Published in Pak J Biol Sci on April 01, 2009
The translesion DNA polymerase theta plays a dominant role in immunoglobulin gene somatic hypermutation. EMBO J (2005) 1.76
BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-κB pathway. Nat Commun (2012) 1.62
HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation. Nat Immunol (2009) 1.41
14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination. Nat Struct Mol Biol (2010) 1.41
Toll-like receptors and B-cell receptors synergize to induce immunoglobulin class-switch DNA recombination: relevance to microbial antibody responses. Crit Rev Immunol (2010) 1.22
Regulation of aicda expression and AID activity: relevance to somatic hypermutation and class switch DNA recombination. Crit Rev Immunol (2007) 1.19
Interleukin-1 receptor antagonist (IL-1Ra) and IL-1Ra producing mesenchymal stem cells as modulators of diabetogenesis. Autoimmunity (2010) 1.09
Enteric viruses in pediatric diarrhea in Saudi Arabia. J Med Virol (2008) 1.05
AID dysregulation in lupus-prone MRL/Fas(lpr/lpr) mice increases class switch DNA recombination and promotes interchromosomal c-Myc/IgH loci translocations: modulation by HoxC4. Autoimmunity (2011) 0.94
Evaluation of the relationship between follicular fluid oxidative stress, ovarian hormones, and response to gonadotropin stimulation. Fertil Steril (2007) 0.93
IL28B polymorphisms predict the virological response to standard therapy in patients with chronic hepatitis C virus genotype 4 infection. Hepatol Int (2013) 0.92
Induction of oxidative stress, DNA damage, and apoptosis in a malignant human skin melanoma cell line after exposure to zinc oxide nanoparticles. Int J Nanomedicine (2013) 0.92
Analysis of gene mutations involved in chloroquine resistance in Plasmodium falciparum parasites isolated from patients in the southwest of Saudi Arabia. Ann Saudi Med (2010) 0.90
Endonuclease G plays a role in immunoglobulin class switch DNA recombination by introducing double-strand breaks in switch regions. Mol Immunol (2010) 0.89
Arsenic trioxide-mediated oxidative stress and genotoxicity in human hepatocellular carcinoma cells. Onco Targets Ther (2013) 0.89
Rapid activation of FAK/mTOR/p70S6K/PAK1-signaling controls the early testosterone-induced actin reorganization in colon cancer cells. Cell Signal (2013) 0.88
Safety and efficacy of peginterferon-α2a plus ribavirin treatment in renal transplant recipients with chronic hepatitis C. J Hepatol (2013) 0.87
Iron oxide nanoparticles induce oxidative stress, DNA damage, and caspase activation in the human breast cancer cell line. Biol Trace Elem Res (2014) 0.87
Integrative and comparative genomics analysis of early hepatocellular carcinoma differentiated from liver regeneration in young and old. Mol Cancer (2010) 0.87
Source of drug resistant Plasmodium falciparum in a potential malaria elimination site in Saudi Arabia. Infect Genet Evol (2012) 0.83
Percutaneous obliteration of patent processus vaginalis: a rat model for future inguinal hernia repair in children. J Pediatr Surg (2013) 0.83
The bioactivity of human bone morphogenetic protein-15 is sensitive to C-terminal modification: characterization of the purified untagged processed mature region. Mol Cell Endocrinol (2010) 0.82
Human fetal testis Leydig cell disruption by exposure to the pesticide dieldrin at low concentrations. Hum Reprod (2007) 0.82
Distribution of drug resistance genotypes in Plasmodium falciparum in an area of limited parasite diversity in Saudi Arabia. Am J Trop Med Hyg (2012) 0.82
Differential effects of dehydroepiandrosterone and testosterone in prostate and colon cancer cell apoptosis: the role of nerve growth factor (NGF) receptors. Endocrinology (2013) 0.81
Membrane androgen receptor down-regulates c-src-activity and beta-catenin transcription and triggers GSK-3beta-phosphorylation in colon tumor cells. Cell Physiol Biochem (2014) 0.81
Editorial: Anti-Müllerian hormone: Cinderella finds new admirers. J Clin Endocrinol Metab (2006) 0.81
Inhibition of SGK1 enhances mAR-induced apoptosis in MCF-7 breast cancer cells. Cancer Biol Ther (2015) 0.79
The Role of RhoA, RhoB and RhoC GTPases in Cell Morphology, Proliferation and Migration in Human Cytomegalovirus (HCMV) Infected Glioblastoma Cells. Cell Physiol Biochem (2016) 0.79
Single nucleotide polymorphisms in CXCR1 gene and its association with hepatitis B infected patients in Saudi Arabia. Ann Hepatol (2013) 0.78
A steroidal Na+/K+ ATPase inhibitor triggers pro-apoptotic signaling and induces apoptosis in prostate and lung tumor cells. Anticancer Agents Med Chem (2014) 0.78
Relationship of interferon-γ-inducible protein-10 kDa with viral response in patients with various heterogeneities of hepatitis C virus genotype-4. Eur J Gastroenterol Hepatol (2013) 0.78
Testosterone induced apoptosis in colon cancer cells is regulated by PI3K/Rac1 signaling. Asian J Androl (2013) 0.77
Chorein Sensitive Dopamine Release from Pheochromocytoma (PC12) Cells. Neurosignals (2015) 0.76
Chorein Sensitive Arrangement of Cytoskeletal Architecture. Cell Physiol Biochem (2015) 0.76
Transmission of hepatitis-B virus through salivary blood group antigens in saliva. J Coll Physicians Surg Pak (2010) 0.76
RhoB is a component of the human cytomegalovirus assembly complex and is required for efficient viral production. Cell Cycle (2015) 0.76
Steroidal cardiac Na+/K+ ATPase inhibitors exhibit strong anti-cancer potential in vitro and in prostate and lung cancer xenografts in vivo. Anticancer Agents Med Chem (2014) 0.76
Chorein Sensitive Orai1 Expression and Store Operated Ca2+ Entry in Rhabdomyosarcoma Cells. Cell Physiol Biochem (2016) 0.76
Evaluation of Isolation Methods for Circulating Tumor Cells (CTCs). Cell Physiol Biochem (2016) 0.75
Blood chemical changes and renal histological alterations induced by gentamicin in rats. Saudi J Biol Sci (2011) 0.75
Developing species-specific primers to identify Bulinus truncatus and Bulinus beccari, the intermediate hosts of Schistosoma haematobium in Saudi Arabia. Gene (2012) 0.75
Detecting mutations in PfCRT and PfMDR1 genes among Plasmodium falciparum isolates from Saudi Arabia by pyrosequencing. Parasitol Res (2011) 0.75