Obesity potentiates the growth and dissemination of pancreatic cancer.

Survival among patients with pancreatic cancer and long-standing or recent-onset diabetes mellitus. J Clin Oncol (2014) 2.21

Obesity-Induced Inflammation and Desmoplasia Promote Pancreatic Cancer Progression and Resistance to Chemotherapy. Cancer Discov (2016) 2.16

The role of adiponectin in cancer: a review of current evidence. Endocr Rev (2012) 1.78

A prospective study of plasma adiponectin and pancreatic cancer risk in five US cohorts. J Natl Cancer Inst (2012) 1.74

Novel immunocompetent murine models representing advanced local and metastatic pancreatic cancer. J Surg Res (2011) 1.54

Famine versus feast: understanding the metabolism of tumors in vivo. Trends Biochem Sci (2015) 1.42

Molecular pathways: adiponectin and leptin signaling in cancer. Clin Cancer Res (2013) 1.37

Obesity adversely affects survival in pancreatic cancer patients. Cancer (2010) 1.28

Obesity and pancreatic cancer: overview of epidemiologic evidence and biologic mechanisms. Mol Carcinog (2012) 1.26

New strategies in pancreatic cancer: emerging epidemiologic and therapeutic concepts. Clin Cancer Res (2010) 1.25

Excess body weight and obesity--the link with gastrointestinal and hepatobiliary cancer. Nat Rev Gastroenterol Hepatol (2011) 1.18

Mechanisms of obesity-induced gastrointestinal neoplasia. Gastroenterology (2013) 1.18

The clinical significance of pancreatic steatosis. Nat Rev Gastroenterol Hepatol (2011) 1.10

Prediagnostic body mass index and pancreatic cancer survival. J Clin Oncol (2013) 1.08

Alternative origins of stroma in normal organs and disease. Stem Cell Res (2011) 0.94

PlGF/VEGFR-1 Signaling Promotes Macrophage Polarization and Accelerated Tumor Progression in Obesity. Clin Cancer Res (2016) 0.91

Deploying mouse models of pancreatic cancer for chemoprevention studies. Cancer Prev Res (Phila) (2010) 0.89

Obesity accelerates Helicobacter felis-induced gastric carcinogenesis by enhancing immature myeloid cell trafficking and TH17 response. Gut (2013) 0.89

Preoperative computed tomography measurements of pancreatic steatosis and visceral fat: prognostic markers for dissemination and lethality of pancreatic adenocarcinoma. HPB (Oxford) (2011) 0.88

Dietary energy balance modulation of Kras- and Ink4a/Arf+/--driven pancreatic cancer: the role of insulin-like growth factor-I. Cancer Prev Res (Phila) (2013) 0.85

Diet-induced obesity potentiates the growth of gastric cancer in mice. Exp Ther Med (2012) 0.85

Experimental animal models of pancreatic carcinogenesis for prevention studies and their relevance to human disease. Cancers (Basel) (2011) 0.84

Drugging the addict: non-oncogene addiction as a target for cancer therapy. EMBO Rep (2016) 0.84

Obesity and Cancer: An Angiogenic and Inflammatory Link. Microcirculation (2016) 0.84

Cholecystokinin mediates progression and metastasis of pancreatic cancer associated with dietary fat. Dig Dis Sci (2014) 0.83

Glucose metabolism gene variants modulate the risk of pancreatic cancer. Cancer Prev Res (Phila) (2011) 0.81

Recent advances and limitations of surgical treatment for pancreatic cancer. World J Clin Oncol (2011) 0.80

Adipocytes enhance murine pancreatic cancer growth via a hepatocyte growth factor (HGF)-mediated mechanism. Int J Surg (2016) 0.78

Modulation of the leptin receptor mediates tumor growth and migration of pancreatic cancer cells. PLoS One (2015) 0.77

Expression of the adipocytokine resistin and its association with the clinicopathological features and prognosis of pancreatic ductal adenocarcinoma. Oncol Lett (2012) 0.77

Robust Early Inflammation of the Peripancreatic Visceral Adipose Tissue During Diet-Induced Obesity in the KrasG12D Model of Pancreatic Cancer. Pancreas (2016) 0.76

Adipocytes promote pancreatic cancer cell proliferation via glutamine transfer. Biochem Biophys Rep (2016) 0.76

Glycemic index, glycemic load, and the risk of pancreatic cancer among postmenopausal women in the women's health initiative observational study and clinical trial. Cancer Causes Control (2010) 0.76

Leptin-Notch signaling axis is involved in pancreatic cancer progression. Oncotarget (2017) 0.75

Obesity and pancreatic cancer: possible role of the PI3K/Akt pathway. Surgery (2010) 0.75

Dietary factors modulate Helicobacter-associated gastric cancer in rodent models. Toxicol Pathol (2013) 0.75

Response to "Obesity potentiates the growth and dissemination of pancreatic cancer". Surgery (2010) 0.75

CD44+/CD24- breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis. Breast Cancer Res (2006) 6.35

NF-kappaB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4. J Biol Chem (2003) 3.98

Cystic pancreatic neoplasms: observe or operate. Ann Surg (2004) 3.68

Gallbladder cancer: the role of laparoscopy and radical resection. Ann Surg (2007) 3.38

Prognostic impact of ALDH1 in breast cancer: a story of stem cells and tumor microenvironment. Breast Cancer Res Treat (2009) 2.85

Surgical management of bile duct injuries sustained during laparoscopic cholecystectomy: perioperative results in 200 patients. Ann Surg (2005) 2.58

Neuroendocrine hepatic metastases: does aggressive management improve survival? Ann Surg (2005) 2.27

Estradiol-regulated microRNAs control estradiol response in breast cancer cells. Nucleic Acids Res (2009) 2.27

TG13 antimicrobial therapy for acute cholangitis and cholecystitis. J Hepatobiliary Pancreat Sci (2013) 2.23

FOXA1 expression in breast cancer--correlation with luminal subtype A and survival. Clin Cancer Res (2007) 2.22

Intraductal papillary mucinous neoplasms: predictors of malignant and invasive pathology. Ann Surg (2007) 2.10

TG13 diagnostic criteria and severity grading of acute cholecystitis (with videos). J Hepatobiliary Pancreat Sci (2013) 1.84

TG13 flowchart for the management of acute cholangitis and cholecystitis. J Hepatobiliary Pancreat Sci (2013) 1.82

Effect of hospital volume, surgeon experience, and surgeon volume on patient outcomes after pancreaticoduodenectomy: a single-institution experience. Arch Surg (2010) 1.72

Improved survival in resected biliary malignancies. Surgery (2002) 1.67

TG13 guidelines for diagnosis and severity grading of acute cholangitis (with videos). J Hepatobiliary Pancreat Sci (2013) 1.66

Background: Tokyo Guidelines for the management of acute cholangitis and cholecystitis. J Hepatobiliary Pancreat Surg (2007) 1.64

Fatty pancreas: a factor in postoperative pancreatic fistula. Ann Surg (2007) 1.62

Pancreatectomy risk calculator: an ACS-NSQIP resource. HPB (Oxford) (2010) 1.61

Diagnostic criteria and severity assessment of acute cholangitis: Tokyo Guidelines. J Hepatobiliary Pancreat Surg (2007) 1.58

Annular pancreas in adults. AJR Am J Roentgenol (2009) 1.57

SLUG/SNAI2 and tumor necrosis factor generate breast cells with CD44+/CD24- phenotype. BMC Cancer (2010) 1.56

TG13: Updated Tokyo Guidelines for the management of acute cholangitis and cholecystitis. J Hepatobiliary Pancreat Sci (2013) 1.53

Nuclear factor-kappaB is constitutively activated in prostate cancer in vitro and is overexpressed in prostatic intraepithelial neoplasia and adenocarcinoma of the prostate. Clin Cancer Res (2004) 1.53

New diagnostic criteria and severity assessment of acute cholecystitis in revised Tokyo Guidelines. J Hepatobiliary Pancreat Sci (2012) 1.49

Surgical treatment of patients with acute cholecystitis: Tokyo Guidelines. J Hepatobiliary Pancreat Surg (2007) 1.49

Robotic distal pancreatectomy: cost effective? Surgery (2010) 1.47

Nonalcoholic fatty pancreas disease. HPB (Oxford) (2007) 1.44

ITF2 is a target of CXCR4 in MDA-MB-231 breast cancer cells and is associated with reduced survival in estrogen receptor-negative breast cancer. Cancer Biol Ther (2010) 1.44

Flowcharts for the diagnosis and treatment of acute cholangitis and cholecystitis: Tokyo Guidelines. J Hepatobiliary Pancreat Surg (2007) 1.43

Effect of hyperbaric oxygen therapy on patients with herpes zoster. Undersea Hyperb Med (2013) 1.42

Surgical treatment of choledochal cysts. J Hepatobiliary Pancreat Surg (2003) 1.40

TG13 surgical management of acute cholecystitis. J Hepatobiliary Pancreat Sci (2013) 1.39

Epithelial-to-mesenchymal transition and ovarian tumor progression induced by tissue transglutaminase. Cancer Res (2009) 1.39

Cystic pancreatic neoplasms: enucleate or resect? J Gastrointest Surg (2003) 1.37

CT vs MRCP: optimal classification of IPMN type and extent. J Gastrointest Surg (2007) 1.34

The sesquiterpene lactone parthenolide in combination with docetaxel reduces metastasis and improves survival in a xenograft model of breast cancer. Mol Cancer Ther (2005) 1.33

Results of the Tokyo Consensus Meeting Tokyo Guidelines. J Hepatobiliary Pancreat Surg (2007) 1.32

Gallstones: genetics versus environment. Ann Surg (2002) 1.32

Identity profiling of cell surface markers by multiplex gold nanorod probes. Nano Lett (2007) 1.30

Enhanced peritoneal ovarian tumor dissemination by tissue transglutaminase. Cancer Res (2007) 1.29

Does type of pancreaticojejunostomy after pancreaticoduodenectomy decrease rate of pancreatic fistula? A randomized, prospective, dual-institution trial. J Am Coll Surg (2009) 1.29

PROGgene: gene expression based survival analysis web application for multiple cancers. J Clin Bioinforma (2013) 1.28

Tissue transglutaminase protects epithelial ovarian cancer cells from cisplatin-induced apoptosis by promoting cell survival signaling. Carcinogenesis (2008) 1.24

New diagnostic criteria and severity assessment of acute cholangitis in revised Tokyo Guidelines. J Hepatobiliary Pancreat Sci (2012) 1.23

Effects of HIV protease inhibitor ritonavir on Akt-regulated cell proliferation in breast cancer. Clin Cancer Res (2006) 1.23

AKT alters genome-wide estrogen receptor alpha binding and impacts estrogen signaling in breast cancer. Mol Cell Biol (2008) 1.21

Breast-cancer stem cells-beyond semantics. Lancet Oncol (2012) 1.21

Annular pancreas: dramatic differences between children and adults. J Am Coll Surg (2008) 1.21

Antimicrobial therapy for acute cholangitis: Tokyo Guidelines. J Hepatobiliary Pancreat Surg (2007) 1.19

Cystic pancreatic neuroendocrine tumors: is preoperative diagnosis possible? J Gastrointest Surg (2002) 1.19

Methods and timing of biliary drainage for acute cholangitis: Tokyo Guidelines. J Hepatobiliary Pancreat Surg (2007) 1.19

Efficient system-wide coordination in noisy environments. Proc Natl Acad Sci U S A (2004) 1.18

Pancreatic steatosis promotes dissemination and lethality of pancreatic cancer. J Am Coll Surg (2009) 1.18

FOXA1 is an independent prognostic marker for ER-positive breast cancer. Breast Cancer Res Treat (2011) 1.17

Phosphoinositol phosphatase SHIP2 promotes cancer development and metastasis coupled with alterations in EGF receptor turnover. Carcinogenesis (2007) 1.16

Total pancreatectomy (R0 resection) improves survival over subtotal pancreatectomy in isolated neck margin positive pancreatic adenocarcinoma. Surgery (2007) 1.16

The p160 family coactivators regulate breast cancer cell proliferation and invasion through autocrine/paracrine activity of SDF-1alpha/CXCL12. Carcinogenesis (2005) 1.16

Parthenolide and sulindac cooperate to mediate growth suppression and inhibit the nuclear factor-kappa B pathway in pancreatic carcinoma cells. Mol Cancer Ther (2005) 1.16

Risk of morbidity and mortality following hepato-pancreato-biliary surgery. J Gastrointest Surg (2012) 1.16

Role of EUS for preoperative evaluation of cholangiocarcinoma: a large single-center experience. Gastrointest Endosc (2010) 1.15

A murine model of obesity implicates the adipokine milieu in the pathogenesis of severe acute pancreatitis. Am J Physiol Gastrointest Liver Physiol (2008) 1.14

Chemoembolization in patients at high risk: results and complications. J Vasc Interv Radiol (2006) 1.13

The platelet-derived growth factor receptor alpha is destabilized by geldanamycins in cancer cells. J Biol Chem (2006) 1.13

Improved outcomes in postoperative and pancreatitis-related visceral pseudoaneurysms. J Gastrointest Surg (2007) 1.13

Small pancreatic and periampullary neuroendocrine tumors: resect or enucleate? J Gastrointest Surg (2009) 1.10

TG13 current terminology, etiology, and epidemiology of acute cholangitis and cholecystitis. J Hepatobiliary Pancreat Sci (2013) 1.09

Phase I dose escalation trial of feverfew with standardized doses of parthenolide in patients with cancer. Invest New Drugs (2004) 1.09

Inhibiting proteasomal proteolysis sustains estrogen receptor-alpha activation. Mol Endocrinol (2004) 1.09

Role of AKT isotypes in breast cancer. J Pathol (2013) 1.07

High-level expression of forkhead-box protein A1 in metastatic prostate cancer. Histopathology (2011) 1.07

PROGgeneV2: enhancements on the existing database. BMC Cancer (2014) 1.07

Persistent upregulation of U6:SNORD44 small RNA ratio in the serum of breast cancer patients. Breast Cancer Res (2011) 1.05

Bax is required for resection-induced changes in apoptosis, proliferation, and members of the extrinsic cell death pathways. Gastroenterology (2004) 1.05

Surgical management of pancreatic cancer. Oncology (Williston Park) (2002) 1.05

HOXB13 mediates tamoxifen resistance and invasiveness in human breast cancer by suppressing ERα and inducing IL-6 expression. Cancer Res (2013) 1.05

Thymidylate synthase expression predicts the response to 5-fluorouracil-based adjuvant therapy in pancreatic cancer. Clin Cancer Res (2003) 1.05

Peri-operative blood transfusion and operative time are quality indicators for pancreatoduodenectomy. HPB (Oxford) (2010) 1.04

Declining morbidity and mortality rates in the surgical management of pancreatic necrosis. J Gastrointest Surg (2007) 1.04

Identification of signal transduction pathways involved in constitutive NF-kappaB activation in breast cancer cells. Oncogene (2002) 1.03

Factors associated with delayed gastric emptying after pancreaticoduodenectomy. HPB (Oxford) (2013) 1.02

Hepatic neuroendocrine metastases: chemo- or bland embolization? J Gastrointest Surg (2008) 1.02

ANTXR1, a stem cell-enriched functional biomarker, connects collagen signaling to cancer stem-like cells and metastasis in breast cancer. Cancer Res (2013) 1.00

Insulin resistance causes human gallbladder dysmotility. J Gastrointest Surg (2006) 1.00

NF-kappaB inhibition in human hepatocellular carcinoma and its potential as adjunct to sorafenib based therapy. Cancer Lett (2009) 0.99

Subcellular localization of activated AKT in estrogen receptor- and progesterone receptor-expressing breast cancers: potential clinical implications. Am J Pathol (2010) 0.99

Choledochoceles: are they choledochal cysts? Ann Surg (2010) 0.99

Impact of preoperative endoscopic ultrasound-guided fine needle aspiration on postoperative recurrence and survival in cholangiocarcinoma patients. Endoscopy (2013) 0.98

Pancreatic cystic neuroendocrine tumors: preoperative diagnosis with endoscopic ultrasound and fine-needle immunocytology. J Gastrointest Surg (2007) 0.98

Pancreatic fistula following pancreaticoduodenectomy: clinical predictors and patient outcomes. HPB Surg (2009) 0.98

Suppression of pancreatic tumor growth by combination chemotherapy with sulindac and LC-1 is associated with cyclin D1 inhibition in vivo. Mol Cancer Ther (2007) 0.97

Need for criteria for the diagnosis and severity assessment of acute cholangitis and cholecystitis: Tokyo Guidelines. J Hepatobiliary Pancreat Surg (2007) 0.97

Post-operative morbidity results in decreased long-term survival after resection for hilar cholangiocarcinoma. HPB (Oxford) (2010) 0.97

Delivery of nanoparticles to brain metastases of breast cancer using a cellular Trojan horse. Cancer Nanotechnol (2012) 0.96

Expression of Forkhead-box protein A1, a marker of luminal A type breast cancer, parallels low Oncotype DX 21-gene recurrence scores. Mod Pathol (2009) 0.96

The macrophage inhibitory cytokine integrates AKT/PKB and MAP kinase signaling pathways in breast cancer cells. Carcinogenesis (2005) 0.95

Insulin, leptin, and tumoral adipocytes promote murine pancreatic cancer growth. J Gastrointest Surg (2010) 0.95