Published in BMJ on June 30, 2009
Acute infective conjunctivitis in primary care: who needs antibiotics? An individual patient data meta-analysis. Br J Gen Pract (2011) 1.59
"One-size-fits-all"? Optimizing treatment duration for bacterial infections. PLoS One (2012) 1.05
Beta- lactam antibiotics stimulate biofilm formation in non-typeable haemophilus influenzae by up-regulating carbohydrate metabolism. PLoS One (2014) 0.83
Parents' beliefs and knowledge about the management of acute otitis media: a qualitative study. BMC Fam Pract (2015) 0.80
Antibiotic Treatment for First Episode of Acute Otitis Media Is Not Associated with Future Recurrences. PLoS One (2016) 0.75
Amoxicillin treatment increases rate of late recurrence of acute otitis media in young children. J Pediatr (2010) 0.75
Antibiotic Use in Children with Acute Respiratory or Ear Infections: Prospective Observational Comparison of Anthroposophic and Conventional Treatment under Routine Primary Care Conditions. Evid Based Complement Alternat Med (2014) 0.75
The evidence for applying Streptococcus salivarius 24SMB by nasal spray for preventing recurrent acute otitis media. Eur J Clin Microbiol Infect Dis (2016) 0.75
Open randomised trial of prescribing strategies in managing sore throat. BMJ (1997) 11.35
Diagnosis and management of acute otitis media. Pediatrics (2004) 7.80
Antibiotics for acute otitis media: a meta-analysis with individual patient data. Lancet (2006) 5.83
Penicillin for acute sore throat: randomised double blind trial of seven days versus three days treatment or placebo in adults. BMJ (2000) 4.61
Primary care based randomised, double blind trial of amoxicillin versus placebo for acute otitis media in children aged under 2 years. BMJ (2000) 4.58
Antibiotics for acute otitis media in children. Cochrane Database Syst Rev (2004) 4.53
Otitis media. Lancet (2004) 3.71
Acute red ear in children: controlled trial of non-antibiotic treatment in general practice. BMJ (1991) 2.52
Consultations for middle ear disease, antibiotic prescribing and risk factors for reattendance: a case-linked cohort study. Br J Gen Pract (2006) 1.95
Antibiotic treatment in acute Otitis Media promotes superinfection with resistant Streptococcus pneumoniae carried before initiation of treatment. J Infect Dis (2001) 1.14
A single intramuscular dose of ceftriaxone changes nasopharyngeal bacterial flora in children with acute otitis media. Acta Paediatr (2000) 1.04
Long-term prognosis of acute otitis media in infancy: determinants of recurrent acute otitis media and persistent middle ear effusion. Fam Pract (2005) 1.04
Systematic review of factors contributing to penicillin treatment failure in Streptococcus pyogenes pharyngitis. Otolaryngol Head Neck Surg (2007) 1.02
Longer term outcomes from a randomised trial of prescribing strategies in otitis media. Br J Gen Pract (2006) 0.94
Has UK guidance affected general practitioner antibiotic prescribing for otitis media in children? J Public Health (Oxf) (2008) 0.91
Antimicrobial resistance in the nasopharyngeal flora of children with acute otitis media and otitis media recurring after amoxicillin therapy. J Med Microbiol (2005) 0.87
2013 ESH/ESC guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J (2013) 12.73
2013 ESC guidelines on the management of stable coronary artery disease: the Task Force on the management of stable coronary artery disease of the European Society of Cardiology. Eur Heart J (2013) 9.54
Antibiotics for acute otitis media: a meta-analysis with individual patient data. Lancet (2006) 5.83
Respiratory syncytial virus and recurrent wheeze in healthy preterm infants. N Engl J Med (2013) 5.06
Clinical epidemiology of heart failure. Heart (2007) 4.11
Attributable mortality of ventilator-associated pneumonia: a meta-analysis of individual patient data from randomised prevention studies. Lancet Infect Dis (2013) 4.08
Otitis media. Lancet (2004) 3.71
Unrecognized heart failure in elderly patients with stable chronic obstructive pulmonary disease. Eur Heart J (2005) 3.58
B-type natriuretic peptide and prognosis in heart failure patients with preserved and reduced ejection fraction. J Am Coll Cardiol (2013) 3.54
The Wells rule does not adequately rule out deep venous thrombosis in primary care patients. Ann Intern Med (2005) 3.21
Antibiotics for acute otitis media in children. Cochrane Database Syst Rev (2013) 3.15
Beta-blockers may reduce mortality and risk of exacerbations in patients with chronic obstructive pulmonary disease. Arch Intern Med (2010) 2.82
A trial of treatment for acute otorrhea in children with tympanostomy tubes. N Engl J Med (2014) 2.74
Burden of adhesions in abdominal and pelvic surgery: systematic review and met-analysis. BMJ (2013) 2.53
Safe exclusion of pulmonary embolism using the Wells rule and qualitative D-dimer testing in primary care: prospective cohort study. BMJ (2012) 2.38
Comparing the diagnostic performance of 2 clinical decision rules to rule out deep vein thrombosis in primary care patients. Ann Fam Med (2011) 2.34
Effect of moderate or intensive disease management program on outcome in patients with heart failure: Coordinating Study Evaluating Outcomes of Advising and Counseling in Heart Failure (COACH). Arch Intern Med (2008) 2.23
No evidence for the diagnostic value of Borrelia serology in patients with sudden hearing loss. Otolaryngol Head Neck Surg (2012) 2.17
Safely ruling out deep venous thrombosis in primary care. Ann Intern Med (2009) 2.16
Grommets (ventilation tubes) for hearing loss associated with otitis media with effusion in children. Cochrane Database Syst Rev (2010) 2.14
Clinical evaluation of geriatric outpatients with suspected heart failure: value of symptoms, signs, and additional tests. Eur J Heart Fail (2011) 2.10
Tonsillectomy or adenotonsillectomy versus non-surgical management for obstructive sleep-disordered breathing in children. Cochrane Database Syst Rev (2015) 2.06
Effectiveness of trimethoprim/sulfamethoxazole for children with chronic active otitis media: a randomized, placebo-controlled trial. Pediatrics (2007) 2.06
Estimating measures of interaction on an additive scale for preventive exposures. Eur J Epidemiol (2011) 1.94
Estimating the attributable mortality of ventilator-associated pneumonia from randomized prevention studies. Crit Care Med (2011) 1.82
Ventilator-associated pneumonia and mortality: a systematic review of observational studies. Crit Care Med (2009) 1.81
Accuracy of multiparametric MRI for prostate cancer detection: a meta-analysis. AJR Am J Roentgenol (2014) 1.77
Limited value of patient history and physical examination in diagnosing deep vein thrombosis in primary care. Fam Pract (2005) 1.73
Antibiotics for acute otitis media in children. Cochrane Database Syst Rev (2015) 1.72
SYRCLE's risk of bias tool for animal studies. BMC Med Res Methodol (2014) 1.72
Chronic suppurative otitis media: a review. Int J Pediatr Otorhinolaryngol (2005) 1.70
Systemic corticosteroids for acute sinusitis. Cochrane Database Syst Rev (2014) 1.70
Pneumococcal conjugate vaccines for preventing otitis media. Cochrane Database Syst Rev (2014) 1.70
Heart failure and chronic obstructive pulmonary disease: An ignored combination? Eur J Heart Fail (2006) 1.68
Routine health insurance data for scientific research: potential and limitations of the Agis Health Database. J Clin Epidemiol (2011) 1.63
Differences between general practitioners and cardiologists in diagnosis and management of heart failure: a survey in every-day practice. Eur J Heart Fail (2003) 1.63
The diagnostic value of history and physical examination for COPD in suspected or known cases: a systematic review. Fam Pract (2009) 1.62
Exercise training in heart failure: from theory to practice. A consensus document of the Heart Failure Association and the European Association for Cardiovascular Prevention and Rehabilitation. Eur J Heart Fail (2011) 1.61
Adenotonsillectomy or watchful waiting in patients with mild to moderate symptoms of throat infections or adenotonsillar hypertrophy: a randomized comparison of costs and effects. Arch Otolaryngol Head Neck Surg (2007) 1.61
Effect of pneumococcal vaccination on quality of life in children with recurrent acute otitis media: a randomized, controlled trial. Pediatrics (2005) 1.59
Atopic disease and exhaled nitric oxide in an unselected population of young adults. Ann Allergy Asthma Immunol (2008) 1.52
Effect of a pharmacist-led intervention on diuretic compliance in heart failure patients: a randomized controlled study. J Card Fail (2003) 1.50
Predicting non-response to ranibizumab in patients with neovascular age-related macular degeneration. Ophthalmic Epidemiol (2014) 1.50
Lack of long-term effects of high-dose inhaled beclomethasone for respiratory syncytial virus bronchiolitis: a randomized placebo-controlled trial. Pediatr Infect Dis J (2014) 1.46
Heart-type fatty acid-binding protein in the early diagnosis of acute myocardial infarction: a systematic review and meta-analysis. Heart (2010) 1.45
Ruling out deep venous thrombosis in primary care. A simple diagnostic algorithm including D-dimer testing. Thromb Haemost (2005) 1.43
2016 European Guidelines on cardiovascular disease prevention in clinical practice. Rev Esp Cardiol (Engl Ed) (2016) 1.42
[Multidisciplinary guideline 'Heart failure 2010']. Ned Tijdschr Geneeskd (2011) 1.40
The furosemide diagnostic test in suspected slow-onset heart failure: popular but not useful. Eur J Heart Fail (2011) 1.39
No evidence for marked ethnic differences in accuracy of self-reported diabetes, hypertension, and hypercholesterolemia. J Clin Epidemiol (2007) 1.32
Penicillin for acute sore throat in children: randomised, double blind trial. BMJ (2003) 1.31
Systemic corticosteroid monotherapy for clinically diagnosed acute rhinosinusitis: a randomized controlled trial. CMAJ (2012) 1.28
Poor quality of reporting confounding bias in observational intervention studies: a systematic review. Ann Epidemiol (2008) 1.23
Incidence and determinants of moderate COPD (GOLD II) in male smokers aged 40-65 years: 5-year follow up. Br J Gen Pract (2006) 1.22
"GOLD or lower limit of normal definition? A comparison with expert-based diagnosis of chronic obstructive pulmonary disease in a prospective cohort-study". Respir Res (2012) 1.22
Chest radiography in general practice: indications, diagnostic yield and consequences for patient management. Br J Gen Pract (2006) 1.20
Early assessment of acute coronary syndromes in the emergency department: the potential diagnostic value of circulating microRNAs. EMBO Mol Med (2012) 1.20
Confounding of subgroup analyses in randomized data. Arch Intern Med (2009) 1.19
In-hospital cardiac arrest is associated with use of non-antiarrhythmic QTc-prolonging drugs. Br J Clin Pharmacol (2006) 1.19
Epidemiology, natural history, and risk factors: panel report from the Ninth International Research Conference on Otitis Media. Int J Pediatr Otorhinolaryngol (2009) 1.18
Factors influencing non-approval of new drugs in Europe. Nat Rev Drug Discov (2012) 1.18
The Utrecht Health Project: optimization of routine healthcare data for research. Eur J Epidemiol (2005) 1.17
International perspectives on management of acute otitis media: a qualitative review. Int J Pediatr Otorhinolaryngol (2004) 1.16
The diagnostic value of physical examination and additional testing in primary care patients with suspected heart failure. Circulation (2011) 1.16
Comparison of registered and published primary outcomes in randomized clinical trials of surgical interventions. Ann Surg (2013) 1.16
Added value of a physician-and-nurse-directed heart failure clinic: results from the Deventer-Alkmaar heart failure study. Heart (2006) 1.16
Prevalence of undetected persistent airflow obstruction in male smokers 40-65 years old. Fam Pract (2005) 1.15
2016 ESC/EAS Guidelines for the Management of Dyslipidaemias. Eur Heart J (2016) 1.14
Deep vein thrombosis in primary care: possible malignancy? Br J Gen Pract (2006) 1.12
Room for improvement in conducting and reporting non-inferiority randomized controlled trials on drugs: a systematic review. PLoS One (2010) 1.11
Advantages of the nested case-control design in diagnostic research. BMC Med Res Methodol (2008) 1.11
Open and closed endotracheal suction systems in mechanically ventilated intensive care patients: a meta-analysis. Crit Care Med (2007) 1.11
Antibiotics for otitis media with effusion in children. Cochrane Database Syst Rev (2012) 1.10
Accuracy and feasibility of daily infrared tympanic membrane temperature measurements in the identification of fever in children. Int J Pediatr Otorhinolaryngol (2003) 1.09
Comparison of methods of handling missing data in individual patient data meta-analyses: an empirical example on antibiotics in children with acute otitis media. Am J Epidemiol (2008) 1.08