Published in Mol Microbiol on July 28, 2009
Biphasic control logic of HAMP domain signalling in the Escherichia coli serine chemoreceptor. Mol Microbiol (2011) 2.08
HAMP domain conformers that propagate opposite signals in bacterial chemoreceptors. PLoS Biol (2013) 1.60
Structure of concatenated HAMP domains provides a mechanism for signal transduction. Structure (2010) 1.58
HAMP domain structural determinants for signalling and sensory adaptation in Tsr, the Escherichia coli serine chemoreceptor. Mol Microbiol (2013) 1.57
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Mechanistic insights revealed by the crystal structure of a histidine kinase with signal transducer and sensor domains. PLoS Biol (2013) 1.35
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Probing bacterial transmembrane histidine kinase receptor-ligand interactions with natural and synthetic molecules. Proc Natl Acad Sci U S A (2010) 1.12
The S helix mediates signal transmission as a HAMP domain coiled-coil extension in the NarX nitrate sensor from Escherichia coli K-12. J Bacteriol (2009) 1.10
Cys-scanning disulfide crosslinking and bayesian modeling probe the transmembrane signaling mechanism of the histidine kinase, PhoQ. Structure (2014) 1.10
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The YfiBNR signal transduction mechanism reveals novel targets for the evolution of persistent Pseudomonas aeruginosa in cystic fibrosis airways. PLoS Pathog (2012) 1.07
The mobility of two kinase domains in the Escherichia coli chemoreceptor array varies with signalling state. Mol Microbiol (2013) 1.01
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Mutational analysis of the transmembrane helix 2-HAMP domain connection in the Escherichia coli aspartate chemoreceptor tar. J Bacteriol (2010) 0.95
Mechanism of bacterial signal transduction revealed by molecular dynamics of Tsr dimers and trimers of dimers in lipid vesicles. PLoS Comput Biol (2012) 0.92
HAMP domain-mediated signal transduction probed with a mycobacterial adenylyl cyclase as a reporter. J Biol Chem (2011) 0.92
An unorthodox sensory adaptation site in the Escherichia coli serine chemoreceptor. J Bacteriol (2013) 0.91
Mechanistic insight into the conserved allosteric regulation of periplasmic proteolysis by the signaling molecule cyclic-di-GMP. Elife (2014) 0.91
Functional suppression of HAMP domain signaling defects in the E. coli serine chemoreceptor. J Mol Biol (2014) 0.91
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Mutational analysis of N381, a key trimer contact residue in Tsr, the Escherichia coli serine chemoreceptor. J Bacteriol (2011) 0.89
Thermosensing function of the Escherichia coli redox sensor Aer. J Bacteriol (2010) 0.87
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Architecture and signal transduction mechanism of the bacterial chemosensory array: progress, controversies, and challenges. Curr Opin Struct Biol (2014) 0.86
HAMP domain signal relay mechanism in a sensory rhodopsin-transducer complex. J Biol Chem (2012) 0.86
Different conformations of the kinase-on and kinase-off signaling states in the Aer HAMP domain. J Bacteriol (2011) 0.86
PAS/poly-HAMP signalling in Aer-2, a soluble haem-based sensor. Mol Microbiol (2010) 0.86
The S-helix determines the signal in a Tsr receptor/adenylyl cyclase reporter. J Biol Chem (2012) 0.85
Adenylate cyclase and the cyclic AMP receptor protein modulate stress resistance and virulence capacity of uropathogenic Escherichia coli. Infect Immun (2012) 0.85
Assembly of the transmembrane domain of E. coli PhoQ histidine kinase: implications for signal transduction from molecular simulations. PLoS Comput Biol (2013) 0.84
Structure, function, and on-off switching of a core unit contact between CheA kinase and CheW adaptor protein in the bacterial chemosensory array: A disulfide mapping and mutagenesis study. Biochemistry (2013) 0.84
Bacterial chemoreceptor dynamics correlate with activity state and are coupled over long distances. Proc Natl Acad Sci U S A (2015) 0.83
Hydrogen exchange mass spectrometry of functional membrane-bound chemotaxis receptor complexes. Biochemistry (2013) 0.83
Two distinct states of the HAMP domain from sensory rhodopsin transducer observed in unbiased molecular dynamics simulations. PLoS One (2013) 0.82
Hydrogen exchange differences between chemoreceptor signaling complexes localize to functionally important subdomains. Biochemistry (2014) 0.81
Salmonella chemoreceptors McpB and McpC mediate a repellent response to L-cystine: a potential mechanism to avoid oxidative conditions. Mol Microbiol (2012) 0.80
Elucidation of the multiple roles of CheD in Bacillus subtilis chemotaxis. Mol Microbiol (2012) 0.80
A Trigger Residue for Transmembrane Signaling in the Escherichia coli Serine Chemoreceptor. J Bacteriol (2015) 0.80
Phenol sensing by Escherichia coli chemoreceptors: a nonclassical mechanism. J Bacteriol (2011) 0.79
HAMP Domain Rotation and Tilting Movements Associated with Signal Transduction in the PhoQ Sensor Kinase. MBio (2015) 0.79
The HAMP signal relay domain adopts multiple conformational states through collective piston and tilt motions. PLoS Comput Biol (2013) 0.79
Delineating PAS-HAMP interaction surfaces and signalling-associated changes in the aerotaxis receptor Aer. Mol Microbiol (2016) 0.78
Structural characterization of AS1-membrane interactions from a subset of HAMP domains. Biochim Biophys Acta (2011) 0.78
Preformed Soluble Chemoreceptor Trimers That Mimic Cellular Assembly States and Activate CheA Autophosphorylation. Biochemistry (2015) 0.78
Differential repositioning of the second transmembrane helices from E. coli Tar and EnvZ upon moving the flanking aromatic residues. Biochim Biophys Acta (2014) 0.77
Differential role of HAMP-like linkers in regulating the functionality of the group III histidine kinase DhNik1p. J Biol Chem (2014) 0.77
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A mutational wrench in the HAMP gearbox. Mol Microbiol (2009) 0.77
Signaling and Adaptation Modulate the Dynamics of the Photosensoric Complex of Natronomonas pharaonis. PLoS Comput Biol (2015) 0.76
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Forcing the issue: aromatic tuning facilitates stimulus-independent modulation of a two-component signaling circuit. ACS Synth Biol (2014) 0.76
Chemotactic Signaling by Single-Chain Chemoreceptors. PLoS One (2015) 0.76
Evidence for a Helix-Clutch Mechanism of Transmembrane Signaling in a Bacterial Chemoreceptor. J Mol Biol (2016) 0.76
Differential backbone dynamics of companion helices in the extended helical coiled-coil domain of a bacterial chemoreceptor. Protein Sci (2015) 0.76
Molecular modeling of the HAMP domain of sensory rhodopsin II transducer from Natronomonas pharaonis. Biophysics (Nagoya-shi) (2010) 0.76
Coincidence detection and bi-directional transmembrane signaling control a bacterial second messenger receptor. Elife (2016) 0.75
Signaling Consequences of Structural Lesions that Alter the Stability of Chemoreceptor Trimers of Dimers. J Mol Biol (2017) 0.75
Mutational analysis of dimeric linkers in peri- and cytoplasmic domains of histidine kinase DctB reveals their functional roles in signal transduction. Open Biol (2014) 0.75
A tale of two machines: a review of the BLAST meeting, Tucson, AZ, 20-24 January 2013. Mol Microbiol (2013) 0.75
Lessons in Fundamental Mechanisms and Diverse Adaptations from the 2015 Bacterial Locomotion and Signal Transduction Meeting. J Bacteriol (2015) 0.75
Bacterial Chemoreceptor Dynamics: Helical Stability in the Cytoplasmic Domain Varies with Functional Segment and Adaptational Modification. J Mol Biol (2016) 0.75
Phenylpyrroles: 30 Years, Two Molecules and (Nearly) No Resistance. Front Microbiol (2016) 0.75
Stability and Conformation of a Chemoreceptor HAMP Domain Chimera Correlates with Signaling Properties. Biophys J (2017) 0.75
Employing aromatic tuning to modulate output from two-component signaling circuits. J Biol Eng (2015) 0.75
Paradoxical enhancement of chemoreceptor detection sensitivity by a sensory adaptation enzyme. Proc Natl Acad Sci U S A (2017) 0.75
Methyl-accepting chemotaxis proteins: a core sensing element in prokaryotes and archaea. Cell Mol Life Sci (2017) 0.75
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Bacterial chemoreceptors: high-performance signaling in networked arrays. Trends Biochem Sci (2007) 5.28
Collaborative signaling by mixed chemoreceptor teams in Escherichia coli. Proc Natl Acad Sci U S A (2002) 4.64
Crosslinking snapshots of bacterial chemoreceptor squads. Proc Natl Acad Sci U S A (2004) 3.09
Collaborative signaling by bacterial chemoreceptors. Curr Opin Microbiol (2005) 2.49
Insights into the organization and dynamics of bacterial chemoreceptor clusters through in vivo crosslinking studies. Proc Natl Acad Sci U S A (2005) 2.19
Biphasic control logic of HAMP domain signalling in the Escherichia coli serine chemoreceptor. Mol Microbiol (2011) 2.08
Mutational analysis of the connector segment in the HAMP domain of Tsr, the Escherichia coli serine chemoreceptor. J Bacteriol (2008) 1.59
Methylation-independent aerotaxis mediated by the Escherichia coli Aer protein. J Bacteriol (2004) 1.59
HAMP domain structural determinants for signalling and sensory adaptation in Tsr, the Escherichia coli serine chemoreceptor. Mol Microbiol (2013) 1.57
Loss- and gain-of-function mutations in the F1-HAMP region of the Escherichia coli aerotaxis transducer Aer. J Bacteriol (2006) 1.32
Conformational suppression of inter-receptor signaling defects. Proc Natl Acad Sci U S A (2006) 1.31
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Different signaling roles of two conserved residues in the cytoplasmic hairpin tip of Tsr, the Escherichia coli serine chemoreceptor. J Bacteriol (2008) 1.07
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The mobility of two kinase domains in the Escherichia coli chemoreceptor array varies with signalling state. Mol Microbiol (2013) 1.01
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Mutational analysis of the control cable that mediates transmembrane signaling in the Escherichia coli serine chemoreceptor. J Bacteriol (2011) 0.98
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Differential activation of Escherichia coli chemoreceptors by blue-light stimuli. J Bacteriol (2006) 0.96
An unorthodox sensory adaptation site in the Escherichia coli serine chemoreceptor. J Bacteriol (2013) 0.91
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Cross-linking evidence for motional constraints within chemoreceptor trimers of dimers. Biochemistry (2011) 0.86
Mutational analysis of the P1 phosphorylation domain in Escherichia coli CheA, the signaling kinase for chemotaxis. J Bacteriol (2013) 0.81
Signalling-dependent interactions between the kinase-coupling protein CheW and chemoreceptors in living cells. Mol Microbiol (2014) 0.80
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