Published in PLoS One on August 18, 2009
Notch signalling in T-cell lymphoblastic leukaemia/lymphoma and other haematological malignancies. J Pathol (2010) 2.58
NOTCH1 activation clinically antagonizes the unfavorable effect of PTEN inactivation in BFM-treated children with precursor T-cell acute lymphoblastic leukemia. Haematologica (2013) 1.06
Notch/HES1-mediated PARP1 activation: a cell type-specific mechanism for tumor suppression. Blood (2011) 1.00
Loss of aryl hydrocarbon receptor promotes gene changes associated with premature hematopoietic stem cell exhaustion and development of a myeloproliferative disorder in aging mice. Stem Cells Dev (2013) 0.90
SCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cells. PLoS Genet (2014) 0.84
Transient responses to NOTCH and TLX1/HOX11 inhibition in T-cell acute lymphoblastic leukemia/lymphoma. PLoS One (2011) 0.83
Notch1 signaling is involved in regulating Foxp3 expression in T-ALL. Cancer Cell Int (2013) 0.80
Enhanced Notch activation is advantageous but not essential for T cell lymphomagenesis in Id1 transgenic mice. PLoS One (2012) 0.77
FHL1C induces apoptosis in Notch1-dependent T-ALL cells through an interaction with RBP-J. BMC Cancer (2014) 0.75
High selective pressure for Notch1 mutations that induce Myc in T-cell acute lymphoblastic leukemia. Blood (2016) 0.75
Activation of Notch3 promotes pulmonary arterial smooth muscle cells proliferation via Hes1/p27Kip1 signaling pathway. FEBS Open Bio (2015) 0.75
Bruceantin inhibits multiple myeloma cancer stem cell proliferation. Cancer Biol Ther (2016) 0.75
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science (2004) 18.84
Signalling downstream of activated mammalian Notch. Nature (1995) 11.08
Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain. Nature (1998) 10.58
TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell (1991) 10.06
Deficient T cell fate specification in mice with an induced inactivation of Notch1. Immunity (1999) 8.33
Notch signaling. Science (1995) 7.22
NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth. Proc Natl Acad Sci U S A (2006) 6.80
Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia. Cancer Cell (2002) 6.64
c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma. Genes Dev (2006) 6.19
Notch1 expression in early lymphopoiesis influences B versus T lineage determination. Immunity (1999) 5.34
Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins. Cell (1994) 4.95
Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles. J Exp Med (1996) 4.79
Launching the T-cell-lineage developmental programme. Nat Rev Immunol (2008) 3.86
Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split. Genes Dev (1992) 3.85
Regulation of lymphoid development, differentiation, and function by the Notch pathway. Annu Rev Immunol (2005) 3.58
Involvement of c-myc in MuLV-induced T cell lymphomas in mice: frequency and mechanisms of activation. EMBO J (1984) 3.28
Notch signaling controls the generation and differentiation of early T lineage progenitors. Nat Immunol (2005) 3.26
The tal gene undergoes chromosome translocation in T cell leukemia and potentially encodes a helix-loop-helix protein. EMBO J (1990) 3.21
Positive selection of lymphocytes. Cell (1994) 2.86
Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras-initiated leukemia. J Clin Invest (2008) 2.73
Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice. EMBO J (2000) 2.41
High incidence of T-cell tumors in E2A-null mice and E2A/Id1 double-knockout mice. Mol Cell Biol (1997) 2.19
Notch activation is an early and critical event during T-Cell leukemogenesis in Ikaros-deficient mice. Mol Cell Biol (2006) 2.09
Early thymocyte development is regulated by modulation of E2A protein activity. J Exp Med (2001) 2.05
Regulation of lymphocyte development by Notch signaling. Nat Immunol (2007) 1.96
The bHLH gene Hes1 is essential for expansion of early T cell precursors. Genes Dev (1999) 1.95
An intermediate cell in thymocyte differentiation that expresses CD8 but not CD4 antigen. J Exp Med (1987) 1.93
Molecular characterization of a rat negative regulator with a basic helix-loop-helix structure predominantly expressed in the developing nervous system. J Biol Chem (1992) 1.93
TAL1/SCL induces leukemia by inhibiting the transcriptional activity of E47/HEB. Cancer Cell (2004) 1.88
TAL1, TAL2 and LYL1: a family of basic helix-loop-helix proteins implicated in T cell acute leukaemia. Semin Cancer Biol (1993) 1.82
Regulation of thymocyte differentiation: pre-TCR signals and beta-selection. Semin Immunol (2002) 1.75
Notch-induced E2A ubiquitination and degradation are controlled by MAP kinase activities. EMBO J (2003) 1.73
Disruption of thymocyte development and lymphomagenesis induced by SV40 T-antigen. Int Immunol (1990) 1.72
Massive apoptosis of thymocytes in T-cell-deficient Id1 transgenic mice. Mol Cell Biol (1999) 1.55
The Nrarp gene encodes an ankyrin-repeat protein that is transcriptionally regulated by the notch signaling pathway. Dev Biol (2001) 1.54
An analysis of T cell intrinsic roles of E2A by conditional gene disruption in the thymus. J Immunol (2002) 1.52
The earliest subpopulation of mouse thymocytes contains potent T, significant macrophage, and natural killer cell but no B-lymphocyte potential. Blood (2004) 1.40
Overexpression of the Helix-Loop-Helix protein Id2 blocks T cell development at multiple stages. Mol Immunol (1999) 1.33
Branching out to gain control: how the pre-TCR is linked to multiple functions. Immunol Today (2000) 1.28
Overexpression of the Notch target genes Hes in vivo induces lymphoid and myeloid alterations. Oncogene (2002) 1.26
Role for Hes1-induced phosphorylation in Groucho-mediated transcriptional repression. Mol Cell Biol (2002) 1.24
Expression and purification of a soluble tissue factor fusion protein with an epitope for an unusual calcium-dependent antibody. Protein Expr Purif (1992) 1.24
Notch1 promotes survival of E2A-deficient T cell lymphomas through pre-T cell receptor-dependent and -independent mechanisms. Blood (2006) 1.22
Pre-TCR-triggered ERK signalling-dependent downregulation of E2A activity in Notch3-induced T-cell lymphoma. EMBO Rep (2003) 1.18
A reassessment of the effect of activated Notch1 on CD4 and CD8 T cell development. J Immunol (2002) 1.18
Differentiation potential of 14-day fetal mouse thymocytes in organ culture. Analysis of CD4/CD8-defined single-positive and double-negative cells. J Immunol (1988) 1.16
Notch signaling in leukemia. Curr Opin Hematol (2001) 1.11
Breakpoints in the human T-cell antigen receptor alpha-chain locus in two T-cell leukaemia patients with chromosomal translocations. Nature (1985) 1.11
Helix-loop-helix proteins regulate pre-TCR and TCR signaling through modulation of Rel/NF-kappaB activities. Immunity (2002) 1.10
Identification of Notch target genes in uncommitted T-cell progenitors: No direct induction of a T-cell specific gene program. Leukemia (2006) 0.99
Notch signaling is involved in the regulation of Id3 gene transcription during Xenopus embryogenesis. Differentiation (2002) 0.99
Regulation of lymphocyte development by cell-type-specific interpretation of Notch signals. Mol Cell Biol (2008) 0.94
Hyperresponse to T-cell receptor signaling and apoptosis of Id1 transgenic thymocytes. Mol Cell Biol (2004) 0.92
The DNA binding activity of TAL-1 is not required to induce leukemia/lymphoma in mice. Oncogene (2001) 0.91
Rapid identification of UCA1 as a very sensitive and specific unique marker for human bladder carcinoma. Clin Cancer Res (2006) 1.97
The transcriptional program controlled by the stem cell leukemia gene Scl/Tal1 during early embryonic hematopoietic development. Blood (2009) 1.97
Notch-induced E2A ubiquitination and degradation are controlled by MAP kinase activities. EMBO J (2003) 1.73
Japanese encephalitis outbreak, Yuncheng, China, 2006. Emerg Infect Dis (2007) 1.56
STAT5-induced Id-1 transcription involves recruitment of HDAC1 and deacetylation of C/EBPbeta. EMBO J (2003) 1.53
Emergence of genotype I of Japanese encephalitis virus as the dominant genotype in Asia. J Virol (2011) 1.46
Id1, but not Id3, directs long-term repopulating hematopoietic stem-cell maintenance. Blood (2007) 1.39
Temperature can influence gastric accommodation and sensitivity in functional dyspepsia with epigastric pain syndrome. Dig Dis Sci (2012) 1.38
Primitive lymphoid progenitors in bone marrow with T lineage reconstituting potential. J Immunol (2006) 1.33
Interferon-producing killer dendritic cells (IKDCs) arise via a unique differentiation pathway from primitive c-kitHiCD62L+ lymphoid progenitors. Blood (2007) 1.32
Isolation and characterization of the full coding sequence of a novel densovirus from the mosquito Culex pipiens pallens. J Gen Virol (2008) 1.20
Interleukin-6 aborts lymphopoiesis and elevates production of myeloid cells in systemic lupus erythematosus-prone B6.Sle1.Yaa animals. Blood (2009) 1.17
Balance between Id and E proteins regulates myeloid-versus-lymphoid lineage decisions. Blood (2008) 1.16
Notch-induced E2A degradation requires CHIP and Hsc70 as novel facilitators of ubiquitination. Mol Cell Biol (2004) 1.10
Helix-loop-helix proteins regulate pre-TCR and TCR signaling through modulation of Rel/NF-kappaB activities. Immunity (2002) 1.10
The specific immune response to tumor antigen CP1 and its correlation with improved survival in colon cancer patients. Gastroenterology (2008) 0.99
Banna virus, China, 1987-2007. Emerg Infect Dis (2010) 0.99
Notch-induced Asb2 expression promotes protein ubiquitination by forming non-canonical E3 ligase complexes. Cell Res (2010) 0.96
Regulation of lymphocyte development by cell-type-specific interpretation of Notch signals. Mol Cell Biol (2008) 0.94
Hyperresponse to T-cell receptor signaling and apoptosis of Id1 transgenic thymocytes. Mol Cell Biol (2004) 0.92
Genetic diversity analyses of antimicrobial resistance genes in clinical Chryseobacterium meningosepticum isolated from Hefei, China. Int J Antimicrob Agents (2012) 0.92
Id1 attenuates Notch signaling and impairs T-cell commitment by elevating Deltex1 expression. Mol Cell Biol (2009) 0.92
Id1 potentiates NF-kappaB activation upon T cell receptor signaling. J Biol Chem (2006) 0.92
Ubiquitination and degradation of Tal1/SCL are induced by notch signaling and depend on Skp2 and CHIP. J Biol Chem (2007) 0.92
[0507JS60 virus isolated in Xinjiang was identified as Liaoning virus]. Bing Du Xue Bao (2008) 0.91
Serum fatty acid profiles using GC-MS and multivariate statistical analysis: potential biomarkers of Alzheimer's disease. Neurobiol Aging (2010) 0.90
The transcription factor Bright plays a role in marginal zone B lymphocyte development and autoantibody production. Mol Immunol (2011) 0.88
Sciatic nerve repair by acellular nerve xenografts implanted with BMSCs in rats xenograft combined with BMSCs. Synapse (2011) 0.87
A mechanism underlying NOTCH-induced and ubiquitin-mediated JAK3 degradation. J Biol Chem (2011) 0.87
Chronic TLR signaling impairs the long-term repopulating potential of hematopoietic stem cells of wild type but not Id1 deficient mice. PLoS One (2013) 0.87
Increased level of E protein activity during invariant NKT development promotes differentiation of invariant NKT2 and invariant NKT17 subsets. J Immunol (2013) 0.85
Improving the simultaneous removal efficiency of COD and color in a combined HABMR-CFASR system based MPDW. Part 1: optimization of operational parameters for HABMR by using response surface methodology. Bioresour Technol (2011) 0.84
Lymphoid lineage cells in adult murine bone marrow diverge from those of other blood cells at an early, hormone-sensitive stage. Semin Immunol (2002) 0.84
[Isolation and identification of arboviruses from mosquito pools in some regions of Liaoning province, China]. Zhonghua Liu Xing Bing Xue Za Zhi (2009) 0.83
A case of occult insulinoma localized by pancreatic dynamic enhanced spiral CT. World J Gastroenterol (2010) 0.82
Janus kinase 3: the controller and the controlled. Acta Biochim Biophys Sin (Shanghai) (2011) 0.81
Monocytes and Alzheimer's disease. Neurosci Bull (2011) 0.81
Experimental study of low dose ultrashortwave promoting nerve regeneration after acellular nerve allografts repairing the sciatic nerve gap of rats. Cell Mol Neurobiol (2007) 0.80
Investigation on the chemical constituents and variation of the flower buds of Lonicera species by UPLC-ESI-MS/MS and principle component analysis. Yao Xue Xue Bao (2009) 0.80
Determination of atractylenolide II in rat plasma by reversed-phase high-performance liquid chromatography. Biomed Chromatogr (2007) 0.79
Id1 induces apoptosis through inhibition of RORgammat expression. BMC Immunol (2008) 0.78
[The expressions of STAT3, WWOX and c-myc in human non small cell lung cancer tissue and correlativity analysis]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi (2010) 0.78
Quantitative assessment of the influence of cytochrome P450 2C19 gene polymorphisms and digestive tract cancer risk. Tumour Biol (2013) 0.77
Gatekeeper mechanisms for immature B cells. Nat Immunol (2002) 0.77
Enhanced Notch activation is advantageous but not essential for T cell lymphomagenesis in Id1 transgenic mice. PLoS One (2012) 0.77
Notch-regulated periphery B cell differentiation involves suppression of E protein function. J Immunol (2013) 0.76
Effects of 660-nm gallium-aluminum-arsenide low-energy laser on nerve regeneration after acellular nerve allograft in rats. Synapse (2010) 0.76
[Discussion of time and space differentiation of three-yin and three-yang in Shanghan Lun]. Zhong Xi Yi Jie He Xue Bao (2005) 0.76
Id1 has a physiological role in regulating early B lymphopoiesis. Cell Mol Immunol (2010) 0.76
Id1 expression promotes peripheral CD4+ T cell proliferation and survival upon TCR activation without co-stimulation. Biochem Biophys Res Commun (2013) 0.76
E proteins regulate osteoclast maturation and survival. J Bone Miner Res (2012) 0.75
Retracted Improving the efficiencies of simultaneous organic substance and nitrogen removal in a multi-stage loop membrane bioreactor-based PWWTP using an on-line Knowledge-Based Expert System. Water Res (2011) 0.75
Spectroscopic and molecular modeling studies on the interaction between a fluorine-containing triazole derivative and human serum albumin. Biol Trace Elem Res (2010) 0.75
Novel blood-based microRNA biomarkers for diagnosis of pancreatic cancer: a meta-analysis. Tumori (2015) 0.75
[Chemical constituents from the fruits of Areca catechu]. Zhong Yao Cai (2012) 0.75
[Effect of combined drug treatment on megacolon with severe constipation]. Zhonghua Yi Xue Za Zhi (2007) 0.75
Effects of glutamate and MK-801 on the metabolism of dopamine in the striatum of normal and parkinsonian rats. Sheng Li Xue Bao (2005) 0.75
Biocompatibility of acellular nerves of different mammalian species for nerve tissue engineering. Artif Cells Blood Substit Immobil Biotechnol (2011) 0.75
Spectroscopic studies on the interaction of fluorine containing triazole with bovine serum albumin. Biol Trace Elem Res (2010) 0.75
[Value of CODEHOP RT-pCR in detection of Flavivirus]. Bing Du Xue Bao (2014) 0.75
[New type of cytoplasmic polyhedrosis virus isolated from mosquitoes in China]. Bing Du Xue Bao (2008) 0.75
Microbial photoelectrotrophic denitrification as a sustainable and efficient way for reducing nitrate to nitrogen. Environ Sci Technol (2017) 0.75
[Analysis of microbial community structure in lactic acid fermentation from kitchen waste]. Huan Jing Ke Xue (2012) 0.75