International guidelines for the diagnosis and management of hereditary haemorrhagic telangiectasia.

PubWeight™: 3.89‹?› | Rank: Top 1%

🔗 View Article (PMID 19553198)

Published in J Med Genet on June 23, 2009

Authors

M E Faughnan1, V A Palda, G Garcia-Tsao, U W Geisthoff, J McDonald, D D Proctor, J Spears, D H Brown, E Buscarini, M S Chesnutt, V Cottin, A Ganguly, J R Gossage, A E Guttmacher, R H Hyland, S J Kennedy, J Korzenik, J J Mager, A P Ozanne, J F Piccirillo, D Picus, H Plauchu, M E M Porteous, R E Pyeritz, D A Ross, C Sabba, K Swanson, P Terry, M C Wallace, C J J Westermann, R I White, L H Young, R Zarrabeitia, HHT Foundation International - Guidelines Working Group

Author Affiliations

1: Division of Respirology, Department of Medicine, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada. faughnanm@smh.ca

Associated clinical trials:

Evaluation of Video-assisted Instructions of Nasal Self-packing in Patients With HHT | NCT03841422

Articles citing this

ACG clinical guideline: Genetic testing and management of hereditary gastrointestinal cancer syndromes. Am J Gastroenterol (2015) 3.19

Pulmonary arteriovenous malformations. Am J Respir Crit Care Med (2014) 1.65

Efficacy and safety of thalidomide for the treatment of severe recurrent epistaxis in hereditary haemorrhagic telangiectasia: results of a non-randomised, single-centre, phase 2 study. Lancet Haematol (2015) 1.45

Hemorrhage-adjusted iron requirements, hematinics and hepcidin define hereditary hemorrhagic telangiectasia as a model of hemorrhagic iron deficiency. PLoS One (2013) 1.28

Management of pulmonary arteriovenous malformations. Semin Intervent Radiol (2011) 1.22

Hereditary hemorrhagic telangiectasia: genetics and molecular diagnostics in a new era. Front Genet (2015) 1.18

Mouse and human strategies identify PTPN14 as a modifier of angiogenesis and hereditary haemorrhagic telangiectasia. Nat Commun (2012) 1.13

Arterial oxygen content is precisely maintained by graded erythrocytotic responses in settings of high/normal serum iron levels, and predicts exercise capacity: an observational study of hypoxaemic patients with pulmonary arteriovenous malformations. PLoS One (2014) 1.12

Brain Vascular Malformation Consortium: Overview, Progress and Future Directions. J Rare Disord (2013) 1.12

Ischaemic strokes in patients with pulmonary arteriovenous malformations and hereditary hemorrhagic telangiectasia: associations with iron deficiency and platelets. PLoS One (2014) 1.09

Brain arteriovenous malformation multiplicity predicts the diagnosis of hereditary hemorrhagic telangiectasia: quantitative assessment. Stroke (2011) 1.07

Natural history and outcome of hepatic vascular malformations in a large cohort of patients with hereditary hemorrhagic teleangiectasia. Dig Dis Sci (2011) 1.06

A long diagnostic delay in patients with Hereditary Haemorrhagic Telangiectasia: a questionnaire-based retrospective study. Orphanet J Rare Dis (2012) 1.05

Update on molecular diagnosis of hereditary hemorrhagic telangiectasia. Hum Genet (2010) 1.03

Brain arteriovenous malformations associated with hereditary hemorrhagic telangiectasia: gene-phenotype correlations. Am J Med Genet A (2012) 0.97

Why is genetic screening for autosomal dominant disorders underused in families? The case of hereditary hemorrhagic telangiectasia. Genet Med (2011) 0.96

The use of US health insurance data for surveillance of rare disorders: hereditary hemorrhagic telangiectasia. Genet Med (2013) 0.94

Two cases of high output heart failure caused by hereditary hemorrhagic telangiectasia. Korean Circ J (2012) 0.93

Optimal management of hereditary hemorrhagic telangiectasia. J Blood Med (2014) 0.91

Juvenile polyposis, hereditary hemorrhagic telangiectasia, and early onset colorectal cancer in patients with SMAD4 mutation. J Gastroenterol (2012) 0.89

Specific cancer rates may differ in patients with hereditary haemorrhagic telangiectasia compared to controls. Orphanet J Rare Dis (2013) 0.89

5'UTR mutations of ENG cause hereditary hemorrhagic telangiectasia. Orphanet J Rare Dis (2011) 0.89

Pulmonary arteriovenous malformations presenting as difficult-to-control asthma: a case report. J Med Case Rep (2013) 0.88

Thoracic aortic disease in two patients with juvenile polyposis syndrome and SMAD4 mutations. Am J Med Genet A (2012) 0.86

Appreciating the broad clinical features of SMAD4 mutation carriers: a multicenter chart review. Genet Med (2014) 0.86

Targeting under-diagnosis in hereditary hemorrhagic telangiectasia: a model approach for rare diseases? Orphanet J Rare Dis (2014) 0.83

Connective tissue disorders and cardiovascular complications: the indomitable role of transforming growth factor-beta signaling. Adv Exp Med Biol (2014) 0.83

Impact of pulmonary arteriovenous malformations on respiratory-related quality of life in patients with hereditary haemorrhagic telangiectasia. PLoS One (2014) 0.82

Initial experience with use of hydrogel microcoils in embolization of pulmonary arteriovenous malformations. Springerplus (2014) 0.81

Endoglin: a critical mediator of cardiovascular health. Vasc Health Risk Manag (2013) 0.81

Neurovascular manifestations in hereditary hemorrhagic telangiectasia: imaging features and genotype-phenotype correlations. AJNR Am J Neuroradiol (2015) 0.80

Long non-coding RNA expression profiles in hereditary haemorrhagic telangiectasia. PLoS One (2014) 0.80

Update on Clinical Strategies in Hereditary Hemorrhagic Telangiectasia from an ENT Point of View. Clin Exp Otorhinolaryngol (2016) 0.80

Life expextancy of parents with Hereditary Haemorrhagic Telangiectasia. Orphanet J Rare Dis (2016) 0.79

Complications and mortality in hereditary hemorrhagic telangiectasia: A population-based study. Neurology (2015) 0.79

Conditional knockout of activin like kinase-1 (ALK-1) leads to heart failure without maladaptive remodeling. Heart Vessels (2017) 0.78

The ACVRL1 c.314-35A>G polymorphism is associated with organ vascular malformations in hereditary hemorrhagic telangiectasia patients with ENG mutations, but not in patients with ACVRL1 mutations. Am J Med Genet A (2015) 0.78

HHT diagnosis by Mid-infrared spectroscopy and artificial neural network analysis. Orphanet J Rare Dis (2013) 0.78

Management of patients with hereditary hemorrhagic telangiectasia undergoing general anesthesia: a cohort from a single academic center's experience. J Anesth (2013) 0.78

Interventional treatment of pulmonary arteriovenous malformations. World J Radiol (2010) 0.78

Epistaxis in hereditary hemorrhagic telangiectasia: an evidence based review of surgical management. J Otolaryngol Head Neck Surg (2016) 0.77

Peliosis hepatis associated with hereditary haemorrhagic telangiectasia. Gastroenterol Rep (Oxf) (2013) 0.76

Percutaneous left atrial appendage closure-An alternative strategy for anticoagulation in atrial fibrillation and hereditary hemorrhagic telangiectasia? Cardiovasc Diagn Ther (2015) 0.76

Diagnosis and Treatment of Hereditary Hemorrhagic Telangiectasia. Ochsner J (2017) 0.76

Macro- and microcirculation patterns of intrahepatic blood flow changes in patients with hereditary hemorrhagic telangiectasia. World J Gastroenterol (2017) 0.75

Implications of an Incidental Pulmonary Arteriovenous Malformation. J Investig Med High Impact Case Rep (2016) 0.75

Persistence of pulmonary arteriovenous malformations after successful embolotherapy with Amplatzer vascular plug: long-term results. Diagn Interv Radiol (2016) 0.75

Standard anticoagulation for mesenteric vein thrombosis, revealing a 'zebra' diagnosis: hereditary haemorrhagic telangiectasia--the dripping truth! BMJ Case Rep (2013) 0.75

Health screening behaviors among adults with hereditary hemorrhagic telangiectasia in North America. Genet Med (2016) 0.75

Stroke in hereditary hemorrhagic telangiectasia patients. New evidence for repeated screening and early treatment of pulmonary vascular malformations: two case reports. BMC Neurol (2011) 0.75

Primary biliary cirrhosis and hereditary hemorrhagic telangiectasia: When two rare diseases coexist. World J Hepatol (2013) 0.75

Diagnosis and treatment of hereditary hemorrhagic telangiectasia in a pediatric patient with chronic cyanosis. Images Paediatr Cardiol (2017) 0.75

Bleeding and clotting in hereditary hemorrhagic telangiectasia. World J Clin Cases (2015) 0.75

Carotid ultrasound for pulmonary arteriovenous malformation screening. Open Med (Wars) (2015) 0.75

Hypogonadotropic hypogonadism associated with hereditary hemorrhagic telangiectasia [corrected]. Case Rep Endocrinol (2013) 0.75

Hereditary haemorrhagic telangiectasia. BMJ Case Rep (2015) 0.75

Effect of pulmonary arteriovenous malformations on the mechanical properties of the lungs. BMC Pulm Med (2017) 0.75

Quality of life in patients with hereditary haemorrhagic telangiectasia (HHT). Health Qual Life Outcomes (2017) 0.75

Pulmonary arteriovenous malformation: a rare cause of dyspnoea on exertion. BMJ Case Rep (2014) 0.75

A postal survey of hereditary hemorrhagic telangectasia in the northeast of England. Allergy Rhinol (Providence) (2015) 0.75

Research on potential biomarkers in hereditary hemorrhagic telangiectasia. Front Genet (2015) 0.75

Hereditary Hemorrhagic Telangiectasia and Myocardial Infarction. Int J Angiol (2015) 0.75

Rare manifestations in a case of Osler-Weber-Rendu disease. BMJ Case Rep (2015) 0.75

Definite hereditary hemorrhagic telangiectasia in a 60-year-old black Kenyan woman: a case report. J Med Case Rep (2016) 0.75

Hereditary Hemorrhagic Telangiectasia with Hepatic Vascular Malformations. Case Rep Med (2015) 0.75

Genetic variation in the functional ENG allele inherited from the non-affected parent associates with presence of pulmonary arteriovenous malformation in hereditary hemorrhagic telangiectasia 1 (HHT1) and may influence expression of PTPN14. Front Genet (2015) 0.75

A spinal arteriovenous fistula in a 3-year old boy. Case Rep Pediatr (2014) 0.75

Management of pulmonary arteriovenous malformations in hereditary hemorrhagic telangiectasia patients. Semin Intervent Radiol (2013) 0.75

Severe, chronic cough caused by pulmonary arteriovenous malformations in a patient with hereditary haemorrhagic telangiectasia: case report. BMC Pulm Med (2015) 0.75

Spinal arteriovenous fistulae in patients with hereditary hemorrhagic telangiectasia: A case report and systematic review of the literature. Interv Neuroradiol (2016) 0.75

Pulmonary arteriovenous malformations presenting as refractory heart failure. J Thorac Dis (2014) 0.75

Dyspnea with anemia turned out to be a case of hereditary hemorrhagic telangiectasia. Asian J Transfus Sci (2013) 0.75

20-year follow-up study of Danish HHT patients-survival and causes of death. Orphanet J Rare Dis (2016) 0.75

High-Output Heart Failure Contributing to Recurrent Epistaxis Kiesselbach Area Syndrome in a Patient With Hereditary Hemorrhagic Telangiectasia. J Investig Med High Impact Case Rep (2017) 0.75

Clinical and genetic challenges in a family with history of childhood polyp, aortopathy, and clinical diagnosis of hereditary hemorrhagic teleangiectasia (HHT). Ann Pediatr Cardiol (2016) 0.75

A case of Multiple Unilateral Pulmonary arteriovenous Malformation Relapse: Efficacy of embolization treatment. Open Med (Wars) (2015) 0.75

Pulmonary arteriovenous malformation-etiology, clinical four case presentations and review of the literature. Ann Transl Med (2015) 0.75

Brain Abscesses Associated with Asymptomatic Pulmonary Arteriovenous Fistulas. J Korean Neurosurg Soc (2016) 0.75

Severity score for hereditary hemorrhagic telangiectasia. Orphanet J Rare Dis (2014) 0.75

Pulmonary hypertension in hereditary haemorrhagic telangiectasia. World J Cardiol (2015) 0.75

Hereditary Hemorrhagic Telangiectasia: Breakpoint Characterization of a Novel Large Deletion in ACVRL1 Suggests the Causing Mechanism. Mol Syndromol (2013) 0.75

Bevacizumab as a treatment for hereditary hemorrhagic telangiectasia in children: a case report. Colomb Med (Cali) (2017) 0.75

Influence of temporary nasal occlusion (tNO) on epistaxis frequency in patients with hereditary hemorrhagic telangiectasia (HHT). Eur Arch Otorhinolaryngol (2017) 0.75

Hereditary hemorrhagic telangiectasia and pregnancy: potential adverse events and pregnancy outcomes. Int J Womens Health (2017) 0.75

Familial cerebral abscesses caused by hereditary hemorrhagic telangiectasia. Clin Case Rep (2017) 0.75

Gastrointestinal Manifestations of Hereditary Hemorrhagic Telangiectasia (HHT): A Systematic Review of the Literature. Dig Dis Sci (2017) 0.75

Contemporary Management of Pulmonary Arteriovenous Malformations. Int J Angiol (2017) 0.75

Vein Diameter on Unenhanced Multidetector CT Predicts Reperfusion of Pulmonary Arteriovenous Malformation after Embolotherapy. Eur Radiol (2015) 0.75

A 58-year-old woman with hypoxia, hypoxaemia, a hole in the heart and a … herring! Intracardiac or extracardiac shunt? That is the question! BMJ Case Rep (2015) 0.75

Juvenile stroke in combined syndrome of hereditary hemorrhagic telangiectasia and juvenile polyposis. Neurol Sci (2014) 0.75

Articles by these authors

A gene map of the human genome. Science (1996) 14.32

Marfan syndrome caused by a recurrent de novo missense mutation in the fibrillin gene. Nature (1991) 11.44

Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta. Nat Med (1999) 9.73

Electrical studies on the frog's labyrinth. J Physiol (1936) 9.01

Diagnostic criteria for hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber syndrome). Am J Med Genet (2000) 8.78

The diagnostic evaluation and multidisciplinary management of neurofibromatosis 1 and neurofibromatosis 2. JAMA (1997) 8.30

Revised diagnostic criteria for the Marfan syndrome. Am J Med Genet (1996) 7.84

Hereditary hemorrhagic telangiectasia. N Engl J Med (1995) 6.91

The Marfan syndrome: diagnosis and management. N Engl J Med (1979) 6.49

Mutations in the activin receptor-like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2. Nat Genet (1996) 5.15

Progression of aortic dilatation and the benefit of long-term beta-adrenergic blockade in Marfan's syndrome. N Engl J Med (1994) 5.03

The natural history of homocystinuria due to cystathionine beta-synthase deficiency. Am J Hum Genet (1985) 4.60

The skipping of constitutive exons in vivo induced by nonsense mutations. Science (1993) 4.41

BRCA1 mutations in women attending clinics that evaluate the risk of breast cancer. N Engl J Med (1997) 4.33

Replacement of the aortic root in patients with Marfan's syndrome. N Engl J Med (1999) 4.17

Canadian guidelines for the initial management of community-acquired pneumonia: an evidence-based update by the Canadian Infectious Diseases Society and the Canadian Thoracic Society. The Canadian Community-Acquired Pneumonia Working Group. Clin Infect Dis (2000) 4.01

Percutaneous RF interstitial thermal ablation in the treatment of hepatic cancer. AJR Am J Roentgenol (1996) 3.93

Dust exposure and mortality in an American chrysotile textile plant. Br J Ind Med (1983) 3.80

Immunohistologic abnormalities of the microfibrillar-fiber system in the Marfan syndrome. N Engl J Med (1990) 3.63

Percutaneous balloon valvuloplasty: a new method for treating congenital pulmonary-valve stenosis. N Engl J Med (1982) 3.51

Chronic activation of AMP kinase results in NRF-1 activation and mitochondrial biogenesis. Am J Physiol Endocrinol Metab (2001) 3.45

Mutations in the human gene for fibrillin-1 (FBN1) in the Marfan syndrome and related disorders. Hum Mol Genet (1995) 3.42

"A bit more truthful": the validity of adolescent sexual behaviour data collected in rural northern Tanzania using five methods. Sex Transm Infect (2004) 3.37

The North American Symptomatic Carotid Endarterectomy Trial : surgical results in 1415 patients. Stroke (1999) 3.31

Corticosteroid therapy of alcoholic hepatitis. Gastroenterology (1978) 3.21

Rapid development of ciprofloxacin resistance in methicillin-susceptible and -resistant Staphylococcus aureus. J Infect Dis (1991) 3.12

OBSERVATIONS ON THE FUNCTION OF PYRIDOXAL-5-PHOSPHATE IN PHOSPHORYLASE. Proc Natl Acad Sci U S A (1958) 3.07

The efficacy of surgical modifications of the upper airway in adults with obstructive sleep apnea syndrome. Sleep (1996) 3.03

Role of angiography following aneurysm surgery. J Neurosurg (1993) 3.02

Hemodynamic events in a prospective randomized trial of propranolol versus placebo in the prevention of a first variceal hemorrhage. Gastroenterology (1990) 2.99

Effect of mutation type and location on clinical outcome in 1,013 probands with Marfan syndrome or related phenotypes and FBN1 mutations: an international study. Am J Hum Genet (2007) 2.91

European Respiratory Society guidelines for the diagnosis and management of lymphangioleiomyomatosis. Eur Respir J (2010) 2.86

Positional cloning of the mouse saccharin preference (Sac) locus. Chem Senses (2001) 2.75

Pulmonary arteriovenous malformations: techniques and long-term outcome of embolotherapy. Radiology (1988) 2.66

Clinical responses to bone marrow transplantation in children with severe osteogenesis imperfecta. Blood (2001) 2.65

Conservative treatment of mild/moderate cervical dyskaryosis: long-term outcome. Lancet (1992) 2.64

Fire on an intensive care unit caused by an oxygen cylinder. Anaesthesia (2012) 2.61

Surgical treatment of aneurysms of the ascending aorta in the Marfan syndrome. Results of composite-graft repair in 50 patients. N Engl J Med (1986) 2.59

Delayed ipsilateral parenchymal hemorrhage following flow diversion for the treatment of anterior circulation aneurysms. AJNR Am J Neuroradiol (2012) 2.49

Translocation of myocardial GLUT-4 and increased glucose uptake through activation of AMPK by AICAR. Am J Physiol (1999) 2.44

Four novel FBN1 mutations: significance for mutant transcript level and EGF-like domain calcium binding in the pathogenesis of Marfan syndrome. Genomics (1993) 2.43

Experimental allergic encephalomyelitis and multiple sclerosis: lesion characterization with magnetization transfer imaging. Radiology (1992) 2.41

Functional organelles in prokaryotes: polyhedral inclusions (carboxysomes) of Thiobacillus neapolitanus. Science (1973) 2.39

Separable regulatory elements governing myogenin transcription in mouse embryogenesis. Science (1993) 2.36

Percutaneous radiofrequency interstitial thermal ablation in the treatment of small hepatocellular carcinoma. Cancer J Sci Am (2006) 2.32

A molecular approach to the stratification of cardiovascular risk in families with Marfan's syndrome. N Engl J Med (1994) 2.29

Staging of mediastinal non-small cell lung cancer with FDG PET, CT, and fusion images: preliminary prospective evaluation. Radiology (1994) 2.28

Fatty fish consumption and risk of prostate cancer. Lancet (2001) 2.27

Percutaneous treatment of small hepatic tumors by an expandable RF needle electrode. AJR Am J Roentgenol (1998) 2.23

A unique point mutation in the fibroblast growth factor receptor 3 gene (FGFR3) defines a new craniosynostosis syndrome. Am J Hum Genet (1997) 2.22

Percutaneous transluminal balloon valvuloplasty for pulmonary valve stenosis. Circulation (1984) 2.21

Deficiency of protein C in patients with portal vein thrombosis. Hepatology (1988) 2.19

Pulmonary arteriovenous malformations: cerebral ischemia and neurologic manifestations. Neurology (2000) 2.18

Liver disease in patients with hereditary hemorrhagic telangiectasia. N Engl J Med (2000) 2.14

Association of mitral valve prolapse and systemic abnormalities of connective tissue. A phenotypic continuum. JAMA (1989) 2.12

A national agenda for public health informatics. J Public Health Manag Pract (2001) 2.12

The Stickler syndrome: evidence for close linkage to the structural gene for type II collagen. Genomics (1987) 2.11

Effect of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside infusion on in vivo glucose and lipid metabolism in lean and obese Zucker rats. Diabetes (2001) 2.10

Magnetic resonance evaluation of ventrolateral medullary compression in essential hypertension. J Neurosurg (1998) 2.10

Portal pressure, presence of gastroesophageal varices and variceal bleeding. Hepatology (1985) 2.09

The incidence of divorce within cohorts of American marriages contracted since the Civil War. Demography (1979) 2.08

Percutaneous radiofrequency ablation of small hepatocellular carcinoma: long-term results. Eur Radiol (2001) 2.03

Pressure gradients without obstruction. A new concept of "hypertrophic subaortic stenosis". Circulation (1965) 2.03

Mitochondrial transfer ribonucleic acids. Proc Natl Acad Sci U S A (1967) 2.02

Expression of the erythropoietin gene. Mol Cell Biol (1986) 2.02

Enhanced radiometric detection of Mycobacterium paratuberculosis by using filter-concentrated bovine fecal specimens. J Clin Microbiol (1990) 2.02

Fifteen novel FBN1 mutations causing Marfan syndrome detected by heteroduplex analysis of genomic amplicons. Am J Hum Genet (1995) 2.01

A gene for hereditary multiple exostoses maps to chromosome 19p. Hum Mol Genet (1994) 2.00

Infliximab and other immunomodulating drugs in patients with inflammatory bowel disease and the risk of serious bacterial infections. Aliment Pharmacol Ther (2009) 1.98

Motivations and perceptions of early adopters of personalized genomics: perspectives from research participants. Public Health Genomics (2011) 1.96

Is prevalence of diarrhea a better predictor of subsequent mortality and weight gain than diarrhea incidence? Am J Epidemiol (1996) 1.95

The malignancy-sarcoidosis syndrome. Chest (1990) 1.93

Sepsis in cirrhosis: report on the 7th meeting of the International Ascites Club. Gut (2005) 1.93

Accuracy of reporting of family history of colorectal cancer. Gut (2004) 1.92

Outpatient liver biopsy: how safe is it? Ann Intern Med (1993) 1.90

Sleep-wake disorders based on a polysomnographic diagnosis. A national cooperative study. JAMA (1982) 1.90

Mitochondrial-specific aminoacyl-RNA synthetases. Proc Natl Acad Sci U S A (1967) 1.90

Improved method for bacteriological diagnosis of spontaneous bacterial peritonitis. J Clin Microbiol (1989) 1.90

The Marfan syndrome in early childhood: analysis of 15 patients diagnosed at less than 4 years of age. Am J Cardiol (1983) 1.87

Empowering primary care health professionals in medical genetics: how soon? How fast? How far? Am J Med Genet (2001) 1.86

Aortic root replacement. Risk factor analysis of a seventeen-year experience with 270 patients. J Thorac Cardiovasc Surg (1995) 1.86

Categorization of hospital emergency services--developing valid criteria. West J Med (1987) 1.85

Aerosol pentamidine for secondary prophylaxis of AIDS-related Pneumocystis carinii pneumonia. A randomized, placebo-controlled study. Ann Intern Med (1991) 1.84

The effect of different sensitivity, specificity and cause-specific mortality fractions on the estimation of differences in cause-specific mortality rates in children from studies using verbal autopsies. Int J Epidemiol (1997) 1.84

Adenoid cystic carcinoma: a retrospective clinical review. Int J Cancer (2001) 1.83

Bronchoscopic needle aspiration biopsy of paratracheal tumors. Am Rev Respir Dis (1978) 1.83

The economics of clinical genetics services. III. Cognitive genetics services are not self-supporting. Am J Hum Genet (1989) 1.82

Risk factors for uterine rupture and neonatal consequences of uterine rupture: a population-based study of successive pregnancies in Sweden. BJOG (2007) 1.80

Duty to re-contact. Genet Med (2001) 1.80

Genome-tagged mice (GTM): two sets of genome-wide congenic strains. Genomics (2001) 1.79

Treatment of restenosis of coarctation by percutaneous transluminal angioplasty. Circulation (1983) 1.79

What to advise patients about drinking alcohol. The clinician's conundrum. JAMA (1994) 1.78

Electrophoretic analysis of multiple forms of myosin in fast-twitch and slow-twitch muscles of the chick. Biochem J (1976) 1.78

Pediatric Investigators Collaborative Network on Infections in Canada (PICNIC) study of admission and management variation in patients hospitalized with respiratory syncytial viral lower respiratory tract infection. J Pediatr (1996) 1.77

Genotype-phenotype relationship in hereditary haemorrhagic telangiectasia. J Med Genet (2005) 1.76

Vitamin A supplementation and childhood malaria in northern Ghana. Am J Clin Nutr (1995) 1.76