Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Photodynamic therapy in the treatment of microbial infections: basic principles and perspective applications.
|
Lasers Surg Med
|
2006
|
2.27
|
2
|
Synthesis and antibacterial activity of new poly-S-lysine-porphyrin conjugates.
|
J Med Chem
|
2004
|
1.10
|
3
|
Novel N1-substituted 1,3-dihydro-2H-benzimidazol-2-ones as potent non-nucleoside reverse transcriptase inhibitors.
|
Bioorg Med Chem
|
2008
|
1.09
|
4
|
Pharmacophore-based design of HIV-1 integrase strand-transfer inhibitors.
|
J Med Chem
|
2005
|
1.04
|
5
|
Pharmacophore-based discovery of small-molecule inhibitors of protein-protein interactions between HIV-1 integrase and cellular cofactor LEDGF/p75.
|
ChemMedChem
|
2009
|
1.01
|
6
|
Human immunodeficiency virus integrase inhibitors efficiently suppress feline immunodeficiency virus replication in vitro and provide a rationale to redesign antiretroviral treatment for feline AIDS.
|
Retrovirology
|
2007
|
0.95
|
7
|
Preclinical evaluation of 1H-benzylindole derivatives as novel human immunodeficiency virus integrase strand transfer inhibitors.
|
Antimicrob Agents Chemother
|
2008
|
0.84
|
8
|
Small molecules targeting the interaction between HIV-1 integrase and LEDGF/p75 cofactor.
|
Bioorg Med Chem
|
2010
|
0.83
|
9
|
Inhibitors of the interactions between HIV-1 IN and the cofactor LEDGF/p75.
|
ChemMedChem
|
2011
|
0.83
|
10
|
HIV-1 integrase strand-transfer inhibitors: design, synthesis and molecular modeling investigation.
|
Eur J Med Chem
|
2010
|
0.83
|
11
|
A refined pharmacophore model for HIV-1 integrase inhibitors: Optimization of potency in the 1H-benzylindole series.
|
Bioorg Med Chem Lett
|
2008
|
0.82
|
12
|
New cationic liposomes as vehicles of m-tetrahydroxyphenylchlorin in photodynamic therapy of infectious diseases.
|
Mol Pharm
|
2008
|
0.81
|
13
|
Design, synthesis, and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents.
|
Bioorg Med Chem
|
2009
|
0.81
|
14
|
4-[1-(4-Fluorobenzyl)-4-hydroxy-1H-indol-3-yl]-2-hydroxy-4-oxobut-2-enoic acid as a prototype to develop dual inhibitors of HIV-1 integration process.
|
Antiviral Res
|
2011
|
0.79
|
15
|
New scaffolds of natural origin as Integrase-LEDGF/p75 interaction inhibitors: virtual screening and activity assays.
|
Eur J Med Chem
|
2013
|
0.78
|
16
|
Identification of 3,4-Dihydroisoquinoline-2(1H)-sulfonamides as potent carbonic anhydrase inhibitors: synthesis, biological evaluation, and enzyme--ligand X-ray studies.
|
J Med Chem
|
2010
|
0.78
|
17
|
Structure-based pharmacophore identification of new chemical scaffolds as non-nucleoside reverse transcriptase inhibitors.
|
J Chem Inf Model
|
2007
|
0.78
|
18
|
Synthesis and biological characterization of 3-substituted 1H-indoles as ligands of GluN2B-containing N-methyl-D-aspartate receptors. Part 2.
|
J Med Chem
|
2012
|
0.77
|
19
|
Synthesis, structure-activity relationship studies, and X-ray crystallographic analysis of arylsulfonamides as potent carbonic anhydrase inhibitors.
|
J Med Chem
|
2012
|
0.76
|
20
|
Fragment hopping approach directed at design of HIV IN-LEDGF/p75 interaction inhibitors.
|
J Enzyme Inhib Med Chem
|
2012
|
0.76
|
21
|
Computational studies to discover a new NR2B/NMDA receptor antagonist and evaluation of pharmacological profile.
|
ChemMedChem
|
2008
|
0.76
|
22
|
Development of 3-substituted-1H-indole derivatives as NR2B/NMDA receptor antagonists.
|
Bioorg Med Chem
|
2008
|
0.75
|
23
|
Targeting GluN2B-containing N-Methyl-D-aspartate receptors: design, synthesis, and binding affinity evaluation of novel 3-substituted indoles.
|
Arch Pharm (Weinheim)
|
2014
|
0.75
|
24
|
Combined strategies for the discovery of ionotropic glutamate receptor antagonists.
|
ChemMedChem
|
2009
|
0.75
|
25
|
Synthesis and biological characterization of 3-substituted-1H-indoles as ligands of GluN2B-containing N-methyl-D-aspartate receptors.
|
J Med Chem
|
2011
|
0.75
|
26
|
Identification of potent and selective human carbonic anhydrase VII (hCA VII) inhibitors.
|
ChemMedChem
|
2010
|
0.75
|
27
|
Synthesis and biological profile of new 1,2,3,4-tetrahydroisoquinolines as selective carbonic anhydrase inhibitors.
|
Bioorg Med Chem
|
2011
|
0.75
|
28
|
Novel 1,3-dihydro-benzimidazol-2-ones and their analogues as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
|
Bioorg Med Chem
|
2010
|
0.75
|
29
|
Accumulation and effects of sulfadimethoxine in Salix fragilis L. plants: a preliminary study to phytoremediation purposes.
|
Int J Phytoremediation
|
2012
|
0.75
|
30
|
Synthesis and evaluation of pharmacological profile of 1-aryl-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamides.
|
Bioorg Med Chem
|
2009
|
0.75
|
31
|
Synthesis and structure-active relationship of 1-aryl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline anticonvulsants.
|
Chem Pharm Bull (Tokyo)
|
2010
|
0.75
|
32
|
Indole derivatives as dual-effective agents for the treatment of neurodegenerative diseases: synthesis, biological evaluation, and molecular modeling studies.
|
Bioorg Med Chem
|
2013
|
0.75
|