Published in Ann Neurol on August 01, 2009
T cells in multiple sclerosis and experimental autoimmune encephalomyelitis. Clin Exp Immunol (2010) 2.94
Long non-coding RNAs in nervous system function and disease. Brain Res (2010) 2.53
Overrepresentation of IL-17A and IL-22 producing CD8 T cells in lesional skin suggests their involvement in the pathogenesis of psoriasis. PLoS One (2010) 1.73
Fingolimod modulates peripheral effector and regulatory T cells in MS patients. J Neuroimmune Pharmacol (2013) 1.59
Modeling the heterogeneity of multiple sclerosis in animals. Trends Immunol (2013) 1.25
Using EAE to better understand principles of immune function and autoimmune pathology. J Autoimmun (2013) 1.20
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Glial influence on the blood brain barrier. Glia (2013) 1.12
Teriflunomide and its mechanism of action in multiple sclerosis. Drugs (2014) 1.08
The immunomodulatory and neuroprotective effects of mesenchymal stem cells (MSCs) in experimental autoimmune encephalomyelitis (EAE): a model of multiple sclerosis (MS). Int J Mol Sci (2012) 1.02
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CD8+ T cells cause disability and axon loss in a mouse model of multiple sclerosis. PLoS One (2010) 0.99
Unbiased identification of target antigens of CD8+ T cells with combinatorial libraries coding for short peptides. Nat Med (2012) 0.97
B cell-derived IL-15 enhances CD8 T cell cytotoxicity and is increased in multiple sclerosis patients. J Immunol (2011) 0.94
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Proteasome immunosubunits protect against the development of CD8 T cell-mediated autoimmune diseases. J Immunol (2011) 0.93
The proteoglycan biglycan enhances antigen-specific T cell activation potentially via MyD88 and TRIF pathways and triggers autoimmune perimyocarditis. J Immunol (2011) 0.92
Heterogeneity in multiple sclerosis: scratching the surface of a complex disease. Autoimmune Dis (2010) 0.92
The influence of T cell Ig mucin-3 signaling on central nervous system autoimmune disease is determined by the effector function of the pathogenic T cells. J Immunol (2013) 0.91
αβ T-cell receptors from multiple sclerosis brain lesions show MAIT cell-related features. Neurol Neuroimmunol Neuroinflamm (2015) 0.88
Role of regulatory T cells in pathogenesis and biological therapy of multiple sclerosis. Mediators Inflamm (2013) 0.86
Development of oral cladribine for the treatment of multiple sclerosis. J Neurol (2010) 0.86
CD8+ regulatory T cells induced by T cell vaccination protect against autoimmune nephritis. J Am Soc Nephrol (2012) 0.86
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The effect of omeprazole on the development of experimental autoimmune encephalomyelitis in C57BL/6J and SJL/J mice. BMC Res Notes (2014) 0.85
CD8 and CD4 T cells in west nile virus immunity and pathogenesis. Viruses (2013) 0.83
What do effective treatments for multiple sclerosis tell us about the molecular mechanisms involved in pathogenesis? Int J Mol Sci (2012) 0.81
Ectopic T-cell specificity and absence of perforin and granzyme B alleviate neural damage in oligodendrocyte mutant mice. Am J Pathol (2009) 0.80
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The retrovirus/superantigen hypothesis of multiple sclerosis. Cell Mol Neurobiol (2014) 0.77
Flow cytometric assay detecting cytotoxicity against human endogenous retrovirus antigens expressed on cultured multiple sclerosis cells. Clin Exp Immunol (2013) 0.77
The Non-Obese Diabetic Mouse Strain as a Model to Study CD8(+) T Cell Function in Relapsing and Progressive Multiple Sclerosis. Front Immunol (2015) 0.77
Wnt signaling inhibits CTL memory programming. Mol Immunol (2013) 0.77
Spontaneous ocular and neurologic deficits in transgenic mouse models of multiple sclerosis and noninvasive investigative modalities: a review. Invest Ophthalmol Vis Sci (2012) 0.77
Identification of human viral protein-derived ligands recognized by individual MHCI-restricted T-cell receptors. Immunol Cell Biol (2016) 0.76
Impaired toll-like receptor 8 signaling in multiple sclerosis. J Neuroinflammation (2013) 0.76
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Targeted suppression of autoreactive CD8(+) T-cell activation using blocking anti-CD8 antibodies. Sci Rep (2016) 0.75
Evaluation of the circulating CD34(+), CD309(+), and endothelial progenitor cells in patients with first attack of optic neuritis. Adv Biomed Res (2015) 0.75
Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis. Am J Pathol (2007) 5.27
MHC class II proteins and disease: a structural perspective. Nat Rev Immunol (2006) 2.66
Tandem-pore K+ channels mediate inhibition of orexin neurons by glucose. Neuron (2006) 2.53
A functional and structural basis for TCR cross-reactivity in multiple sclerosis. Nat Immunol (2002) 2.31
Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system. Nat Med (2007) 2.28
Constitutively active Lck kinase in T cells drives antigen receptor signal transduction. Immunity (2010) 2.22
Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis. Nat Med (2008) 2.19
Conflicting selective forces affect T cell receptor contacts in an immunodominant human immunodeficiency virus epitope. Nat Immunol (2006) 2.11
Control of hypothalamic orexin neurons by acid and CO2. Proc Natl Acad Sci U S A (2007) 1.99
Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance. Nat Immunol (2009) 1.83
Autoreactive CD8+ T cells in multiple sclerosis: a new target for therapy? Brain (2005) 1.79
Functional epistasis on a common MHC haplotype associated with multiple sclerosis. Nature (2006) 1.75
The nature of molecular recognition by T cells. Nat Immunol (2003) 1.70
Destructive processing by asparagine endopeptidase limits presentation of a dominant T cell epitope in MBP. Nat Immunol (2002) 1.61
Predominant selection of T cells specific for the glycosylated collagen type II epitope (263-270) in humanized transgenic mice and in rheumatoid arthritis. Proc Natl Acad Sci U S A (2002) 1.55
Inherited deficiency of mannan-binding lectin-associated serine protease 2. N Engl J Med (2003) 1.52
T cell-mediated autoimmune disease due to low-affinity crossreactivity to common microbial peptides. Immunity (2009) 1.50
Crystal structure of HLA-DQ0602 that protects against type 1 diabetes and confers strong susceptibility to narcolepsy. Proc Natl Acad Sci U S A (2004) 1.29
Metabolism-independent sugar sensing in central orexin neurons. Diabetes (2008) 1.21
Adaptive sugar sensors in hypothalamic feeding circuits. Proc Natl Acad Sci U S A (2008) 1.18
Activation of central orexin/hypocretin neurons by dietary amino acids. Neuron (2011) 1.18
Autoimmunity's next top models. Nat Med (2012) 1.14
IL-21 and IL-21 receptor expression in lymphocytes and neurons in multiple sclerosis brain. Am J Pathol (2011) 1.11
The value of animal models for drug development in multiple sclerosis. Brain (2006) 1.11
Acid-sensing ion channel 1 is involved in both axonal injury and demyelination in multiple sclerosis and its animal model. Brain (2011) 1.05
Therapies for multiple sclerosis: translational achievements and outstanding needs. Trends Mol Med (2013) 1.04
Use of calcium channel blockers and Parkinson's disease. Am J Epidemiol (2012) 1.03
Myelin oligodendrocyte glycoprotein-35-55 peptide induces severe chronic experimental autoimmune encephalomyelitis in HLA-DR2-transgenic mice. Eur J Immunol (2004) 0.99
Deletion of TASK1 and TASK3 channels disrupts intrinsic excitability but does not abolish glucose or pH responses of orexin/hypocretin neurons. Eur J Neurosci (2009) 0.98
Tolerance to ingested deamidated gliadin in mice is maintained by splenic, type 1 regulatory T cells. Gastroenterology (2011) 0.96
The immunodominant myeloperoxidase T-cell epitope induces local cell-mediated injury in antimyeloperoxidase glomerulonephritis. Proc Natl Acad Sci U S A (2012) 0.96
MHC II molecules in inflammatory diseases: interplay of qualities and quantities. Trends Immunol (2005) 0.95
Therapeutic vaccination of active arthritis with a glycosylated collagen type II peptide in complex with MHC class II molecules. J Immunol (2006) 0.95
APOBEC3G-induced hypermutation of human immunodeficiency virus type-1 is typically a discrete "all or nothing" phenomenon. PLoS Genet (2012) 0.95
Novel synthetic amino acid copolymers that inhibit autoantigen-specific T cell responses and suppress experimental autoimmune encephalomyelitis. J Clin Invest (2002) 0.95
In vivo enhancement of peptide display by MHC class II molecules with small molecule catalysts of peptide exchange. J Immunol (2009) 0.93
Humanized mouse models for organ-specific autoimmune diseases. Curr Opin Immunol (2006) 0.93
Tracking of proinflammatory collagen-specific T cells in early and late collagen-induced arthritis in humanized mice. J Immunol (2004) 0.91
Structure of HLA-A*0301 in complex with a peptide of proteolipid protein: insights into the role of HLA-A alleles in susceptibility to multiple sclerosis. Acta Crystallogr D Biol Crystallogr (2011) 0.90
Targeting ASIC1 in primary progressive multiple sclerosis: evidence of neuroprotection with amiloride. Brain (2013) 0.90
The HLA-DRB1*15:01-restricted Goodpasture's T cell epitope induces GN. J Am Soc Nephrol (2013) 0.89
Orexin neurons as conditional glucosensors: paradoxical regulation of sugar sensing by intracellular fuels. J Physiol (2011) 0.89
Convergent inputs from electrically and topographically distinct orexin cells to locus coeruleus and ventral tegmental area. Eur J Neurosci (2012) 0.88
Human X-linked variable immunodeficiency caused by a hypomorphic mutation in XIAP in association with a rare polymorphism in CD40LG. Blood (2011) 0.87
Natural killer cells and their receptors in multiple sclerosis. Brain (2012) 0.87
Redirecting therapeutic T cells against myelin-specific T lymphocytes using a humanized myelin basic protein-HLA-DR2-zeta chimeric receptor. J Immunol (2008) 0.86
Direct and indirect control of orexin/hypocretin neurons by glycine receptors. J Physiol (2010) 0.84
T cells and microglia as drivers of multiple sclerosis pathology. Brain (2007) 0.83
Efficient presentation of myelin oligodendrocyte glycoprotein peptides but not protein by astrocytes from HLA-DR2 and HLA-DR4 transgenic mice. J Neuroimmunol (2006) 0.81
Efficient purification of unique antibodies using peptide affinity-matrix columns. J Immunol Methods (2004) 0.81
Longitudinal and cross-sectional studies of HIV-1 RNA and DNA loads in blood and the female genital tract. Eur J Obstet Gynecol Reprod Biol (2004) 0.80
Bridging the gap from genetic association to functional understanding: the next generation of mouse models of multiple sclerosis. Immunol Rev (2012) 0.80
Limited protective effect of the CCR5Delta32/CCR5Delta32 genotype on human immunodeficiency virus infection incidence in a cohort of patients with hemophilia and selection for genotypic X4 virus. J Infect Dis (2003) 0.80
Stimulation of orexin/hypocretin neurones by thyrotropin-releasing hormone. J Physiol (2009) 0.79
An alternative conformation of the T-cell receptor alpha constant region. J Mol Biol (2010) 0.79
Dissection of the multiple sclerosis associated DR2 haplotype. J Autoimmun (2008) 0.78
Weighing in on autoimmune disease: Big data tip the scale. Nat Med (2013) 0.77
Multiple sclerosis: MHC associations and therapeutic implications. Expert Rev Mol Med (2005) 0.76
A clinical conundrum: the detrimental effect of TNF antagonists in multiple sclerosis. Pharmacogenomics (2013) 0.76
TCR transgenic mice that shed light on immune and environmental regulators in multiple sclerosis. J Immunol (2013) 0.75
Misfiring in multiple sclerosis: cerebellar channelopathy, a potential novel target? Ann Neurol (2012) 0.75
Axonal injury in reverse. Nat Med (2011) 0.75
Control of autoimmunity by "epitope theft". Trends Mol Med (2005) 0.75