| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Topotecan versus cyclophosphamide, doxorubicin, and vincristine for the treatment of recurrent small-cell lung cancer.
|
J Clin Oncol
|
1999
|
3.48
|
|
2
|
Validity of sexual histories in a prospective study of male sexual contacts of men with AIDS or an AIDS-related condition.
|
Am J Epidemiol
|
1988
|
2.81
|
|
3
|
Twenty-two years of phase III trials for patients with advanced non-small-cell lung cancer: sobering results.
|
J Clin Oncol
|
2001
|
2.73
|
|
4
|
Second primary cancers related to smoking and treatment of small-cell lung cancer. Lung Cancer Working Cadre.
|
J Natl Cancer Inst
|
1997
|
2.52
|
|
5
|
Treatment of nonresectable hepatocellular carcinoma with intrahepatic 90Y-microspheres.
|
J Nucl Med
|
2000
|
2.07
|
|
6
|
Risk factors for HIV infection in male sexual contacts of men with AIDS or an AIDS-related condition.
|
Am J Epidemiol
|
1988
|
2.05
|
|
7
|
Second primary malignancies following diagnosis of small-cell lung cancer.
|
J Clin Oncol
|
1992
|
1.77
|
|
8
|
Efficacy of everolimus (RAD001) in patients with advanced NSCLC previously treated with chemotherapy alone or with chemotherapy and EGFR inhibitors.
|
Ann Oncol
|
2009
|
1.68
|
|
9
|
Cancer incidence among Canadian kidney transplant recipients.
|
Am J Transplant
|
2007
|
1.66
|
|
10
|
Randomized study of CODE versus alternating CAV/EP for extensive-stage small-cell lung cancer: an Intergroup Study of the National Cancer Institute of Canada Clinical Trials Group and the Southwest Oncology Group.
|
J Clin Oncol
|
1999
|
1.63
|
|
11
|
The reliability of sexual histories in AIDS-related research: evaluation of an interview-administered questionnaire.
|
Can J Public Health
|
1987
|
1.60
|
|
12
|
Combined modality induction therapy without maintenance chemotherapy for small cell carcinoma of the lung.
|
J Clin Oncol
|
1984
|
1.51
|
|
13
|
Amplification of telomerase (hTERT) gene is a poor prognostic marker in non-small-cell lung cancer.
|
Br J Cancer
|
2006
|
1.44
|
|
14
|
Diffuse malignant mesothelioma of the pleura in Ontario and Quebec: a retrospective study of 332 patients.
|
J Clin Oncol
|
1989
|
1.42
|
|
15
|
Lymphoma of the gastrointestinal tract.
|
Semin Oncol
|
1999
|
1.41
|
|
16
|
Sexual behaviour changes in a cohort of male sexual contacts of men with HIV disease: a three-year overview.
|
Can J Public Health
|
1991
|
1.40
|
|
17
|
Superiority of alternating non-cross-resistant chemotherapy in extensive small cell lung cancer. A multicenter, randomized clinical trial by the National Cancer Institute of Canada.
|
Ann Intern Med
|
1987
|
1.38
|
|
18
|
Activity of gemcitabine in patients with non-small cell lung cancer: a multicentre, extended phase II study.
|
Eur J Cancer
|
1996
|
1.32
|
|
19
|
VP-16 and cisplatin as first-line therapy for small-cell lung cancer.
|
J Clin Oncol
|
1985
|
1.30
|
|
20
|
Extragonadal germ cell tumors. A 14-year Toronto experience.
|
Cancer
|
1994
|
1.27
|
|
21
|
Detection of occult low-grade b-cell non-Hodgkin's lymphoma in patients with chronic hepatitis C infection and mixed cryoglobulinemia.
|
Hepatology
|
1999
|
1.26
|
|
22
|
A prospective study of male sexual contacts of men with AIDS-related conditions (ARC) or AIDS: HTLV-III antibody, clinical, and immune function status at induction.
|
Can J Public Health
|
1986
|
1.26
|
|
23
|
Lung cancer practice guidelines: lessons learned and issues addressed by the Ontario Lung Cancer Disease Site Group.
|
J Clin Oncol
|
1997
|
1.21
|
|
24
|
Ketoconazole in the management of paraneoplastic Cushing's syndrome secondary to ectopic adrenocorticotropin production.
|
J Clin Oncol
|
1995
|
1.20
|
|
25
|
A randomized study of oral nutritional support versus ad lib nutritional intake during chemotherapy for advanced colorectal and non-small-cell lung cancer.
|
J Clin Oncol
|
1987
|
1.19
|
|
26
|
Neurologic disorders in patients with small cell lung cancer.
|
Cancer
|
1987
|
1.15
|
|
27
|
Hepatocellular carcinoma: pilot trial of treatment with Y-90 microspheres.
|
Radiology
|
1989
|
1.15
|
|
28
|
Phase II study of amonafide: results of treatment and lessons learned from the study of an investigational agent in previously untreated patients with extensive small-cell lung cancer.
|
J Clin Oncol
|
1990
|
1.13
|
|
29
|
Two novel BRM insertion promoter sequence variants are associated with loss of BRM expression and lung cancer risk.
|
Oncogene
|
2011
|
1.12
|
|
30
|
Induction treatment before surgery for non-small cell lung cancer.
|
Lung Cancer
|
2003
|
1.12
|
|
31
|
Differential expression of matrix metalloproteinases and their inhibitors in non-small cell lung cancer.
|
J Pathol
|
2000
|
1.09
|
|
32
|
Expression and prognostic significance of metalloproteinases and their tissue inhibitors in patients with small-cell lung cancer.
|
J Clin Oncol
|
1999
|
1.08
|
|
33
|
Etoposide (VP-16) and cisplatin: an effective treatment for relapse in small-cell lung cancer.
|
J Clin Oncol
|
1985
|
1.08
|
|
34
|
Cofactors of progression to acquired immunodeficiency syndrome in a cohort of male sexual contacts of men with human immunodeficiency virus disease.
|
Am J Epidemiol
|
1990
|
1.07
|
|
35
|
The prognostic significance of pretreatment serum lactate dehydrogenase in patients with small-cell lung cancer.
|
J Clin Oncol
|
1991
|
1.06
|
|
36
|
Elevated levels of interferon-induced 2'-5' oligoadenylate synthetase in generalized persistent lymphadenopathy and the acquired immunodeficiency syndrome.
|
J Infect Dis
|
1985
|
1.06
|
|
37
|
Influence of age on the treatment of limited-stage small-cell lung cancer.
|
J Clin Oncol
|
1996
|
1.05
|
|
38
|
Limited impact of total parenteral nutrition on nutritional status during treatment for small cell lung cancer.
|
Cancer Res
|
1985
|
1.04
|
|
39
|
Adenovirus-mediated wild-type p53 gene transfer in patients receiving chemotherapy for advanced non-small-cell lung cancer: results of a multicenter phase II study.
|
J Clin Oncol
|
2001
|
1.04
|
|
40
|
Tetracycline sclerosis in the management of malignant pericardial effusion.
|
J Clin Oncol
|
1985
|
1.04
|
|
41
|
Economic issues in lung cancer: a review.
|
J Clin Oncol
|
1998
|
1.04
|
|
42
|
Small-cell carcinoma of the lung: derivation of a prognostic staging system.
|
J Clin Oncol
|
1991
|
1.03
|
|
43
|
Factors associated with referral to medical oncology and subsequent use of adjuvant chemotherapy for non-small-cell lung cancer: a population-based study.
|
Curr Oncol
|
2013
|
1.02
|
|
44
|
Reduced expression of the cell cycle inhibitor p27Kip1 in non-small cell lung carcinoma: a prognostic factor independent of Ras.
|
Cancer Res
|
1999
|
1.02
|
|
45
|
Cross-validation study of class III beta-tubulin as a predictive marker for benefit from adjuvant chemotherapy in resected non-small-cell lung cancer: analysis of four randomized trials.
|
Ann Oncol
|
2011
|
1.01
|
|
46
|
The influence of sex and histology on outcomes in non-small-cell lung cancer: a pooled analysis of five randomized trials.
|
Ann Oncol
|
2010
|
1.01
|
|
47
|
Superior vena caval obstruction syndrome in small cell lung cancer.
|
Cancer
|
1986
|
1.00
|
|
48
|
Reduction in local recurrence and improved survival in surgically treated patients with small cell lung cancer.
|
J Thorac Cardiovasc Surg
|
1983
|
1.00
|
|
49
|
The strength of female sex as a prognostic factor in small-cell lung cancer: a pooled analysis of chemotherapy trials from the Manchester Lung Group and Medical Research Council Clinical Trials Unit.
|
Ann Oncol
|
2009
|
1.00
|
|
50
|
Is bone marrow examination in small-cell lung cancer really necessary?
|
Ann Intern Med
|
1986
|
0.97
|
|
51
|
Treatment-emergent hypertension and outcomes in patients with advanced non-small-cell lung cancer receiving chemotherapy with or without the vascular endothelial growth factor receptor inhibitor cediranib: NCIC Clinical Trials Group Study BR24.
|
Ann Oncol
|
2010
|
0.96
|
|
52
|
Combined cisplatin and gemcitabine for non-small cell lung cancer: influence of scheduling on toxicity and drug delivery.
|
Semin Oncol
|
1998
|
0.95
|
|
53
|
Carcinoembryonic antigen: a useful prognostic marker in small-cell lung cancer.
|
J Clin Oncol
|
1985
|
0.94
|
|
54
|
An evaluation of the possible interaction of gastric acid suppressing medication and the EGFR tyrosine kinase inhibitor erlotinib.
|
Lung Cancer
|
2013
|
0.94
|
|
55
|
The influence of age on the delivery, tolerance, and efficacy of thoracic irradiation in the combined modality treatment of limited stage small cell lung cancer.
|
Int J Radiat Oncol Biol Phys
|
1999
|
0.93
|
|
56
|
Cyclophosphamide and fluorouracil combined with mitoxantrone versus doxorubicin for breast cancer: superiority of doxorubicin.
|
J Clin Oncol
|
1997
|
0.93
|
|
57
|
Phase I-II study of high-dose epirubicin in advanced non-small-cell lung cancer.
|
J Clin Oncol
|
1992
|
0.91
|
|
58
|
Ketoconazole. Use in the treatment of ectopic adrenocorticotropic hormone production and Cushing's syndrome in small-cell lung cancer.
|
Arch Intern Med
|
1985
|
0.90
|
|
59
|
Intraocular lymphoma: report of three cases and review of the literature.
|
Am J Clin Oncol
|
1988
|
0.89
|
|
60
|
Prospective comparison of the sclerosing agents doxycycline and bleomycin for the primary management of malignant pericardial effusion and cardiac tamponade.
|
J Clin Oncol
|
1996
|
0.89
|
|
61
|
Effects of total parenteral nutrition and chemotherapy on the metabolic derangements in small cell lung cancer.
|
Cancer Res
|
1984
|
0.88
|
|
62
|
Enhancing treatment decision-making: pilot study of a treatment decision aid in stage IV non-small cell lung cancer.
|
Br J Cancer
|
2008
|
0.88
|
|
63
|
Pharmacogenetic analysis of BR.21, a placebo-controlled randomized phase III clinical trial of erlotinib in advanced non-small cell lung cancer.
|
J Thorac Oncol
|
2012
|
0.87
|
|
64
|
Induction chemotherapy with mitomycin, vindesine, and cisplatin for stage III unresectable non-small-cell lung cancer: results of the Toronto Phase II Trial.
|
J Clin Oncol
|
1992
|
0.87
|
|
65
|
VP-16 alone and in combination with cisplatin in previously treated patients with small cell lung cancer.
|
Cancer
|
1984
|
0.87
|
|
66
|
The role of the epidermal growth factor receptor tyrosine kinase inhibitors as therapy for advanced, metastatic, and recurrent non-small-cell lung cancer: a Canadian national consensus statement.
|
Curr Oncol
|
2009
|
0.86
|
|
67
|
Validation of treatment induced specific adverse effect as a predictor of treatment benefit: a case study of NCIC CTG BR21.
|
Contemp Clin Trials
|
2008
|
0.86
|
|
68
|
A guide to the investigation and treatment of patients with AIDS and AIDS-related disorders.
|
CMAJ
|
1986
|
0.86
|
|
69
|
A phase I dose-escalation study of aflibercept administered in combination with pemetrexed and cisplatin in patients with advanced solid tumours.
|
Br J Cancer
|
2012
|
0.86
|
|
70
|
Late neurological complications after prophylactic cranial irradiation in patients with small-cell lung cancer: the Toronto experience.
|
J Clin Oncol
|
1990
|
0.86
|
|
71
|
Pericardial sclerosis as the primary management of malignant pericardial effusion and cardiac tamponade.
|
J Thorac Cardiovasc Surg
|
1996
|
0.85
|
|
72
|
Polymorphisms of inflammatory and metalloproteinase genes, Helicobacter pylori infection and the risk of oesophageal adenocarcinoma.
|
Br J Cancer
|
2008
|
0.85
|
|
73
|
Intramedullary spinal cord metastases from small cell carcinoma of the lung.
|
J Clin Oncol
|
1983
|
0.84
|
|
74
|
Lymphoproliferative disorders after liver transplantation: imaging features.
|
Abdom Imaging
|
2001
|
0.83
|
|
75
|
Co-expression of epidermal growth factor receptor and transforming growth factor-alpha is independent of ras mutations in lung adenocarcinoma.
|
Lung Cancer
|
2000
|
0.82
|
|
76
|
VP-16 and carboplatin in previously untreated patients with extensive small cell lung cancer: a study of the National Cancer Institute of Canada Clinical Trials Group.
|
Br J Cancer
|
1988
|
0.82
|
|
77
|
Impact of hemoglobin levels on outcomes of adjuvant chemotherapy in resected non-small cell lung cancer: the JBR.10 trial experience.
|
Lung Cancer
|
2006
|
0.81
|
|
78
|
Acute lymphoblastic leukemia. Possible origin from a mediastinal germ cell tumor.
|
Cancer
|
1984
|
0.81
|
|
79
|
Phase II evaluation of Lonidamine in patients with advanced malignancy.
|
Oncology
|
1984
|
0.81
|
|
80
|
The impact of anemia on outcome of chemoradiation for limited small-cell lung cancer: a combined analysis of studies of the National Cancer Institute of Canada Clinical Trials Group.
|
Ann Oncol
|
2007
|
0.80
|
|
81
|
Changes in body composition in patients with small-cell lung cancer. The effect of total parenteral nutrition as an adjunct to chemotherapy.
|
Ann Intern Med
|
1984
|
0.80
|
|
82
|
Human herpesvirus 8 and renal transplantation.
|
N Engl J Med
|
1999
|
0.79
|
|
83
|
An economic analysis of the INTEREST trial, a randomized trial of docetaxel versus gefitinib as second-/third-line therapy in advanced non-small-cell lung cancer.
|
Ann Oncol
|
2011
|
0.79
|
|
84
|
Acute leukemia during pregnancy: the Toronto Leukemia Study Group experience with long-term follow-up of children exposed in utero to chemotherapeutic agents.
|
J Clin Oncol
|
1987
|
0.79
|
|
85
|
Therapy-related leukemia and myelodysplasia in small-cell lung cancer. Report of a case and results of morphologic, cytogenetic, and bone marrow culture studies in long-term survivors.
|
Arch Intern Med
|
1986
|
0.78
|
|
86
|
Using serial observations to identify predictors of progression to AIDS in the Toronto Sexual Contact Study.
|
J Clin Epidemiol
|
1992
|
0.78
|
|
87
|
Combination chemotherapy with bleomycin, etoposide, and cisplatin in metastatic non-small-cell lung cancer.
|
J Clin Oncol
|
1985
|
0.78
|
|
88
|
Gemcitabine in the treatment of non-small-cell lung cancer.
|
Ann Oncol
|
1995
|
0.78
|
|
89
|
Prospective assessment of cardiac function in patients with Kaposi's sarcoma and the acquired immune deficiency syndrome.
|
Clin Invest Med
|
1991
|
0.78
|
|
90
|
VP-16, ifosfamide and cisplatin (VIP) for extensive small cell lung cancer.
|
Eur J Cancer
|
1994
|
0.78
|
|
91
|
First-line therapy with VP-16 and cisplatin for small-cell lung cancer.
|
Semin Oncol
|
1986
|
0.78
|
|
92
|
Hepatic arterial infusion of mitoxantrone in the treatment of primary hepatocellular carcinoma.
|
J Clin Oncol
|
1987
|
0.78
|
|
93
|
Dexamethasone/ifosfamide/cisplatin/etoposide (DICE) as therapy for patients with advanced refractory non-Hodgkin's lymphoma: preliminary report of a phase II study.
|
Ann Oncol
|
1991
|
0.77
|
|
94
|
HIV-associated lymphoma of the gastrointestinal tract: the University of Toronto AIDS-Lymphoma Study Group experience.
|
Leuk Lymphoma
|
1995
|
0.76
|
|
95
|
Phase II trial of docetaxel with dexamethasone premedication in patients with advanced non-small cell lung cancer: the Canadian experience.
|
Invest New Drugs
|
1999
|
0.76
|
|
96
|
The probability of progression to AIDS in a cohort of male sexual contacts of men with HIV disease.
|
Int J Epidemiol
|
1992
|
0.76
|
|
97
|
Myasthenic syndrome and small cell cancer of the lung. Variable response to antineoplastic therapy.
|
Arch Intern Med
|
1984
|
0.76
|
|
98
|
Clinical use of blood, blood components and blood products.
|
Can Med Assoc J
|
1979
|
0.75
|
|
99
|
The relationship between 2-5A synthetase levels and persistent lymphadenopathy in homosexual men with antibodies to HTLV-III.
|
Clin Invest Med
|
1986
|
0.75
|
|
100
|
AIDS in a patient with hemophilia receiving mainly cryoprecipitate.
|
Can Med Assoc J
|
1984
|
0.75
|
|
101
|
Anti-IgA-mediated transfusion reactions in Canada.
|
Can Med Assoc J
|
1984
|
0.75
|
|
102
|
Phase II evaluation of bisantrene in patients with advanced renal cell carcinoma.
|
Cancer Treat Rep
|
1985
|
0.75
|
|
103
|
Phase II study of pegylated liposomal doxorubicin HCl (Caelyx) in combination with cyclophosphamide and vincristine as second-line treatment of patients with small cell lung cancer.
|
Lung Cancer
|
2006
|
0.75
|
|
104
|
5-Fluorouracil with folinic acid is not effective against metastatic adenocarcinoma of the lung.
|
Cancer Invest
|
1990
|
0.75
|
|
105
|
Phase II evaluation of bisantrene in patients with advanced non-small cell lung carcinoma.
|
Cancer Treat Rep
|
1985
|
0.75
|
|
106
|
Phase I trial of granulocyte-macrophage colony-stimulating factor with high-dose cisplatin and etoposide for treatment of small-cell lung cancer: a study of the National Cancer Institute of Canada Clinical Trials Group.
|
J Natl Cancer Inst
|
1992
|
0.75
|
|
107
|
Treatment of AIDS-related non-Hodgkin's lymphoma with a twelve week chemotherapy program.
|
Leuk Lymphoma
|
1992
|
0.75
|
|
108
|
5-Fluorouracil, adriamycin, and mitomycin-C (FAM) in the treatment of inoperable adenocarcinoma of the lung.
|
Am J Clin Oncol
|
1986
|
0.75
|
|
109
|
Comparison of three HIV antigen detection kits in sequential sera from a cohort of homosexual men.
|
J Acquir Immune Defic Syndr
|
1991
|
0.75
|
|
110
|
Safety of therapeutic anticoagulation in patients with multiple myeloma receiving autologous stem cell transplantation.
|
Bone Marrow Transplant
|
1998
|
0.75
|
|
111
|
Lymphoproliferative disorders after lung transplantation: imaging features.
|
Radiology
|
1998
|
0.75
|
|
112
|
Carcinoembryonic antigen, arginine vasopressin and calcitonin as markers of early small-cell lung cancer relapse.
|
Tumour Biol
|
1989
|
0.75
|
|
113
|
Methyl-CCNU and methotrexate therapy in patients with advanced colorectal cancer after failure of 5-fluorouracil chemotherapy.
|
Am J Clin Oncol
|
1986
|
0.75
|
|
114
|
Phase II study of sulofenur (LY186641) in untreated patients with extensive small cell lung cancer.
|
Ann Oncol
|
1992
|
0.75
|
|
115
|
Induction treatment for resectable non-small-cell lung cancer.
|
Lung Cancer
|
1997
|
0.75
|
|
116
|
A phase II study of ifosfamide in combination with etoposide and cisplatin in the treatment of extensive small cell lung cancer.
|
Semin Oncol
|
1992
|
0.75
|