Published in Am J Med Genet A on October 01, 2009
Effects and safety of periconceptional folate supplementation for preventing birth defects. Cochrane Database Syst Rev (2010) 2.31
Lack of maternal folic acid supplementation is associated with heart defects in Down syndrome: a report from the National Down Syndrome Project. Birth Defects Res A Clin Mol Teratol (2011) 0.87
Polymorphisms in folate-metabolizing genes, chromosome damage, and risk of Down syndrome in Italian women: identification of key factors using artificial neural networks. BMC Med Genomics (2010) 0.84
Methylenetetrahydrofolate reductase polymorphism is not risk factor for Down syndrome in North India. Indian J Hum Genet (2014) 0.83
The association of the MTHFR c.1625A>C genetic variant with the risk of congenital heart diseases in the Chinese. Genet Test Mol Biomarkers (2015) 0.81
Incidence of down syndrome: Hypotheses and reality. Indian J Hum Genet (2011) 0.77
Maternal methylenetetrahydrofolate reductase C677T polymorphism and down syndrome risk: a meta-analysis from 34 studies. PLoS One (2014) 0.77
The genetics of folate metabolism and maternal risk of birth of a child with Down syndrome and associated congenital heart defects. Front Genet (2015) 0.75
Methylenetetrahydrofolatereductase C677T polymorphism and folate metabolism in human health. Indian J Hum Genet (2014) 0.75
Evaluation of homocysteine levels in individuals having nonsyndromic cleft lip with or without palate. J Oral Maxillofac Pathol (2016) 0.75
Familial history of type 2 diabetes in patients from Southern Brazil and its influence on the clinical characteristics of this disease. Arq Bras Endocrinol Metabol (2006) 1.60
Detection of R337H, a germline TP53 mutation predisposing to multiple cancers, in asymptomatic women participating in a breast cancer screening program in Southern Brazil. Cancer Lett (2008) 1.44
Population prevalence of hereditary breast cancer phenotypes and implementation of a genetic cancer risk assessment program in southern Brazil. Genet Mol Biol (2009) 1.08
Fetal safety of loratadine use in the first trimester of pregnancy: a multicenter study. J Allergy Clin Immunol (2003) 1.03
Functional vascular endothelial growth factor -634G>C SNP is associated with proliferative diabetic retinopathy: a case-control study in a Brazilian population of European ancestry. Diabetes Care (2007) 1.02
The -374A allele of the receptor for advanced glycation end products gene is associated with a decreased risk of ischemic heart disease in African-Brazilians with type 2 diabetes. Mol Genet Metab (2005) 0.96
Epidemiological surveillance of birth defects compatible with thalidomide embryopathy in Brazil. PLoS One (2011) 0.95
Diabetic retinopathy in Euro-Brazilian type 2 diabetic patients: relationship with polymorphisms in the aldose reductase, the plasminogen activator inhibitor-1 and the methylenetetrahydrofolate reductase genes. Diabetes Res Clin Pract (2003) 0.94
[Prevalence of micro and macroangiopatic chronic complications and their risk factors in the care of out patients with type 2 diabetes mellitus]. Rev Assoc Med Bras (2004) 0.91
Von Willebrand factor in colorectal cancer. Int J Colorectal Dis (2002) 0.88
Recognition of the phenotype of thalidomide embryopathy in countries endemic for leprosy: new cases and review of the main dysmorphological findings. Clin Dysmorphol (2013) 0.87
Influence of genetic, biological and pharmacological factors on warfarin dose in a Southern Brazilian population of European ancestry. Br J Clin Pharmacol (2011) 0.87
Relationship of endothelial nitric oxide synthase (eNOS) gene polymorphisms with diabetic retinopathy in Caucasians with type 2 diabetes. Ophthalmic Genet (2011) 0.86
Atypical macrocephaly-cutis marmorata telangiectatica congenita with retinoblastoma. Clin Dysmorphol (2002) 0.85
The -106CC genotype of the aldose reductase gene is associated with an increased risk of proliferative diabetic retinopathy in Caucasian-Brazilians with type 2 diabetes. Mol Genet Metab (2006) 0.85
Portal vein thrombosis in children and adolescents: the low prevalence of hereditary thrombophilic disorders. J Pediatr Surg (2004) 0.83
Immunogenetics of pregnancy: role of a 14-bp deletion in the maternal HLA-G gene in primiparous pre-eclamptic Brazilian women. Hum Immunol (2007) 0.83
Risk factors for hypertensive disorders of pregnancy in southern Brazil. Rev Assoc Med Bras (2012) 0.83
The catalase -262C/T promoter polymorphism and diabetic complications in Caucasians with type 2 diabetes. Dis Markers (2006) 0.82
Maternal gene polymorphisms involved in folate metabolism as risk factors for Down syndrome offspring in Southern Brazil. Dis Markers (2010) 0.81
Prevalence of 15 mitochondrial DNA mutations among type 2 diabetic patients with or without clinical characteristics of maternally inherited diabetes and deafness. Arq Bras Endocrinol Metabol (2008) 0.81
Association between mannose-binding lectin gene polymorphisms and pre-eclampsia in Brazilian women. Am J Reprod Immunol (2010) 0.81
Plasma von Willebrand factor levels correlate with clinical outcome of severe traumatic brain injury. J Neurotrauma (2007) 0.80
Susceptibility to DNA damage in workers occupationally exposed to pesticides, to tannery chemicals and to coal dust during mining. Genet Mol Biol (2012) 0.79
Association of eNOS gene polymorphisms with renal disease in Caucasians with type 2 diabetes. Diabetes Res Clin Pract (2011) 0.79
MTHFR C677T is not a risk factor for autism spectrum disorders in South Brazil. Psychiatr Genet (2010) 0.78
Prenatal alcohol exposure as a risk factor for dysfunctional behaviors: the role of the pediatrician. J Pediatr (Rio J) (2008) 0.78
MSX1 and PAX9 investigation in monozygotic twins with variable expression of tooth agenesis. Twin Res Hum Genet (2013) 0.78
Influence of VKORC1 gene polymorphisms on the effect of oral vitamin K supplementation in over-anticoagulated patients. J Thromb Thrombolysis (2014) 0.78
The effect of ABO blood group on von Willebrand response to exercise. Clin Appl Thromb Hemost (2007) 0.78
Reproductive risk factors related to socioeconomic status in pregnant women in southern Brazil. Community Genet (2003) 0.77
Relationship of p22phox C242T polymorphism with nephropathy in type 2 diabetic patients. J Nephrol (2005) 0.77
Dipyrone use during pregnancy and adverse perinatal events. Arch Gynecol Obstet (2008) 0.77
Maternal drinking behavior and Fetal Alcohol Spectrum Disorders in adolescents with criminal behavior in southern Brazil. Genet Mol Biol (2012) 0.76
Frequency and clinical profile of patients with polycystic kidney disease in southern Brazil. Ren Fail (2008) 0.76
A DNA repair variant in POLQ (c.-1060A > G) is associated to hereditary breast cancer patients: a case-control study. BMC Cancer (2014) 0.76
Influence of the 5-HTTLPR polymorphism and environmental risk factors in a Brazilian sample of patients with autism spectrum disorders. Brain Res (2009) 0.76
[Thrombophilic disorders in children and adolescents with portal vein thrombosis]. J Pediatr (Rio J) (2003) 0.75
Genetic changes in severe haemophilia A: new contribution to the aetiology of a complex disease. Blood Coagul Fibrinolysis (2013) 0.75
So close, so far away: analysis of surnames in a town of twins (Cândido Godói, Brazil). Ann Hum Genet (2013) 0.75
[Evaluation of the teratogenic risks in gestations exposed to misoprostol]. Rev Bras Ginecol Obstet (2010) 0.75
PPARA gene and phenprocoumon: a new predictor of response variability. Pharmacogenet Genomics (2015) 0.75
Analysis of the -1185A/G von Willebrand factor (VWF) gene polymorphism in two Brazilian ethnic groups and its effect on the plasma VWF levels. Thromb Res (2002) 0.75
Lack of association between thrombophilic gene variants and recurrent pregnancy loss. Hum Fertil (Camb) (2014) 0.75
Adult polycystic kidney disease in patients on haemodialysis in the south of Brazil. Nephrol Dial Transplant (2003) 0.75
Factor VIII mutations and inhibitor formation in a southern Brazilian population. Blood Coagul Fibrinolysis (2014) 0.75
A new algorithm for weekly phenprocoumon dose variation in a southern Brazilian population: role for CYP2C9, CYP3A4/5 and VKORC1 genes polymorphisms. Basic Clin Pharmacol Toxicol (2013) 0.75
Community diagnosis of maternal exposure to risk factors for congenital defects. Community Genet (2003) 0.75