PubRank

Michael T Lewis

Author PubWeight™ 63.85‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy. J Natl Cancer Inst 2008 11.93
2 Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features. Proc Natl Acad Sci U S A 2009 7.95
3 Constitutive activation of smoothened (SMO) in mammary glands of transgenic mice leads to increased proliferation, altered differentiation and ductal dysplasia. Development 2007 3.07
4 A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models. Cancer Res 2013 2.63
5 Evidence that an early pregnancy causes a persistent decrease in the number of functional mammary epithelial stem cells--implications for pregnancy-induced protection against breast cancer. Stem Cells 2008 1.96
6 Constitutively active type I insulin-like growth factor receptor causes transformation and xenograft growth of immortalized mammary epithelial cells and is accompanied by an epithelial-to-mesenchymal transition mediated by NF-kappaB and snail. Mol Cell Biol 2007 1.89
7 Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation. J Cell Biol 2009 1.65
8 Introduction of oncogenes into mammary glands in vivo with an avian retroviral vector initiates and promotes carcinogenesis in mouse models. Proc Natl Acad Sci U S A 2006 1.60
9 Patterns of resistance and incomplete response to docetaxel by gene expression profiling in breast cancer patients. J Clin Oncol 2005 1.58
10 Mesenchymal stem cells promote mammosphere formation and decrease E-cadherin in normal and malignant breast cells. PLoS One 2010 1.49
11 Patient-derived xenograft models of breast cancer and their predictive power. Breast Cancer Res 2015 1.43
12 Androgen receptor overexpression induces tamoxifen resistance in human breast cancer cells. Breast Cancer Res Treat 2009 1.35
13 Cyclopamine inhibition of human breast cancer cell growth independent of Smoothened (Smo). Breast Cancer Res Treat 2008 1.27
14 High IGF-IR activity in triple-negative breast cancer cell lines and tumorgrafts correlates with sensitivity to anti-IGF-IR therapy. Clin Cancer Res 2010 1.20
15 Preclinical and clinical studies of gamma secretase inhibitors with docetaxel on human breast tumors. Clin Cancer Res 2013 1.20
16 Selective small molecule Stat3 inhibitor reduces breast cancer tumor-initiating cells and improves recurrence free survival in a human-xenograft model. PLoS One 2012 1.14
17 Paracrine Wnt signaling both promotes and inhibits human breast tumor growth. Proc Natl Acad Sci U S A 2013 1.11
18 Estrogen promotes ER-negative tumor growth and angiogenesis through mobilization of bone marrow-derived monocytes. Cancer Res 2012 1.09
19 Activation of Erk by sonic hedgehog independent of canonical hedgehog signalling. Int J Biochem Cell Biol 2010 1.07
20 Cancer stem cell markers are enriched in normal tissue adjacent to triple negative breast cancer and inversely correlated with DNA repair deficiency. Breast Cancer Res 2013 1.06
21 Decreased TGFbeta signaling and increased COX2 expression in high risk women with increased mammographic breast density. Breast Cancer Res Treat 2009 1.04
22 Ptch1 is required locally for mammary gland morphogenesis and systemically for ductal elongation. Development 2009 1.03
23 Methods for preparing fluorescent and neutral red-stained whole mounts of mouse mammary glands. J Mammary Gland Biol Neoplasia 2009 0.99
24 STAT3 signaling is activated preferentially in tumor-initiating cells in claudin-low models of human breast cancer. Stem Cells 2014 0.99
25 Constitutive activation of smoothened leads to female infertility and altered uterine differentiation in the mouse. Biol Reprod 2010 0.98
26 Cancer stem cell, niche and EGFR decide tumor development and treatment response: A bio-computational simulation study. J Theor Biol 2010 0.98
27 Cisplatin@US-tube carbon nanocapsules for enhanced chemotherapeutic delivery. Biomaterials 2011 0.98
28 Altered differentiation and paracrine stimulation of mammary epithelial cell proliferation by conditionally activated Smoothened. Dev Biol 2011 0.96
29 Characterizing cancer cells with cancer stem cell-like features in 293T human embryonic kidney cells. Mol Cancer 2010 0.95
30 Dicer-mediated upregulation of BCRP confers tamoxifen resistance in human breast cancer cells. Clin Cancer Res 2011 0.92
31 Hedgehog signaling in the normal and neoplastic mammary gland. Curr Drug Targets 2010 0.88
32 Integrative physical oncology. Wiley Interdiscip Rev Syst Biol Med 2011 0.88
33 ID4 regulates mammary gland development by suppressing p38MAPK activity. Development 2011 0.86
34 Separation by cell size enriches for mammary stem cell repopulation activity. Stem Cells Transl Med 2013 0.84
35 Faith, heresy and the cancer stem cell hypothesis. Future Oncol 2008 0.79
36 Methods in mammary gland biology and breast cancer research: an update. J Mammary Gland Biol Neoplasia 2009 0.78
37 The more things change... the more things change: developmental plasticity of tumor-initiating mammary epithelial cells. Breast Cancer Res 2010 0.76
38 Embryogenesis and oncogenesis: Dr Jekyll and Mr Hyde. J Mammary Gland Biol Neoplasia 2004 0.75
39 Scaffold Attachment Factor B1 (SAFB1) heterozygosity does not influence Wnt-1 or DMBA-induced tumorigenesis. Mol Cancer 2009 0.75
40 Erratum: Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation. Nat Cell Biol 2016 0.75
41 Tumor-initiating cells and treatment resistance: how goes the war? J Mammary Gland Biol Neoplasia 2009 0.75