Mechanisms and clinical implications of glucocorticosteroids in the treatment of allergic rhinitis.

PubWeight™: 0.89‹?›

🔗 View Article (PMC 2768806)

Published in Clin Exp Immunol on August 06, 2009

Authors

M Okano1

Author Affiliations

1: Department of Otolaryngology - Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan. mokano@cc.okayama-u.ac.jp

Articles cited by this

Control of regulatory T cell development by the transcription factor Foxp3. Science (2003) 40.32

The nuclear receptor superfamily: the second decade. Cell (1995) 24.99

Regulatory T cells and immune tolerance. Cell (2008) 18.77

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen). Allergy (2008) 12.35

A mechanism for the initiation of allergen-induced T helper type 2 responses. Nat Immunol (2008) 6.78

Eosinophils: biological properties and role in health and disease. Clin Exp Allergy (2008) 3.92

Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells. J Exp Med (2004) 3.83

The lifestyle of naturally occurring CD4+ CD25+ Foxp3+ regulatory T cells. Immunol Rev (2006) 3.59

Fluticasone furoate nasal spray: a single treatment option for the symptoms of seasonal allergic rhinitis. J Allergy Clin Immunol (2007) 2.89

IL-10 and TGF-beta cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy. Eur J Immunol (2003) 2.62

Der p 1 facilitates transepithelial allergen delivery by disruption of tight junctions. J Clin Invest (1999) 2.53

Quantitative and functional impairment of pulmonary CD4+CD25hi regulatory T cells in pediatric asthma. J Allergy Clin Immunol (2007) 2.10

Opposing effects of glucocorticoids on the rate of apoptosis in neutrophilic and eosinophilic granulocytes. J Immunol (1996) 2.10

Glucocorticoids upregulate FOXP3 expression and regulatory T cells in asthma. J Allergy Clin Immunol (2004) 1.92

Seasonal allergic rhinitis is associated with a detrimental effect on examination performance in United Kingdom teenagers: case-control study. J Allergy Clin Immunol (2007) 1.84

The glucocorticoid responses are shaped by molecular chaperones. Mol Cell Endocrinol (2007) 1.82

The dominant negative activity of the human glucocorticoid receptor beta isoform. Specificity and mechanisms of action. J Biol Chem (1999) 1.76

Glucocorticoids: effects on gene transcription. Proc Am Thorac Soc (2004) 1.73

Cytokine messenger RNA expression for IL-3, IL-4, IL-5, and granulocyte/macrophage-colony-stimulating factor in the nasal mucosa after local allergen provocation: relationship to tissue eosinophilia. J Immunol (1992) 1.68

Corticosteroid effects on cell signalling. Eur Respir J (2006) 1.63

Chaperoning of glucocorticoid receptors. Handb Exp Pharmacol (2006) 1.62

Nuclear receptors versus inflammation: mechanisms of transrepression. Trends Endocrinol Metab (2006) 1.57

Effect of fluticasone propionate aqueous nasal spray versus oral prednisone on the hypothalamic-pituitary-adrenal axis. J Allergy Clin Immunol (1998) 1.47

Grass pollen immunotherapy induces Foxp3-expressing CD4+ CD25+ cells in the nasal mucosa. J Allergy Clin Immunol (2008) 1.43

Defective suppression of Th2 cytokines by CD4CD25 regulatory T cells in birch allergics during birch pollen season. Clin Exp Allergy (2004) 1.41

CD163: a signal receptor scavenging haptoglobin-hemoglobin complexes from plasma. Int J Biochem Cell Biol (2002) 1.38

Glucocorticoid amplifies IL-2-dependent expansion of functional FoxP3(+)CD4(+)CD25(+) T regulatory cells in vivo and enhances their capacity to suppress EAE. Eur J Immunol (2006) 1.34

Inflammatory mediators in allergic rhinitis. J Allergy Clin Immunol (2004) 1.33

Nasal obstruction as a risk factor for sleep-disordered breathing. The University of Wisconsin Sleep and Respiratory Research Group. J Allergy Clin Immunol (1997) 1.31

HLA-DR- and CD11c-positive dendritic cells penetrate beyond well-developed epithelial tight junctions in human nasal mucosa of allergic rhinitis. J Histochem Cytochem (2005) 1.21

Allergic rhinitis: a disease remodeling the upper airways? J Allergy Clin Immunol (2004) 1.18

Relationship between allergic rhinitis, disturbed cognitive functions and psychological well-being. Clin Exp Allergy (2002) 1.17

TNF-alpha contributes to the development of allergic rhinitis in mice. J Allergy Clin Immunol (2003) 1.09

Molecular and clinical pharmacology of intranasal corticosteroids: clinical and therapeutic implications. Allergy (2008) 1.09

Seasonal allergic rhinitis and antihistamine effects on children's learning. Ann Allergy (1993) 1.08

Absence of growth retardation in children with perennial allergic rhinitis after one year of treatment with mometasone furoate aqueous nasal spray. Pediatrics (2000) 1.08

Expression of epsilon germ-line gene transcripts and mRNA for the epsilon heavy chain of IgE in nasal B cells and the effects of topical corticosteroid. Eur J Immunol (1997) 1.06

Induction of antigen-specific regulatory T lymphocytes by human dendritic cells expressing the glucocorticoid-induced leucine zipper. Blood (2007) 1.01

An essential role for dendritic cells in human and experimental allergic rhinitis. J Allergy Clin Immunol (2006) 1.00

Topical corticosteroid inhibits interleukin-4, -5 and -13 in nasal secretions following allergen challenge. Clin Exp Allergy (2005) 1.00

Effects of pollen and nasal glucocorticoid on FOXP3+, GATA-3+ and T-bet+ cells in allergic rhinitis. Allergy (2007) 0.99

Regulatory T cells in bronchial asthma. Allergy (2009) 0.97

Iatrogenic Cushing's syndrome due to dexamethasone nasal drops. Am J Med (1985) 0.97

No growth suppression in children treated with the maximum recommended dose of fluticasone propionate aqueous nasal spray for one year. Allergy Asthma Proc (2003) 0.97

Acute regulation of tight junction ion selectivity in human airway epithelia. Proc Natl Acad Sci U S A (2009) 0.97

Once daily fluticasone furoate nasal spray is effective in seasonal allergic rhinitis caused by grass pollen. Allergy (2007) 0.96

Foxp3+ T regulatory cells (Tregs) are increased in nasal polyps (NP) after treatment with intranasal steroid. Clin Immunol (2008) 0.96

The presence of both the amino- and carboxyl-terminal domains in the AR is essential for the completion of a transcriptionally active form with coactivators and intranuclear compartmentalization common to the steroid hormone receptors: a three-dimensional imaging study. Mol Endocrinol (2002) 0.92

Phenotypic alteration of neuropeptide-containing nerve fibres in seasonal intermittent allergic rhinitis. Clin Exp Allergy (2004) 0.91

Comparison of fluticasone furoate and fluticasone propionate for the treatment of Japanese cedar pollinosis. Allergy Asthma Proc (2008) 0.91

Differential role of CD80 and CD86 molecules in the induction and the effector phases of allergic rhinitis in mice. Am J Respir Crit Care Med (2001) 0.90

CRTH2 plays an essential role in the pathophysiology of Cry j 1-induced pollinosis in mice. J Immunol (2008) 0.90

Treatment with intranasal fluticasone propionate significantly improves ocular symptoms in patients with seasonal allergic rhinitis. Clin Exp Allergy (2004) 0.90

Dexamethasone inhibits maturation, cytokine production and Fc epsilon RI expression of human cord blood-derived mast cells. Clin Exp Allergy (2002) 0.90

The safety of intranasal steroids. Otolaryngol Head Neck Surg (2003) 0.89

Pathophysiology of allergic rhinitis. Int Arch Allergy Immunol (1996) 0.89

Interleukin-4-independent production of Th2 cytokines by nasal lymphocytes and nasal eosinophilia in murine allergic rhinitis. Allergy (2000) 0.89

How do topical nasal corticosteroids improve sleep and daytime somnolence in allergic rhinitis? J Allergy Clin Immunol (2005) 0.88

Vascular endothelial growth factor in allergen-induced nasal inflammation. Clin Exp Allergy (2009) 0.88

Effect of intranasal fluticasone on cellular infiltration, endothelial adhesion molecule expression, and proinflammatory cytokine mRNA in nasal polyp disease. J Allergy Clin Immunol (1999) 0.88

Lesson of the week: Depot corticosteroid treatment for hay fever causing avascular necrosis of both hips. BMJ (2001) 0.87

Nasal ocular reflexes and eye symptoms in patients with allergic rhinitis. Ann Allergy Asthma Immunol (2008) 0.87

Recruitment of CD1a+ Langerhans cells to the nasal mucosa in seasonal allergic rhinitis and effects of topical corticosteroid therapy. Allergy (2001) 0.87

Glucocorticosteroids inhibit leukotriene production. Ann Allergy Asthma Immunol (1997) 0.86

Induction of nasal hyper-responsiveness by allergen challenge in allergic rhinitis: the role of afferent and efferent nerves. Clin Exp Allergy (2005) 0.85

Double-stranded RNA induces production of RANTES and IL-8 by human nasal fibroblasts. Clin Immunol (2005) 0.85

Bioavailability of fluticasone propionate and mometasone furoate aqueous nasal sprays. Eur J Clin Pharmacol (2004) 0.85

Topical budesonide treatment reduces endothelial expression of intercellular adhesion molecules (vascular cell adhesion molecule-1 and P-selectin) and eosinophil infiltration in nasal polyps. Acta Otolaryngol (1999) 0.85

Microbial superantigens induce glucocorticoid receptor beta and steroid resistance in a nasal explant model. Laryngoscope (2004) 0.83

Systemic corticosteroid treatment for seasonal allergic rhinitis: a common but poorly documented therapy. Allergy (2000) 0.83

A placebo- and active-controlled randomized trial of prophylactic treatment of seasonal allergic rhinitis with mometasone furoate aqueous nasal spray. J Allergy Clin Immunol (1996) 0.82

Influence of fluticasone propionate on the production of vascular endothelial growth factor and basic fibroblast growth factor from nasal fibroblasts in vitro. In Vivo (2005) 0.81

Suppression of matrix metalloproteinase production from nasal fibroblasts by fluticasone propionate in vitro. Acta Otolaryngol (2004) 0.81

Involvement of cysteinyl leukotrienes in biphasic increase of nasal airway resistance of antigen-induced rhinitis in guinea pigs. Eur J Pharmacol (1999) 0.81

Substance P as a potent stimulator of sneeze responses in experimental allergic rhinitis of guinea pigs. Agents Actions (1992) 0.80

Physiologic responses and histamine release after nasal antigen challenge. Effect of atropine. Am J Respir Crit Care Med (1994) 0.80

Fluticasone propionate downregulates nasal fibroblast functions involved in airway inflammation and remodeling. Int Arch Allergy Immunol (2002) 0.78

CT assessment of the effect of fluticasone propionate aqueous nasal spray treatment on lower turbinate hypertrophy due to vasomotor rhinitis. Acta Otolaryngol (2006) 0.78

Signals through CD40 play a critical role in the pathophysiology of Schistosoma mansoni egg antigen--induced allergic rhinitis in mice. Am J Rhinol (2006) 0.78

Eosinophil cationic protein and specific IgE in serum and nasal mucosa of patients with grass-pollen-allergic rhinitis and asthma. Allergy (2001) 0.78

Intranasal mometasone furoate reduces late-phase inflammation after allergen challenge. Ann Allergy Asthma Immunol (2001) 0.78

Important roles of tachykinins in the development of allergic nasal hyperresponsiveness in guinea-pigs. Clin Exp Allergy (2008) 0.78

Nerve growth factor localization in the nasal mucosa of patients with persistent allergic rhinitis. Allergy (2008) 0.78

Expression of costimulatory CD80/CD86-CD28/CD152 molecules in nasal mucosa of patients with perennial allergic rhinitis. Clin Exp Allergy (2001) 0.78

Inhibition of GM-CSF secretion by topical corticosteroids and nedocromil sodium. A comparison study using nasal polyp epithelial cells. Respir Med (2000) 0.78

The role of chemical mediators and mucosal hyperreactivity in nasal hypersecretion in nasal allergy. J Allergy Clin Immunol (1987) 0.77

An in vitro comparison of commonly used topical glucocorticoid preparations. J Allergy Clin Immunol (1999) 0.77

Nasal nitric oxide and nasal allergy. Allergy (2006) 0.77

Expression of adhesion molecules in cultured human nasal mucosal microvascular endothelial cells activated by interleukin-1 beta or tumor necrosis factor-alpha: effects of dexamethasone. Int Arch Allergy Immunol (1998) 0.76

Oral methylprednisolone acetate (Medrol Tablets) for seasonal rhinitis: examination of dose and symptom response. J Clin Pharmacol (1993) 0.76

Different mechanisms between thromboxane A2- and leukotriene D4-induced nasal blockage in guinea pigs. Prostaglandins Other Lipid Mediat (2006) 0.76

Glucocorticoids may not inhibit plasma exudation by direct vascular antipermeability effects in human airways. Eur Respir J (1994) 0.76

Nasal nitric oxide does not control basal nasal patency or acute congestion following allergen challenge in allergic rhinitis. Ann Otol Rhinol Laryngol (1999) 0.76

Daytime sleepiness and cognitive performance improve in seasonal allergic rhinitis treated with intranasal fluticasone propionate. Allergy Asthma Proc (2007) 0.75