PubRank

Daniel A Portnoy

Author PubWeight™ 89.75‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9. Nat Immunol 2006 5.83
2 c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response. Science 2010 5.31
3 Construction, characterization, and use of two Listeria monocytogenes site-specific phage integration vectors. J Bacteriol 2002 4.75
4 Mice lacking the type I interferon receptor are resistant to Listeria monocytogenes. J Exp Med 2004 3.94
5 The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides. Infect Immun 2010 3.89
6 Patterns of pathogenesis: discrimination of pathogenic and nonpathogenic microbes by the innate immune system. Cell Host Microbe 2009 3.86
7 Innate recognition of bacteria by a macrophage cytosolic surveillance pathway. Proc Natl Acad Sci U S A 2002 3.85
8 Listeria monocytogenes triggers AIM2-mediated pyroptosis upon infrequent bacteriolysis in the macrophage cytosol. Cell Host Microbe 2010 3.09
9 Distinct TLR- and NLR-mediated transcriptional responses to an intracellular pathogen. PLoS Pathog 2008 2.86
10 Listeriolysin O: a phagosome-specific lysin. Microbes Infect 2007 2.50
11 Mycobacterium tuberculosis activates the DNA-dependent cytosolic surveillance pathway within macrophages. Cell Host Microbe 2012 2.39
12 The Listeria monocytogenes hemolysin has an acidic pH optimum to compartmentalize activity and prevent damage to infected host cells. J Cell Biol 2002 2.29
13 Listeria-based cancer vaccines that segregate immunogenicity from toxicity. Proc Natl Acad Sci U S A 2004 2.27
14 SecA2-dependent secretion of autolytic enzymes promotes Listeria monocytogenes pathogenesis. Proc Natl Acad Sci U S A 2003 2.18
15 A specific gene expression program triggered by Gram-positive bacteria in the cytosol. Proc Natl Acad Sci U S A 2004 2.10
16 Bacterial ligands generated in a phagosome are targets of the cytosolic innate immune system. PLoS Pathog 2007 1.93
17 The host cytosol: front-line or home front? Trends Microbiol 2002 1.66
18 Use of RNA interference in Drosophila S2 cells to identify host pathways controlling compartmentalization of an intracellular pathogen. Proc Natl Acad Sci U S A 2005 1.65
19 Listeria monocytogenes multidrug resistance transporters activate a cytosolic surveillance pathway of innate immunity. Proc Natl Acad Sci U S A 2008 1.63
20 Listeria monocytogenes mutants that fail to compartmentalize listerolysin O activity are cytotoxic, avirulent, and unable to evade host extracellular defenses. Infect Immun 2003 1.61
21 Identification of a second Listeria secA gene associated with protein secretion and the rough phenotype. Mol Microbiol 2002 1.57
22 Drosophila S2 cells: an alternative infection model for Listeria monocytogenes. Cell Microbiol 2003 1.57
23 Listeria intracellular growth and virulence require host-derived lipoic acid. Science 2003 1.50
24 Cyclic di-AMP is critical for Listeria monocytogenes growth, cell wall homeostasis, and establishment of infection. MBio 2013 1.44
25 Listeria monocytogenes traffics from maternal organs to the placenta and back. PLoS Pathog 2006 1.40
26 Listeria monocytogenes engineered to activate the Nlrc4 inflammasome are severely attenuated and are poor inducers of protective immunity. Proc Natl Acad Sci U S A 2011 1.37
27 Listeriosis in the pregnant guinea pig: a model of vertical transmission. Infect Immun 2004 1.35
28 Inducible control of virulence gene expression in Listeria monocytogenes: temporal requirement of listeriolysin O during intracellular infection. J Bacteriol 2002 1.31
29 Development of a mariner-based transposon and identification of Listeria monocytogenes determinants, including the peptidyl-prolyl isomerase PrsA2, that contribute to its hemolytic phenotype. J Bacteriol 2009 1.31
30 Comparison of widely used Listeria monocytogenes strains EGD, 10403S, and EGD-e highlights genomic variations underlying differences in pathogenicity. MBio 2014 1.29
31 Cytosolic entry controls CD8+-T-cell potency during bacterial infection. Infect Immun 2006 1.29
32 Phosphorylation, ubiquitination and degradation of listeriolysin O in mammalian cells: role of the PEST-like sequence. Cell Microbiol 2006 1.28
33 Ena/VASP proteins contribute to Listeria monocytogenes pathogenesis by controlling temporal and spatial persistence of bacterial actin-based motility. Mol Microbiol 2003 1.20
34 Innate immune pathways triggered by Listeria monocytogenes and their role in the induction of cell-mediated immunity. Adv Immunol 2012 1.17
35 Dynamic imaging of the effector immune response to listeria infection in vivo. PLoS Pathog 2011 1.16
36 Growth of Listeria monocytogenes in the guinea pig placenta and role of cell-to-cell spread in fetal infection. J Infect Dis 2005 1.16
37 Listeriolysin O secreted by Listeria monocytogenes into the host cell cytosol is degraded by the N-end rule pathway. Infect Immun 2007 1.07
38 Hyperinduction of host beta interferon by a Listeria monocytogenes strain naturally overexpressing the multidrug efflux pump MdrT. Infect Immun 2012 1.06
39 Oral infection with signature-tagged Listeria monocytogenes reveals organ-specific growth and dissemination routes in guinea pigs. Infect Immun 2011 1.04
40 Mutations of the Listeria monocytogenes peptidoglycan N-deacetylase and O-acetylase result in enhanced lysozyme sensitivity, bacteriolysis, and hyperinduction of innate immune pathways. Infect Immun 2011 0.98
41 Activation of immature hepatic NK cells as immunotherapy for liver metastatic disease. J Immunol 2007 0.94
42 Suppression of cell-mediated immunity following recognition of phagosome-confined bacteria. PLoS Pathog 2009 0.93
43 Killed but metabolically active Bacillus anthracis vaccines induce broad and protective immunity against anthrax. Infect Immun 2009 0.87
44 Posttranslocation chaperone PrsA2 regulates the maturation and secretion of Listeria monocytogenes proprotein virulence factors. J Bacteriol 2011 0.83
45 Listeria monocytogenes 6-Phosphogluconolactonase mutants induce increased activation of a host cytosolic surveillance pathway. Infect Immun 2009 0.81
46 Development of a single-gene, signature-tag-based approach in combination with alanine mutagenesis to identify listeriolysin O residues critical for the in vivo survival of Listeria monocytogenes. Infect Immun 2012 0.79
47 A bacterial pore-forming toxin forms aggregates in cells that resemble those associated with neurodegenerative diseases. Cell Microbiol 2007 0.78
48 Strategies Used by Bacteria to Grow in Macrophages. Microbiol Spectr 2016 0.75
49 Microbial pathogenesis and the eukaryotic cytoskeleton at the American Society for Cell Biology annual meeting. Cell Microbiol 2002 0.75