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1
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Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome.
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Cell
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1996
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7.86
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2
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Medulloblastomas of the desmoplastic variant carry mutations of the human homologue of Drosophila patched.
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Cancer Res
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1997
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2.45
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3
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Nevoid basal cell carcinoma syndrome: review of 118 affected individuals.
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Am J Med Genet
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1994
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2.06
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4
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Isolation of a human gene with protein sequence similarity to human and murine int-1 and the Drosophila segment polarity mutant wingless.
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EMBO J
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1988
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1.67
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5
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Cloning the mouse homolog of the human cystic fibrosis transmembrane conductance regulator gene.
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Genomics
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1991
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1.48
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6
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A mammalian patched homolog is expressed in target tissues of sonic hedgehog and maps to a region associated with developmental abnormalities.
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J Biol Chem
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1996
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1.44
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7
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ATF3 and p15PAF are novel gatekeepers of genomic integrity upon UV stress.
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Cell Death Differ
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2009
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1.27
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8
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Isolation and characterization of human patched 2 (PTCH2), a putative tumour suppressor gene inbasal cell carcinoma and medulloblastoma on chromosome 1p32.
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Hum Mol Genet
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1999
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1.15
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9
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Further localization of the gene for nevoid basal cell carcinoma syndrome (NBCCS) in 15 Australasian families: linkage and loss of heterozygosity.
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Am J Hum Genet
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1993
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1.02
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10
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DHPLC analysis of patients with Nevoid Basal Cell Carcinoma Syndrome reveals novel PTCH missense mutations in the sterol-sensing domain.
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Hum Mutat
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2005
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1.01
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11
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Characterisation of human patched germ line mutations in naevoid basal cell carcinoma syndrome.
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Hum Genet
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1997
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0.93
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12
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Fine deletion mapping on the long arm of chromosome 9 in sporadic and familial basal cell carcinomas.
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Hum Mol Genet
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1995
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0.89
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13
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Sequence variants of DLC1 in colorectal and ovarian tumours.
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Hum Mutat
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2000
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0.87
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14
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A new polymorphic locus, D7S411, isolated by cloning from preparative pulse-field gels is close to the mutation causing cystic fibrosis.
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Genomics
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1990
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0.85
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15
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The spectrum of patched mutations in a collection of Australian basal cell carcinomas.
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Hum Mutat
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2000
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0.83
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16
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The effects of splice site mutations in patients with naevoid basal cell carcinoma syndrome.
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Hum Genet
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1998
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0.79
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17
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Mapping the multiple self-healing squamous epithelioma (MSSE) gene and investigation of xeroderma pigmentosum group A (XPA) and PATCHED (PTCH) as candidate genes.
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Hum Genet
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1997
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0.77
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18
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+P5 (D1S3309E), a novel target binding site for the Wilms' tumour suppressor 1 (WT1) gene, maps to human chromosome 1q21-->22.
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Cytogenet Cell Genet
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1996
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0.76
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19
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The apoptotic regulatory gene, BCL10, is mutated in sporadic mismatch repair deficient colorectal cancers.
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Cell Death Differ
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2000
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0.76
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20
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Novel mutation in the Delta7-dehydrocholesterol reductase gene in an Australian patient with Smith-Lemli-Opitz syndrome.
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Am J Med Genet
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2001
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0.75
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21
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Simple repeat polymorphism at the D9S151 locus.
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Hum Mol Genet
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1994
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0.75
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22
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Pulsed-field gel electrophoresis and FISH mapping of chromosome 9q22: placement of a novel zinc finger gene within the NBCCS and ESS1 region.
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Cytogenet Cell Genet
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1997
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0.75
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