Published in Mol Pharm on August 31, 2009
Lipid modified triblock PAMAM-based nanocarriers for siRNA drug co-delivery. Biomaterials (2012) 1.59
New strategies to deliver anticancer drugs to brain tumors. Expert Opin Drug Deliv (2009) 1.29
Nanomedicine: towards development of patient-friendly drug-delivery systems for oncological applications. Int J Nanomedicine (2012) 1.12
pH-sensitive poly(histidine)-PEG/DSPE-PEG co-polymer micelles for cytosolic drug delivery. Biomaterials (2012) 1.08
Accumulation and toxicity of antibody-targeted doxorubicin-loaded PEG-PE micelles in ovarian cancer cell spheroid model. J Control Release (2012) 1.04
Self-assembled Tat nanofibers as effective drug carrier and transporter. ACS Nano (2013) 1.00
Polymeric micelles containing reversibly phospholipid-modified anti-survivin siRNA: a promising strategy to overcome drug resistance in cancer. Cancer Lett (2013) 0.91
Enhanced tumor treatment using biofunctional indocyanine green-containing nanostructure by intratumoral or intravenous injection. Mol Pharm (2012) 0.89
Enabling anticancer therapeutics by nanoparticle carriers: the delivery of Paclitaxel. Int J Mol Sci (2011) 0.87
The effect of co-delivery of paclitaxel and curcumin by transferrin-targeted PEG-PE-based mixed micelles on resistant ovarian cancer in 3-D spheroids and in vivo tumors. Eur J Pharm Biopharm (2014) 0.87
1H NMR detection of mobile lipids as a marker for apoptosis: the case of anticancer drug-loaded liposomes and polymeric micelles. Mol Pharm (2009) 0.86
Preferential cellular uptake of amphiphilic macromolecule-lipid complexes with enhanced stability and biocompatibility. J Control Release (2011) 0.84
Quantum dot loaded immunomicelles for tumor imaging. BMC Med Imaging (2010) 0.81
Polymeric micelles: nanocarriers for cancer-targeted drug delivery. AAPS PharmSciTech (2014) 0.81
Manganese-loaded lipid-micellar theranostics for simultaneous drug and gene delivery to lungs. J Control Release (2013) 0.80
Dual-function theranostic nanoparticles for drug delivery and medical imaging contrast: perspectives and challenges for use in lung diseases. Drug Deliv Transl Res (2013) 0.78
Micellar and structural stability of nanoscale amphiphilic polymers: Implications for anti-atherosclerotic bioactivity. Biomaterials (2016) 0.75
TSPO expression in brain tumours: is TSPO a target for brain tumour imaging? Clin Transl Imaging (2016) 0.75
Telodendrimer-based nanocarriers for the treatment of ovarian cancer. Ther Deliv (2013) 0.75
Synthesis, characterization and radiolabeling of polymeric nano-micelles as a platform for tumor delivering. Biomed Pharmacother (2017) 0.75
Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. J Control Release (2000) 14.89
Micellar nanocarriers: pharmaceutical perspectives. Pharm Res (2006) 4.21
Hypersensitivity reactions from taxol. J Clin Oncol (1990) 3.83
Isolation of the mitochondrial benzodiazepine receptor: association with the voltage-dependent anion channel and the adenine nucleotide carrier. Proc Natl Acad Sci U S A (1992) 2.72
Recent approaches to intracellular delivery of drugs and DNA and organelle targeting. Annu Rev Biomed Eng (2006) 2.39
Targeted pharmaceutical nanocarriers for cancer therapy and imaging. AAPS J (2007) 2.38
Paclitaxel and its formulations. Int J Pharm (2002) 2.34
Immunomicelles: targeted pharmaceutical carriers for poorly soluble drugs. Proc Natl Acad Sci U S A (2003) 2.28
Polymeric micelles - a new generation of colloidal drug carriers. Eur J Pharm Biopharm (1999) 2.18
Micelles from lipid derivatives of water-soluble polymers as delivery systems for poorly soluble drugs. Adv Drug Deliv Rev (2004) 2.13
Peripheral benzodiazepine receptors and mitochondrial function. Neurochem Int (2002) 1.82
p-Nitrophenylcarbonyl-PEG-PE-liposomes: fast and simple attachment of specific ligands, including monoclonal antibodies, to distal ends of PEG chains via p-nitrophenylcarbonyl groups. Biochim Biophys Acta (2001) 1.82
Tumor-targeted liposomes: doxorubicin-loaded long-circulating liposomes modified with anti-cancer antibody. J Control Release (2004) 1.80
Folate receptor targeted biodegradable polymeric doxorubicin micelles. J Control Release (2004) 1.71
Targeted disruption of the peripheral-type benzodiazepine receptor gene inhibits steroidogenesis in the R2C Leydig tumor cell line. J Biol Chem (1997) 1.40
Preparation and characterization of the micelle-forming polymeric drug indomethacin-incorporated poly(ethylene oxide)-poly(beta-benzyl L-aspartate) block copolymer micelles. J Pharm Sci (1996) 1.38
Complement activation by Cremophor EL as a possible contributor to hypersensitivity to paclitaxel: an in vitro study. J Natl Cancer Inst (1998) 1.32
Hydrotropic agents for study of in vitro paclitaxel release from polymeric micelles. J Control Release (2004) 1.31
Peripheral-type benzodiazepine receptors: autoradiographic localization in whole-body sections of neonatal rats. J Pharmacol Exp Ther (1985) 1.29
Polyethylene glycol-phosphatidylethanolamine conjugate (PEG-PE)-based mixed micelles: some properties, loading with paclitaxel, and modulation of P-glycoprotein-mediated efflux. Int J Pharm (2006) 1.17
Synthesis and evaluation of some water-soluble prodrugs and derivatives of taxol with antitumor activity. J Med Chem (1992) 1.16
Fluorescence microscopy to follow the targeting of liposomes and micelles to cells and their intracellular fate. Adv Drug Deliv Rev (2005) 1.06
Micelles from polyethylene glycol/phosphatidylethanolamine conjugates for tumor drug delivery. J Control Release (2003) 1.03
Up-regulation of the peripheral benzodiazepine receptor during human colorectal carcinogenesis and tumor spread. Clin Cancer Res (2005) 0.95
Peripheral benzodiazepine receptor ligands: mitochondrial transmembrane potential depolarization and apoptosis induction in rat C6 glioma cells. Biochem Pharmacol (2004) 0.95
Peripheral-type benzodiazepine receptor density and in vitro tumorigenicity of glioma cell lines. Biochem Pharmacol (2004) 0.92
Peripheral benzodiazepine receptor (PBR) ligand cytotoxicity unrelated to PBR expression. Biochem Pharmacol (2005) 0.87
Peripheral benzodiazepine receptor and its clinical targeting. Anticancer Drugs (2004) 0.83
Structure-activity relationships and effects on neuroactive steroid synthesis in a series of 2-phenylimidazo[1,2-a]pyridineacetamide peripheral benzodiazepine receptors ligands. J Med Chem (2005) 0.82
Synthesis and antitumor activity of peptide-paclitaxel conjugates. J Pept Sci (2007) 0.81
Novel 2-phenylimidazo[1,2-a]pyridine derivatives as potent and selective ligands for peripheral benzodiazepine receptors: synthesis, binding affinity, and in vivo studies. J Med Chem (1999) 0.79
Peripheral benzodiazepine receptor ligand-melphalan conjugates for potential selective drug delivery to brain tumors. Bioconjug Chem (2003) 0.78
Quantum dots spectrally distinguish multiple species within the tumor milieu in vivo. Nat Med (2005) 3.19
Micelles from lipid derivatives of water-soluble polymers as delivery systems for poorly soluble drugs. Adv Drug Deliv Rev (2004) 2.13
Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides. Adv Drug Deliv Rev (2004) 2.12
Cationic charge determines the distribution of liposomes between the vascular and extravascular compartments of tumors. Cancer Res (2002) 2.09
Matrix metalloprotease 2-responsive multifunctional liposomal nanocarrier for enhanced tumor targeting. ACS Nano (2012) 1.86
Tumor-targeted liposomes: doxorubicin-loaded long-circulating liposomes modified with anti-cancer antibody. J Control Release (2004) 1.80
Cell-penetrating peptides: breaking through to the other side. Trends Mol Med (2012) 1.68
Polyethylene glycol-diacyllipid micelles demonstrate increased acculumation in subcutaneous tumors in mice. Pharm Res (2002) 1.60
Lipid modified triblock PAMAM-based nanocarriers for siRNA drug co-delivery. Biomaterials (2012) 1.59
Liposome clearance in mice: the effect of a separate and combined presence of surface charge and polymer coating. Int J Pharm (2002) 1.58
Design, synthesis, and characterization of pH-sensitive PEG-PE conjugates for stimuli-sensitive pharmaceutical nanocarriers: the effect of substitutes at the hydrazone linkage on the ph stability of PEG-PE conjugates. Bioconjug Chem (2007) 1.43
Tumor-targeted nanomedicines: enhanced antitumor efficacy in vivo of doxorubicin-loaded, long-circulating liposomes modified with cancer-specific monoclonal antibody. Clin Cancer Res (2009) 1.35
New strategies to deliver anticancer drugs to brain tumors. Expert Opin Drug Deliv (2009) 1.29
Enhanced transfection of tumor cells in vivo using "Smart" pH-sensitive TAT-modified pegylated liposomes. J Drug Target (2007) 1.27
Multifunctional PEGylated 2C5-immunoliposomes containing pH-sensitive bonds and TAT peptide for enhanced tumor cell internalization and cytotoxicity. J Control Release (2011) 1.25
Self-assembling micelle-like nanoparticles based on phospholipid-polyethyleneimine conjugates for systemic gene delivery. J Control Release (2008) 1.22
Enhanced binding and killing of target tumor cells by drug-loaded liposomes modified with tumor-specific phage fusion coat protein. Nanomedicine (Lond) (2010) 1.21
Organelle-targeted nanocarriers: specific delivery of liposomal ceramide to mitochondria enhances its cytotoxicity in vitro and in vivo. Nano Lett (2008) 1.19
Radiofrequency thermal ablation sharply increases intratumoral liposomal doxorubicin accumulation and tumor coagulation. Cancer Res (2003) 1.19
Increased accumulation of PEG-PE micelles in the area of experimental myocardial infarction in rabbits. J Control Release (2004) 1.19
Liposomes targeted by fusion phage proteins. Nanomedicine (2008) 1.19
Polyethylene glycol-phosphatidylethanolamine conjugate (PEG-PE)-based mixed micelles: some properties, loading with paclitaxel, and modulation of P-glycoprotein-mediated efflux. Int J Pharm (2006) 1.17
Enhanced accumulation of long-circulating liposomes modified with the nucleosome-specific monoclonal antibody 2C5 in various tumours in mice: gamma-imaging studies. Eur J Nucl Med Mol Imaging (2006) 1.17
Paclitaxel-loaded polymeric micelles modified with MCF-7 cell-specific phage protein: enhanced binding to target cancer cells and increased cytotoxicity. Mol Pharm (2010) 1.17
Nanopreparations to overcome multidrug resistance in cancer. Adv Drug Deliv Rev (2013) 1.14
Enhanced cytotoxicity of monoclonal anticancer antibody 2C5-modified doxorubicin-loaded PEGylated liposomes against various tumor cell lines. Eur J Pharm Sci (2007) 1.14
P-glycoprotein silencing with siRNA delivered by DOPE-modified PEI overcomes doxorubicin resistance in breast cancer cells. Nanomedicine (Lond) (2012) 1.14
Design of multifunctional non-viral gene vectors to overcome physiological barriers: dilemmas and strategies. Int J Pharm (2011) 1.13
siRNA-containing liposomes modified with polyarginine effectively silence the targeted gene. J Control Release (2006) 1.12
Polymeric micelles for delivery of poorly soluble drugs: preparation and anticancer activity in vitro of paclitaxel incorporated into mixed micelles based on poly(ethylene glycol)-lipid conjugate and positively charged lipids. J Drug Target (2005) 1.12
Reversal of multidrug resistance by co-delivery of tariquidar (XR9576) and paclitaxel using long-circulating liposomes. Int J Pharm (2011) 1.12
Radio-frequency ablation increases intratumoral liposomal doxorubicin accumulation in a rat breast tumor model. Radiology (2002) 1.11
ATP-loaded liposomes effectively protect the myocardium in rabbits with an acute experimental myocardial infarction. Pharm Res (2005) 1.10
Recent developments in lipid-based pharmaceutical nanocarriers. Front Biosci (Landmark Ed) (2011) 1.09
Polyethyleneimine-lipid conjugate-based pH-sensitive micellar carrier for gene delivery. Biomaterials (2012) 1.09
"Smart" drug carriers: PEGylated TATp-modified pH-sensitive liposomes. J Liposome Res (2007) 1.09
pH-sensitive poly(histidine)-PEG/DSPE-PEG co-polymer micelles for cytosolic drug delivery. Biomaterials (2012) 1.08
Do liposomal apoptotic enhancers increase tumor coagulation and end-point survival in percutaneous radiofrequency ablation of tumors in a rat tumor model? Radiology (2010) 1.07
Liposomes loaded with paclitaxel and modified with novel triphenylphosphonium-PEG-PE conjugate possess low toxicity, target mitochondria and demonstrate enhanced antitumor effects in vitro and in vivo. J Control Release (2012) 1.06
Recent trends in multifunctional liposomal nanocarriers for enhanced tumor targeting. J Drug Deliv (2013) 1.06
Antinucleosome antibody-modified liposomes and lipid-core micelles for tumor-targeted delivery of therapeutic and diagnostic agents. J Liposome Res (2007) 1.05
Synergy of photoacoustic and fluorescence flow cytometry of circulating cells with negative and positive contrasts. J Biophotonics (2012) 1.05
Current trends in liposome research. Methods Mol Biol (2010) 1.05
Poly(malic acid) nanoconjugates containing various antibodies and oligonucleotides for multitargeting drug delivery. Nanomedicine (Lond) (2008) 1.04
Accumulation and toxicity of antibody-targeted doxorubicin-loaded PEG-PE micelles in ovarian cancer cell spheroid model. J Control Release (2012) 1.04
Challenges in development of targeted liposomal therapeutics. AAPS J (2012) 1.03
Micelles from polyethylene glycol/phosphatidylethanolamine conjugates for tumor drug delivery. J Control Release (2003) 1.03
Tumor-specific antibody-mediated targeted delivery of Doxil reduces the manifestation of auricular erythema side effect in mice. Int J Pharm (2008) 1.03
Mixed PEG-PE/vitamin E tumor-targeted immunomicelles as carriers for poorly soluble anti-cancer drugs: improved drug solubilization and enhanced in vitro cytotoxicity. Eur J Pharm Biopharm (2008) 1.02
Combination radiofrequency ablation with intratumoral liposomal doxorubicin: effect on drug accumulation and coagulation in multiple tissues and tumor types in animals. Radiology (2005) 1.02
Monoclonal antibody 2C5-modified doxorubicin-loaded liposomes with significantly enhanced therapeutic activity against intracranial human brain U-87 MG tumor xenografts in nude mice. Cancer Immunol Immunother (2007) 1.00
Cationic liposomes loaded with proapoptotic peptide D-(KLAKLAK)(2) and Bcl-2 antisense oligodeoxynucleotide G3139 for enhanced anticancer therapy. Mol Pharm (2009) 1.00
Landscape phage fusion protein-mediated targeting of nanomedicines enhances their prostate tumor cell association and cytotoxic efficiency. Nanomedicine (2010) 1.00
Cancer cell spheroids as a model to evaluate chemotherapy protocols. Cancer Biol Ther (2012) 0.99
Delivery of siRNA into breast cancer cells via phage fusion protein-targeted liposomes. Nanomedicine (2010) 0.99
Enhanced anticancer activity of nanopreparation containing an MMP2-sensitive PEG-drug conjugate and cell-penetrating moiety. Proc Natl Acad Sci U S A (2013) 0.99
2-Phenyl-imidazo[1,2-a]pyridine compounds containing hydrophilic groups as potent and selective ligands for peripheral benzodiazepine receptors: synthesis, binding affinity and electrophysiological studies. J Med Chem (2008) 0.99
Environment-responsive multifunctional liposomes. Methods Mol Biol (2010) 0.99
Cytoplasmic delivery of liposomes into MCF-7 breast cancer cells mediated by cell-specific phage fusion coat protein. Mol Pharm (2010) 0.98
Recent advances in medicinal chemistry and pharmaceutical technology--strategies for drug delivery to the brain. Curr Top Med Chem (2009) 0.97
Enhanced in vivo antitumor efficacy of poorly soluble PDT agent, meso-tetraphenylporphine, in PEG-PE-based tumor-targeted immunomicelles. Cancer Biol Ther (2007) 0.97
Enhanced cytotoxicity of TATp-bearing paclitaxel-loaded micelles in vitro and in vivo. Int J Pharm (2009) 0.96
Efficient intracellular drug-targeting of macrophages using stealth liposomes directed to the hemoglobin scavenger receptor CD163. J Control Release (2012) 0.95
Surface modification of liposomes with rhodamine-123-conjugated polymer results in enhanced mitochondrial targeting. J Drug Target (2011) 0.95
TAT peptide and its conjugates: proteolytic stability. Bioconjug Chem (2009) 0.95
Effective stabilization and delivery of siRNA: reversible siRNA-phospholipid conjugate in nanosized mixed polymeric micelles. Bioconjug Chem (2010) 0.95
TAT peptide-modified liposomes provide enhanced gene delivery to intracranial human brain tumor xenografts in nude mice. Oncol Res (2007) 0.94
DQAsome-mediated delivery of plasmid DNA toward mitochondria in living cells. J Control Release (2003) 0.94
Polymeric micelles: polyethylene glycol-phosphatidylethanolamine (PEG-PE)-based micelles as an example. Methods Mol Biol (2010) 0.94
Surface conjugation of triphenylphosphonium to target poly(amidoamine) dendrimers to mitochondria. Biomaterials (2012) 0.94
Cell-penetrating TAT peptide in drug delivery systems: proteolytic stability requirements. Drug Deliv (2011) 0.93
Octa-arginine-modified pegylated liposomal doxorubicin: an effective treatment strategy for non-small cell lung cancer. Cancer Lett (2013) 0.93
Proteomic analysis of serum opsonins impacting biodistribution and cellular association of porous silicon microparticles. Mol Imaging (2011) 0.92
Tat peptide-mediated intracellular delivery of liposomes. Methods Enzymol (2003) 0.92
Mitochondriotropic liposomes. J Liposome Res (2005) 0.92
Phospholipid-polyethylenimine conjugate-based micelle-like nanoparticles for siRNA delivery. Drug Deliv Transl Res (2011) 0.92
Mitochondria-targeted liposomes improve the apoptotic and cytotoxic action of sclareol. J Liposome Res (2010) 0.92
Stimulus-responsive nanopreparations for tumor targeting. Integr Biol (Camb) (2013) 0.91
Comparative effects of some hydrophilic excipients on the rate of gabapentin and baclofen lactamization in lyophilized formulations. Int J Pharm (2006) 0.91
siRNA delivery: from basics to therapeutic applications. Front Biosci (Landmark Ed) (2013) 0.91
Alpidem analogues containing a GABA or glycine moiety as new anticonvulsant agents. Eur J Pharm Sci (2003) 0.91
Platinum(II) complexes with bioactive carrier ligands having high affinity for the translocator protein. J Med Chem (2010) 0.90
Nanocarriers. Pharm Res (2007) 0.90
Recent advances in ligand targeted therapy. J Drug Target (2011) 0.90
Peripheral benzodiazepine receptor ligand-PLGA polymer conjugates potentially useful as delivery systems of apoptotic agents. J Control Release (2009) 0.90
In vitro targeting and imaging the translocator protein TSPO 18-kDa through G(4)-PAMAM-FITC labeled dendrimer. J Control Release (2013) 0.89
Tumor-specific anti-nucleosome antibody improves therapeutic efficacy of doxorubicin-loaded long-circulating liposomes against primary and metastatic tumor in mice. Mol Pharm (2009) 0.89
In vitro optimization of liposomal nanocarriers prepared from breast tumor cell specific phage fusion protein. J Drug Target (2011) 0.89
Enhanced tumor MR imaging with gadolinium-loaded polychelating polymer-containing tumor-targeted liposomes. J Magn Reson Imaging (2008) 0.88
Protective effect of coenzyme Q10-loaded liposomes on the myocardium in rabbits with an acute experimental myocardial infarction. Pharm Res (2007) 0.88
Improved transfection of spleen-derived antigen-presenting cells in culture using TATp-liposomes. J Control Release (2008) 0.88
Eudragit RS 100 microparticles containing 2-hydroxypropyl-beta-cyclodextrin and glutathione: physicochemical characterization, drug release and transport studies. Eur J Pharm Sci (2006) 0.88