Published in BMC Genomics on September 08, 2009
GeneFriends: an online co-expression analysis tool to identify novel gene targets for aging and complex diseases. BMC Genomics (2012) 1.10
Brain-derived neurotrophic factor expression predicts adverse pathological & clinical outcomes in human breast cancer. Cancer Cell Int (2011) 1.02
Genome-wide expression patterns in physiological cardiac hypertrophy. BMC Genomics (2010) 0.89
Expression analysis of prestin and selected transcription factors in newborn rats. Cell Mol Neurobiol (2011) 0.85
BDNF is associated with SFRP1 expression in luminal and basal-like breast cancer cell lines and primary breast cancer tissues: a novel role in tumor suppression? PLoS One (2014) 0.80
Mining kidney toxicogenomic data by using gene co-expression modules. BMC Genomics (2016) 0.75
The human genome browser at UCSC. Genome Res (2002) 168.23
Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A (2001) 132.88
Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res (2002) 76.95
A gene-coexpression network for global discovery of conserved genetic modules. Science (2003) 18.75
A general framework for weighted gene co-expression network analysis. Stat Appl Genet Mol Biol (2005) 17.23
TRANSFAC: an integrated system for gene expression regulation. Nucleic Acids Res (2000) 15.70
Coexpression analysis of human genes across many microarray data sets. Genome Res (2004) 9.38
DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation. Science (2003) 8.81
g:Profiler--a web-based toolset for functional profiling of gene lists from large-scale experiments. Nucleic Acids Res (2007) 6.44
A gene network for navigating the literature. Nat Genet (2004) 6.43
Ca2+ influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism. Neuron (1998) 5.05
ECR Browser: a tool for visualizing and accessing data from comparisons of multiple vertebrate genomes. Nucleic Acids Res (2004) 4.53
Sequence-matched probes produce increased cross-platform consistency and more reproducible biological results in microarray-based gene expression measurements. Nucleic Acids Res (2004) 4.43
Mouse and rat BDNF gene structure and expression revisited. J Neurosci Res (2007) 4.13
Insights into host responses against pathogens from transcriptional profiling. Nat Rev Microbiol (2005) 4.11
Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system. Genes Dev (2000) 4.07
From synapse to nucleus: calcium-dependent gene transcription in the control of synapse development and function. Neuron (2008) 4.02
New insights into BDNF function in depression and anxiety. Nat Neurosci (2007) 3.94
A requirement for the immediate early gene Zif268 in the expression of late LTP and long-term memories. Nat Neurosci (2001) 3.56
Differential coexpression analysis using microarray data and its application to human cancer. Bioinformatics (2005) 3.17
Approaches for extracting practical information from gene co-expression networks in plant biology. Plant Cell Physiol (2007) 3.13
Dissecting the human BDNF locus: bidirectional transcription, complex splicing, and multiple promoters. Genomics (2007) 2.89
Systematic survey reveals general applicability of "guilt-by-association" within gene coexpression networks. BMC Bioinformatics (2005) 2.83
Identification of a signaling pathway involved in calcium regulation of BDNF expression. Neuron (1998) 2.82
A tumor suppressor and oncogene: the WT1 story. Leukemia (2007) 2.81
DNA-binding specificity of NGFI-A and related zinc finger transcription factors. Mol Cell Biol (1995) 2.78
Predicting tissue-specific enhancers in the human genome. Genome Res (2007) 2.72
A calcium-responsive transcription factor, CaRF, that regulates neuronal activity-dependent expression of BDNF. Neuron (2002) 2.65
Coexpression of neighboring genes in the genome of Arabidopsis thaliana. Genome Res (2004) 2.52
Network neighborhood analysis with the multi-node topological overlap measure. Bioinformatics (2006) 2.35
Rodent BDNF genes, novel promoters, novel splice variants, and regulation by cocaine. Brain Res (2005) 2.34
Assessment and integration of publicly available SAGE, cDNA microarray, and oligonucleotide microarray expression data for global coexpression analyses. Genomics (2005) 2.27
EGR2 mutations in inherited neuropathies dominant-negatively inhibit myelin gene expression. Neuron (2001) 2.08
Gfi1 coordinates epigenetic repression of p21Cip/WAF1 by recruitment of histone lysine methyltransferase G9a and histone deacetylase 1. Mol Cell Biol (2005) 2.07
Proneural bHLH and Brn proteins coregulate a neurogenic program through cooperative binding to a conserved DNA motif. Dev Cell (2006) 2.06
TiProD: the Tissue-specific Promoter Database. Nucleic Acids Res (2006) 1.89
Transcription factor MEF2C influences neural stem/progenitor cell differentiation and maturation in vivo. Proc Natl Acad Sci U S A (2008) 1.87
Calpain-regulated p35/cdk5 plays a central role in dopaminergic neuron death through modulation of the transcription factor myocyte enhancer factor 2. J Neurosci (2006) 1.61
Human brain derived neurotrophic factor (BDNF) genes, splicing patterns, and assessments of associations with substance abuse and Parkinson's Disease. Am J Med Genet B Neuropsychiatr Genet (2005) 1.60
Coronary vessel development requires activation of the TrkB neurotrophin receptor by the Wilms' tumor transcription factor Wt1. Genes Dev (2005) 1.60
Increased expression of the insulin-like growth factor I receptor gene, IGF1R, in Wilms tumor is correlated with modulation of IGF1R promoter activity by the WT1 Wilms tumor gene product. Proc Natl Acad Sci U S A (1993) 1.59
BDNF and memory formation and storage. Neuroscientist (2007) 1.56
Control of myelination in Schwann cells: a Krox20 cis-regulatory element integrates Oct6, Brn2 and Sox10 activities. EMBO Rep (2006) 1.56
Egr transcription factors in the nervous system. Neurochem Int (1997) 1.56
Neurotrophic mechanisms in drug addiction. Neuromolecular Med (2004) 1.54
Systematic construction of gene coexpression networks with applications to human T helper cell differentiation process. Bioinformatics (2007) 1.54
Reduced BDNF mRNA expression in the Parkinson's disease substantia nigra. Exp Neurol (2000) 1.45
CONFAC: automated application of comparative genomic promoter analysis to DNA microarray datasets. Nucleic Acids Res (2004) 1.44
Egr3, a synaptic activity regulated transcription factor that is essential for learning and memory. Mol Cell Neurosci (2007) 1.44
DiRE: identifying distant regulatory elements of co-expressed genes. Nucleic Acids Res (2008) 1.42
Involvement of an upstream stimulatory factor as well as cAMP-responsive element-binding protein in the activation of brain-derived neurotrophic factor gene promoter I. J Biol Chem (2002) 1.41
From co-expression to co-regulation: how many microarray experiments do we need? Genome Biol (2004) 1.40
Upstream stimulatory factors are mediators of Ca2+-responsive transcription in neurons. J Neurosci (2003) 1.33
Sequence-specific recruitment of transcriptional co-repressor Cabin1 by myocyte enhancer factor-2. Nature (2003) 1.32
Specificity and timing of neocortical transcriptome changes in response to BDNF gene ablation during embryogenesis or adulthood. Mol Psychiatry (2006) 1.30
Differential usage of multiple brain-derived neurotrophic factor promoters in the rat brain following neuronal activation. Proc Natl Acad Sci U S A (1993) 1.23
Expression of the neurotrophin receptor TrkB is associated with unfavorable outcome in Wilms' tumor. J Clin Oncol (2001) 1.20
Gene regulation by hypoxia and the neurodevelopmental origin of schizophrenia. Schizophr Res (2006) 1.19
The EWS-WT1 translocation product induces PDGFA in desmoplastic small round-cell tumour. Nat Genet (1997) 1.17
Brain-derived neurotrophic factor expression in vivo is under the control of neuron-restrictive silencer element. J Biol Chem (1999) 1.17
Parkinson's disease: a genetic perspective. FEBS J (2008) 1.16
Conserved co-expression for candidate disease gene prioritization. BMC Bioinformatics (2008) 1.15
BDNF and the diseased nervous system: a delicate balance between adaptive and pathological processes of gene regulation. J Neurochem (2008) 1.10
Effects of brain-derived neurotrophic factor (BDNF) on glial cells and serotonergic neurones during development. J Neurochem (2005) 1.09
Senseless physically interacts with proneural proteins and functions as a transcriptional co-activator. Development (2006) 1.08
Multiple genes and factors associated with bipolar disorder converge on growth factor and stress activated kinase pathways controlling translation initiation: implications for oligodendrocyte viability. Neurochem Int (2007) 1.07
Nuclear factor kappaB is a critical determinant in N-methyl-D-aspartate receptor-mediated neuroprotection. J Neurochem (2001) 1.04
The expression signature of in vitro senescence resembles mouse but not human aging. Genome Biol (2005) 1.03
Quantitative proteomic identification of MAZ as a transcriptional regulator of muscle-specific genes in skeletal and cardiac myocytes. Mol Cell Biol (2008) 1.01
Transcriptional regulation of activating transcription factor 3 involves the early growth response-1 gene. J Pharmacol Exp Ther (2005) 1.01
Two closely related ubiquitin C-terminal hydrolase isozymes function as reciprocal modulators of germ cell apoptosis in cryptorchid testis. Am J Pathol (2004) 0.99
The growth factor independence-1 transcription factor: new functions and new insights. Crit Rev Oncol Hematol (2006) 0.97
Fibroblast growth factor 2 applied to the optic nerve after axotomy up-regulates BDNF and TrkB in ganglion cells by activating the ERK and PKA signaling pathways. J Neurochem (2005) 0.95
Molecular cloning of rat Wilms' tumor complementary DNA and a study of messenger RNA expression in the urogenital system and the brain. Cancer Res (1992) 0.94
Inactivation of glycogen synthase kinase-3beta contributes to brain-derived neutrophic factor/TrkB-induced resistance to chemotherapy in neuroblastoma cells. Mol Cancer Ther (2007) 0.94
LAR protein tyrosine phosphatase receptor associates with TrkB and modulates neurotrophic signaling pathways. J Neurobiol (2006) 0.93
Calcium/calmodulin inhibition of transcriptional activity of E-proteins by prevention of their binding to DNA. J Biol Chem (2004) 0.93
Identification of brain-derived neurotrophic factor as a novel functional protein in hepatocellular carcinoma. Cancer Res (2005) 0.92
Haploinsufficiency for trkB and trkC receptors induces cell loss and accumulation of alpha-synuclein in the substantia nigra. FASEB J (2005) 0.91
MAZ drives tumor-specific expression of PPAR gamma 1 in breast cancer cells. Breast Cancer Res Treat (2007) 0.90
Identification of brain-derived neurotrophic factor as a novel angiogenic protein in multiple myeloma. Cancer Genet Cytogenet (2007) 0.88
Secreted proteins and genes in fetal and neonatal pig adipose tissue and stromal-vascular cells. J Anim Sci (2006) 0.88
Transcriptional regulation by zinc-finger proteins Sp1 and MAZ involves interactions with the same cis-elements. Int J Mol Med (2003) 0.88
Myocyte enhancer factor 2C upregulates MASH-1 expression and induces neurogenesis in P19 cells. FEBS Lett (2000) 0.85
Puralpha activates PDGF-A gene transcription via interactions with a G-rich, single-stranded region of the promoter. Gene (2005) 0.85
Proteolytic processing of chromogranin B and secretogranin II by prohormone convertases. J Neurochem (1998) 0.85
Transcriptional profiling of brain-derived-neurotrophic factor-induced neuronal plasticity: a novel role for nociceptin in hippocampal neurite outgrowth. J Neurobiol (2006) 0.85
Brain-derived neurotrophic factor inducing angiogenesis through modulation of matrix-degrading proteases. Chin Med J (Engl) (2006) 0.85
The pro-protein convertase PC1 is induced in the transected sciatic nerve and is present in cultured Schwann cells: comparison with PC5, furin and PC7, implication in pro-BDNF processing. Brain Res Mol Brain Res (1998) 0.84
Neurotrophin system expression in human pulmonary carcinoid tumors. Growth Factors (2005) 0.84
Wilms' tumor suppressor (WT1) is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer's disease. Brain Res (2003) 0.83
BDNF is induced by wild-type alpha-synuclein but not by the two mutants, A30P or A53T, in glioma cell line. Biochem Biophys Res Commun (2004) 0.83
Expression of WT1 protein and correlation with cellular proliferation in glial tumors. Neurol Med Chir (Tokyo) (2007) 0.82
Coactivation of secretogranin-II and BDNF genes mediated by calcium signals in mouse cerebellar granule cells. Brain Res Mol Brain Res (1999) 0.81
Unliganded c-erbA/thyroid hormone receptor induces trkB expression in neuroblastoma cells. Oncogene (1994) 0.81
Behavioral testing upregulates pCaMKII, BDNF, PSD-95 and egr-1 in hippocampus of FVB/N mice. Behav Brain Res (2005) 0.80
The modulator is a constitutive enhancer of a developmentally regulated sea urchin histone H2A gene. Bioessays (2002) 0.78
Candidate Sertoli cell specific promoter element for a TGFbeta family member (Amh) and a 3' UTR enhancer/repressor for the same gene. Gene (2005) 0.78
Lecithinized brain-derived neurotrophic factor promotes the differentiation of embryonic stem cells in vitro and in vivo. Biochem Biophys Res Commun (2005) 0.77
Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes. Nat Genet (2003) 4.76
Mouse and rat BDNF gene structure and expression revisited. J Neurosci Res (2007) 4.13
Dissecting the human BDNF locus: bidirectional transcription, complex splicing, and multiple promoters. Genomics (2007) 2.89
A general species delimitation method with applications to phylogenetic placements. Bioinformatics (2013) 2.60
A novel gene family encoding leucine-rich repeat transmembrane proteins differentially expressed in the nervous system. Genomics (2003) 1.67
Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo. Nature (2007) 1.62
Identification of cis-elements and transcription factors regulating neuronal activity-dependent transcription of human BDNF gene. J Neurosci (2011) 1.40
MANF is widely expressed in mammalian tissues and differently regulated after ischemic and epileptic insults in rodent brain. Mol Cell Neurosci (2008) 1.29
Two novel mammalian Nogo receptor homologs differentially expressed in the central and peripheral nervous systems. Mol Cell Neurosci (2003) 1.21
1000 Genomes Selection Browser 1.0: a genome browser dedicated to signatures of natural selection in modern humans. Nucleic Acids Res (2013) 1.20
Evolution of self-compatibility in Arabidopsis by a mutation in the male specificity gene. Nature (2010) 1.18
Structure, alternative splicing, and expression of the human and mouse KCNIP gene family. Genomics (2005) 1.14
Alternative splicing and expression of human and mouse NFAT genes. Genomics (2008) 1.12
Functional diversity of human basic helix-loop-helix transcription factor TCF4 isoforms generated by alternative 5' exon usage and splicing. PLoS One (2011) 1.12
Nuclear factor of activated T-cells isoform c4 (NFATc4/NFAT3) as a mediator of antiapoptotic transcription in NMDA receptor-stimulated cortical neurons. J Neurosci (2009) 1.11
Pitt-Hopkins syndrome-associated mutations in TCF4 lead to variable impairment of the transcription factor function ranging from hypomorphic to dominant-negative effects. Hum Mol Genet (2012) 1.06
Long-lasting behavioural and molecular alterations induced by early postnatal fluoxetine exposure are restored by chronic fluoxetine treatment in adult mice. Eur Neuropsychopharmacol (2008) 1.03
Human TrkB gene: novel alternative transcripts, protein isoforms and expression pattern in the prefrontal cerebral cortex during postnatal development. J Neurochem (2010) 1.01
Selection on cis-regulatory variation at B4galnt2 and its influence on von Willebrand factor in house mice. Mol Biol Evol (2008) 1.01
NF-kappaB-dependent regulation of brain-derived neurotrophic factor in hippocampal neurons by X-linked inhibitor of apoptosis protein. Eur J Neurosci (2009) 1.00
Primate genome architecture influences structural variation mechanisms and functional consequences. Proc Natl Acad Sci U S A (2013) 0.97
Regulation of extracellular serotonin levels and brain-derived neurotrophic factor in rats with high and low exploratory activity. Brain Res (2007) 0.91
N-terminally truncated BAF57 isoforms contribute to the diversity of SWI/SNF complexes in neurons. J Neurochem (2009) 0.87
The turbulent life of Sirevirus retrotransposons and the evolution of the maize genome: more than ten thousand elements tell the story. Plant J (2011) 0.87
Recent strong positive selection on Drosophila melanogaster HDAC6, a gene encoding a stress surveillance factor, as revealed by population genomic analysis. Mol Biol Evol (2009) 0.87
Selective sweep of a cis-regulatory sequence in a non-African population of Drosophila melanogaster. Mol Biol Evol (2011) 0.86
Tissue-specific and neural activity-regulated expression of human BDNF gene in BAC transgenic mice. BMC Neurosci (2009) 0.84
Identification of X-linked quantitative trait loci affecting cold tolerance in Drosophila melanogaster and fine mapping by selective sweep analysis. Mol Ecol (2010) 0.84
Inference of seed bank parameters in two wild tomato species using ecological and genetic data. Proc Natl Acad Sci U S A (2011) 0.83
Expression of NGF and GDNF family members and their receptors during peripheral nerve development and differentiation of Schwann cells in vitro. Neurosci Lett (2009) 0.82
Expression analysis of the CLCA gene family in mouse and human with emphasis on the nervous system. BMC Dev Biol (2009) 0.81
Neuronal K+/Cl- co-transporter (KCC2) transgenes lacking neurone restrictive silencer element recapitulate CNS neurone-specific expression and developmental up-regulation of endogenous KCC2 gene. J Neurochem (2005) 0.80
BAC transgenic mice reveal distal cis-regulatory elements governing BDNF gene expression. Genesis (2010) 0.80
Selective sweep in the Flotillin-2 region of European Drosophila melanogaster. PLoS One (2013) 0.78
Subcellular localization and transcription regulatory potency of KCNIP/Calsenilin/DREAM/KChIP proteins in cultured primary cortical neurons do not provide support for their role in CRE-dependent gene expression. J Neurochem (2012) 0.78
Bidirectional transcription from human LRRTM2/CTNNA1 and LRRTM1/CTNNA2 gene loci leads to expression of N-terminally truncated CTNNA1 and CTNNA2 isoforms. Biochem Biophys Res Commun (2011) 0.78
Sudden death after myocardial infarction in a high-school athlete. J Forensic Sci (2010) 0.78
Geographic distribution and adaptive significance of genomic structural variants: an anthropological genetics perspective. Hum Biol (2014) 0.77
Potential efficacy of early treatment of acute acoustic trauma with steroids and piracetam after gunshot noise. Eur Arch Otorhinolaryngol (2008) 0.76
Effects of walking on heart rate recovery, endothelium modulators and quality of life in patients with heart failure. Eur J Cardiovasc Prev Rehabil (2011) 0.76
BAC-based cellular model for screening regulators of BDNF gene transcription. BMC Neurosci (2014) 0.75
Head trauma by captive bolt gun. BMJ Case Rep (2011) 0.75
Concurrent lumbosacral and sacrococcygeal fusion; a rare etiology of low back pain and coccygodynia? Folia Morphol (Warsz) (2017) 0.75
Infantile Respiratory Distress Syndrome and Its Probable Links With Parameters of the Maternal Patient History: A Forensic Case Report. Am J Forensic Med Pathol (2016) 0.75
Reversible dilated cardiomyopathy due to subclinical hyperthyroidism. Hellenic J Cardiol (2010) 0.75
Myocardial hypertrophy induces carotid body hyperplasia. J Forensic Sci (2010) 0.75
Complex suicide involving pyrethroid ingestion (mosquito coils) and fatal self-wounding by sharp force. Soud Lek (2017) 0.75
Neuralized-2: expression in human and rodents and interaction with Delta-like ligands. Biochem Biophys Res Commun (2009) 0.75
A validated UHPLC-diode array detector method for the bioanalysis of atypical antipsychotics in whole blood, urine and cerebrospinal fluid following SPE. Bioanalysis (2012) 0.75
Concurrent lumbosacral and sacrococcygeal fusion; a rare etiology of low back pain and coccygodynia? Folia Morphol (Warsz) (2017) 0.75
Can Severe Kyphoscoliosis Lead to Aorta Rupture? Am J Forensic Med Pathol (2016) 0.75