PubRank

Roland Brock

Author PubWeight™ 66.21‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Autophagy promotes MHC class II presentation of peptides from intracellular source proteins. Proc Natl Acad Sci U S A 2005 3.75
2 A comprehensive model for the cellular uptake of cationic cell-penetrating peptides. Traffic 2007 3.01
3 High-affinity adaptors for switchable recognition of histidine-tagged proteins. J Am Chem Soc 2005 2.06
4 Toll-like receptor 6-independent signaling by diacylated lipopeptides. Eur J Immunol 2005 1.84
5 TLR1- and TLR6-independent recognition of bacterial lipopeptides. J Biol Chem 2006 1.80
6 Break on through to the other side-biophysics and cell biology shed light on cell-penetrating peptides. Chembiochem 2005 1.77
7 Auxin transport inhibitors impair vesicle motility and actin cytoskeleton dynamics in diverse eukaryotes. Proc Natl Acad Sci U S A 2008 1.74
8 A stepwise dissection of the intracellular fate of cationic cell-penetrating peptides. J Biol Chem 2004 1.72
9 Lipopeptide structure determines TLR2 dependent cell activation level. FEBS J 2005 1.28
10 Natural killer cell signal integration balances synapse symmetry and migration. PLoS Biol 2009 1.22
11 Extending the applicability of carboxyfluorescein in solid-phase synthesis. Bioconjug Chem 2003 1.02
12 Detection and manipulation of mitochondrial reactive oxygen species in mammalian cells. Biochim Biophys Acta 2010 1.01
13 Red blood cell deformability during storage: towards functional proteomics and metabolomics in the Blood Bank. Blood Transfus 2012 1.01
14 Synthetic lipopeptide adjuvants and Toll-like receptor 2--structure-activity relationships. Vaccine 2004 1.01
15 Cationic cell-penetrating peptides interfere with TNF signalling by induction of TNF receptor internalization. J Cell Sci 2005 1.01
16 A quantitative validation of fluorophore-labelled cell-permeable peptide conjugates: fluorophore and cargo dependence of import. Biochim Biophys Acta 2002 0.98
17 A CD14 domain with lipopolysaccharide-binding and -neutralizing activity. Chembiochem 2006 0.95
18 A cell-penetrating peptide derived from human lactoferrin with conformation-dependent uptake efficiency. J Biol Chem 2009 0.92
19 Cationic cell-penetrating peptides induce ceramide formation via acid sphingomyelinase: implications for uptake. J Control Release 2010 0.91
20 Molecular parameters of siRNA--cell penetrating peptide nanocomplexes for efficient cellular delivery. ACS Nano 2013 0.90
21 Preferential uptake of L- versus D-amino acid cell-penetrating peptides in a cell type-dependent manner. Chem Biol 2011 0.90
22 Solute diffusion is hindered in the mitochondrial matrix. Proc Natl Acad Sci U S A 2011 0.89
23 Protein expression from exogenous mRNA: uptake by receptor-mediated endocytosis and trafficking via the lysosomal pathway. RNA Biol 2011 0.88
24 Gateway to understanding microparticles: standardized isolation and identification of plasma membrane-derived vesicles. Nanomedicine (Lond) 2013 0.88
25 Geometry sensing by dendritic cells dictates spatial organization and PGE(2)-induced dissolution of podosomes. Cell Mol Life Sci 2011 0.87
26 Cellular integration of an enzyme-loaded polymersome nanoreactor. Angew Chem Int Ed Engl 2010 0.86
27 Simultaneous detection of intracellular target and off-target binding of small molecule cancer drugs at nanomolar concentrations. Br J Pharmacol 2010 0.85
28 A targeted protease substrate for a quantitative determination of protease activities in the endolysosomal pathway. Chembiochem 2006 0.85
29 Multivalent design of apoptosis-inducing bid-BH3 peptide-oligosaccharides boosts the intracellular activity at identical overall peptide concentrations. Chemistry 2012 0.84
30 One-step analysis of protein complexes in microliters of cell lysate. Nat Methods 2005 0.83
31 Biological responses towards cationic peptides and drug carriers. Trends Pharmacol Sci 2010 0.83
32 Stabilization of peptides for intracellular applications by phosphoramidate-linked polyethylene glycol chains. Angew Chem Int Ed Engl 2013 0.83
33 Lipolanthionine peptides act as inhibitors of TLR2-mediated IL-8 secretion. Synthesis and structure-activity relationships. J Med Chem 2006 0.82
34 The stoichiometry of peptide-heparan sulfate binding as a determinant of uptake efficiency of cell-penetrating peptides. Cell Mol Life Sci 2013 0.82
35 Structure property analysis of pentamethine indocyanine dyes: identification of a new dye for life science applications. Bioconjug Chem 2004 0.82
36 Coupling to polymeric scaffolds stabilizes biofunctional peptides for intracellular applications. Mol Pharmacol 2011 0.82
37 Peptide microarrays for the profiling of cytotoxic T-lymphocyte activity using minimum numbers of cells. Cancer Immunol Immunother 2010 0.81
38 Exploration of the design principles of a cell-penetrating bicylic peptide scaffold. Bioconjug Chem 2014 0.81
39 Label-free characterization of cell adhesion using reflectometric interference spectroscopy (RIfS). Anal Bioanal Chem 2005 0.80
40 A doubly labeled penetratin analogue as a ratiometric sensor for intracellular proteolytic stability. Bioconjug Chem 2010 0.80
41 Determination of binding constants on microarrays with confocal fluorescence detection. Anal Chem 2003 0.80
42 Quantitative glucose and ATP sensing in mammalian cells. Pharm Res 2011 0.80
43 Selectivity of competitive multivalent interactions at interfaces. Chembiochem 2009 0.80
44 A network analysis of changes in molecular interactions in cellular signaling. Mol Cell Proteomics 2006 0.79
45 The intracellular pharmacokinetics of terminally capped peptides. Mol Pharm 2012 0.79
46 The in vitro biological activity of the HLA-DR-binding clinical IgG4 antibody 1D09C3 is a consequence of the disruption of cell aggregates and can be abrogated by Fab arm exchange. Mol Immunol 2009 0.79
47 The activity of lipopeptide TLR2 agonists critically depends on the presence of solubilizers. Eur J Immunol 2007 0.79
48 Diffusion-driven device for a high-resolution dose-response profiling of combination chemotherapy. Anal Chem 2009 0.78
49 Chemolabile cellular microarrays for screening small molecules and peptides. Mol Divers 2004 0.78
50 HPMA as a scaffold for the modular assembly of functional peptide polymers by native chemical ligation. Bioconjug Chem 2008 0.78
51 Chemical inhibitors when timing is critical: a pharmacological concept for the maturation of T cell contacts. Chembiochem 2005 0.78
52 Multivalence and spot heterogeneity in microarray-based measurement of binding constants. Anal Bioanal Chem 2007 0.78
53 Peptide microarrays for the detection of molecular interactions in cellular signal transduction. Proteomics 2005 0.78
54 Measurements of the intracellular stability of CPPs. Methods Mol Biol 2011 0.77
55 A fluorescence-based synthetic LPS sensor. J Am Chem Soc 2007 0.77
56 Intracellular concentration measurements in adherent cells: a comparison of import efficiencies of cell-permeable peptides. Biol Chem 2002 0.77
57 Peptide microarrays to probe for competition for binding sites in a protein interaction network. J Proteomics 2013 0.77
58 A modular and noncovalent transduction system for leucine-zipper-tagged proteins. Chembiochem 2011 0.77
59 One-step analysis of protein complexes in microliters of cell lysate using indirect immunolabeling & fluorescence cross-correlation spectroscopy. Nat Protoc 2006 0.77
60 Cell surface clustering of heparan sulfate proteoglycans by amphipathic cell-penetrating peptides does not contribute to uptake. J Control Release 2013 0.77
61 Activation of cell-penetrating peptides by disulfide bridge formation of truncated precursors. Chem Commun (Camb) 2014 0.76
62 Construction of a microstructured collagen membrane mimicking the papillary dermis architecture and guiding keratinocyte morphology and gene expression. Macromol Biosci 2012 0.76
63 A postcolumn alkalinization procedure enhances the sensitivity of fluorescence detection of fluorescein-labeled substances in RP-HPLC. Anal Biochem 2005 0.76
64 A quantitative assessment of costimulation and phosphatase activity on microclusters in early T cell signaling. PLoS One 2013 0.75
65 Analyzing the homeostasis of signaling proteins by a combination of Western blot and fluorescence correlation spectroscopy. Biophys J 2011 0.75
66 Methods to Study the Role of the Glycocalyx in the Uptake of Cell-Penetrating Peptides. Methods Mol Biol 2015 0.75
67 A peptide-functionalized polymer as a minimal scaffold protein to enhance cluster formation in early T cell signal transduction. Chembiochem 2015 0.75
68 Reversible cross-linking of hyperbranched polymers: a strategy for the combinatorial decoration of multivalent scaffolds. Angew Chem Int Ed Engl 2005 0.75
69 Stereoselective uptake of cell-penetrating peptides is conserved in antisense oligonucleotide polyplexes. Small 2014 0.75
70 Lipoconjugates for the noncovalent generation of microarrays in biochemical and cellular assays. Chembiochem 2002 0.75
71 Stimulus dependence of the action of small-molecule inhibitors in the CD3/CD28 signalling network. ChemMedChem 2008 0.75
72 Structural variation of cationic lipids: minimum requirement for improved oligonucleotide delivery into cells. J Control Release 2005 0.75
73 A Conjugate of an anti-EGFR VHH and a Cell-penetrating Peptide Drives Receptor Internalization and Blocks EGFR Activation. Chembiochem 2017 0.75
74 Modulation of neuronal activity by the endogenous pentapeptide QYNAD. Eur J Neurosci 2003 0.75