Predicting clinical physiology: a Markov chain model of heart rate recovery after spontaneous breathing trials in mechanically ventilated patients.

Prediction of heart rate response to conclusion of the spontaneous breathing trial by fluctuation dissipation theory. Phys Biol (2013) 0.75

Invited Commentary for: Predicting clinical physiology: a Markov chain model of heart rate recovery after spontaneous breathing trials in mechanically ventilated patients. J Crit Care (2009) 0.75

High-frequency oscillatory ventilation for acute respiratory distress syndrome in adults: a randomized, controlled trial. Am J Respir Crit Care Med (2002) 3.43

Parallel tempering: theory, applications, and new perspectives. Phys Chem Chem Phys (2005) 3.39

Surgeons, intensivists, and the covenant of care: administrative models and values affecting care at the end of life--Updated. Crit Care Med (2003) 3.09

Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms. Nature (2004) 2.98

The emergence of modularity in biological systems. Phys Life Rev (2011) 2.93

Evolvability is a selectable trait. Proc Natl Acad Sci U S A (2004) 2.35

Inhibition of intestinal epithelial apoptosis and survival in a murine model of pneumonia-induced sepsis. JAMA (2002) 2.20

Overexpression of Bcl-2 in the intestinal epithelium improves survival in septic mice. Crit Care Med (2002) 2.20

Relationship between tracheostomy timing and duration of mechanical ventilation in critically ill patients. Crit Care Med (2005) 2.09

Quantifying influenza vaccine efficacy and antigenic distance. Vaccine (2006) 1.97

Sepsis from Pseudomonas aeruginosa pneumonia decreases intestinal proliferation and induces gut epithelial cell cycle arrest. Crit Care Med (2003) 1.83

Effects of age on mortality and antibiotic efficacy in cecal ligation and puncture. Shock (2003) 1.73

Targeted temperature management in critical care: a report and recommendations from five professional societies. Crit Care Med (2011) 1.72

Effects of aging on the immunopathologic response to sepsis. Crit Care Med (2009) 1.72

Antibiotics improve survival in sepsis independent of injury severity but do not change mortality in mice with markedly elevated interleukin 6 levels. Shock (2004) 1.68

Cancer causes increased mortality and is associated with altered apoptosis in murine sepsis. Crit Care Med (2010) 1.68

A meta-analysis of controlled trials of anticoagulant therapies in patients with sepsis. Shock (2003) 1.61

Tracheostomy protocol: experience with development and potential utility. Crit Care Med (2008) 1.56

High-dose exogenous iron following cecal ligation and puncture increases mortality rate in mice and is associated with an increase in gut epithelial and splenic apoptosis. Crit Care Med (2004) 1.54

Biologically variable ventilation improves gas exchange and respiratory mechanics in a model of severe bronchospasm. Crit Care Med (2007) 1.51

Multicenter implementation of a consensus-developed, evidence-based, spontaneous breathing trial protocol. Crit Care Med (2008) 1.51

Mechanisms of decreased intestinal epithelial proliferation and increased apoptosis in murine acute lung injury. Crit Care Med (2005) 1.49

Surgeons, intensivists, and the covenant of care: administrative models and values affecting care at the end of life. Crit Care Med (2003) 1.48

Physiological noise versus white noise to drive a variable ventilator in a porcine model of lung injury. Can J Anaesth (2008) 1.48

Prescribing patterns of hydrocortisone in septic shock: a single-center experience of how surviving sepsis guidelines are interpreted and translated into bedside practice. Crit Care Med (2013) 1.47

Effect of an education program on decreasing catheter-related bloodstream infections in the surgical intensive care unit. Crit Care Med (2002) 1.47

Treatment of hypophosphatemia using a protocol based on patient weight and serum phosphorus level in a surgical intensive care unit. J Am Coll Surg (2004) 1.45

Myocardial transcriptional profiles in a murine model of sepsis: evidence for the importance of age. Pediatr Crit Care Med (2008) 1.43

Genetic research and testing in critical care: surrogates' perspective. Crit Care Med (2006) 1.42

Examination of non-clinical factors affecting tracheostomy practice in an academic surgical intensive care unit. Crit Care Med (2009) 1.42

In silico screening of carbon-capture materials. Nat Mater (2012) 1.39

Epitope analysis for influenza vaccine design. Vaccine (2005) 1.39

The relationship between the surgeon and the intensivist in the surgical intensive care unit. Surg Clin North Am (2006) 1.32

Neutrophil depletion causes a fatal defect in murine pulmonary Staphylococcus aureus clearance. J Surg Res (2008) 1.30

Spontaneous emergence of modularity in a model of evolving individuals. Phys Rev Lett (2007) 1.28

Early antibiotic administration but not antibody therapy directed against IL-6 improves survival in septic mice predicted to die on basis of high IL-6 levels. Am J Physiol Regul Integr Comp Physiol (2005) 1.24

Structure and response in the world trade network. Phys Rev Lett (2010) 1.24

Enterocyte-specific epidermal growth factor prevents barrier dysfunction and improves mortality in murine peritonitis. Am J Physiol Gastrointest Liver Physiol (2009) 1.23

Plasticity of the systemic inflammatory response to acute infection during critical illness: development of the riboleukogram. PLoS One (2008) 1.19

Epidermal growth factor treatment decreases mortality and is associated with improved gut integrity in sepsis. Shock (2008) 1.16

CD4+ lymphocytes control gut epithelial apoptosis and mediate survival in sepsis. FASEB J (2009) 1.14

Streptococcus pneumoniae and Pseudomonas aeruginosa pneumonia induce distinct host responses. Crit Care Med (2010) 1.14

Implementation of a mandatory checklist of protocols and objectives improves compliance with a wide range of evidence-based intensive care unit practices. Crit Care Med (2009) 1.11

Efficacy and safety of an insulin infusion protocol in a surgical ICU. J Am Coll Surg (2005) 1.10

The impact of a simple, low-cost oral care protocol on ventilator-associated pneumonia rates in a surgical intensive care unit. J Intensive Care Med (2009) 1.08

Improved extubation rates and earlier liberation from mechanical ventilation with implementation of a daily spontaneous-breathing trial protocol. J Am Coll Surg (2007) 1.08

Age disproportionately increases sepsis-induced apoptosis in the spleen and gut epithelium. Shock (2004) 1.07

Realistic simulations of proton transport along the gramicidin channel: demonstrating the importance of solvation effects. J Phys Chem B (2005) 1.04

Quasispecies theory for finite populations. Phys Rev E Stat Nonlin Soft Matter Phys (2010) 1.03

Molecular diagnostics in sepsis: from bedside to bench. J Am Coll Surg (2006) 1.02

The impact of bedside behavior on catheter-related bacteremia in the intensive care unit. Arch Surg (2004) 1.02

The frequency and effects of cytochrome P450 (CYP) 2C9 polymorphisms in patients receiving warfarin. J Am Coll Surg (2002) 1.00

Heterogeneous diversity of spacers within CRISPR (clustered regularly interspaced short palindromic repeats). Phys Rev Lett (2010) 1.00

Antibiotics improve survival and alter the inflammatory profile in a murine model of sepsis from Pseudomonas aeruginosa pneumonia. Shock (2003) 1.00

Prevalence and Impact of Unknown Diabetes in the ICU. Crit Care Med (2015) 0.99

A database of new zeolite-like materials. Phys Chem Chem Phys (2011) 0.98

The role of heat shock protein 70 in mediating age-dependent mortality in sepsis. J Immunol (2011) 0.98

Low-dimensional clustering detects incipient dominant influenza strain clusters. Protein Eng Des Sel (2010) 0.98

Evolution of H3N2 influenza virus in a guinea pig model. PLoS One (2011) 0.97

Microarray and EST database estimates of mRNA expression levels differ: the protein length versus expression curve for C. elegans. BMC Genomics (2004) 0.94

A novel sequence-based antigenic distance measure for H1N1, with application to vaccine effectiveness and the selection of vaccine strains. Protein Eng Des Sel (2010) 0.93

Quantifying selection and diversity in viruses by entropy methods, with application to the haemagglutinin of H3N2 influenza. J R Soc Interface (2011) 0.92

Sepsis gene expression profiling: murine splenic compared with hepatic responses determined by using complementary DNA microarrays. Crit Care Med (2002) 0.92

Sculpting the immunological response to dengue fever by polytopic vaccination. Vaccine (2005) 0.92

Bcl-2 inhibits gut epithelial apoptosis induced by acute lung injury in mice but has no effect on survival. Shock (2003) 0.92

Quasispecies theory for horizontal gene transfer and recombination. Phys Rev E Stat Nonlin Soft Matter Phys (2008) 0.89

Dynamical density delay maps: simple, new method for visualising the behaviour of complex systems. BMC Med Inform Decis Mak (2014) 0.89

Association between lymphotoxin-alpha (tumor necrosis factor-beta) intron polymorphism and predisposition to severe sepsis is modified by gender and age. Crit Care Med (2010) 0.88

Toward optimal display of physiologic status in critical care: I. Recreating bedside displays from archived physiologic data. J Crit Care (2010) 0.87

Surgeons and their patients near the end of life. Crit Care Med (2010) 0.86

Using systems biology to simplify complex disease: immune cartography. Crit Care Med (2009) 0.86

Amino acid alphabet size in protein evolution experiments: better to search a small library thoroughly or a large library sparsely? Protein Eng Des Sel (2008) 0.85

Synthesis of a specified, silica molecular sieve by using computationally predicted organic structure-directing agents. Angew Chem Int Ed Engl (2014) 0.85

Selective pressure to increase charge in immunodominant epitopes of the H3 hemagglutinin influenza protein. J Mol Evol (2010) 0.85

Is there a role for growth hormone therapy in refractory critical illness? Curr Opin Crit Care (2008) 0.84

The digital patient: predicting physiologic dynamics with mathematical models. Crit Care Med (2009) 0.84

A new safety event reporting system improves physician reporting in the surgical intensive care unit. J Am Coll Surg (2006) 0.84

Spontaneous emergence of modularity in a model of evolving individuals and in real networks. Phys Rev E Stat Nonlin Soft Matter Phys (2009) 0.83

Proceedings from the Montebello Round Table Discussion. Second annual conference on Complexity and Variability discusses research that brings innovation to the bedside. J Crit Care (2011) 0.83

National estimates of hospitalization charges for the acute care of traumatic brain injuries. Brain Inj (2003) 0.83

Using "off-the-shelf" tools for terabyte-scale waveform recording in intensive care: computer system design, database description and lessons learned. Comput Methods Programs Biomed (2010) 0.83

Hierarchical evolution of animal body plans. Dev Biol (2009) 0.83

Extra credit*. Crit Care Med (2012) 0.83

Intestine-specific overexpression of IL-10 improves survival in polymicrobial sepsis. Shock (2008) 0.83

Comment on Ndifon et al., "On the use of hemagglutination-inhibition for influenza surveillance: Surveillance data are predictive of influenza vaccine effectiveness". Vaccine (2009) 0.83

Physical model of the immune response of bacteria against bacteriophage through the adaptive CRISPR-Cas immune system. Phys Biol (2013) 0.82

Iron dysregulation combined with aging prevents sepsis-induced apoptosis. J Surg Res (2005) 0.82

Modulation of base-specific mutation and recombination rates enables functional adaptation within the context of the genetic code. J Mol Evol (2004) 0.82

Physical theory of the competition that allows HIV to escape from the immune system. Phys Rev Lett (2006) 0.82

Glassy dynamics in the adaptive immune response prevents autoimmune disease. Phys Rev Lett (2005) 0.82

Fractals in clinical hemodynamics. Anesthesiology (2012) 0.82

In silico prediction of MOFs with high deliverable capacity or internal surface area. Phys Chem Chem Phys (2015) 0.81

Pharmacoepidemiology of QT-interval prolonging drug administration in critically ill patients. Pharmacoepidemiol Drug Saf (2008) 0.81

Impact of a Sequential Intervention on Albumin Utilization in Critical Care. Crit Care Med (2016) 0.81

Computerized content analysis of conversational interactions. Comput Inform Nurs (2003) 0.80

Coagulation inhibitors in the treatment of sepsis. Expert Opin Investig Drugs (2002) 0.80

Mechanical and dielectric properties of pure-silica-zeolite low-k materials. Angew Chem Int Ed Engl (2006) 0.80

Sepsis through the eyes of an engineer -- why treatments have succeeded and failed. Crit Rev Biomed Eng (2012) 0.80

Evaluation of the applicability, efficacy, and safety of a thromboembolic event prophylaxis guideline designed for quality improvement of the traumatically injured patient. J Trauma (2005) 0.80