Published in Int J Cancer on March 01, 2010
Eph receptors and ephrins in cancer: bidirectional signalling and beyond. Nat Rev Cancer (2010) 5.26
Radiogenomic mapping of edema/cellular invasion MRI-phenotypes in glioblastoma multiforme. PLoS One (2011) 2.35
Acute and fractionated irradiation differentially modulate glioma stem cell division kinetics. Cancer Res (2012) 1.25
EphB2 receptor controls proliferation/migration dichotomy of glioblastoma by interacting with focal adhesion kinase. Oncogene (2012) 1.12
Ephrin-B2 regulates endothelial cell morphology and motility independently of Eph-receptor binding. J Cell Sci (2010) 1.11
Novel cryo-imaging of the glioma tumor microenvironment reveals migration and dispersal pathways in vivid three-dimensional detail. Cancer Res (2011) 1.04
Clinical relevance of Ephs and ephrins in cancer: lessons from breast, colorectal, and lung cancer profiling. Semin Cell Dev Biol (2011) 1.00
Role of Eph/ephrin tyrosine kinase in malignant glioma. Neuro Oncol (2011) 0.90
Integrin α3 is overexpressed in glioma stem-like cells and promotes invasion. Br J Cancer (2013) 0.89
Eph receptors as therapeutic targets in glioblastoma. Br J Cancer (2014) 0.88
EphB2 activation is required for ependymoma development as well as inhibits differentiation and promotes proliferation of the transformed cell. Sci Rep (2015) 0.84
Prediction of functional phosphorylation sites by incorporating evolutionary information. Protein Cell (2012) 0.84
The future role of personalized medicine in the treatment of glioblastoma multiforme. Pharmgenomics Pers Med (2010) 0.83
Regulatory System for Stem/Progenitor Cell Niches in the Adult Rodent Pituitary. Int J Mol Sci (2016) 0.82
TNF-α/NF-κB signaling in the CNS: possible connection to EPHB2. J Neuroimmune Pharmacol (2013) 0.81
Ligand-dependent EphB1 signaling suppresses glioma invasion and correlates with patient survival. Neuro Oncol (2013) 0.80
EphrinB2 drives perivascular invasion and proliferation of glioblastoma stem-like cells. Elife (2016) 0.78
Novel strategy for selection of monoclonal antibodies against highly conserved antigens: phage library panning against ephrin-B2 displayed on yeast. PLoS One (2012) 0.77
Characterization of a third generation lentiviral vector pseudotyped with Nipah virus envelope proteins for endothelial cell transduction. Gene Ther (2013) 0.77
Ephs and Ephrins in malignant gliomas. Growth Factors (2014) 0.76
New insights into the functional consequences of ephrin A3 mutations in non-small cell lung cancer. Transl Lung Cancer Res (2013) 0.75
Paradoxes of the EphB1 receptor in malignant brain tumors. Cancer Cell Int (2017) 0.75
EMT Involved in Migration of Stem/Progenitor Cells for Pituitary Development and Regeneration. J Clin Med (2016) 0.75
The Chemokine Receptor CXCR6 Evokes Reverse Signaling via the Transmembrane Chemokine CXCL16. Int J Mol Sci (2017) 0.75
The WHO classification of tumors of the nervous system. J Neuropathol Exp Neurol (2002) 8.62
Eph-ephrin bidirectional signaling in physiology and disease. Cell (2008) 7.12
Mechanisms and functions of Eph and ephrin signalling. Nat Rev Mol Cell Biol (2002) 6.92
Cost of migration: invasion of malignant gliomas and implications for treatment. J Clin Oncol (2003) 5.28
Molecular mechanisms of glioma cell migration and invasion. J Neurooncol (2004) 3.04
Targeted molecular therapy of GBM. Brain Pathol (2003) 3.02
Rac-dependent trans-endocytosis of ephrinBs regulates Eph-ephrin contact repulsion. Nat Cell Biol (2003) 2.79
Molecular targets of glioma invasion. Cell Mol Life Sci (2007) 2.66
Gene expression profile of glioblastoma multiforme invasive phenotype points to new therapeutic targets. Neoplasia (2005) 2.37
Cell migration and invasion assays. Methods (2005) 2.32
Regulation of metastases by signal transducer and activator of transcription 3 signaling pathway: clinical implications. Clin Cancer Res (2007) 2.06
Receptor tyrosine kinase EphB4 is a survival factor in breast cancer. Am J Pathol (2006) 1.83
Signal transducer and activator of transcription-3: a molecular hub for signaling pathways in gliomas. Mol Cancer Res (2008) 1.80
Coexpression of EphB4 and ephrinB2 in tumour advancement of ovarian cancers. Br J Cancer (2008) 1.58
Eph receptor and ephrin ligand-mediated interactions during angiogenesis and tumor progression. Exp Cell Res (2005) 1.57
Overexpression of ERK, an EPH family receptor protein tyrosine kinase, in various human tumors. Cancer Res (1994) 1.55
Eph-ephrin signalling in adult tissues and cancer. Curr Opin Cell Biol (2008) 1.52
The phosphorylation of EphB2 receptor regulates migration and invasion of human glioma cells. Cancer Res (2004) 1.42
EphB2/R-Ras signaling regulates glioma cell adhesion, growth, and invasion. Am J Pathol (2005) 1.41
Ephrin-B3 ligand promotes glioma invasion through activation of Rac1. Cancer Res (2006) 1.38
MAP-ing glioma invasion: mitogen-activated protein kinase kinase 3 and p38 drive glioma invasion and progression and predict patient survival. Mol Cancer Ther (2007) 1.33
Coexpression of ephrin-Bs and their receptors in colon carcinoma. Cancer (2002) 1.29
Glioma cells on the run - the migratory transcriptome of 10 human glioma cell lines. BMC Genomics (2008) 1.28
ephrinB1 signals from the cell surface to the nucleus by recruitment of STAT3. Proc Natl Acad Sci U S A (2007) 1.21
The Eph receptor/ephrin system: an emerging player in the invasion game. Curr Issues Mol Biol (2008) 1.16
Platelet-derived growth factor-mediated gliomagenesis and brain tumor recruitment. Neurosurg Clin N Am (2007) 1.15
High-level expression of EPHB6, EFNB2, and EFNB3 is associated with low tumor stage and high TrkA expression in human neuroblastomas. Clin Cancer Res (1999) 1.13
Therapeutic strategies for inhibiting invasion in glioblastoma. Expert Rev Neurother (2009) 1.13
Overexpression of Lerk-5/Eplg5 messenger RNA: a novel marker for increased tumorigenicity and metastatic potential in human malignant melanomas. Clin Cancer Res (1998) 1.06
Overcoming therapeutic resistance in malignant gliomas: current practices and future directions. Cancer Treat Res (2008) 1.04
EPH receptors in cancer. Histol Histopathol (2008) 1.01
The C-terminus of ephrin-B1 regulates metalloproteinase secretion and invasion of cancer cells. J Cell Sci (2007) 0.95
Overexpression of ephrinB2 and EphB4 in tumor advancement of uterine endometrial cancers. Ann Oncol (2006) 0.95
The significance of EphB4 and EphrinB2 expression and survival in head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg (2008) 0.88
Expression and prognostic significance of EFNB2 and EphB4 genes in patients with oesophageal squamous cell carcinoma. Dig Liver Dis (2007) 0.88
Identification of secreted proteins regulated by cAMP in glioblastoma cells using glycopeptide capture and label-free quantification. Proteomics (2009) 0.85
Similarities and Differences in the Way Transmembrane-Type Ligands Interact with the Elk Subclass of Eph Receptors Mol Cell Neurosci (1996) 0.81
Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment. Clin Cancer Res (2007) 4.99
Retracted Foxp3-positive macrophages display immunosuppressive properties and promote tumor growth. J Exp Med (2011) 3.15
Molecular mechanisms of glioma cell migration and invasion. J Neurooncol (2004) 3.04
Autocrine factors that sustain glioma invasion and paracrine biology in the brain microenvironment. J Natl Cancer Inst (2007) 2.57
Gene expression profile of glioblastoma multiforme invasive phenotype points to new therapeutic targets. Neoplasia (2005) 2.37
Cell migration and invasion assays. Methods (2005) 2.32
Phase I pharmacologic and pharmacodynamic study of the gamma secretase (Notch) inhibitor MK-0752 in adult patients with advanced solid tumors. J Clin Oncol (2012) 2.08
MK-1775, a potent Wee1 inhibitor, synergizes with gemcitabine to achieve tumor regressions, selectively in p53-deficient pancreatic cancer xenografts. Clin Cancer Res (2011) 1.98
A mathematical model of glioblastoma tumor spheroid invasion in a three-dimensional in vitro experiment. Biophys J (2006) 1.91
Increased fibroblast growth factor-inducible 14 expression levels promote glioma cell invasion via Rac1 and nuclear factor-kappaB and correlate with poor patient outcome. Cancer Res (2006) 1.66
Role of synaptojanin 2 in glioma cell migration and invasion. Cancer Res (2004) 1.64
The tyrosine kinase pyk2 promotes migration and invasion of glioma cells. Neoplasia (2005) 1.60
An expression signature classifies chemotherapy-resistant pediatric osteosarcoma. Cancer Res (2005) 1.60
The guanine nucleotide exchange factors trio, Ect2, and Vav3 mediate the invasive behavior of glioblastoma. Am J Pathol (2008) 1.57
Migrating glioma cells activate the PI3-K pathway and display decreased susceptibility to apoptosis. J Cell Sci (2003) 1.52
The human Fn14 receptor gene is up-regulated in migrating glioma cells in vitro and overexpressed in advanced glial tumors. Am J Pathol (2003) 1.47
Lithium inhibits invasion of glioma cells; possible involvement of glycogen synthase kinase-3. Neuro Oncol (2008) 1.47
The phosphorylation of EphB2 receptor regulates migration and invasion of human glioma cells. Cancer Res (2004) 1.42
EphB2/R-Ras signaling regulates glioma cell adhesion, growth, and invasion. Am J Pathol (2005) 1.41
Radiation sensitization of glioblastoma by cilengitide has unanticipated schedule-dependency. Int J Cancer (2009) 1.39
Phase I trial of MK-0752 in children with refractory CNS malignancies: a pediatric brain tumor consortium study. J Clin Oncol (2011) 1.39
Ephrin-B3 ligand promotes glioma invasion through activation of Rac1. Cancer Res (2006) 1.38
Citizen Science Reveals an Extensive Shift in the Winter Distribution of Migratory Western Grebes. PLoS One (2013) 1.34
MAP-ing glioma invasion: mitogen-activated protein kinase kinase 3 and p38 drive glioma invasion and progression and predict patient survival. Mol Cancer Ther (2007) 1.33
Glioma cells on the run - the migratory transcriptome of 10 human glioma cell lines. BMC Genomics (2008) 1.28
RNAi screening of the kinome with cytarabine in leukemias. Blood (2012) 1.25
NHERF-1: modulator of glioblastoma cell migration and invasion. Neoplasia (2009) 1.22
Identification of Fn14/TWEAK receptor as a potential therapeutic target in esophageal adenocarcinoma. Int J Cancer (2007) 1.15
Gamma secretase inhibition promotes hypoxic necrosis in mouse pancreatic ductal adenocarcinoma. J Exp Med (2012) 1.14
Regulation of glioma cell migration by serine-phosphorylated P311. Neoplasia (2005) 1.11
Differential role of proline-rich tyrosine kinase 2 and focal adhesion kinase in determining glioblastoma migration and proliferation. Mol Cancer Res (2003) 1.10
Targeting radiation-induced G(2) checkpoint activation with the Wee-1 inhibitor MK-1775 in glioblastoma cell lines. Mol Cancer Ther (2011) 1.08
The SynCardia freedom driver: a portable driver for discharge home with the total artificial heart. J Heart Lung Transplant (2011) 1.07
TWEAK and Fn14: new molecular targets for cancer therapy? Cancer Lett (2006) 1.06
Implications of Rho GTPase Signaling in Glioma Cell Invasion and Tumor Progression. Front Oncol (2013) 1.05
Molecular pathways triggering glioma cell invasion. Expert Rev Mol Diagn (2006) 1.03
Signals through 4-1BB inhibit T regulatory cells by blocking IL-9 production enhancing antitumor responses. Cancer Immunol Immunother (2011) 1.03
Critical role of the FERM domain in Pyk2 stimulated glioma cell migration. Biochem Biophys Res Commun (2006) 0.98
The Pyk2 FERM domain as a target to inhibit glioma migration. Mol Cancer Ther (2009) 0.98
The small GTPase RhoG mediates glioblastoma cell invasion. Mol Cancer (2012) 0.98
A phase II study of Givinostat in combination with hydroxycarbamide in patients with polycythaemia vera unresponsive to hydroxycarbamide monotherapy. Br J Haematol (2013) 0.97
De novo discovery of a gamma-secretase inhibitor response signature using a novel in vivo breast tumor model. Cancer Res (2009) 0.97
Role of TWEAK and Fn14 in tumor biology. Front Biosci (2007) 0.96
Impact of chemotherapy on normal tissue complication probability models of acute hematologic toxicity in patients receiving pelvic intensity modulated radiation therapy. Int J Radiat Oncol Biol Phys (2013) 0.94
Reciprocal activation of transcription factors underlies the dichotomy between proliferation and invasion of glioma cells. PLoS One (2013) 0.93
Genomic profiling of histological special types of breast cancer. Breast Cancer Res Treat (2013) 0.93
Telomere shortening in the damaged small bile ducts in primary biliary cirrhosis reflects ongoing cellular senescence. Hepatology (2008) 0.93
CpG-ODN but not other TLR-ligands restore the antitumor responses in old mice: the implications for vaccinations in the aged. Cancer Immunol Immunother (2007) 0.92
Statin and Metformin Use Prolongs Survival in Patients With Resectable Pancreatic Cancer. Pancreas (2016) 0.91
Extended survival of Pyk2 or FAK deficient orthotopic glioma xenografts. J Neurooncol (2008) 0.90
GeneRanker: An Online System for Predicting Gene-Disease Associations for Translational Research. Summit on Translat Bioinforma (2008) 0.89
Autotaxin: a secreted autocrine/paracrine factor that promotes glioma invasion. J Neurooncol (2007) 0.89
miRNA expression profiling in migrating glioblastoma cells: regulation of cell migration and invasion by miR-23b via targeting of Pyk2. PLoS One (2012) 0.89
The Prognostic Significance of Pretreatment Hematologic Parameters in Patients Undergoing Resection for Colorectal Cancer. Am J Clin Oncol (2017) 0.88
Specification, annotation, visualization and simulation of a large rule-based model for ERBB receptor signaling. BMC Syst Biol (2012) 0.88
Hypothalamic hamartomas associated with epilepsy: ultrastructural features. J Neuropathol Exp Neurol (2008) 0.87
Comparative kinetic analyses of gene profiles of naïve CD4+ and CD8+ T cells from young and old animals reveal novel age-related alterations. Aging Cell (2011) 0.87
Correlating velocity patterns with spatial dynamics in glioma cell migration. Acta Biotheor (2005) 0.87
Variable wind, pack ice, and prey dispersion affect the long-term adequacy of protected areas for an Arctic sea duck. Ecol Appl (2014) 0.85
Epithelioid glioblastoma changed to typical glioblastoma: the methylation status of MGMT promoter and 5-ALA fluorescence. Brain Tumor Pathol (2010) 0.85
Differential gene expression in auristatin PHE-treated Cryptococcus neoformans. Antimicrob Agents Chemother (2004) 0.85
Combination therapy using Notch and Akt inhibitors is effective for suppressing invasion but not proliferation in glioma cells. Neurosci Lett (2012) 0.85
Regulation of self-renewal in normal and cancer stem cells. FEBS J (2012) 0.84
Regulation of hematopoietic stem cell fate by the ubiquitin proteasome system. Trends Immunol (2012) 0.84
Stable gene selection from microarray data via sample weighting. IEEE/ACM Trans Comput Biol Bioinform (2011) 0.82
Thromboxane synthase inhibitors induce apoptosis in migration-arrested glioma cells. Neurosurgery (2002) 0.80
Ligand-dependent EphB1 signaling suppresses glioma invasion and correlates with patient survival. Neuro Oncol (2013) 0.80
Structural basis and targeting of the interaction between fibroblast growth factor-inducible 14 and tumor necrosis factor-like weak inducer of apoptosis. J Biol Chem (2013) 0.79
Clinical trials in cellular immunotherapy for brain/CNS tumors. Expert Rev Neurother (2013) 0.79
RTK inhibition: looking for the right pathways toward a miracle. Future Oncol (2012) 0.79
Detection of high-risk human papillomavirus subtypes in cervical glandular neoplasia by in situ hybridization. Int J Clin Exp Pathol (2013) 0.78
Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) promotes glioblastoma cell chemotaxis via Lyn activation. Carcinogenesis (2013) 0.78
Strongyloides robustus and the northern sympatric populations of northern (Glaucomys sabrinus) and southern (G. volans) flying squirrels. J Wildl Dis (2004) 0.78
Estimating the cell density and invasive radius of three-dimensional glioblastoma tumor spheroids grown in vitro. Appl Opt (2007) 0.77
Narrow band imaging-guided endoscopic biopsy for intraventricular and paraventricular brain tumors: clinical experience with 14 cases. Acta Neurochir (Wien) (2014) 0.76