| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Insight into 2-phenylpyrazolo[1,5-a]pyrimidin-3-yl acetamides as peripheral benzodiazepine receptor ligands: synthesis, biological evaluation and 3D-QSAR investigation.
|
Bioorg Med Chem
|
2005
|
1.26
|
|
2
|
New fluoro derivatives of the pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide system: evaluation of fluorine binding properties in the benzodiazepine site on γ-aminobutyrric acid type A (GABA(A)) receptor. Design, synthesis, biological, and molecular modeling investigation.
|
J Med Chem
|
2010
|
0.90
|
|
3
|
Enhancement of viniferin production in Vitis vinifera L. cv. Alphonse Lavallée Cell suspensions by low-energy ultrasound alone and in combination with methyl jasmonate.
|
J Agric Food Chem
|
2012
|
0.81
|
|
4
|
Novel 3-aroylpyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides 8-substituted, ligands at GABAA/benzodiazepine receptor complex: synthesis, pharmacological and molecular modeling studies.
|
Bioorg Med Chem
|
2008
|
0.79
|
|
5
|
GRIND-derived pharmacophore model for a series of alpha-tropanyl derivative ligands of the sigma-2 receptor.
|
J Comput Aided Mol Des
|
2004
|
0.79
|
|
6
|
Searching for a reliable orientation of ligands in their binding site: comparison between a structure-based (Glide) and a ligand-based (FIGO) approach in the case study of PDE4 inhibitors.
|
J Med Chem
|
2005
|
0.77
|
|
7
|
Synthesis, SAR and in vitro evaluation of new cyclic Arg-Gly-Asp pseudopentapeptides containing a s-cis peptide bond as integrin alphavbeta3 and alphavbeta5 ligands.
|
Bioorg Med Chem
|
2008
|
0.76
|
|
8
|
Synthesis, in vivo evaluation, and molecular modeling studies of new pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide derivatives. Identification of a bifunctional hydrogen bond area related to the inverse agonism.
|
J Med Chem
|
2009
|
0.76
|
|
9
|
Modeling and biological investigations of an unusual behavior of novel synthesized acridine-based polyamine ligands in the binding of double helix and G-quadruplex DNA.
|
ChemMedChem
|
2010
|
0.76
|
|
10
|
New 3-, 8-disubstituted pyrazolo[5,1-c][1,2,4]benzotriazines useful for studying the interaction with the HBp-3 area (hydrogen bond point area) in the benzodiazepine site on the γ-aminobutyric acid type A (GABAA) receptor.
|
Bioorg Med Chem
|
2011
|
0.75
|
|
11
|
Design and solid phase synthesis of new DOTA conjugated (+)-biotin dimers planned to develop molecular weight-tuned avidin oligomers.
|
Org Biomol Chem
|
2015
|
0.75
|