J B Flanegan

Author PubWeight™ 61.94‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Covalent linkage of a protein to a defined nucleotide sequence at the 5'-terminus of virion and replicative intermediate RNAs of poliovirus. Proc Natl Acad Sci U S A 1977 8.12
2 Poliovirus-specific primer-dependent RNA polymerase able to copy poly(A). Proc Natl Acad Sci U S A 1977 3.69
3 Identification of poliovirus polypeptide P63 as a soluble RNA-dependent RNA polymerase. J Virol 1980 3.26
4 Poliovirus polyuridylic acid polymerase and RNA replicase have the same viral polypeptide. J Virol 1979 3.12
5 5'-Terminal nucleotide sequences of polio virus polyribosomal RNA and virion RNA are identical. Nature 1977 3.00
6 Complete replication of poliovirus in vitro: preinitiation RNA replication complexes require soluble cellular factors for the synthesis of VPg-linked RNA. J Virol 1995 2.67
7 5' cloverleaf in poliovirus RNA is a cis-acting replication element required for negative-strand synthesis. EMBO J 2001 2.67
8 Coupled translation and replication of poliovirus RNA in vitro: synthesis of functional 3D polymerase and infectious virus. J Virol 1993 2.38
9 Isolation of a soluble and template-dependent poliovirus RNA polymerase that copies virion RNA in vitro. J Virol 1979 2.21
10 Poliovirus RNA-dependent RNA polymerase and host cell protein synthesize product RNA twice the size of poliovirion RNA in vitro. J Virol 1985 2.11
11 Synchronous replication of poliovirus RNA: initiation of negative-strand RNA synthesis requires the guanidine-inhibited activity of protein 2C. J Virol 1997 2.04
12 Translating ribosomes inhibit poliovirus negative-strand RNA synthesis. J Virol 1999 2.03
13 Genome-length copies of poliovirion RNA are synthesized in vitro by the poliovirus RNA-dependent RNA polymerase. J Biol Chem 1982 2.02
14 Direct measurement of the poliovirus RNA polymerase error frequency in vitro. J Virol 1988 1.99
15 Replication of poliovirus RNA and subgenomic RNA transcripts in transfected cells. J Virol 1992 1.88
16 Assays for poliovirus polymerase, 3D(Pol), and authentic RNA replication in HeLa S10 extracts. Methods Enzymol 1996 1.67
17 Self-catalyzed linkage of poliovirus terminal protein VPg to poliovirus RNA. Cell 1989 1.63
18 Determination of the poliovirus RNA polymerase error frequency at eight sites in the viral genome. J Virol 1992 1.61
19 Poliovirus RNA-dependent RNA polymerase synthesizes full-length copies of poliovirion RNA, cellular mRNA, and several plant virus RNAs in vitro. J Virol 1982 1.46
20 A point mutation in the poliovirus polymerase gene determines a complementable temperature-sensitive defect of RNA replication. Virology 1989 1.32
21 Anti-VPg antibody precipitation of product RNA synthesized in vitro by the poliovirus polymerase and host factor is mediated by VPg on the poliovirion RNA template. J Virol 1986 1.15
22 Poliovirus RNA recombination in cell-free extracts. RNA 1997 1.11
23 Measurement of poliovirus RNA polymerase binding to poliovirion and nonviral RNAs using a filter-binding assay. Nucleic Acids Res 1988 1.11
24 Regulation of deoxyribonucleotide biosynthesis during in vivo bacteriophage T4 DNA replication. Intrinsic control of synthesis of thymine and 5-hydroxymethylcytosine deoxyribonucleotides at precise ratio found in DNA. J Biol Chem 1977 1.09
25 A conserved base pair within helix P4 of the Tetrahymena ribozyme helps to form the tertiary structure required for self-splicing. EMBO J 1989 1.08
26 Interference with vaccinia virus growth caused by insertion of the coding sequence for poliovirus protease 2A. Virology 1989 0.96
27 Measurement of temperature within the sample cell during sedimentation velocity experiments. Anal Biochem 1971 0.94
28 Poliovirus RNA polymerase mutation 3D-M394T results in a temperature-sensitive defect in RNA synthesis. Virology 1996 0.86
29 Characterization of product RNAs synthesized in vitro by poliovirus RNA polymerase purified by chromatography on hydroxylapatite or poly(U) Sepharose. J Virol 1987 0.82
30 Noncovalent interactions in viruses: characterization of their role in the pH and thermally induced conformational changes in bromegrass mosaic virus. Virology 1973 0.80
31 Role of deoxycytidylate deaminase in deoxyribonucleotide synthesis in bacteriophage T4 DNA replication. J Biol Chem 1977 0.77
32 Inhibitory effect of agents altering the structure of DNA on the synthesis of pyrimidine deoxyribonucleotides in bacteriophage T4 DNA replication. J Biol Chem 1977 0.77