-tailed macaque: a potential enteric pathogen for nonhuman primates. Lab Anim Sci 1980 0.79
124 Plasmodium vivax infections in chimpanzees for sporozoite challenge studies in monkeys. Am J Trop Med Hyg 1996 0.79
125 Serological evidence of alpha herpesvirus infection in sooty mangabeys. J Med Primatol 2002 0.79
126 Ectopic pregnancy in a squirrel monkey. J Am Vet Med Assoc 1975 0.79
127 Comparison of immunogenicity of fresh and stored blood. A study in rhesus monkeys. Transplantation 1982 0.79
128 Effects of morphine on T-cell recirculation in rhesus monkeys. Adv Exp Med Biol 2001 0.79
129 Chemotherapy-induced hemolytic uremic syndrome: description of a potential animal model. J Med Primatol 1995 0.78
130 Pathogenesis of lymphocyte-tropic and macrophage-tropic SIVmac infection in the brain. J Neurovirol 1995 0.78
131 Primary Herpesvirus simiae (B-virus) infection in infant macaques. Lab Anim Sci 1994 0.78
132 Infection of chimpanzees with the Uganda I/CDC strain of Plasmodium malariae. Am J Trop Med Hyg 1990 0.78
133 Infection of chimpanzees with Nigerian I/CDC strain of Plasmodium ovale. Am J Trop Med Hyg 1987 0.78
134 Chromobacterium violaceum infection in a nonhuman primate (Macaca assamensis). Lab Anim Sci 1976 0.78
135 The Nigerian I/CDC strain of Plasmodium ovale in chimpanzees. J Parasitol 1996 0.77
136 Simian immunodeficiency virus SIVsmmPBj 1.9 induces multinucleated giant cell formation in human peripheral blood monocytes. AIDS Res Hum Retroviruses 1994 0.77
137 Removal from natal social group to peer housing affects cortisol levels and absolute numbers of T cell subsets in juvenile rhesus monkeys. Brain Behav Immun 1992 0.77
138 Disseminated herpesvirus infection in a rhesus monkey (Macaca mulatta). J Med Primatol 1973 0.77
139 Behavioral and physiological response of juvenile sooty mangabeys to reunion with their mothers following a year's absence. Dev Psychobiol 1992 0.76
140 Nonspecific immunosuppressive effect of platelet transfusion in rhesus monkeys. Transplantation 1987 0.76
141 Induction of long-term protective effects against heterologous challenge in SIVhu-infected macaques. Virology 2000 0.76
142 Hematologic and blood chemistry data for the orangutan (Pongo pygmaeus). Folia Primatol (Basel) 1972 0.76
143 Severe autoimmune hemolytic anemia in SIVsmm9-infected Macaca mulatta. J Med Primatol 1991 0.76
144 Neonatal treatment with luteinizing hormone-releasing hormone analogs alters peripheral lymphocyte subsets and cellular and humorally mediated immune responses in juvenile and adult male monkeys. J Clin Endocrinol Metab 1994 0.76
145 Sertoli-Leydig cell tumor in a chimpanzee. Lab Anim Sci 1976 0.75
146 Effects of 5-benzylacyclouridine, an inhibitor of uridine phosphorylase, on the pharmacokinetics of uridine in rhesus monkeys: implications for chemotherapy. Cancer Chemother Pharmacol 1995 0.75
147 Strongyloidosis in two infant orangutans. J Am Vet Med Assoc 1973 0.75
148 Genetic markers of immunoglobulins in the two orangutan subspecies and their hybrids. Folia Primatol (Basel) 1984 0.75
149 Diagnostic exercise. Yersiniosis. Lab Anim Sci 1980 0.75
150 The chimpanzee as an animal model for investigating alcoholism. Science 1972 0.75
151 T-lymphocyte levels in the peripheral blood of gamma irradiated rhesus monkeys. Strahlentherapie 1975 0.75
152 Antibody to human MHC class I inhibits SIVsmmPBj1.9-induced proliferation of pigtailed macaque lymphocytes. Exp Clin Immunogenet 1997 0.75
153 Comparison of hemagglutination inhibition pregnancy tests in the chimpanzee and the orangutan. Lab Anim Sci 1976 0.75
154 Lymphocytotoxic antibodies induced by fresh blood, stored blood, and platelets in rhesus monkeys. Transplant Proc 1982 0.75
155 Adenoviral pancreatitis in rhesus monkeys: current knowledge. Vet Pathol Suppl 1982 0.75
156 Immunological unresponsiveness induced by platelet transfusion in rhesus monkeys. Transplantation 1983 0.75
157 Guidelines for the prevention of simian immunodeficiency virus infection in laboratory workers and animal handlers. J Med Primatol 1989 0.75
158 Lack of transmission of human immunodeficiency virus from infected to uninfected chimpanzees. J Med Primatol 1987 0.75
159 High-performance liquid chromatographic determination of (-)-beta-D-2,6-diaminopurine dioxolane and its metabolite, dioxolane guanosine, using ultraviolet and on-line radiochemical detection. J Chromatogr B Biomed Appl 1995 0.75
160 Adenoviral pancreatitis in rhesus monkeys: current knowledge. Vet Pathol Suppl 1982 0.75
161 Presence of SIV antibodies in the sera of infants born to SIV-seronegative monkeys. J Acquir Immune Defic Syndr 1991 0.75
162 Cholangiocarcinoma in a Margay (Felis wiedii). Vet Pathol 1977 0.75
163 Preventive medicine in anthropoids: parasite control. Lab Anim Sci 1973 0.75
164 Studies on the use of nonhuman primates to determine the DR status of the human hematopoietic stem cell. Exp Hematol 1985 0.75
165 Encephalomyelitis due to a Sarcocystis neurona-like protozoan in a rhesus monkey (Macaca mulatta) infected with simian immunodeficiency virus. Am J Trop Med Hyg 1994 0.75
166 Studies of an improved rhesus hematopoietic progenitor cell assay. Exp Hematol 1992 0.75
167 Lymphocytotoxic donor-specific response to fresh and stored blood. An experiment in immunosuppressed rhesus monkies (brief communication). Int Urol Nephrol 1984 0.75
168 Acute disseminated fatal toxoplasmosis in a squirrel monkey. J Am Vet Med Assoc 1982 0.75
169 Disseminated oesophagostomiasis in the rhesus monkey. J Am Vet Med Assoc 1975 0.75
170 Nonenteric Shigella infections in nonhuman primates. J Am Vet Med Assoc 1976 0.75
171 In vitro and in vivo metabolism and pharmacokinetics of bis [(t-butyl)-S-acyl-2-thioethyl]-beta-L-2',3'-dideoxy-5-fluorocytidine monophosphate. Nucleosides Nucleotides Nucleic Acids 2000 0.75
172 Effects of recombinant human granulocyte-macrophage colony-stimulating factor on platelet survival and activation using a nonhuman primate model. Exp Hematol 1993 0.75