Safety and efficacy of recombinant activated factor VII: a randomized placebo-controlled trial in the setting of bleeding after cardiac surgery.

Off-label use of recombinant factor VIIa in U.S. hospitals: analysis of hospital records. Ann Intern Med (2011) 2.87

Systematic review: benefits and harms of in-hospital use of recombinant factor VIIa for off-label indications. Ann Intern Med (2011) 2.68

Recombinant factor VII is associated with worse survival in complex cardiac surgical patients. Ann Thorac Surg (2014) 2.09

Recommendations for the implementation of a Patient Blood Management programme. Application to elective major orthopaedic surgery in adults. Blood Transfus (2015) 1.46

Spanish Consensus Statement on alternatives to allogeneic blood transfusion: the 2013 update of the "Seville Document". Blood Transfus (2013) 1.23

Off-label recombinant factor VIIa use and thrombosis in children: a multi-center cohort study. J Pediatr (2010) 1.15

Predictors of massive transfusion with thoracic aortic procedures involving deep hypothermic circulatory arrest. J Thorac Cardiovasc Surg (2010) 1.09

Reduction of Fresh Frozen Plasma Requirements by Perioperative Point-of-Care Coagulation Management with Early Calculated Goal-Directed Therapy. Transfus Med Hemother (2012) 1.08

Intraoperative use of low-dose recombinant activated factor VII during thoracic aortic operations. Ann Thorac Surg (2012) 1.08

Use of recombinant factor VIIa for the prevention and treatment of bleeding in patients without hemophilia: a systematic review and meta-analysis. CMAJ (2010) 0.98

The evidence for the use of recombinant factor VIIa in massive bleeding: revision of the transfusion policy framework. Transfus Med (2012) 0.86

Randomized, double-blinded, placebo-controlled trial of fibrinogen concentrate supplementation after complex cardiac surgery. J Am Heart Assoc (2015) 0.85

Use of Activated Recombinant Factor VII in Severe Bleeding - Evidence for Efficacy and Safety in Trauma, Postpartum Hemorrhage, Cardiac Surgery, and Gastrointestinal Bleeding. Transfus Med Hemother (2012) 0.84

Association of coagulation-related and inflammation-related genes and factor VIIc levels with stroke: the Cardiovascular Health Study. J Thromb Haemost (2011) 0.84

The Effect of Intravenous Administration of Active Recombinant Factor VII on Postoperative Bleeding in Cardiac Valve Reoperations; A Randomized Clinical Trial. Anesth Pain Med (2015) 0.83

Prothrombin complex concentrate mitigates diffuse bleeding after cardiopulmonary bypass in a porcine model. Br J Anaesth (2010) 0.83

Recombinant human factor VIIa for alveolar hemorrhage following allogeneic stem cell transplantation. Biol Blood Marrow Transplant (2014) 0.82

Rational Use of Recombinant Factor VIIa in Clinical Practice. Indian J Hematol Blood Transfus (2013) 0.80

The Australian and New Zealand Haemostasis Registry: ten years of data on off-licence use of recombinant activated factor VII. Blood Transfus (2014) 0.80

Interventional Algorithms for the Control of Coagulopathic Bleeding in Surgical, Trauma, and Postpartum Settings: Recommendations From the Share Network Group. Clin Appl Thromb Hemost (2014) 0.80

Major themes for 2009 in cardiothoracic and vascular anesthesia. HSR Proc Intensive Care Cardiovasc Anesth (2010) 0.78

Recombinant Activated Factor VII Significantly Reduces Transfusion Requirements in Cardiothoracic Surgery. Drugs R D (2015) 0.78

The role of recombinant activated factor VII in cardiac surgery. HSR Proc Intensive Care Cardiovasc Anesth (2009) 0.77

Letter by Al-Ruzzeh and Navia regarding article, "Safety and efficacy of recombinant activated factor VII: a randomized placebo-controlled trial in the setting of bleeding after cardiac surgery". Circulation (2010) 0.77

Emergency cardiac surgery in patients with acute coronary syndromes: a review of the evidence and perioperative implications of medical and mechanical therapeutics. Anesth Analg (2011) 0.76

Salvage use of activated recombinant factor VII in the management of refractory bleeding following cardiac surgery. J Blood Med (2011) 0.76

Combination use of platelets and recombinant activated factor VII for increased hemostasis during acute type a dissection operations. J Cardiothorac Surg (2014) 0.76

Perioperative management of the bleeding patient. Br J Anaesth (2016) 0.75

Effect of 22q11.2 deletion on bleeding and transfusion utilization in children with congenital heart disease undergoing cardiac surgery. Pediatr Res (2015) 0.75

Prothrombin Complex Concentrates for Bleeding in the Perioperative Setting. Anesth Analg (2016) 0.75

Recombinant activated factor VII for uncontrolled bleeding postcardiac surgery. J Saudi Heart Assoc (2016) 0.75

Impact on postoperative bleeding and cost of recombinant activated factor VII in patients undergoing heart transplantation. Ann Card Anaesth (2016) 0.75

Comparison of low- and high-dose recombinant activated factor VII for postcardiac surgical bleeding. Indian J Crit Care Med (2016) 0.75

Incidence of Venous Thromboembolism and Benefits and Risks of Thromboprophylaxis After Cardiac Surgery: A Systematic Review and Meta-Analysis. J Am Heart Assoc (2015) 0.75

Perioperative management and monitoring of antiplatelet agents: a focused review on aspirin and P2Y12 inhibitors. Korean J Anesthesiol (2017) 0.75

Mortality associated with aprotinin during 5 years following coronary artery bypass graft surgery. JAMA (2007) 6.04

Referral to an extracorporeal membrane oxygenation center and mortality among patients with severe 2009 influenza A(H1N1). JAMA (2011) 4.24

Position paper for the organization of extracorporeal membrane oxygenation programs for acute respiratory failure in adult patients. Am J Respir Crit Care Med (2014) 2.78

Mechanical methods of reducing blood transfusion in cardiac surgery: randomised controlled trial. BMJ (2002) 2.57

Is blood cardioplegia superior to crystalloid cardioplegia? Interact Cardiovasc Thorac Surg (2008) 2.22

Effect of increasing pump speed during exercise on peak oxygen uptake in heart failure patients supported with a continuous-flow left ventricular assist device. A double-blind randomized study. Eur J Heart Fail (2014) 1.99

Increased chest tube drainage is independently associated with adverse outcome after cardiac surgery. J Cardiothorac Vasc Anesth (2011) 1.74

Costs of excessive postoperative hemorrhage in cardiac surgery. J Thorac Cardiovasc Surg (2009) 1.69

A randomized controlled trial of cell salvage in routine cardiac surgery. Anesth Analg (2008) 1.62

Delayed re-exploration for bleeding after coronary artery bypass surgery results in adverse outcomes. Eur J Cardiothorac Surg (2007) 1.62

Successful extracorporeal membrane oxygenation support after pulmonary thromboendarterectomy. Ann Thorac Surg (2008) 1.61

Significant blood resistance to nitric oxide transfer in the lung. J Appl Physiol (1985) (2010) 1.57

Pre-operative high sensitive C-reactive protein predicts cardiovascular events after coronary artery bypass grafting surgery: a prospective observational study. Ann Card Anaesth (2009) 1.55

Prolonged stay in intensive care unit is a powerful predictor of adverse outcomes after cardiac operations. Ann Thorac Surg (2012) 1.53

Validity and reliability of the DDS for severity of delirium in the ICU. Neurocrit Care (2005) 1.52

Agreement of central venous saturation and mixed venous saturation in cardiac surgery patients. Intensive Care Med (2007) 1.51

Comparison of uncalibrated arterial waveform analysis in cardiac surgery patients with thermodilution cardiac output measurements. Crit Care (2006) 1.51

Contemporary fluid management in cardiac anesthesia. J Cardiothorac Vasc Anesth (2010) 1.46

Risk of stroke after coronary artery bypass grafting: effect of age and comorbidities. Stroke (2011) 1.43

Endovascular carotid artery stenting and early coronary artery bypass grafting for asymptomatic carotid artery stenosis: long-term outcomes and neurologic events. Catheter Cardiovasc Interv (2009) 1.42

[The Mechanical Heart--HeartMate 1--Danish results]. Ugeskr Laeger (2007) 1.40

Design and rationale for RE-VERSE AD: A phase 3 study of idarucizumab, a specific reversal agent for dabigatran. Thromb Haemost (2015) 1.36

Pulse contour analysis after normothermic cardiopulmonary bypass in cardiac surgery patients. Crit Care (2005) 1.21

Caudwell Xtreme Everest: a field study of human adaptation to hypoxia. Crit Care (2007) 1.21

The clinical application of mobile technology to disaster medicine. Prehosp Disaster Med (2012) 1.16

Service redesign. Fitter, faster: improved pathways speed up recovery. Health Serv J (2011) 1.10

Consensus views on implementation and measurement of enhanced recovery after surgery in England: Delphi study. BMJ Open (2012) 1.08

ESA guidelines on the management of severe perioperative bleeding: comments on behalf of the Subcommittee on Transfusion and Haemostasis of the European Association of Cardiothoracic Anaesthesiologists. Eur J Anaesthesiol (2014) 1.07

Anaesthesia for noncardiac surgery in the heart transplant recipient. Curr Opin Anaesthesiol (2009) 1.04

Electronic patient record use during ward rounds: a qualitative study of interaction between medical staff. Crit Care (2008) 1.02

Current use of intraosseous infusion in Danish emergency departments: a cross-sectional study. Scand J Trauma Resusc Emerg Med (2010) 1.01

Pulmonary endarterectomy is possible and effective without the use of complete circulatory arrest--the UK experience in over 150 patients. Eur J Cardiothorac Surg (2008) 1.01

Preoperative oral carbohydrate administration to ASA III-IV patients undergoing elective cardiac surgery. Anesth Analg (2006) 1.01

Mortality associated with administration of high-dose tranexamic acid and aprotinin in primary open-heart procedures: a retrospective analysis. Crit Care (2010) 0.96

Can a membrane oxygenator be a model for lung NO and CO transfer? J Appl Physiol (1985) (2006) 0.95

Early outcome after surgery for active native and prosthetic aortic valve endocarditis. J Heart Valve Dis (2008) 0.94

What's new in ECMO: scoring the bad indications. Intensive Care Med (2014) 0.94

A moribund athlete. Lancet (2012) 0.93

Role of Reactive Oxygen Species in Tumor Necrosis Factor-alpha Induced Endothelial Dysfunction. Curr Hypertens Rev (2008) 0.93

Is bicaval orthotopic heart transplantation superior to the biatrial technique? Interact Cardiovasc Thorac Surg (2009) 0.92

Dentoalveolar injury related to general anaesthesia: a 14 years review and a statement from the surgical point of view based on a retrospective analysis of the documentation of a university hospital. Dent Traumatol (2011) 0.92

Implementing the International Liaison Committee on Resuscitation guidelines on hypothermia after cardiac arrest. The German experience: still a long way to go? Crit Care (2006) 0.92

Increased interleukin-6 after cardiac surgery predicts infection. Anesth Analg (2006) 0.92

PREPARE: the prevalence of perioperative anaemia and need for patient blood management in elective orthopaedic surgery: a multicentre, observational study. Eur J Anaesthesiol (2015) 0.92

Prediction of volume response under open-chest conditions during coronary artery bypass surgery. Crit Care (2007) 0.90

Related transcriptional enhancer factor 1 increases endothelial-dependent microvascular relaxation and proliferation. J Vasc Res (2012) 0.89

Allogenic blood transfusion does not predispose to infection after cardiac surgery. Ann Thorac Surg (2004) 0.88

Evaluation of immunohematologic routine methods using the new erythrocyte-magnetized technology on the QWALYS 2 system. Transfusion (2009) 0.88

Validation of a hospital-laboratory workstation for immunohematologic methods. Transfusion (2009) 0.88

Efficacy and safety of recombinant factor XIII on reducing blood transfusions in cardiac surgery: a randomized, placebo-controlled, multicenter clinical trial. J Thorac Cardiovasc Surg (2013) 0.87

Altered immune parameters in chronic alcoholic patients at the onset of infection and of septic shock. Crit Care (2004) 0.87

High permeability haemofiltration improves peripheral blood mononuclear cell proliferation in septic patients with acute renal failure. Nephrol Dial Transplant (2003) 0.87

A european, multicenter, observational study to assess the value of gastric-to-end tidal PCO2 difference in predicting postoperative complications. Anesth Analg (2004) 0.87

Initial impact of drug-eluting stents on coronary artery bypass graft surgery. Ann Thorac Surg (2006) 0.86

Patient blood management during cardiac surgery: do we have enough evidence for clinical practice? J Thorac Cardiovasc Surg (2011) 0.86

Lithium-induced nephrogenic diabetes insipidus after coronary artery bypass. Ann Thorac Surg (2007) 0.85

Impact of hyperglycemia on perioperative mortality after coronary artery bypass graft surgery. J Thorac Cardiovasc Surg (2011) 0.85

Increased interleukin-10 and cortisol in long-term alcoholics after cardiopulmonary bypass: a hint to the increased postoperative infection rate? Alcohol Clin Exp Res (2005) 0.84

Life-threatening right ventricular failure in pulmonary hypertension: RVAD or ECMO? J Heart Lung Transplant (2008) 0.84

Optimizing intraoperative fluid therapy. Curr Opin Anaesthesiol (2003) 0.84

The significant blood resistance to lung nitric oxide transfer lies within the red cell. J Appl Physiol (1985) (2013) 0.83

Perioperative melatonin secretion in patients undergoing coronary artery bypass grafting. Anesth Analg (2002) 0.83

Perioperative indocyanine green clearance is predictive for prolonged intensive care unit stay after coronary artery bypass grafting--an observational study. Crit Care (2009) 0.83

Direct complications of the Avalon bicaval dual-lumen cannula in respiratory extracorporeal membrane oxygenation (ECMO): Single-center experience. Int J Artif Organs (2014) 0.83

The influence of seasons and lunar cycle on hospital outcomes following ascending aortic dissection repair. Interact Cardiovasc Thorac Surg (2013) 0.83

Does body mass index (BMI) affect cost in cardiac surgery? 'A pound (pound) for pound (lb) analysis'. Interact Cardiovasc Thorac Surg (2006) 0.81

Intermittent high permeability hemofiltration in septic patients with acute renal failure. Intensive Care Med (2003) 0.81

Central and peripheral blood flow during exercise with a continuous-flow left ventricular assist device: constant versus increasing pump speed: a pilot study. Circ Heart Fail (2011) 0.81

Constrictive pericarditis in a contemporary Danish cohort: aetiology and outcome. Scand Cardiovasc J (2015) 0.81

Protocols, physiology, and trials of hydroxyethyl starch. N Engl J Med (2012) 0.81

[Therapy of trauma-induced coagulopathy - what is the evidence?]. Anasthesiol Intensivmed Notfallmed Schmerzther (2012) 0.80

Driveline infections in patients supported with a HeartMate II: incidence, aetiology and outcome. Scand Cardiovasc J (2011) 0.79

Recombinant factor VIIa: a universal haemostatic agent? Ann Card Anaesth (2006) 0.79

Minimally invasive aortic valve replacement: late conversion to full sternotomy doubles operative time. Tex Heart Inst J (2009) 0.79

Cytokine phenotype, genotype, and renal outcomes at cardiac surgery. Cytokine (2012) 0.79

Repletion of factor XIII following cardiopulmonary bypass using a recombinant A-subunit homodimer. A preliminary report. Thromb Haemost (2009) 0.79

Reducing blood transfusion. BMJ 's cover and headline exaggerated importance of study's findings. BMJ (2002) 0.79

Atrial Na,K-ATPase increase and potassium dysregulation accentuate the risk of postoperative atrial fibrillation. Cardiology (2009) 0.78

Brief hospitalizations of elderly patients: a retrospective, observational study. Scand J Trauma Resusc Emerg Med (2014) 0.78

Increased gastric-end tidal P(CO2) gap during exercise at high altitude measured by gastric tonometry. High Alt Med Biol (2007) 0.78

Lyophilised plasma: evaluation of clotting factor activity over 6 days after reconstitution for transfusion. J Clin Pathol (2010) 0.78

The Nordic aortic valve intervention (NOTION) trial comparing transcatheter versus surgical valve implantation: study protocol for a randomised controlled trial. Trials (2013) 0.78

A lipopolysaccharide adsorber in adult cardiopulmonary bypass: a single centre randomised controlled pilot trial. Interact Cardiovasc Thorac Surg (2010) 0.77

Intermittent hirudin versus continuous heparin for anticoagulation in continuous renal replacement therapy. Ren Fail (2004) 0.77

[Percutaneous aortic valve replacement - initial experience and results]. Ugeskr Laeger (2009) 0.77

The many flavors of IGF-I. J Appl Physiol (1985) (2006) 0.77

Electroencephalographic mapping during routine clinical practice: cortical arousal during tracheal intubation? Anesth Analg (2006) 0.77

APT070 inhibits complement activation during in vitro cardiopulmonary bypass. Eur J Cardiothorac Surg (2006) 0.77

Multimodal analgesia versus traditional opiate based analgesia after cardiac surgery, a randomized controlled trial. J Cardiothorac Surg (2014) 0.77

Levosimendan may improve survival in patients requiring mechanical assist devices for post-cardiotomy heart failure. Crit Care (2006) 0.77

[Fluid therapy--pathophysiological principles as well as intra- and perioperative monitoring]. Anasthesiol Intensivmed Notfallmed Schmerzther (2006) 0.77

'You can't just hit a button': an ethnographic study of strategies to repurpose data from advanced clinical information systems for clinical process improvement. BMC Med (2013) 0.77

Protracted bleeding after hirudin anticoagulation for cardiac surgery in a patient with HIT II and chronic renal failure. Artif Organs (2005) 0.76

An operational research approach to identify cardiac surgery patients at risk of severe post-operative bleeding. Health Care Manag Sci (2011) 0.76

Potential cost saving of Epoetin alfa in elective hip or knee surgery due to reduction in blood transfusions and their side effects: a discrete-event simulation model. PLoS One (2013) 0.76

Clonidine attenuated early proinflammatory response in T-cell subsets after cardiac surgery. Anesth Analg (2006) 0.76

Biological efficacy of low against medium dose aspirin regimen after coronary surgery: analysis of platelet function. Thromb Haemost (2006) 0.76

Recombinant factor VIIa after aortic valve replacement in a patient with osteogenesis imperfecta. Ann Thorac Surg (2002) 0.76

Safety and efficacy of aprotinin and tranexamic acid in pulmonary endarterectomy surgery with hypothermia: review of 200 patients. Ann Thorac Surg (2010) 0.76

Recombinant factor VIIa for excessive bleeding after thrombectomy prior to kidney transplantation. Transplantation (2004) 0.76