Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women.
|
Science
|
2010
|
35.19
|
2
|
The impact of migration on HIV-1 transmission in South Africa: a study of migrant and nonmigrant men and their partners.
|
Sex Transm Dis
|
2003
|
5.09
|
3
|
The neutralization breadth of HIV-1 develops incrementally over four years and is associated with CD4+ T cell decline and high viral load during acute infection.
|
J Virol
|
2011
|
4.18
|
4
|
Health in South Africa: changes and challenges since 2009.
|
Lancet
|
2012
|
3.44
|
5
|
Establishing a cohort at high risk of HIV infection in South Africa: challenges and experiences of the CAPRISA 002 acute infection study.
|
PLoS One
|
2008
|
3.40
|
6
|
Achieving the health Millennium Development Goals for South Africa: challenges and priorities.
|
Lancet
|
2009
|
3.35
|
7
|
Limited neutralizing antibody specificities drive neutralization escape in early HIV-1 subtype C infection.
|
PLoS Pathog
|
2009
|
2.70
|
8
|
Stabilizing HIV prevalence masks high HIV incidence rates amongst rural and urban women in KwaZulu-Natal, South Africa.
|
Int J Epidemiol
|
2010
|
2.53
|
9
|
Evolution of an HIV glycan-dependent broadly neutralizing antibody epitope through immune escape.
|
Nat Med
|
2012
|
2.48
|
10
|
Symptomatic vaginal discharge is a poor predictor of sexually transmitted infections and genital tract inflammation in high-risk women in South Africa.
|
J Infect Dis
|
2012
|
2.42
|
11
|
Microbicides & their implications in HIV prevention.
|
Indian J Med Res
|
2010
|
2.36
|
12
|
The c3-v4 region is a major target of autologous neutralizing antibodies in human immunodeficiency virus type 1 subtype C infection.
|
J Virol
|
2007
|
2.29
|
13
|
Potent and broad neutralization of HIV-1 subtype C by plasma antibodies targeting a quaternary epitope including residues in the V2 loop.
|
J Virol
|
2011
|
2.26
|
14
|
The acceptability of an investigational vaginal microbicide, PRO 2000 Gel, among women in a phase I clinical trial.
|
J Womens Health (Larchmt)
|
2003
|
2.03
|
15
|
Isolation of a human anti-HIV gp41 membrane proximal region neutralizing antibody by antigen-specific single B cell sorting.
|
PLoS One
|
2011
|
1.99
|
16
|
Broad neutralization of human immunodeficiency virus type 1 mediated by plasma antibodies against the gp41 membrane proximal external region.
|
J Virol
|
2009
|
1.78
|
17
|
Innate immune activation enhances hiv acquisition in women, diminishing the effectiveness of tenofovir microbicide gel.
|
J Infect Dis
|
2012
|
1.73
|
18
|
Viral escape from HIV-1 neutralizing antibodies drives increased plasma neutralization breadth through sequential recognition of multiple epitopes and immunotypes.
|
PLoS Pathog
|
2013
|
1.65
|
19
|
Epidemiological impact of tenofovir gel on the HIV epidemic in South Africa.
|
J Acquir Immune Defic Syndr
|
2011
|
1.31
|
20
|
Safety and trough concentrations of nevirapine prophylaxis given daily, twice weekly, or weekly in breast-feeding infants from birth to 6 months.
|
J Acquir Immune Defic Syndr
|
2003
|
1.30
|
21
|
HIV incidence in young girls in KwaZulu-Natal, South Africa--public health imperative for their inclusion in HIV biomedical intervention trials.
|
AIDS Behav
|
2012
|
1.26
|
22
|
Genital tract inflammation during early HIV-1 infection predicts higher plasma viral load set point in women.
|
J Infect Dis
|
2012
|
1.17
|
23
|
Multiple pathways of escape from HIV broadly cross-neutralizing V2-dependent antibodies.
|
J Virol
|
2013
|
1.13
|
24
|
Ratio of monocytes to lymphocytes in peripheral blood identifies adults at risk of incident tuberculosis among HIV-infected adults initiating antiretroviral therapy.
|
J Infect Dis
|
2013
|
1.12
|
25
|
The future role of rectal and vaginal microbicides to prevent HIV infection in heterosexual populations: implications for product development and prevention.
|
Sex Transm Infect
|
2011
|
1.10
|
26
|
Disclosure of microbicide gel use to sexual partners: influence on adherence in the CAPRISA 004 trial.
|
AIDS Behav
|
2014
|
1.09
|
27
|
APOBEC3G expression is dysregulated in primary HIV-1 infection and polymorphic variants influence CD4+ T-cell counts and plasma viral load.
|
AIDS
|
2010
|
1.08
|
28
|
Adherence in the CAPRISA 004 tenofovir gel microbicide trial.
|
AIDS Behav
|
2014
|
1.06
|
29
|
HIV prevalence among high school learners - opportunities for schools-based HIV testing programmes and sexual reproductive health services.
|
BMC Public Health
|
2012
|
1.04
|
30
|
Modeling the impact of a partially effective HIV vaccine on HIV infection and death among women and infants in South Africa.
|
J Acquir Immune Defic Syndr
|
2006
|
1.03
|
31
|
The influence of tuberculosis treatment on efavirenz clearance in patients co-infected with HIV and tuberculosis.
|
Eur J Clin Pharmacol
|
2011
|
0.98
|
32
|
Association of polymorphisms in the LEDGF/p75 gene (PSIP1) with susceptibility to HIV-1 infection and disease progression.
|
AIDS
|
2011
|
0.97
|
33
|
Natural killer cell function in women at high risk for HIV acquisition: insights from a microbicide trial.
|
AIDS
|
2012
|
0.96
|
34
|
Anaemia in acute HIV-1 subtype C infection.
|
PLoS One
|
2008
|
0.96
|
35
|
Bacterial vaginosis and the risk of trichomonas vaginalis acquisition among HIV-1-negative women.
|
Sex Transm Dis
|
2014
|
0.96
|
36
|
Diagnostic Accuracy of the Point-of-Care Xpert HIV-1 Viral Load Assay in a South African HIV Clinic.
|
J Acquir Immune Defic Syndr
|
2016
|
0.96
|
37
|
When to start antiretroviral therapy during tuberculosis treatment?
|
Curr Opin Infect Dis
|
2013
|
0.94
|
38
|
Genital Tenofovir Concentrations Correlate With Protection Against HIV Infection in the CAPRISA 004 Trial: Importance of Adherence for Microbicide Effectiveness.
|
J Acquir Immune Defic Syndr
|
2015
|
0.93
|
39
|
Results of effectiveness trials of PRO 2000 gel: lessons for future microbicide trials.
|
Future Microbiol
|
2010
|
0.93
|
40
|
Differential impact of magnitude, polyfunctional capacity, and specificity of HIV-specific CD8+ T cell responses on HIV set point.
|
J Virol
|
2013
|
0.92
|
41
|
Mucosal Escherichia coli bactericidal activity and immune mediators are associated with HIV-1 seroconversion in women participating in the HPTN 035 trial.
|
J Infect Dis
|
2012
|
0.92
|
42
|
Antiretroviral therapy: challenges and options in South Africa.
|
Lancet
|
2003
|
0.91
|
43
|
Incidence of Sexually Transmitted Infections among HIV-positive sex workers in KwaZulu-Natal, South Africa.
|
Sex Transm Dis
|
2002
|
0.89
|
44
|
Y chromosome and HIV DNA detection in vaginal swabs as biomarkers of semen and HIV exposure in women.
|
Sex Transm Dis
|
2014
|
0.88
|
45
|
Treatment of maternal syphilis in rural South Africa: effect of multiple doses of benzathine penicillin on pregnancy loss.
|
Trop Med Int Health
|
2004
|
0.87
|
46
|
Limited HIV-1 superinfection in seroconverters from the CAPRISA 004 Microbicide Trial.
|
J Clin Microbiol
|
2013
|
0.87
|
47
|
The preventive misconception: experiences from CAPRISA 004.
|
AIDS Behav
|
2014
|
0.86
|
48
|
Risk Factors for HIV Acquisition in High Risk Women in a Generalised Epidemic Setting.
|
AIDS Behav
|
2015
|
0.85
|
49
|
An AIDS-free generation?
|
Science
|
2012
|
0.85
|
50
|
The SAPIT trial provides essential evidence on risks and benefits of integrated and sequential treatment of HIV and tuberculosis.
|
S Afr Med J
|
2010
|
0.85
|
51
|
Trends in HIV Prevalence in Pregnant Women in Rural South Africa.
|
J Acquir Immune Defic Syndr
|
2015
|
0.84
|
52
|
Assessing the implementation effectiveness and safety of 1% tenofovir gel provision through family planning services in KwaZulu-Natal, South Africa: study protocol for an open-label randomized controlled trial.
|
Trials
|
2014
|
0.83
|
53
|
Neither microbial translocation nor TLR responsiveness are likely explanations for preexisting immune activation in women who subsequently acquired HIV in CAPRISA 004.
|
J Acquir Immune Defic Syndr
|
2013
|
0.83
|
54
|
A drug evaluation of 1% tenofovir gel and tenofovir disoproxil fumarate tablets for the prevention of HIV infection.
|
Expert Opin Investig Drugs
|
2012
|
0.82
|
55
|
Design challenges facing clinical trials of the effectiveness of new HIV-prevention technologies.
|
AIDS
|
2012
|
0.82
|
56
|
Recombination-mediated escape from primary CD8+ T cells in acute HIV-1 infection.
|
Retrovirology
|
2014
|
0.82
|
57
|
Health-related quality of life dynamics of HIV-positive South African women up to ART initiation: evidence from the CAPRISA 002 acute infection cohort study.
|
AIDS Behav
|
2014
|
0.82
|
58
|
Impact of antiretroviral therapy on health-related quality of life among South African women in the CAPRISA 002 acute infection study.
|
AIDS Behav
|
2014
|
0.79
|
59
|
Monitoring microbicide gel use with real-time notification of the container's opening events: results of the CAPRISA Wisebag study.
|
AIDS Behav
|
2014
|
0.79
|
60
|
Diverse approaches useful for microbicide trials.
|
Nature
|
2007
|
0.79
|
61
|
Individualised motivational counselling to enhance adherence to antiretroviral therapy is not superior to didactic counselling in South African patients: findings of the CAPRISA 058 randomised controlled trial.
|
AIDS Behav
|
2015
|
0.79
|
62
|
Efavirenz dosing: influence of drug metabolizing enzyme polymorphisms and concurrent tuberculosis treatment.
|
Antivir Ther
|
2015
|
0.78
|
63
|
TRIM5α and TRIM22 are differentially regulated according to HIV-1 infection phase and compartment.
|
J Virol
|
2014
|
0.78
|
64
|
HIV-positive status disclosure in patients in care in rural South Africa: implications for scaling up treatment and prevention interventions.
|
AIDS Behav
|
2015
|
0.78
|
65
|
High rates of tuberculosis in patients accessing HAART in rural South Africa.
|
J Acquir Immune Defic Syndr
|
2014
|
0.77
|
66
|
Low rifampicin concentrations in tuberculosis patients with HIV infection.
|
J Infect Dev Ctries
|
2014
|
0.77
|
67
|
Metabolic Syndrome After HIV Acquisition in South African Women.
|
J Acquir Immune Defic Syndr
|
2016
|
0.77
|
68
|
Top stories of 2008. The prospect of PrEP.
|
AIDS Clin Care
|
2009
|
0.77
|
69
|
An adaptive design to bridge the gap between Phase 2b/3 microbicide effectiveness trials and evidence required for licensure.
|
Clin Trials
|
2012
|
0.77
|
70
|
Ritonavir/saquinavir safety concerns curtail antiretroviral therapy options for tuberculosis-HIV-co-infected patients in resource-constrained settings.
|
AIDS
|
2006
|
0.76
|
71
|
Tenofovir Gel to Prevent HSV-2 Infection.
|
N Engl J Med
|
2015
|
0.75
|
72
|
Genital-Systemic Chemokine Gradients and the Risk of HIV Acquisition in Women.
|
J Acquir Immune Defic Syndr
|
2017
|
0.75
|
73
|
Safety of coitally administered tenofovir 1% gel, a vaginal microbicide, in chronic hepatitis B virus carriers: results from the CAPRISA 004 trial.
|
Antiviral Res
|
2013
|
0.75
|
74
|
Association of Polymorphisms in the Regulatory Region of the Cyclophilin a Gene (PPIA) with Gene Expression and HIV/AIDS Disease Progression.
|
J Acquir Immune Defic Syndr
|
2016
|
0.75
|
75
|
Report on the XIV International AIDS Conference.
|
AIDS Clin Care
|
2002
|
0.75
|
76
|
Genital - Systemic chemokine gradients and the risk of HIV acquisition in women.
|
J Acquir Immune Defic Syndr
|
2016
|
0.75
|
77
|
Update on pre-exposure prophylaxis.
|
J Watch AIDS Clin Care
|
2011
|
0.75
|
78
|
HIV vaccine and microbicide trials turn a corner. We still don't have an effective vaccine or microbicide for the clinic, but two major trials this year brought us closer than we've ever been.
|
J Watch AIDS Clin Care
|
2010
|
0.75
|
79
|
Challenging racial stereotyping of AIDS in South Africa with prevalence of HIV in pregnant women.
|
S Afr Med J
|
2007
|
0.75
|
80
|
TMP-SMX prophylaxis reduces mortality among African patients on ART.
|
J Watch AIDS Clin Care
|
2010
|
0.75
|
81
|
Top stories of 2004. DNA-MVA prime boost: another vaccine candidate bites the dust.
|
AIDS Clin Care
|
2005
|
0.75
|
82
|
ART and pregnancy rates.
|
J Watch AIDS Clin Care
|
2010
|
0.75
|
83
|
Antiretroviral pre-exposure prophylaxis; new hope and conundrums.
|
J Watch AIDS Clin Care
|
2012
|
0.75
|
84
|
Serum glycan-binding IgG antibodies in HIV-1 infection and during the development of broadly neutralizing responses.
|
AIDS
|
2017
|
0.75
|
85
|
Report from the XVI International AIDS Conference. SMART and DART: intermittent antiretroviral treatment is suboptimal and should be avoided.
|
AIDS Clin Care
|
2006
|
0.75
|
86
|
Meeting report from the XV International AIDS Conference. Prevention.
|
AIDS Clin Care
|
2004
|
0.75
|